Resultats de la cerca - Françoise Debart

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  1. 1
    La-related protein 1 (LARP1) repression of TOP mRNA translation is mediated through its cap-binding domain and controlled by an adjacent regulatory region

    La-related protein 1 (LARP1) repression of TOP mRNA translation is mediated through its cap-binding domain and controlled by an adjacent regulatory region per Lucas Philippe, Jean‐Jacques Vasseur, Françoise Debart, Carson C. Thoreen

    Publicat 2017
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  2. 2
    Efficient Solid-Phase Chemical Synthesis of 5′-Triphosphates of DNA, RNA, and their Analogues

    Efficient Solid-Phase Chemical Synthesis of 5′-Triphosphates of DNA, RNA, and their Analogues per Ivan Zlatev, Thomas Lavergne, Françoise Debart, Jean‐Jacques Vasseur, Muthiah Manoharan, F. Morvan

    Publicat 2010
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  3. 3
    Synthesis of 5′ cap-0 and cap-1 RNAs using solid-phase chemistry coupled with enzymatic methylation by human (guanine-<i>N</i><sup>7</sup>)-methyl transferase

    Synthesis of 5′ cap-0 and cap-1 RNAs using solid-phase chemistry coupled with enzymatic methylation by human (guanine-<i>N</i><sup>7</sup>)-methyl transferase per Yann Thillier, Étienne Decroly, F. Morvan, Bruno Canard, Jean‐Jacques Vasseur, Françoise Debart

    Publicat 2012
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  4. 4
    Binding of the Methyl Donor<i>S</i>-Adenosyl-<scp>l</scp>-Methionine to Middle East Respiratory Syndrome Coronavirus 2′-<i>O</i>-Methyltransferase nsp16 Promotes Recruitment of the Allosteric Activator nsp10

    Binding of the Methyl Donor<i>S</i>-Adenosyl-<scp>l</scp>-Methionine to Middle East Respiratory Syndrome Coronavirus 2′-<i>O</i>-Methyltransferase nsp16 Promotes Recruitment of the... per Wahiba Aouadi, Alexandre Blanjoie, Jean‐Jacques Vasseur, Françoise Debart, Bruno Canard, Étienne Decroly

    Publicat 2016
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  5. 5
    Cap-proximal nucleotides via differential eIF4E binding and alternative promoter usage mediate translational response to energy stress

    Cap-proximal nucleotides via differential eIF4E binding and alternative promoter usage mediate translational response to energy stress per Ana Tamarkin-Ben-Harush, Jean‐Jacques Vasseur, Françoise Debart, Igor Ulitsky, Rivka Dikstein

    Publicat 2017
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  6. 6
    Synthesis of adenine dinucleosides SAM analogs as specific inhibitors of SARS-CoV nsp14 RNA cap guanine-N7-methyltransferase

    Synthesis of adenine dinucleosides SAM analogs as specific inhibitors of SARS-CoV nsp14 RNA cap guanine-N7-methyltransferase per Rostom Ahmed‐Belkacem, Priscila Sutto‐Ortiz, Mathis Guiraud, Bruno Canard, Jean‐Jacques Vasseur, Étienne Decroly, Françoise Debart

    Publicat 2020
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  7. 7
    mRNA Capping by Venezuelan Equine Encephalitis Virus nsP1: Functional Characterization and Implications for Antiviral Research

    mRNA Capping by Venezuelan Equine Encephalitis Virus nsP1: Functional Characterization and Implications for Antiviral Research per Changqing Li, Jaime Guillén, Nadia Rabah, Alexandre Blanjoie, Françoise Debart, Jean‐Jacques Vasseur, Bruno Canard, Étienne Decroly, Bruno Coutard

    Publicat 2015
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  8. 8
    X-ray structure and activities of an essential Mononegavirales L-protein domain

    X-ray structure and activities of an essential Mononegavirales L-protein domain per Guido C. Paesen, Axelle Collet, Corinne Sallamand, Françoise Debart, Jean‐Jacques Vasseur, Bruno Canard, Étienne Decroly, Jonathan M. Grimes

    Publicat 2015
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  9. 9
    Molecular Basis for Nucleotide Conservation at the Ends of the Dengue Virus Genome

    Molecular Basis for Nucleotide Conservation at the Ends of the Dengue Virus Genome per Barbara Selisko, Supanee Potisopon, Rym Agred, Stéphane Priet, Isabelle Varlet, Yann Thillier, Corinne Sallamand, Françoise Debart, Jean‐Jacques Vasseur, Bruno Canard

    Publicat 2012
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  10. 10
    The methyltransferase domain of the Sudan ebolavirus L protein specifically targets internal adenosines of RNA substrates, in addition to the cap structure

    The methyltransferase domain of the Sudan ebolavirus L protein specifically targets internal adenosines of RNA substrates, in addition to the cap structure per Baptiste Martin, Bruno Coutard, Théo Guez, Guido C. Paesen, Bruno Canard, Françoise Debart, Jean‐Jacques Vasseur, Jonathan M. Grimes, Étienne Decroly

    Publicat 2018
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  11. 11
    Zika Virus Methyltransferase: Structure and Functions for Drug Design Perspectives

    Zika Virus Methyltransferase: Structure and Functions for Drug Design Perspectives per Bruno Coutard, Karine Barral, Julie Lichière, Barbara Selisko, Baptiste Martin, Wahiba Aouadi, Miguel Ortiz Lombardía, Françoise Debart, Jean‐Jacques Vasseur, Jean Claude Guillemot, Bruno Canard, Étienne Decroly

    Publicat 2016
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  12. 12
    FTO controls reversible m6Am RNA methylation during snRNA biogenesis

    FTO controls reversible m6Am RNA methylation during snRNA biogenesis per Jan Mauer, Miriam Sindelar, Vladimir Despic, Théo Guez, Ben R Hawley, Jean‐Jacques Vasseur, Andrea Rentmeister, Steven S. Gross, Livio Pellizzoni, Françoise Debart, Hani Goodarzi, Samie R. Jaffrey

    Publicat 2019
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  13. 13
    Toward the identification of viral cap-methyltransferase inhibitors by fluorescence screening assay

    Toward the identification of viral cap-methyltransferase inhibitors by fluorescence screening assay per Wahiba Aouadi, Cécilia Eydoux, Bruno Coutard, Baptiste Martin, Françoise Debart, Jean‐Jacques Vasseur, Jean Contreras, Christophe Morice, Gilles Quérat, Marie‐Louise Jung, Bruno Canard, Jean‐Claude Guillemot, Étienne Decroly

    Publicat 2017
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  14. 14
    Identification of the m6Am Methyltransferase PCIF1 Reveals the Location and Functions of m6Am in the Transcriptome

    Identification of the m6Am Methyltransferase PCIF1 Reveals the Location and Functions of m6Am in the Transcriptome per Konstantinos Boulias, Diana Toczydłowska-Socha, Ben R Hawley, Noa Liberman, Ken Takashima, Sara Zaccara, Théo Guez, Jean‐Jacques Vasseur, Françoise Debart, L. Aravind, Samie R. Jaffrey, Eric Lieberman Greer

    Publicat 2019
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  15. 15
    Potent Inhibition of SARS-CoV-2 nsp14 <i>N</i>7-Methyltransferase by Sulfonamide-Based Bisubstrate Analogues

    Potent Inhibition of SARS-CoV-2 nsp14 <i>N</i>7-Methyltransferase by Sulfonamide-Based Bisubstrate Analogues per Rostom Ahmed‐Belkacem, Marcel Hausdorff, Adrien Delpal, Priscila Sutto‐Ortiz, Agathe M. G. Colmant, Franck Touret, Natacha S. Ogando, Eric J. Snijder, Bruno Canard, Bruno Coutard, Jean‐Jacques Vasseur, Étienne Decroly, Françoise Debart

    Publicat 2022
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  16. 16
    Reversible methylation of m6Am in the 5′ cap controls mRNA stability

    Reversible methylation of m6Am in the 5′ cap controls mRNA stability per Jan Mauer, Xiaobing Luo, Alexandre Blanjoie, Xinfu Jiao, Anya V. Grozhik, Deepak P. Patil, Bastian Linder, Brian F. Pickering, Jean‐Jacques Vasseur, Qiuying Chen, Steven S. Gross, Olivier Elemento, Françoise Debart, Megerditch Kiledjian, Samie R. Jaffrey

    Publicat 2016
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  17. 17
    FTO-mediated cytoplasmic m6Am demethylation adjusts stem-like properties in colorectal cancer cell

    FTO-mediated cytoplasmic m6Am demethylation adjusts stem-like properties in colorectal cancer cell per Sébastien Relier, Julie Ripoll, Hélène Guillorit, Amandine Amalric, Cyrinne Achour, Florence Boissière‐Michot, Jérôme Vialaret, Aurore Attina, Françoise Debart, Armelle Choquet, Françoise Macari, Virginie Marchand, Yuri Motorin, Emmanuelle Samalin, Jean‐Jacques Vasseur, Julie Pannequin, Francesca Aguiló, Evelyne Lopez‐Crapez, Christophe Hirtz, Éric Rivals, Amandine Bastide, Alexandre David

    Publicat 2021
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  18. 18
    AT-752 targets multiple sites and activities on the Dengue virus replication enzyme NS5

    AT-752 targets multiple sites and activities on the Dengue virus replication enzyme NS5 per Mikaël Feracci, Cécilia Eydoux, Véronique Fattorini, Léa Lo Bello, Pierre Gauffre, Barbara Selisko, Priscila Sutto‐Ortiz, Ashleigh Shannon, Hongjie Xia, Pei‐Yong Shi, Mathieu Noël, Françoise Debart, Jean‐Jacques Vasseur, Steven S. Good, Kai Lin, Adel Moussa, Jean‐Pierre Sommadossi, Aurélie Chazot, Karine Alvarez, Jean‐Claude Guillemot, Étienne Decroly, François Ferrón, Bruno Canard

    Publicat 2023
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