Canlyniadau Chwilio - Frattini, Mark G

An exo-cell assay for examining real-time γ-secretase activity and inhibition gan Shelton, Christopher C, Tian, Yuan, Frattini, Mark G, Li, Yue-Ming

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Geminin Inhibits a Late Step in the Formation of Human Pre-replicative Complexes gan Wu, Min, Lu, Wenyan, Santos, Ruth E., Frattini, Mark G., Kelly, Thomas J.

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Redundant control of rereplication in fission yeast gan Gopalakrishnan, Vidya, Simancek, Pamela, Houchens, Christopher, Snaith, Hilary A., Frattini, Mark G., Sazer, Shelley, Kelly, Thomas J.

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Multiple Mechanisms Contribute to Schizosaccharomyces pombe Origin Recognition Complex-DNA Interactions gan Houchens, Christopher R., Lu, Wenyan, Chuang, Ray-Yuan, Frattini, Mark G., Fuller, Alex, Simancek, Pam, Kelly, Thomas J.

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Identification of benzofuran-4,5-diones as novel and selective non-hydroxamic acid, non-peptidomimetic based inhibitors of human peptide deformylase gan Antczak, Christophe, Shum, David, Bassit, Bhramdeo, Frattini, Mark G., Li, Yueming, de Stanchina, Elisa, Scheinberg, David A., Djaballah, Hakim

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An Arrayed Genome-Scale Lentiviral-Enabled Short Hairpin RNA Screen Identifies Lethal and Rescuer Gene Candidates gan Bhinder, Bhavneet, Antczak, Christophe, Ramirez, Christina N., Shum, David, Liu-Sullivan, Nancy, Radu, Constantin, Frattini, Mark G., Djaballah, Hakim

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Comparison of Luminescence ADP Production Assay and Radiometric Scintillation Proximity Assay for Cdc7 Kinase gan Takagi, Toshimitsu, Shum, David, Parisi, Monika, Santos, Ruth E., Radu, Constantin, Calder, Paul, Rizvi, Zahra, Frattini, Mark G., Djaballah, Hakim

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Kinase-dead ATR differs from ATR loss by limiting the dynamic exchange of ATR and RPA gan Menolfi, Demis, Jiang, Wenxia, Lee, Brian J., Moiseeva, Tatiana, Shao, Zhengping, Estes, Verna, Frattini, Mark G., Bakkenist, Christopher J., Zha, Shan

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Relative Mitochondrial Priming of Malignant Myeloblasts and Normal HSCs Determines Chemotherapeutic Success in AML gan Vo, Thanh-Trang, Ryan, Jeremy, Carrasco, Ruben, Neuberg, Donna, Rossi, Derrick J., Stone, Richard, DeAngelo, Daniel J., Frattini, Mark G., Letai, Anthony

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Structure-activity relationships of 6-(2,6-dichlorophenyl)-8-methyl-2-(phenylamino)pyrido[2,3-d]pyrimidin-7-ones: toward selective Abl inhibitors gan Antczak, Christophe, Veach, Darren R., Ramirez, Christina N., Minchenko, Maria A., Shum, David, Calder, Paul A., Frattini, Mark G., Clarkson, Bayard, Djaballah, Hakim

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Micafungin Versus Posaconazole Prophylaxis in Acute Leukemia or Myelodysplastic Syndrome: A Randomized Study gan Epstein, David J., Seo, Susan K., Huang, Yao-Ting, Park, Jay H., Klimek, Virginia M., Berman, Ellin, Tallman, Martin S., Frattini, Mark G., Papanicolaou, Genovefa A.

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Human DDK rescues stalled forks and counteracts checkpoint inhibition at unfired origins to complete DNA replication gan Jones, Mathew J.K., Gelot, Camille, Munk, Stephanie, Koren, Amnon, Kawasoe, Yoshitaka, George, Kelly A., Santos, Ruth E., Olsen, Jesper V., McCarroll, Steven A., Frattini, Mark G., Takahashi, Tatsuro S., Jallepalli, Prasad V.

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Treatment of Patients with Acute Myeloid Leukemia with the Targeted Alpha-Particle Nano-Generator Actinium-225-Lintuzumab gan Rosenblat, Todd L., McDevitt, Michael R., Carrasquillo, Jorge A., Pandit-Taskar, Neeta, Frattini, Mark G., Maslak, Peter G., Park, Jae H., Douer, Dan, Cicic, Dragan, Larson, Steven M., Scheinberg, David A., Jurcic, Joseph G.

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Vaccination with synthetic analog peptides derived from WT1 oncoprotein induces T-cell responses in patients with complete remission from acute myeloid leukemia gan Maslak, Peter G., Dao, Tao, Krug, Lee M., Chanel, Suzanne, Korontsvit, Tatyana, Zakhaleva, Victoria, Zhang, Ronghua, Wolchok, Jedd D., Yuan, Jianda, Pinilla-Ibarz, Javier, Berman, Ellin, Weiss, Mark, Jurcic, Joseph, Frattini, Mark G., Scheinberg, David A.

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Improved survival with enasidenib versus standard of care in relapsed/refractory acute myeloid leukemia associated with IDH2 mutations using historical data and propensity score ma... gan de Botton, Stéphane, Brandwein, Joseph M., Wei, Andrew H., Pigneux, Arnaud, Quesnel, Bruno, Thomas, Xavier, Legrand, Ollivier, Recher, Christian, Chantepie, Sylvain, Hunault‐Berger, Mathilde, Boissel, Nicolas, Nehme, Salem A., Frattini, Mark G., Tosolini, Alessandra, Marion‐Gallois, Roland, Wang, Jixian J., Cameron, Chris, Siddiqui, Muhaimen, Hutton, Brian, Milkovich, Gary, Stein, Eytan M.

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A Multi-center Phase I Trial of Ipilimumab in Patients with Myelodysplastic Syndromes following Hypomethylating Agent Failure gan Zeidan, Amer M., Knaus, Hanna A., Robinson, Tara M., Towlerton, Andrea M.H., Warren, Edus H., Zeidner, Joshua F., Blackford, Amanda L., Duffield, Amy S., Rizzieri, David, Frattini, Mark G., Levy, Yair M., Schroeder, Mark A., Ferguson, Anna, Sheldon, Katherine E., DeZern, Amy E., Gojo, Ivana, Gore, Steven D., Streicher, Howard, Luznik, Leo, Smith, B. Douglas

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Mutant Isocitrate Dehydrogenase 1 Inhibitor Ivosidenib in Combination With Azacitidine for Newly Diagnosed Acute Myeloid Leukemia gan DiNardo, Courtney D., Stein, Anthony S., Stein, Eytan M., Fathi, Amir T., Frankfurt, Olga, Schuh, Andre C., Döhner, Hartmut, Martinelli, Giovanni, Patel, Prapti A., Raffoux, Emmanuel, Tan, Peter, Zeidan, Amer M., de Botton, Stéphane, Kantarjian, Hagop M., Stone, Richard M., Frattini, Mark G., Lersch, Frederik, Gong, Jing, Gianolio, Diego A., Zhang, Vickie, Franovic, Aleksandra, Fan, Bin, Goldwasser, Meredith, Daigle, Scott, Choe, Sung, Wu, Bin, Winkler, Thomas, Vyas, Paresh

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Ivosidenib or enasidenib combined with intensive chemotherapy in patients with newly diagnosed AML: a phase 1 study gan Stein, Eytan M., DiNardo, Courtney D., Fathi, Amir T., Mims, Alice S., Pratz, Keith W., Savona, Michael R., Stein, Anthony S., Stone, Richard M., Winer, Eric S., Seet, Christopher S., Döhner, Hartmut, Pollyea, Daniel A., McCloskey, James K., Odenike, Olatoyosi, Löwenberg, Bob, Ossenkoppele, Gert J., Patel, Prapti A., Roshal, Mikhail, Frattini, Mark G., Lersch, Frederik, Franovic, Aleksandra, Nabhan, Salah, Fan, Bin, Choe, Sung, Wang, Hongfang, Wu, Bin, Hua, Lei, Almon, Caroline, Cooper, Michael, Kantarjian, Hagop M., Tallman, Martin S.

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Clonal diversity predicts adverse outcome in chronic lymphocytic leukemia gan Leeksma, Alexander C., Taylor, Justin, Wu, Bian, Gardner, Jeffrey R., He, Jie, Nahas, Michelle, Gonen, Mithat, Alemayehu, Wendimagegn G., te Raa, Doreen, Walther, Tatjana, Hüllein, Jennifer, Dietrich, Sascha, Claus, Rainer, de Boer, Fransien, de Heer, Koen, Dubois, Julie, Dampmann, Maria, Dürig, Jan, van Oers, Marinus H. J., Geisler, Christian H., Eldering, Eric, Levine, Ross L., Miller, Vincent, Mughal, Tariq, Lamanna, Nicole, Frattini, Mark G., Heaney, Mark L., Zelenetz, Andrew, Zenz, Thorsten, Abdel-Wahab, Omar, Kater, Arnon P.

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Isoform Switching as a Mechanism of Acquired Resistance to Mutant Isocitrate Dehydrogenase Inhibition gan Harding, James J., Lowery, Maeve A., Shih, Alan H., Schvartzman, Juan M., Hou, Shengqi, Famulare, Christopher, Patel, Minal, Roshal, Mikhail, Do, Richard K., Zehir, Ahmet, You, Daoqi, Selcuklu, S. Duygu, Viale, Agnes, Tallman, Martin S., Hyman, David M., Reznik, Ed, Finley, Lydia W.S., Papaemmanuil, Elli, Tosolini, Alessandra, Frattini, Mark G., MacBeth, Kyle J., Liu, Guowen, Fan, Bin, Choe, Sung, Wu, Bin, Janjigian, Yelena Y., Mellinghoff, Ingo K., Diaz, Luis A., Levine, Ross L., Abou-Alfa, Ghassan K., Stein, Eytan M., Intlekofer, Andrew M.

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