Søgeresultater - Frese, Kristopher

Circulating tumor cells and CDX models as a tool for preclinical drug development af Lallo, Alice, Schenk, Maximilian W., Frese, Kristopher K., Blackhall, Fiona, Dive, Caroline

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A New Crucial Protein Interaction Element That Targets the Adenovirus E4-ORF1 Oncoprotein to Membrane Vesicles af Chung, Sang-Hyuk, Frese, Kristopher K., Weiss, Robert S., Prasad, B. V. Venkataram, Javier, Ronald T.

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C-Raf is required for the initiation of lung cancer by K-Ras(G12D) af Karreth, Florian A., Frese, Kristopher K., DeNicola, Gina M., Baccarini, Manuela, Tuveson, David A.

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Viral oncoprotein-induced mislocalization of select PDZ proteins disrupts tight junctions and causes polarity defects in epithelial cells af Latorre, Isabel J., Roh, Michael H., Frese, Kristopher K., Weiss, Robert S., Margolis, Ben, Javier, Ronald T.

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Progress towards non-small-cell lung cancer models that represent clinical evolutionary trajectories af Hynds, Robert E., Frese, Kristopher K., Pearce, David R., Grönroos, Eva, Dive, Caroline, Swanton, Charles

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Discs-Large and Strabismus are functionally linked to plasma membrane formation af Lee, Ok-Kyung, Frese, Kristopher K., James, Jennifer S., Chadda, Darshana, Chen, Zhi-Hong, Javier, Ronald T., Cho, Kyung-Ok

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Selective PDZ protein-dependent stimulation of phosphatidylinositol 3-kinase by the adenovirus E4-ORF1 oncoprotein af Frese, Kristopher K, Lee, Siu Sylvia, Thomas, Darby L, Latorre, Isabel J, Weiss, Robert S, Glaunsinger, Britt A, Javier, Ronald T

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nab-paclitaxel potentiates gemcitabine activity by reducing cytidine deaminase levels in a mouse model of pancreatic cancer af Frese, Kristopher K., Neesse, Albrecht, Cook, Natalie, Bapiro, Tashinga E., Lolkema, Martijn P., Jodrell, Duncan I., Tuveson, David A.

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SPARC independent drug delivery and antitumour effects of nab-paclitaxel in genetically engineered mice af Neesse, Albrecht, Frese, Kristopher K, Chan, Derek S, Bapiro, Tashinga E, Howat, William J, Richards, Frances M, Ellenrieder, Volker, Jodrell, Duncan I, Tuveson, David A

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Oncogenic function for the Dlg1 mammalian homolog of the Drosophila discs-large tumor suppressor af Frese, Kristopher K, Latorre, Isabel J, Chung, Sang-Hyuk, Caruana, Georgina, Bernstein, Alan, Jones, Stephen N, Donehower, Lawrence A, Justice, Monica J, Garner, Craig C, Javier, Ronald T

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CTGF antagonism with mAb FG-3019 enhances chemotherapy response without increasing drug delivery in murine ductal pancreas cancer af Neesse, Albrecht, Frese, Kristopher K., Bapiro, Tashinga E., Nakagawa, Tomoaki, Sternlicht, Mark D., Seeley, Todd W., Pilarsky, Christian, Jodrell, Duncan I., Spong, Suzanne M., Tuveson, David A.

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The Rare YAP1 Subtype of SCLC Revisited in a Biobank of 39 Circulating Tumor Cell Patient Derived Explant Models: A Brief Report af Pearsall, Sarah M., Humphrey, Sam, Revill, Mitchell, Morgan, Derrick, Frese, Kristopher K., Galvin, Melanie, Kerr, Alastair, Carter, Mathew, Priest, Lynsey, Blackhall, Fiona, Simpson, Kathryn L., Dive, Caroline

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PDGFR-modulated miR-23b cluster and miR-125a-5p suppress lung tumorigenesis by targeting multiple components of KRAS and NF-kB pathways af Naidu, Srivatsava, Shi, Lei, Magee, Peter, Middleton, Justin D., Laganá, Alessandro, Sahoo, Sudhakar, Leong, Hui Sun, Galvin, Melanie, Frese, Kristopher, Dive, Caroline, Guzzardo, Vincenza, Fassan, Matteo, Garofalo, Michela

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Gamma secretase inhibition promotes hypoxic necrosis in mouse pancreatic ductal adenocarcinoma af Cook, Natalie, Frese, Kristopher K., Bapiro, Tashinga E., Jacobetz, Michael A., Gopinathan, Aarthi, Miller, Jodi L., Rao, Sudhir S., Demuth, Tim, Howat, William J., Jodrell, Duncan I., Tuveson, David A.

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Expanding Therapeutic Opportunities for Extra-Pulmonary Neuroendocrine Carcinoma af Frizziero, Melissa, Kilgour, Elaine, Simpson, Kathryn L., Rothwell, Dominic G., Moore, David A., Frese, Kristopher K., Galvin, Melanie, Lamarca, Angela, Hubner, Richard A., Valle, Juan W., McNamara, Mairéad G., Dive, Caroline

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A novel method for quantification of gemcitabine and its metabolites 2′,2′-difluorodeoxyuridine and gemcitabine triphosphate in tumour tissue by LC–MS/MS: comparison with (19)F NMR... af Bapiro, Tashinga E., Richards, Frances M., Goldgraben, Mae A., Olive, Kenneth P., Madhu, Basetti, Frese, Kristopher K., Cook, Natalie, Jacobetz, Michael A., Smith, Donna-Michelle, Tuveson, David A., Griffiths, John R., Jodrell, Duncan I.

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MRI with hyperpolarised [1-(13)C]pyruvate detects advanced pancreatic preneoplasia prior to invasive disease in a mouse model af Serrao, Eva M, Kettunen, Mikko I, Rodrigues, Tiago B, Dzien, Piotr, Wright, Alan J, Gopinathan, Aarthi, Gallagher, Ferdia A, Lewis, David Y, Frese, Kristopher K, Almeida, Jaime, Howat, William J, Tuveson, David A, Brindle, Kevin M

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Signaling pathway screening platforms are an efficient approach to identify therapeutic targets in cancers that lack known driver mutations: a case report for a cancer of unknown p... af Torres-Ayuso, Pedro, Sahoo, Sudhakar, Ashton, Garry, An, Elvira, Simms, Nicole, Galvin, Melanie, Leong, Hui Sun, Frese, Kristopher K, Simpson, Kathryn, Cook, Natalie, Hughes, Andrew, Miller, Crispin J, Marais, Richard, Dive, Caroline, Krebs, Matthew G, Brognard, John

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Ex vivo culture of cells derived from circulating tumour cell xenograft to support small cell lung cancer research and experimental therapeutics af Lallo, Alice, Gulati, Sakshi, Schenk, Maximilian W, Khandelwal, Garima, Berglund, Ulrika Warpman, Pateras, Ioannis S, Chester, Christopher P E, Pham, Therese M, Kalderen, Christina, Frese, Kristopher K, Gorgoulis, Vassilis G, Miller, Crispin, Blackhall, Fiona, Helleday, Thomas, Dive, Caroline

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RhoC Interacts with Integrin α5β1 and Enhances Its Trafficking in Migrating Pancreatic Carcinoma Cells af Li, Ningfeng Fiona, Gemenetzidis, Emilios, Marshall, Francis J., Davies, Derek, Yu, Yongwei, Frese, Kristopher, Froeling, Fieke E. M., Woolf, Adam K., Feakins, Roger M., Naito, Yoshiki, Iacobuzio-Donahue, Christine, Tuveson, David A., Hart, Ian R., Kocher, Hemant M.

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