Ngā hua rapu kaituhi :: APM

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WNK1, a kinase mutated in inherited hypertension with hyperkalemia, localizes to diverse Cl <sup>−</sup> -transporting epithelia mā Keith A. Choate, Kristopher T. Kahle, Frederick H. Wilson, Carol Nelson‐Williams, Richard P. Lifton

I whakaputaina 2003

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Artigo

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2

An SGK1 site in WNK4 regulates Na <sup>+</sup> channel and K <sup>+</sup> channel activity and has implications for aldosterone signaling and K <sup>+</sup> homeostasis mā Aaron M. Ring, Qiang Leng, Jesse Rinehart, Frederick H. Wilson, Kristopher T. Kahle, Steven Hébert, Richard P. Lifton

I whakaputaina 2007

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Artigo

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3

WNK4 regulates apical and basolateral Cl <sup>–</sup> flux in extrarenal epithelia mā Kristopher T. Kahle, Ignacio Gíménez, Hatim Hassan, Frederick H. Wilson, Robert D. Wong, Biff Forbush, Peter S. Aronson, Richard P. Lifton

I whakaputaina 2004

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Artigo

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4

Molecular pathogenesis of inherited hypertension with hyperkalemia: The Na–Cl cotransporter is inhibited by wild-type but not mutant WNK4 mā Frederick H. Wilson, Kristopher T. Kahle, Ernesto Sabath, Maria D. Lalioti, Alicia K. Rapson, Robert S. Hoover, Steven Hébert, Gerardo Gamba, Richard P. Lifton

I whakaputaina 2003

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Artigo

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5

WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl <sup>-</sup> cotransporters required for normal blood pressure homeostasis mā Jesse Rinehart, Kristopher T. Kahle, Paola de los Heros, Norma Vázquez, Patricia Meade, Frederick H. Wilson, Steven Hébert, Ignacio Gíménez, Gerardo Gamba, Richard P. Lifton

I whakaputaina 2005

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Artigo

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6

WNK4 regulates activity of the epithelial Na <sup>+</sup> channel <i>in vitro</i> and <i>in vivo</i> mā Aaron M. Ring, Sam X. Cheng, Qiang Leng, Kristopher T. Kahle, Jesse Rinehart, Maria D. Lalioti, Heather M. Volkman, Frederick H. Wilson, Steven Hébert, Richard P. Lifton

I whakaputaina 2007

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Artigo

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7

Haploinsufficiency for ribosomal protein genes causes selective activation of p53 in human erythroid progenitor cells mā Shilpee Dutt, Anupama Narla, Katherine I. Lin, Ann Mullally, Nirmalee Abayasekara, Christine Megerdichian, Frederick H. Wilson, Treeve Currie, Arati Khanna‐Gupta, Nancy Berliner, Jeffery L. Kutok, Benjamin L. Ebert

I whakaputaina 2010

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Artigo

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Paracellular Cl <sup>-</sup> permeability is regulated by WNK4 kinase: Insight into normal physiology and hypertension mā Kristopher T. Kahle, Gordon G. MacGregor, Frederick H. Wilson, Alfred N. Van Hoek, Dennis Brown, Thomas Ardito, Michael Kashgarian, Gerhard Giebisch, Steven C. Hebert, Emile L. Boulpaep, Richard P. Lifton

I whakaputaina 2004

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Artigo

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9

A Cluster of Metabolic Defects Caused by Mutation in a Mitochondrial tRNA mā Frederick H. Wilson, Ali Hariri, Anita Farhi, Hongyu Zhao, Kitt Falk Petersen, Hakan R. Toka, Carol Nelson‐Williams, Khalid Mehmood Raja, Michael Kashgarian, Gerald I. Shulman, Steven J. Scheinman, Richard P. Lifton

I whakaputaina 2004

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Artigo

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10

Genetic modifiers of EGFR dependence in non-small cell lung cancer mā Tanaz Sharifnia, Victor Rusu, Federica Piccioni, Mukta Bagul, Marcin Imieliński, Andrew D. Cherniack, Chandra Sekhar Pedamallu, Bang Wong, Frederick H. Wilson, Levi A. Garraway, David Altshuler, Todd R. Golub, David E. Root, Aravind Subramanian, Matthew Meyerson

I whakaputaina 2014

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Artigo

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11

A Functional Landscape of Resistance to ALK Inhibition in Lung Cancer mā Frederick H. Wilson, Cory M. Johannessen, Federica Piccioni, Pablo Tamayo, Jong Wook Kim, Eliezer M. Van Allen, Steven M. Corsello, Marzia Capelletti, Antonio Calles, Mohit Butaney, Tanaz Sharifnia, Stacey B. Gabriel, Jill P. Mesirov, William C. Hahn, Jeffrey A. Engelman, Matthew Meyerson, David E. Root, Pasi A. Jänne, Levi A. Garraway

I whakaputaina 2015

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Artigo

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12

MAT2A inhibitor AG-270/S095033 in patients with advanced malignancies: a phase I trial mā Mrinal M. Gounder, Melissa L. Johnson, Rebecca S. Heist, Geoffrey I. Shapiro, Sophie Postel‐Vinay, Frederick H. Wilson, Elena Garralda, Gerburg M. Wulf, Caroline Almon, Salah Nabhan, Elia Aguado-Fraile, Peng He, Mathilde Romagnoli, Mohammad Ismail Hossain, Rohini Narayanaswamy, Amel Sadou-Dubourgnoux, Michael K. Cooper, Vasileios Askoxylakis, Howard A. Burris, Josep Tabernero

I whakaputaina 2025

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Artigo

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13

<i>MTAP</i> deletion confers enhanced dependency on the PRMT5 arginine methyltransferase in cancer cells mā Gregory V. Kryukov, Frederick H. Wilson, Jason R. Ruth, Joshiawa Paulk, Aviad Tsherniak, Sara Marlow, Francisca Vázquez, Barbara A. Weir, Mark E. Fitzgerald, Minoru Tanaka, Craig M. Bielski, Justin Scott, Courtney Dennis, Glenn S. Cowley, Jesse S. Boehm, David E. Root, Todd R. Golub, Clary B. Clish, James E. Bradner, William C. Hahn, Levi A. Garraway

I whakaputaina 2016

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Artigo

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14

Pembrolizumab for management of patients with NSCLC and brain metastases: long-term results and biomarker analysis from a non-randomised, open-label, phase 2 trial mā Sarah B. Goldberg, Kurt A. Schalper, Scott Gettinger, Amit Mahajan, Roy S. Herbst, Anne C. Chiang, Rogério Lilenbaum, Frederick H. Wilson, Sacit Bulent Omay, James B. Yu, Lucia B. Jilaveanu, Thuy Tran, Kira F. Pavlik, Elin Rowen, Heather Gerrish, Annette Komlo, Richa Gupta, Hailey Wyatt, Matthew Ribeiro, Yuval Kluger, Geyu Zhou, Wei Wei, Veronica Chiang, Harriet M. Kluger

I whakaputaina 2020

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15

Amplification of Wild-type <i>KRAS</i> Imparts Resistance to Crizotinib in <i>MET</i> Exon 14 Mutant Non–Small Cell Lung Cancer mā Magda Bahcall, Mark M. Awad, Lynette M. Sholl, Frederick H. Wilson, Man Xu, Stephen Wang, Sangeetha Palakurthi, Jihyun Choi, Elena Ivanova, Giulia C. Leonardi, Bryan C. Ulrich, Cloud P. Paweletz, Paul T. Kirschmeier, Masayuki Watanabe, Hideo Baba, Mizuki Nishino, Rebecca J. Nagy, Richard B. Lanman, Marzia Capelletti, Emily S. Chambers, Amanda J. Redig, Paul A. VanderLaan, Daniel B. Costa, Yu Imamura, Pasi A. Jänne

I whakaputaina 2018

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Artigo

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16

Assigning clinical meaning to somatic and germ-line whole-exome sequencing data in a prospective cancer precision medicine study mā Arezou A. Ghazani, Nelly Oliver, Joseph P. St. Pierre, Andrea Garofalo, Irene Rainville, Elaine Hiller, Daniel J. Treacy, Vanesa Rojas‐Rudilla, Sam Wood, Elizabeth F. Bair, Michael Parello, Franklin W. Huang, Marios Giannakis, Frederick H. Wilson, Elizabeth H. Stover, Steven M. Corsello, Tom Nguyen, Huma Q. Rana, Alanna J. Church, Carol Lowenstein, Carrie Cibulskis, Ali Amin‐Mansour, Jennifer Heng, Lauren K. Brais, Abigail Santos, Michael Bauer, Amanda Waldron, Peter Lo, Megan J. Gorman, Christine Lydon, Marisa W. Welch, Philip G. McNamara, Stacey Gabriel, Lynette M. Sholl, Neal I. Lindeman, Judy E. Garber, Steven Joffe, Eliezer M. Van Allen, Stacy W. Gray, Pasi A. Jänne, Levi A. Garraway, Nikhil Wagle

I whakaputaina 2017

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Artigo

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