Výsledky vyhledávání - Francisco‐Javier Gamo

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  1. 1
    Global Phenotypic Screening for Antimalarials

    Global Phenotypic Screening for Antimalarials Autor W. Armand Guiguemde, Anang A. Shelat, José Garcia-Bustos, Thierry T. Diagana, Francisco‐Javier Gamo, R. Kiplin Guy

    Vydáno 2012
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  2. 2
    In Vitro Resistance Selections for Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors Give Mutants with Multiple Point Mutations in the Drug-binding Site and Altered Growth

    In Vitro Resistance Selections for Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors Give Mutants with Multiple Point Mutations in the Drug-binding Site and Altered Gro... Autor Leila S. Ross, Francisco‐Javier Gamo, María José Lafuente-Monasterio, Onkar Singh, Paul Rowland, Roger C. Wiegand, Dyann F. Wirth

    Vydáno 2014
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  3. 3
    P. falciparum In Vitro Killing Rates Allow to Discriminate between Different Antimalarial Mode-of-Action

    P. falciparum In Vitro Killing Rates Allow to Discriminate between Different Antimalarial Mode-of-Action Autor Laura M. Sanz, Benigno Crespo, Cristina De-Cózar, Xavier C. Ding, Jose Luis Llergo, Jeremy N. Burrows, José Garcia-Bustos, Francisco‐Javier Gamo

    Vydáno 2012
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  4. 4
    Global Transcriptional Response of <i>Bacillus subtilis</i> to Heat Shock

    Global Transcriptional Response of <i>Bacillus subtilis</i> to Heat Shock Autor John D. Helmann, Ming‐Fang Wu, Phil A. Kobel, Francisco‐Javier Gamo, Michael R. Wilson, Maud M. Morshedi, Marc Navre, Christopher J. Paddon

    Vydáno 2001
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  5. 5
    Identifying rapidly parasiticidal anti-malarial drugs using a simple and reliable in vitro parasite viability fast assay

    Identifying rapidly parasiticidal anti-malarial drugs using a simple and reliable in vitro parasite viability fast assay Autor María Linares, Sara Viera, Benigno Crespo, Virginia Franco, Marı́a G. Gómez-Lorenzo, Marı́a Belén Jiménez-Dı́az, Íñigo Angulo‐Barturen, Laura M. Sanz, Francisco‐Javier Gamo

    Vydáno 2015
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  6. 6
    Harnessing evolutionary fitness in <i>Plasmodium falciparum</i> for drug discovery and suppressing resistance

    Harnessing evolutionary fitness in <i>Plasmodium falciparum</i> for drug discovery and suppressing resistance Autor Amanda K. Lukens, Leila S. Ross, Richard W. Heidebrecht, Francisco‐Javier Gamo, María José Lafuente-Monasterio, Michael L. Booker, Daniel L. Hartl, Roger C. Wiegand, Dyann F. Wirth

    Vydáno 2013
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  7. 7
    Unravelling the mode of action of the Tres Cantos Antimalarial Set (TCAMS): investigating the mechanism of potent antimalarial compounds potentially targeting the human serotonin receptor

    Unravelling the mode of action of the Tres Cantos Antimalarial Set (TCAMS): investigating the mechanism of potent antimalarial compounds potentially targeting the human serotonin r... Autor Benedito Matheus dos Santos, Lenna Rosanie Cordero Mallaupoma, Mateus Fila Pecenin, Abhinab Mohanty, Angela Lu, Paula J. Bartlett, Andrew P. Thomas, Francisco‐Javier Gamo, Célia R. S. Garcia

    Vydáno 2025
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  8. 8
    Identification of Plasmodium falciparum Mitochondrial Malate: Quinone Oxidoreductase Inhibitors from the Pathogen Box

    Identification of Plasmodium falciparum Mitochondrial Malate: Quinone Oxidoreductase Inhibitors from the Pathogen Box Autor Xinying Wang, Yukiko Miyazaki, D.K. Inaoka, Endah Dwi Hartuti, Yoh‐ichi Watanabe, T. Shiba, Shigeharu Harada, Hiroyuki Saimoto, Jeremy N. Burrows, Francisco Javier Gamo Benito, Tomoyoshi Nozaki, Kiyoshi Kita

    Vydáno 2019
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  9. 9
    Drug Screen Targeted at Plasmodium Liver Stages Identifies a Potent Multistage Antimalarial Drug

    Drug Screen Targeted at Plasmodium Liver Stages Identifies a Potent Multistage Antimalarial Drug Autor Filipa P. da Cruz, Cécilie Martin, Kathrin Buchholz, María José Lafuente-Monasterio, Tiago Rodrigues, Birte Sönnichsen, Rui Moreira, Francisco‐Javier Gamo, Matthias Marti, Maria M. Mota, Michael Hannus, Miguel Prudêncio

    Vydáno 2012
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  10. 10
    Identification of Plasmodium falciparum Mitochondrial Malate: Quinone Oxidoreductase Inhibitors from the Pathogen Box

    Identification of Plasmodium falciparum Mitochondrial Malate: Quinone Oxidoreductase Inhibitors from the Pathogen Box Autor Wang, Xinying, Miyazaki, Yukiko, Inaoka, Daniel Ken, Hartuti, Endah Dwi, Watanabe, Yoh-Ichi, Shiba, Tomoo, Harada, Shigeharu, Saimoto, Hiroyuki, Burrows, Jeremy Nicholas, Benito, Francisco Javier Gamo, Nozaki, Tomoyoshi, Kita, Kiyoshi

    Vydáno 2019
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  11. 11
    Overexpression of plasmepsin II and plasmepsin III does not directly cause reduction in Plasmodium falciparum sensitivity to artesunate, chloroquine and piperaquine

    Overexpression of plasmepsin II and plasmepsin III does not directly cause reduction in Plasmodium falciparum sensitivity to artesunate, chloroquine and piperaquine Autor Duangkamon Loesbanluechai, Namfon Kotanan, Cristina de Cózar, Theerarat Kochakarn, Megan R. Ansbro, Kesinee Chotivanich, Nicholas J. White, Prapon Wilairat, Lee M, Francisco‐Javier Gamo, Laura M. Sanz, Thanat Chookajorn, Krittikorn Kümpornsin

    Vydáno 2018
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  12. 12
    The Parasite Reduction Ratio (PRR) Assay Version 2: Standardized Assessment of Plasmodium falciparum Viability after Antimalarial Treatment In Vitro

    The Parasite Reduction Ratio (PRR) Assay Version 2: Standardized Assessment of Plasmodium falciparum Viability after Antimalarial Treatment In Vitro Autor Annabelle Walz, Maëlle Duffey, Ghaith Aljayyoussi, Sibylle Sax, Didier Leroy, Dominique Besson, Jeremy N. Burrows, Mohammed H. Cherkaoui‐Rbati, Nathalie Gobeau, Marie-Anne Westwood, Christoph Siethoff, Francisco‐Javier Gamo, Pascal Mäser, Sergio Wittlin

    Vydáno 2023
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  13. 13
    An Invitation to Open Innovation in Malaria Drug Discovery: 47 Quality Starting Points from the TCAMS

    An Invitation to Open Innovation in Malaria Drug Discovery: 47 Quality Starting Points from the TCAMS Autor Félix Calderón, David Barros, José M. Bueno, José M. Coterón, Esther Fernández, Francisco‐Javier Gamo, José Luís Lavandera, María Luisa León, Simon J. F. Macdonald, Araceli Mallo, Pilar Manzano, Esther Porras, José M. Fiandor, Julia Castro

    Vydáno 2011
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  14. 14
    Repositioning: the fast track to new anti-malarial medicines?

    Repositioning: the fast track to new anti-malarial medicines? Autor Julie Lotharius, Francisco Javier Gamo‐Benito, Íñigo Angulo‐Barturen, Julie Clark, Michele Connelly, Santiago Ferrer, Tanya Parkinson, Pavithra Viswanath, Balachandra Bandodkar, Nikhil Rautela, Sowmya Bharath, Sandra Duffy, Vicky M. Avery, Jörg J. Möhrle, R. Kiplin Guy, Timothy N. C. Wells

    Vydáno 2014
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  15. 15
    Identification and Validation of Tetracyclic Benzothiazepines as Plasmodium falciparum Cytochrome bc1 Inhibitors

    Identification and Validation of Tetracyclic Benzothiazepines as Plasmodium falciparum Cytochrome bc1 Inhibitors Autor Carolyn K. Dong, Sameer Urgaonkar, Joseph F. Cortese, Francisco‐Javier Gamo, José Garcia-Bustos, María José Lafuente, Vishal Patel, Leila S. Ross, Bradley I. Coleman, Emily R. Derbyshire, Clary B. Clish, Adelfa E. Serrano, Mandy Cromwell, Robert H. Barker, Jeffrey D. Dvorin, Manoj T. Duraisingh, Dyann F. Wirth, Jon Clardy, Ralph Mazitschek

    Vydáno 2011
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  16. 16
    A high throughput screen for next-generation leads targeting malaria parasite transmission

    A high throughput screen for next-generation leads targeting malaria parasite transmission Autor Michael J. Delves, Celia Miguel-Blanco, Holly Matthews, Irene T. Molina‐Martínez, Andrea Ruecker, Sabrina Yahiya, Ursula Straschil, Matthew Abraham, María Luisa León, Oliver Fischer, Ainoa Rueda‐Zubiaurre, Jochen R. Brandt, Álvaro Cortés-Cabrera, Anna Barnard, Matthew J. Fuchter, Félix Calderón, Elizabeth A. Winzeler, Robert E. Sinden, Esperanza Herreros, Francisco‐Javier Gamo, Jake Baum

    Vydáno 2018
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  17. 17
    A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue

    A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue Autor Ebere Sonoiki, Caroline L. Ng, Lee M, Denghui Guo, Yong-Kang Zhang, Yasheen Zhou, M.R. Alley, Vida Ahyong, Laura M. Sanz, María José Lafuente-Monasterio, Chen Dong, Patrick G. Schupp, Jiří Gut, Jenny Legac, Roland A. Cooper, Francisco‐Javier Gamo, Joseph L. DeRisi, Yvonne R. Freund, David A. Fidock, Philip J. Rosenthal

    Vydáno 2017
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  18. 18
    Histone Methyltransferase Inhibitors Are Orally Bioavailable, Fast-Acting Molecules with Activity against Different Species Causing Malaria in Humans

    Histone Methyltransferase Inhibitors Are Orally Bioavailable, Fast-Acting Molecules with Activity against Different Species Causing Malaria in Humans Autor Nicholas A. Malmquist, Sandeep Sundriyal, Joachim Caron, Patty Chen, Benoît Witkowski, Didier Ménard, Rossarin Suwanarusk, Laurent Rénia, François Nosten, Marı́a Belén Jiménez-Dı́az, Íñigo Angulo‐Barturen, María Santos Martínez, Santiago Ferrer, Laura M. Sanz, Francisco‐Javier Gamo, Sergio Wittlin, Sandra Duffy, Vicky M. Avery, Andrea Ruecker, Michael J. Delves, Robert E. Sinden, Matthew J. Fuchter, Artur Scherf

    Vydáno 2014
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  19. 19
    MalDA, Accelerating Malaria Drug Discovery

    MalDA, Accelerating Malaria Drug Discovery Autor Tuo Yang, Sabine Ottilie, Eva S. Istvan, Karla P. Godinez‐Macias, Amanda K. Lukens, Beatriz Baragaña, Brice Campo, Chris Walpole, Jacquin C. Niles, Kelly Chibale, Koen J. Dechering, Manuel Llinás, Lee M, Nobutaka Kato, Susan Wyllie, Case W. McNamara, Francisco‐Javier Gamo, Jeremy N. Burrows, David A. Fidock, Daniel E. Goldberg, Ian H. Gilbert, Dyann F. Wirth, Elizabeth A. Winzeler

    Vydáno 2021
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  20. 20
    Generation of a mutator parasite to drive resistome discovery in Plasmodium falciparum

    Generation of a mutator parasite to drive resistome discovery in Plasmodium falciparum Autor Krittikorn Kümpornsin, Theerarat Kochakarn, Tomas Yeo, John Okombo, Madeline R. Luth, Johanna Hoshizaki, Mukul Rawat, Richard D. Pearson, Kyra A. Schindler, Sachel Mok, Heekuk Park, Anne‐Catrin Uhlemann, Gouranga P. Jana, Bikash C. Maity, Benoı̂t Laleu, Elodie Chenu, James Duffy, Sonia Moliner Cubel, Virginia Franco, Marı́a G. Gómez-Lorenzo, Francisco‐Javier Gamo, Elizabeth A. Winzeler, David A. Fidock, Thanat Chookajorn, Lee M

    Vydáno 2023
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