Torthaí cuardaigh - Frattini, Mark G

An exo-cell assay for examining real-time γ-secretase activity and inhibition de réir Shelton, Christopher C, Tian, Yuan, Frattini, Mark G, Li, Yue-Ming

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Geminin Inhibits a Late Step in the Formation of Human Pre-replicative Complexes de réir Wu, Min, Lu, Wenyan, Santos, Ruth E., Frattini, Mark G., Kelly, Thomas J.

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Redundant control of rereplication in fission yeast de réir Gopalakrishnan, Vidya, Simancek, Pamela, Houchens, Christopher, Snaith, Hilary A., Frattini, Mark G., Sazer, Shelley, Kelly, Thomas J.

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Multiple Mechanisms Contribute to Schizosaccharomyces pombe Origin Recognition Complex-DNA Interactions de réir Houchens, Christopher R., Lu, Wenyan, Chuang, Ray-Yuan, Frattini, Mark G., Fuller, Alex, Simancek, Pam, Kelly, Thomas J.

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Identification of benzofuran-4,5-diones as novel and selective non-hydroxamic acid, non-peptidomimetic based inhibitors of human peptide deformylase de réir Antczak, Christophe, Shum, David, Bassit, Bhramdeo, Frattini, Mark G., Li, Yueming, de Stanchina, Elisa, Scheinberg, David A., Djaballah, Hakim

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An Arrayed Genome-Scale Lentiviral-Enabled Short Hairpin RNA Screen Identifies Lethal and Rescuer Gene Candidates de réir Bhinder, Bhavneet, Antczak, Christophe, Ramirez, Christina N., Shum, David, Liu-Sullivan, Nancy, Radu, Constantin, Frattini, Mark G., Djaballah, Hakim

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Comparison of Luminescence ADP Production Assay and Radiometric Scintillation Proximity Assay for Cdc7 Kinase de réir Takagi, Toshimitsu, Shum, David, Parisi, Monika, Santos, Ruth E., Radu, Constantin, Calder, Paul, Rizvi, Zahra, Frattini, Mark G., Djaballah, Hakim

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Kinase-dead ATR differs from ATR loss by limiting the dynamic exchange of ATR and RPA de réir Menolfi, Demis, Jiang, Wenxia, Lee, Brian J., Moiseeva, Tatiana, Shao, Zhengping, Estes, Verna, Frattini, Mark G., Bakkenist, Christopher J., Zha, Shan

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Relative Mitochondrial Priming of Malignant Myeloblasts and Normal HSCs Determines Chemotherapeutic Success in AML de réir Vo, Thanh-Trang, Ryan, Jeremy, Carrasco, Ruben, Neuberg, Donna, Rossi, Derrick J., Stone, Richard, DeAngelo, Daniel J., Frattini, Mark G., Letai, Anthony

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Structure-activity relationships of 6-(2,6-dichlorophenyl)-8-methyl-2-(phenylamino)pyrido[2,3-d]pyrimidin-7-ones: toward selective Abl inhibitors de réir Antczak, Christophe, Veach, Darren R., Ramirez, Christina N., Minchenko, Maria A., Shum, David, Calder, Paul A., Frattini, Mark G., Clarkson, Bayard, Djaballah, Hakim

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Micafungin Versus Posaconazole Prophylaxis in Acute Leukemia or Myelodysplastic Syndrome: A Randomized Study de réir Epstein, David J., Seo, Susan K., Huang, Yao-Ting, Park, Jay H., Klimek, Virginia M., Berman, Ellin, Tallman, Martin S., Frattini, Mark G., Papanicolaou, Genovefa A.

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Human DDK rescues stalled forks and counteracts checkpoint inhibition at unfired origins to complete DNA replication de réir Jones, Mathew J.K., Gelot, Camille, Munk, Stephanie, Koren, Amnon, Kawasoe, Yoshitaka, George, Kelly A., Santos, Ruth E., Olsen, Jesper V., McCarroll, Steven A., Frattini, Mark G., Takahashi, Tatsuro S., Jallepalli, Prasad V.

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Treatment of Patients with Acute Myeloid Leukemia with the Targeted Alpha-Particle Nano-Generator Actinium-225-Lintuzumab de réir Rosenblat, Todd L., McDevitt, Michael R., Carrasquillo, Jorge A., Pandit-Taskar, Neeta, Frattini, Mark G., Maslak, Peter G., Park, Jae H., Douer, Dan, Cicic, Dragan, Larson, Steven M., Scheinberg, David A., Jurcic, Joseph G.

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Vaccination with synthetic analog peptides derived from WT1 oncoprotein induces T-cell responses in patients with complete remission from acute myeloid leukemia de réir Maslak, Peter G., Dao, Tao, Krug, Lee M., Chanel, Suzanne, Korontsvit, Tatyana, Zakhaleva, Victoria, Zhang, Ronghua, Wolchok, Jedd D., Yuan, Jianda, Pinilla-Ibarz, Javier, Berman, Ellin, Weiss, Mark, Jurcic, Joseph, Frattini, Mark G., Scheinberg, David A.

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Improved survival with enasidenib versus standard of care in relapsed/refractory acute myeloid leukemia associated with IDH2 mutations using historical data and propensity score ma... de réir de Botton, Stéphane, Brandwein, Joseph M., Wei, Andrew H., Pigneux, Arnaud, Quesnel, Bruno, Thomas, Xavier, Legrand, Ollivier, Recher, Christian, Chantepie, Sylvain, Hunault‐Berger, Mathilde, Boissel, Nicolas, Nehme, Salem A., Frattini, Mark G., Tosolini, Alessandra, Marion‐Gallois, Roland, Wang, Jixian J., Cameron, Chris, Siddiqui, Muhaimen, Hutton, Brian, Milkovich, Gary, Stein, Eytan M.

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A Multi-center Phase I Trial of Ipilimumab in Patients with Myelodysplastic Syndromes following Hypomethylating Agent Failure de réir Zeidan, Amer M., Knaus, Hanna A., Robinson, Tara M., Towlerton, Andrea M.H., Warren, Edus H., Zeidner, Joshua F., Blackford, Amanda L., Duffield, Amy S., Rizzieri, David, Frattini, Mark G., Levy, Yair M., Schroeder, Mark A., Ferguson, Anna, Sheldon, Katherine E., DeZern, Amy E., Gojo, Ivana, Gore, Steven D., Streicher, Howard, Luznik, Leo, Smith, B. Douglas

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Mutant Isocitrate Dehydrogenase 1 Inhibitor Ivosidenib in Combination With Azacitidine for Newly Diagnosed Acute Myeloid Leukemia de réir DiNardo, Courtney D., Stein, Anthony S., Stein, Eytan M., Fathi, Amir T., Frankfurt, Olga, Schuh, Andre C., Döhner, Hartmut, Martinelli, Giovanni, Patel, Prapti A., Raffoux, Emmanuel, Tan, Peter, Zeidan, Amer M., de Botton, Stéphane, Kantarjian, Hagop M., Stone, Richard M., Frattini, Mark G., Lersch, Frederik, Gong, Jing, Gianolio, Diego A., Zhang, Vickie, Franovic, Aleksandra, Fan, Bin, Goldwasser, Meredith, Daigle, Scott, Choe, Sung, Wu, Bin, Winkler, Thomas, Vyas, Paresh

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Ivosidenib or enasidenib combined with intensive chemotherapy in patients with newly diagnosed AML: a phase 1 study de réir Stein, Eytan M., DiNardo, Courtney D., Fathi, Amir T., Mims, Alice S., Pratz, Keith W., Savona, Michael R., Stein, Anthony S., Stone, Richard M., Winer, Eric S., Seet, Christopher S., Döhner, Hartmut, Pollyea, Daniel A., McCloskey, James K., Odenike, Olatoyosi, Löwenberg, Bob, Ossenkoppele, Gert J., Patel, Prapti A., Roshal, Mikhail, Frattini, Mark G., Lersch, Frederik, Franovic, Aleksandra, Nabhan, Salah, Fan, Bin, Choe, Sung, Wang, Hongfang, Wu, Bin, Hua, Lei, Almon, Caroline, Cooper, Michael, Kantarjian, Hagop M., Tallman, Martin S.

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Clonal diversity predicts adverse outcome in chronic lymphocytic leukemia de réir Leeksma, Alexander C., Taylor, Justin, Wu, Bian, Gardner, Jeffrey R., He, Jie, Nahas, Michelle, Gonen, Mithat, Alemayehu, Wendimagegn G., te Raa, Doreen, Walther, Tatjana, Hüllein, Jennifer, Dietrich, Sascha, Claus, Rainer, de Boer, Fransien, de Heer, Koen, Dubois, Julie, Dampmann, Maria, Dürig, Jan, van Oers, Marinus H. J., Geisler, Christian H., Eldering, Eric, Levine, Ross L., Miller, Vincent, Mughal, Tariq, Lamanna, Nicole, Frattini, Mark G., Heaney, Mark L., Zelenetz, Andrew, Zenz, Thorsten, Abdel-Wahab, Omar, Kater, Arnon P.

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Isoform Switching as a Mechanism of Acquired Resistance to Mutant Isocitrate Dehydrogenase Inhibition de réir Harding, James J., Lowery, Maeve A., Shih, Alan H., Schvartzman, Juan M., Hou, Shengqi, Famulare, Christopher, Patel, Minal, Roshal, Mikhail, Do, Richard K., Zehir, Ahmet, You, Daoqi, Selcuklu, S. Duygu, Viale, Agnes, Tallman, Martin S., Hyman, David M., Reznik, Ed, Finley, Lydia W.S., Papaemmanuil, Elli, Tosolini, Alessandra, Frattini, Mark G., MacBeth, Kyle J., Liu, Guowen, Fan, Bin, Choe, Sung, Wu, Bin, Janjigian, Yelena Y., Mellinghoff, Ingo K., Diaz, Luis A., Levine, Ross L., Abou-Alfa, Ghassan K., Stein, Eytan M., Intlekofer, Andrew M.

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