Kết quả tìm kiếm - Francesc X. Ruiz

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  1. 1
    Evolving understanding of HIV-1 reverse transcriptase structure, function, inhibition, and resistance

    Evolving understanding of HIV-1 reverse transcriptase structure, function, inhibition, and resistance Bằng Francesc X. Ruiz, Eddy Arnold

    Được phát hành 2020
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    Revisão
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  2. 2
    Biological Role of Aldo–Keto Reductases in Retinoic Acid Biosynthesis and Signaling

    Biological Role of Aldo–Keto Reductases in Retinoic Acid Biosynthesis and Signaling Bằng Francesc X. Ruiz, Sergio Porté, Xavier Parés, Jaume Farrés

    Được phát hành 2012
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    Artigo
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  3. 3
    X-Ray Crystal Structure of the Full Length Human Chitotriosidase (CHIT1) Reveals Features of Its Chitin Binding Domain

    X-Ray Crystal Structure of the Full Length Human Chitotriosidase (CHIT1) Reveals Features of Its Chitin Binding Domain Bằng Firas Fadel, Yuguang Zhao, A. Cousido-Siah, Francesc X. Ruiz, A. Mitschler, A. Podjarny

    Được phát hành 2016
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    Artigo
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  4. 4
    Structural basis for the high <i>all-trans</i> -retinaldehyde reductase activity of the tumor marker AKR1B10

    Structural basis for the high <i>all-trans</i> -retinaldehyde reductase activity of the tumor marker AKR1B10 Bằng Oriol Gallego, Francesc X. Ruiz, Albert Ardèvol, Marta Domínguez, Rosana Álvarez, Ángel R. de Lera, Carme Rovira, Jaume Farrés, Ignacio Fita, Xavier Parés

    Được phát hành 2007
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    Artigo
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  5. 5
    Comparative functional analysis of human medium-chain dehydrogenases, short-chain dehydrogenases/reductases and aldo-keto reductases with retinoids

    Comparative functional analysis of human medium-chain dehydrogenases, short-chain dehydrogenases/reductases and aldo-keto reductases with retinoids Bằng Oriol Gallego, Olga V. Belyaeva, Sergio Porté, Francesc X. Ruiz, Anton V. Stetsenko, Elena Shabrova, Natalia V. Kostereva, Jaume Farrés, Xavier Parés, Natalia Y. Kedishvili

    Được phát hành 2006
    lấy văn bản
    Artigo
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  6. 6
    Design of quinoline SARS-CoV-2 papain-like protease inhibitors as oral antiviral drug candidates

    Design of quinoline SARS-CoV-2 papain-like protease inhibitors as oral antiviral drug candidates Bằng Prakash D. Jadhav, Xueying Liang, Ahmadullah Ansari, Bin Tan, Haozhou Tan, Kan Li, Xiang Chi, Alexandra K. Ford, Francesc X. Ruiz, Eddy Arnold, Xufang Deng, Jun Wang

    Được phát hành 2025
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    Artigo
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  7. 7
    Design of a SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model

    Design of a SARS-CoV-2 papain-like protease inhibitor with antiviral efficacy in a mouse model Bằng Bin Tan, Xiaoming Zhang, Ahmadullah Ansari, Prakash D. Jadhav, Haozhou Tan, Kan Li, Ashima Chopra, Alexandra Ford, Xiang Chi, Francesc X. Ruiz, Eddy Arnold, Xufang Deng, Jun Wang

    Được phát hành 2024
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    Artigo
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  8. 8
    Development of enhanced HIV-1 non-nucleoside reverse transcriptase inhibitors with improved resistance and pharmacokinetic profiles

    Development of enhanced HIV-1 non-nucleoside reverse transcriptase inhibitors with improved resistance and pharmacokinetic profiles Bằng Zhao Wang, Shawn Rumrill, Dongwei Kang, Samuel Desta Guma, Da Feng, Erik De Clercq, Christophe Pannecouque, Chin‐Ho Chen, Eddy Arnold, Francesc X. Ruiz, Xinyong Liu, Peng Zhan

    Được phát hành 2025
    lấy văn bản
    Artigo
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  9. 9
    Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53

    Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53 Bằng Denise Martinez-Zapien, Francesc X. Ruiz, Juline Poirson, A. Mitschler, Juan Antonio Ortega, Anne Förster, A. Cousido-Siah, Murielle Masson, Scott Vande Pol, A. Podjarny, Gilles Travé, Katia Zanier

    Được phát hành 2016
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    Artigo
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  10. 10
    Discovery and Characterization of Fluorine-Substituted Diarylpyrimidine Derivatives as Novel HIV-1 NNRTIs with Highly Improved Resistance Profiles and Low Activity for the hERG Ion Channel

    Discovery and Characterization of Fluorine-Substituted Diarylpyrimidine Derivatives as Novel HIV-1 NNRTIs with Highly Improved Resistance Profiles and Low Activity for the hERG Ion... Bằng Dongwei Kang, Francesc X. Ruiz, Da Feng, Alyssa Pilch, Tong Zhao, Fenju Wei, Zhao Wang, Yanying Sun, Zengjun Fang, Erik De Clercq, Christophe Pannecouque, Eddy Arnold, Xinyong Liu, Peng Zhan

    Được phát hành 2020
    lấy văn bản
    Artigo
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  11. 11
    Discovery of diarylpyrimidine derivatives bearing piperazine sulfonyl as potent HIV-1 nonnucleoside reverse transcriptase inhibitors

    Discovery of diarylpyrimidine derivatives bearing piperazine sulfonyl as potent HIV-1 nonnucleoside reverse transcriptase inhibitors Bằng Xiangyi Jiang, Boshi Huang, Shawn Rumrill, David Pople, Waleed A. Zalloum, Dongwei Kang, Fabao Zhao, Xiangkai Ji, Zhen Gao, Lide Hu, Zhao Wang, Minghui Xie, Erik De Clercq, Francesc X. Ruiz, Eddy Arnold, Christophe Pannecouque, Xinyong Liu, Peng Zhan

    Được phát hành 2023
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    Artigo
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  12. 12
    Discovery of (<i>R</i>)-2-Amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic Acid and Congeners As Highly Potent Inhibitors of Human Arginases I and II for Treatment of Myocardial Reperfusion Injury

    Discovery of (<i>R</i>)-2-Amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic Acid and Congeners As Highly Potent Inhibitors of Human Arginases I and II for Treatment of Myocardial... Bằng M.C. Van Zandt, Darren L. Whitehouse, Adam Gołȩbiowski, Min Koo Ji, Mingbao Zhang, R. Paul Beckett, G. Erik Jagdmann, Todd R. Ryder, Ryan Sheeler, Monica Andreoli, Barbara R. Conway, Keyvan Mahboubi, Gerard D’Angelo, A. Mitschler, A. Cousido-Siah, Francesc X. Ruiz, Eduardo Howard, A. Podjarny, Hagen Schroeter

    Được phát hành 2013
    lấy văn bản
    Artigo
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  13. 13
    Evolution of the <scp>SARS‐CoV</scp>‐2 proteome in three dimensions (3D) during the first 6 months of the <scp>COVID</scp>‐19 pandemic

    Evolution of the <scp>SARS‐CoV</scp>‐2 proteome in three dimensions (3D) during the first 6 months of the <scp>COVID</scp>‐19 pandemic Bằng Joseph H. Lubin, Christine Zardecki, Elliott M. Dolan, Changpeng Lu, Zhuofan Shen, Shuchismita Dutta, John D. Westbrook, Brian P. Hudson, David S. Goodsell, Jonathan K. Williams, Maria Voigt, Vidur Sarma, Lingjun Xie, Thejasvi Venkatachalam, Steven E. Arnold, Luz Helena Alfaro Alvarado, Kevin Catalfano, Aaliyah Khan, Erika McCarthy, Sophia Staggers, Brea Tinsley, Alan Trudeau, Jitendra Singh, Lindsey Whitmore, Helen Zheng, Matthew Benedek, Jenna Currier, Mark Dresel, Ashish Duvvuru, Britney Dyszel, Emily Fingar, Elizabeth M. Hennen, Michael Kirsch, Ali A. Khan, Charlotte Labrie‐Cleary, Stephanie Laporte, Evan Lenkeit, Kailey N. Martin, Marilyn Orellana, Melanie Ortiz Alvarez de la Campa, Isaac Paredes, Baleigh Wheeler, Allison Rupert, Andrew Sam, Katherine See, Santiago Soto Zapata, P. Craig, Bonnie L. Hall, Jennifer Jiang, Julia R. Koeppe, Stephen A. Mills, Michael J. Pikaart, Rebecca Roberts, Yana Bromberg, J. Steen Hoyer, Siobain Duffy, Jay A. Tischfield, Francesc X. Ruiz, Eddy Arnold, Jean Baum, Jesse Sandberg, Grace Brannigan, Sagar D. Khare, S.K. Burley

    Được phát hành 2021
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    Artigo
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