检索结果 - Frattini, Mark G

An exo-cell assay for examining real-time γ-secretase activity and inhibition 由 Shelton, Christopher C, Tian, Yuan, Frattini, Mark G, Li, Yue-Ming

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Geminin Inhibits a Late Step in the Formation of Human Pre-replicative Complexes 由 Wu, Min, Lu, Wenyan, Santos, Ruth E., Frattini, Mark G., Kelly, Thomas J.

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Redundant control of rereplication in fission yeast 由 Gopalakrishnan, Vidya, Simancek, Pamela, Houchens, Christopher, Snaith, Hilary A., Frattini, Mark G., Sazer, Shelley, Kelly, Thomas J.

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Multiple Mechanisms Contribute to Schizosaccharomyces pombe Origin Recognition Complex-DNA Interactions 由 Houchens, Christopher R., Lu, Wenyan, Chuang, Ray-Yuan, Frattini, Mark G., Fuller, Alex, Simancek, Pam, Kelly, Thomas J.

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Identification of benzofuran-4,5-diones as novel and selective non-hydroxamic acid, non-peptidomimetic based inhibitors of human peptide deformylase 由 Antczak, Christophe, Shum, David, Bassit, Bhramdeo, Frattini, Mark G., Li, Yueming, de Stanchina, Elisa, Scheinberg, David A., Djaballah, Hakim

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An Arrayed Genome-Scale Lentiviral-Enabled Short Hairpin RNA Screen Identifies Lethal and Rescuer Gene Candidates 由 Bhinder, Bhavneet, Antczak, Christophe, Ramirez, Christina N., Shum, David, Liu-Sullivan, Nancy, Radu, Constantin, Frattini, Mark G., Djaballah, Hakim

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Comparison of Luminescence ADP Production Assay and Radiometric Scintillation Proximity Assay for Cdc7 Kinase 由 Takagi, Toshimitsu, Shum, David, Parisi, Monika, Santos, Ruth E., Radu, Constantin, Calder, Paul, Rizvi, Zahra, Frattini, Mark G., Djaballah, Hakim

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Kinase-dead ATR differs from ATR loss by limiting the dynamic exchange of ATR and RPA 由 Menolfi, Demis, Jiang, Wenxia, Lee, Brian J., Moiseeva, Tatiana, Shao, Zhengping, Estes, Verna, Frattini, Mark G., Bakkenist, Christopher J., Zha, Shan

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Relative Mitochondrial Priming of Malignant Myeloblasts and Normal HSCs Determines Chemotherapeutic Success in AML 由 Vo, Thanh-Trang, Ryan, Jeremy, Carrasco, Ruben, Neuberg, Donna, Rossi, Derrick J., Stone, Richard, DeAngelo, Daniel J., Frattini, Mark G., Letai, Anthony

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Structure-activity relationships of 6-(2,6-dichlorophenyl)-8-methyl-2-(phenylamino)pyrido[2,3-d]pyrimidin-7-ones: toward selective Abl inhibitors 由 Antczak, Christophe, Veach, Darren R., Ramirez, Christina N., Minchenko, Maria A., Shum, David, Calder, Paul A., Frattini, Mark G., Clarkson, Bayard, Djaballah, Hakim

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Micafungin Versus Posaconazole Prophylaxis in Acute Leukemia or Myelodysplastic Syndrome: A Randomized Study 由 Epstein, David J., Seo, Susan K., Huang, Yao-Ting, Park, Jay H., Klimek, Virginia M., Berman, Ellin, Tallman, Martin S., Frattini, Mark G., Papanicolaou, Genovefa A.

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Human DDK rescues stalled forks and counteracts checkpoint inhibition at unfired origins to complete DNA replication 由 Jones, Mathew J.K., Gelot, Camille, Munk, Stephanie, Koren, Amnon, Kawasoe, Yoshitaka, George, Kelly A., Santos, Ruth E., Olsen, Jesper V., McCarroll, Steven A., Frattini, Mark G., Takahashi, Tatsuro S., Jallepalli, Prasad V.

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Treatment of Patients with Acute Myeloid Leukemia with the Targeted Alpha-Particle Nano-Generator Actinium-225-Lintuzumab 由 Rosenblat, Todd L., McDevitt, Michael R., Carrasquillo, Jorge A., Pandit-Taskar, Neeta, Frattini, Mark G., Maslak, Peter G., Park, Jae H., Douer, Dan, Cicic, Dragan, Larson, Steven M., Scheinberg, David A., Jurcic, Joseph G.

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Vaccination with synthetic analog peptides derived from WT1 oncoprotein induces T-cell responses in patients with complete remission from acute myeloid leukemia 由 Maslak, Peter G., Dao, Tao, Krug, Lee M., Chanel, Suzanne, Korontsvit, Tatyana, Zakhaleva, Victoria, Zhang, Ronghua, Wolchok, Jedd D., Yuan, Jianda, Pinilla-Ibarz, Javier, Berman, Ellin, Weiss, Mark, Jurcic, Joseph, Frattini, Mark G., Scheinberg, David A.

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Improved survival with enasidenib versus standard of care in relapsed/refractory acute myeloid leukemia associated with IDH2 mutations using historical data and propensity score ma... 由 de Botton, Stéphane, Brandwein, Joseph M., Wei, Andrew H., Pigneux, Arnaud, Quesnel, Bruno, Thomas, Xavier, Legrand, Ollivier, Recher, Christian, Chantepie, Sylvain, Hunault‐Berger, Mathilde, Boissel, Nicolas, Nehme, Salem A., Frattini, Mark G., Tosolini, Alessandra, Marion‐Gallois, Roland, Wang, Jixian J., Cameron, Chris, Siddiqui, Muhaimen, Hutton, Brian, Milkovich, Gary, Stein, Eytan M.

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A Multi-center Phase I Trial of Ipilimumab in Patients with Myelodysplastic Syndromes following Hypomethylating Agent Failure 由 Zeidan, Amer M., Knaus, Hanna A., Robinson, Tara M., Towlerton, Andrea M.H., Warren, Edus H., Zeidner, Joshua F., Blackford, Amanda L., Duffield, Amy S., Rizzieri, David, Frattini, Mark G., Levy, Yair M., Schroeder, Mark A., Ferguson, Anna, Sheldon, Katherine E., DeZern, Amy E., Gojo, Ivana, Gore, Steven D., Streicher, Howard, Luznik, Leo, Smith, B. Douglas

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Mutant Isocitrate Dehydrogenase 1 Inhibitor Ivosidenib in Combination With Azacitidine for Newly Diagnosed Acute Myeloid Leukemia 由 DiNardo, Courtney D., Stein, Anthony S., Stein, Eytan M., Fathi, Amir T., Frankfurt, Olga, Schuh, Andre C., Döhner, Hartmut, Martinelli, Giovanni, Patel, Prapti A., Raffoux, Emmanuel, Tan, Peter, Zeidan, Amer M., de Botton, Stéphane, Kantarjian, Hagop M., Stone, Richard M., Frattini, Mark G., Lersch, Frederik, Gong, Jing, Gianolio, Diego A., Zhang, Vickie, Franovic, Aleksandra, Fan, Bin, Goldwasser, Meredith, Daigle, Scott, Choe, Sung, Wu, Bin, Winkler, Thomas, Vyas, Paresh

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Ivosidenib or enasidenib combined with intensive chemotherapy in patients with newly diagnosed AML: a phase 1 study 由 Stein, Eytan M., DiNardo, Courtney D., Fathi, Amir T., Mims, Alice S., Pratz, Keith W., Savona, Michael R., Stein, Anthony S., Stone, Richard M., Winer, Eric S., Seet, Christopher S., Döhner, Hartmut, Pollyea, Daniel A., McCloskey, James K., Odenike, Olatoyosi, Löwenberg, Bob, Ossenkoppele, Gert J., Patel, Prapti A., Roshal, Mikhail, Frattini, Mark G., Lersch, Frederik, Franovic, Aleksandra, Nabhan, Salah, Fan, Bin, Choe, Sung, Wang, Hongfang, Wu, Bin, Hua, Lei, Almon, Caroline, Cooper, Michael, Kantarjian, Hagop M., Tallman, Martin S.

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Clonal diversity predicts adverse outcome in chronic lymphocytic leukemia 由 Leeksma, Alexander C., Taylor, Justin, Wu, Bian, Gardner, Jeffrey R., He, Jie, Nahas, Michelle, Gonen, Mithat, Alemayehu, Wendimagegn G., te Raa, Doreen, Walther, Tatjana, Hüllein, Jennifer, Dietrich, Sascha, Claus, Rainer, de Boer, Fransien, de Heer, Koen, Dubois, Julie, Dampmann, Maria, Dürig, Jan, van Oers, Marinus H. J., Geisler, Christian H., Eldering, Eric, Levine, Ross L., Miller, Vincent, Mughal, Tariq, Lamanna, Nicole, Frattini, Mark G., Heaney, Mark L., Zelenetz, Andrew, Zenz, Thorsten, Abdel-Wahab, Omar, Kater, Arnon P.

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Isoform Switching as a Mechanism of Acquired Resistance to Mutant Isocitrate Dehydrogenase Inhibition 由 Harding, James J., Lowery, Maeve A., Shih, Alan H., Schvartzman, Juan M., Hou, Shengqi, Famulare, Christopher, Patel, Minal, Roshal, Mikhail, Do, Richard K., Zehir, Ahmet, You, Daoqi, Selcuklu, S. Duygu, Viale, Agnes, Tallman, Martin S., Hyman, David M., Reznik, Ed, Finley, Lydia W.S., Papaemmanuil, Elli, Tosolini, Alessandra, Frattini, Mark G., MacBeth, Kyle J., Liu, Guowen, Fan, Bin, Choe, Sung, Wu, Bin, Janjigian, Yelena Y., Mellinghoff, Ingo K., Diaz, Luis A., Levine, Ross L., Abou-Alfa, Ghassan K., Stein, Eytan M., Intlekofer, Andrew M.

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