Výsledky vyhledávání - Frederick H. Wilson

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  1. 1
    WNK1, a kinase mutated in inherited hypertension with hyperkalemia, localizes to diverse Cl <sup>−</sup> -transporting epithelia

    WNK1, a kinase mutated in inherited hypertension with hyperkalemia, localizes to diverse Cl <sup>−</sup> -transporting epithelia Autor Keith A. Choate, Kristopher T. Kahle, Frederick H. Wilson, Carol Nelson‐Williams, Richard P. Lifton

    Vydáno 2003
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  2. 2
    An SGK1 site in WNK4 regulates Na <sup>+</sup> channel and K <sup>+</sup> channel activity and has implications for aldosterone signaling and K <sup>+</sup> homeostasis

    An SGK1 site in WNK4 regulates Na <sup>+</sup> channel and K <sup>+</sup> channel activity and has implications for aldosterone signaling and K <sup>+</sup> homeostasis Autor Aaron M. Ring, Qiang Leng, Jesse Rinehart, Frederick H. Wilson, Kristopher T. Kahle, Steven Hébert, Richard P. Lifton

    Vydáno 2007
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  3. 3
    WNK4 regulates apical and basolateral Cl <sup>–</sup> flux in extrarenal epithelia

    WNK4 regulates apical and basolateral Cl <sup>–</sup> flux in extrarenal epithelia Autor Kristopher T. Kahle, Ignacio Gíménez, Hatim Hassan, Frederick H. Wilson, Robert D. Wong, Biff Forbush, Peter S. Aronson, Richard P. Lifton

    Vydáno 2004
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  4. 4
    Molecular pathogenesis of inherited hypertension with hyperkalemia: The Na–Cl cotransporter is inhibited by wild-type but not mutant WNK4

    Molecular pathogenesis of inherited hypertension with hyperkalemia: The Na–Cl cotransporter is inhibited by wild-type but not mutant WNK4 Autor Frederick H. Wilson, Kristopher T. Kahle, Ernesto Sabath, Maria D. Lalioti, Alicia K. Rapson, Robert S. Hoover, Steven Hébert, Gerardo Gamba, Richard P. Lifton

    Vydáno 2003
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  5. 5
    WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl <sup>-</sup> cotransporters required for normal blood pressure homeostasis

    WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl <sup>-</sup> cotransporters required for normal blood pressure homeostasis Autor Jesse Rinehart, Kristopher T. Kahle, Paola de los Heros, Norma Vázquez, Patricia Meade, Frederick H. Wilson, Steven Hébert, Ignacio Gíménez, Gerardo Gamba, Richard P. Lifton

    Vydáno 2005
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  6. 6
    WNK4 regulates activity of the epithelial Na <sup>+</sup> channel <i>in vitro</i> and <i>in vivo</i>

    WNK4 regulates activity of the epithelial Na <sup>+</sup> channel <i>in vitro</i> and <i>in vivo</i> Autor Aaron M. Ring, Sam X. Cheng, Qiang Leng, Kristopher T. Kahle, Jesse Rinehart, Maria D. Lalioti, Heather M. Volkman, Frederick H. Wilson, Steven Hébert, Richard P. Lifton

    Vydáno 2007
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  7. 7
    Haploinsufficiency for ribosomal protein genes causes selective activation of p53 in human erythroid progenitor cells

    Haploinsufficiency for ribosomal protein genes causes selective activation of p53 in human erythroid progenitor cells Autor Shilpee Dutt, Anupama Narla, Katherine I. Lin, Ann Mullally, Nirmalee Abayasekara, Christine Megerdichian, Frederick H. Wilson, Treeve Currie, Arati Khanna‐Gupta, Nancy Berliner, Jeffery L. Kutok, Benjamin L. Ebert

    Vydáno 2010
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  8. 8
    Paracellular Cl <sup>-</sup> permeability is regulated by WNK4 kinase: Insight into normal physiology and hypertension

    Paracellular Cl <sup>-</sup> permeability is regulated by WNK4 kinase: Insight into normal physiology and hypertension Autor Kristopher T. Kahle, Gordon G. MacGregor, Frederick H. Wilson, Alfred N. Van Hoek, Dennis Brown, Thomas Ardito, Michael Kashgarian, Gerhard Giebisch, Steven C. Hebert, Emile L. Boulpaep, Richard P. Lifton

    Vydáno 2004
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  9. 9
    A Cluster of Metabolic Defects Caused by Mutation in a Mitochondrial tRNA

    A Cluster of Metabolic Defects Caused by Mutation in a Mitochondrial tRNA Autor Frederick H. Wilson, Ali Hariri, Anita Farhi, Hongyu Zhao, Kitt Falk Petersen, Hakan R. Toka, Carol Nelson‐Williams, Khalid Mehmood Raja, Michael Kashgarian, Gerald I. Shulman, Steven J. Scheinman, Richard P. Lifton

    Vydáno 2004
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  10. 10
    Genetic modifiers of EGFR dependence in non-small cell lung cancer

    Genetic modifiers of EGFR dependence in non-small cell lung cancer Autor Tanaz Sharifnia, Victor Rusu, Federica Piccioni, Mukta Bagul, Marcin Imieliński, Andrew D. Cherniack, Chandra Sekhar Pedamallu, Bang Wong, Frederick H. Wilson, Levi A. Garraway, David Altshuler, Todd R. Golub, David E. Root, Aravind Subramanian, Matthew Meyerson

    Vydáno 2014
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  11. 11
    A Functional Landscape of Resistance to ALK Inhibition in Lung Cancer

    A Functional Landscape of Resistance to ALK Inhibition in Lung Cancer Autor Frederick H. Wilson, Cory M. Johannessen, Federica Piccioni, Pablo Tamayo, Jong Wook Kim, Eliezer M. Van Allen, Steven M. Corsello, Marzia Capelletti, Antonio Calles, Mohit Butaney, Tanaz Sharifnia, Stacey B. Gabriel, Jill P. Mesirov, William C. Hahn, Jeffrey A. Engelman, Matthew Meyerson, David E. Root, Pasi A. Jänne, Levi A. Garraway

    Vydáno 2015
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  12. 12
    MAT2A inhibitor AG-270/S095033 in patients with advanced malignancies: a phase I trial

    MAT2A inhibitor AG-270/S095033 in patients with advanced malignancies: a phase I trial Autor Mrinal M. Gounder, Melissa L. Johnson, Rebecca S. Heist, Geoffrey I. Shapiro, Sophie Postel‐Vinay, Frederick H. Wilson, Elena Garralda, Gerburg M. Wulf, Caroline Almon, Salah Nabhan, Elia Aguado-Fraile, Peng He, Mathilde Romagnoli, Mohammad Ismail Hossain, Rohini Narayanaswamy, Amel Sadou-Dubourgnoux, Michael K. Cooper, Vasileios Askoxylakis, Howard A. Burris, Josep Tabernero

    Vydáno 2025
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  13. 13
    <i>MTAP</i> deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells

    <i>MTAP</i> deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells Autor Gregory V. Kryukov, Frederick H. Wilson, Jason R. Ruth, Joshiawa Paulk, Aviad Tsherniak, Sara Marlow, Francisca Vázquez, Barbara A. Weir, Mark E. Fitzgerald, Minoru Tanaka, Craig M. Bielski, Justin Scott, Courtney Dennis, Glenn S. Cowley, Jesse S. Boehm, David E. Root, Todd R. Golub, Clary B. Clish, James E. Bradner, William C. Hahn, Levi A. Garraway

    Vydáno 2016
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  14. 14
    Pembrolizumab for management of patients with NSCLC and brain metastases: long-term results and biomarker analysis from a non-randomised, open-label, phase 2 trial

    Pembrolizumab for management of patients with NSCLC and brain metastases: long-term results and biomarker analysis from a non-randomised, open-label, phase 2 trial Autor Sarah B. Goldberg, Kurt A. Schalper, Scott Gettinger, Amit Mahajan, Roy S. Herbst, Anne C. Chiang, Rogério Lilenbaum, Frederick H. Wilson, Sacit Bulent Omay, James B. Yu, Lucia B. Jilaveanu, Thuy Tran, Kira F. Pavlik, Elin Rowen, Heather Gerrish, Annette Komlo, Richa Gupta, Hailey Wyatt, Matthew Ribeiro, Yuval Kluger, Geyu Zhou, Wei Wei, Veronica Chiang, Harriet M. Kluger

    Vydáno 2020
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  15. 15
    Amplification of Wild-type <i>KRAS</i> Imparts Resistance to Crizotinib in <i>MET</i> Exon 14 Mutant Non–Small Cell Lung Cancer

    Amplification of Wild-type <i>KRAS</i> Imparts Resistance to Crizotinib in <i>MET</i> Exon 14 Mutant Non–Small Cell Lung Cancer Autor Magda Bahcall, Mark M. Awad, Lynette M. Sholl, Frederick H. Wilson, Man Xu, Stephen Wang, Sangeetha Palakurthi, Jihyun Choi, Elena Ivanova, Giulia C. Leonardi, Bryan C. Ulrich, Cloud P. Paweletz, Paul T. Kirschmeier, Masayuki Watanabe, Hideo Baba, Mizuki Nishino, Rebecca J. Nagy, Richard B. Lanman, Marzia Capelletti, Emily S. Chambers, Amanda J. Redig, Paul A. VanderLaan, Daniel B. Costa, Yu Imamura, Pasi A. Jänne

    Vydáno 2018
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  16. 16
    Assigning clinical meaning to somatic and germ-line whole-exome sequencing data in a prospective cancer precision medicine study

    Assigning clinical meaning to somatic and germ-line whole-exome sequencing data in a prospective cancer precision medicine study Autor Arezou A. Ghazani, Nelly Oliver, Joseph P. St. Pierre, Andrea Garofalo, Irene Rainville, Elaine Hiller, Daniel J. Treacy, Vanesa Rojas‐Rudilla, Sam Wood, Elizabeth F. Bair, Michael Parello, Franklin W. Huang, Marios Giannakis, Frederick H. Wilson, Elizabeth H. Stover, Steven M. Corsello, Tom Nguyen, Huma Q. Rana, Alanna J. Church, Carol Lowenstein, Carrie Cibulskis, Ali Amin‐Mansour, Jennifer Heng, Lauren K. Brais, Abigail Santos, Michael Bauer, Amanda Waldron, Peter Lo, Megan J. Gorman, Christine Lydon, Marisa W. Welch, Philip G. McNamara, Stacey Gabriel, Lynette M. Sholl, Neal I. Lindeman, Judy E. Garber, Steven Joffe, Eliezer M. Van Allen, Stacy W. Gray, Pasi A. Jänne, Levi A. Garraway, Nikhil Wagle

    Vydáno 2017
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