Search Results - Fonnet E. Bleeker

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  1. 1
    Recent advances in the molecular understanding of glioblastoma

    Recent advances in the molecular understanding of glioblastoma by Fonnet E. Bleeker, Remco J. Molenaar, Sieger Leenstra

    Published 2012
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  2. 2
    Novel Somatic and Germline Mutations in Cancer Candidate Genes in Glioblastoma, Melanoma, and Pancreatic Carcinoma

    Novel Somatic and Germline Mutations in Cancer Candidate Genes in Glioblastoma, Melanoma, and Pancreatic Carcinoma by Asha Balakrishnan, Fonnet E. Bleeker, Simona Lamba, Monica Rodolfo, Maria Daniotti, Aldo Scarpa, Angela A. van Tilborg, Sieger Leenstra, Carlo Zanon, Alberto Bardelli

    Published 2007
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  3. 3
    Mutational Profile of GNAQQ209 in Human Tumors

    Mutational Profile of GNAQQ209 in Human Tumors by Simona Lamba, Lara Felicioni, Fiamma Buttitta, Fonnet E. Bleeker, Sara Malatesta, Vincenzo Corbo, Aldo Scarpa, Monica Rodolfo, Margaret A. Knowles, Milo Frattini, Antonio Marchetti, Alberto Bardelli

    Published 2009
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  4. 4
    The prognostic IDH1 R132 mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma

    The prognostic IDH1 R132 mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma by Fonnet E. Bleeker, Nadia A. Atai, Simona Lamba, Ard Jonker, Denise Rijkeboer, Klazien S. Bosch, Wikky Tigchelaar, Dirk Troost, W. Peter Vandertop, Alberto Bardelli, Cornelis J.F. Van Noorden

    Published 2010
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  5. 5
    Mutational profiling of kinases in glioblastoma

    Mutational profiling of kinases in glioblastoma by Fonnet E. Bleeker, Simona Lamba, Carlo Zanon, Remco J. Molenaar, Theo J.M. Hulsebos, Dirk Troost, Angela A. van Tilborg, W. Peter Vandertop, Sieger Leenstra, Cornelis J.F. Van Noorden, Alberto Bardelli

    Published 2014
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  6. 6
    Comparative Localization of Cathepsin B Protein and Activity in Colorectal Cancer

    Comparative Localization of Cathepsin B Protein and Activity in Colorectal Cancer by Lonny G. M. Hazen, Fonnet E. Bleeker, B. Lauritzen, Sieglinde Bahns, Ji‐Ying Song, Ard Jonker, Bernard E. M. Van Driel, Hans Lyon, Ulla Hansen, Angela Köhler, Cornelis J.F. Van Noorden

    Published 2000
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  7. 7
    Significance of complete 1p/19q co-deletion, IDH1 mutation and MGMT promoter methylation in gliomas: use with caution

    Significance of complete 1p/19q co-deletion, IDH1 mutation and MGMT promoter methylation in gliomas: use with caution by Sandra Boots‐Sprenger, Angelique Sijben, Jos Rijntjes, Bastiaan B.J. Tops, Albert J. S. Idema, Andreana L. Rivera, Fonnet E. Bleeker, Anja Gijtenbeek, Kristin Diefes, Lindsey Heathcock, Kenneth Aldape, Judith W. M. Jeuken, Pieter Wesseling

    Published 2013
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  8. 8
    <i>IDH1/2</i> Mutations Sensitize Acute Myeloid Leukemia to PARP Inhibition and This Is Reversed by IDH1/2-Mutant Inhibitors

    <i>IDH1/2</i> Mutations Sensitize Acute Myeloid Leukemia to PARP Inhibition and This Is Reversed by IDH1/2-Mutant Inhibitors by Remco J. Molenaar, Tomas Radivoyevitch, Yasunobu Nagata, Mohammed Khurshed, Bartolomiej Przychodzen, Hideki Makishima, Mingjiang Xu, Fonnet E. Bleeker, Johanna W. Wilmink, Hetty E. Carraway, Sudipto Mukherjee, Mikkael A. Sekeres, Cornelis J.F. Van Noorden, Jaroslaw P. Maciejewski

    Published 2018
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  9. 9
    <i>IDH1</i>mutations at residue p.R132 (IDH1<sup>R132</sup>) occur frequently in high-grade gliomas but not in other solid tumors

    <i>IDH1</i>mutations at residue p.R132 (IDH1<sup>R132</sup>) occur frequently in high-grade gliomas but not in other solid tumors by Fonnet E. Bleeker, Simona Lamba, Sieger Leenstra, Dirk Troost, Theo J.M. Hulsebos, W. Peter Vandertop, Milo Frattini, Francesca Molinari, Margaret A. Knowles, Aniello Cerrato, Monica Rodolfo, Aldo Scarpa, Lara Felicioni, Fiamma Buttitta, Sara Malatesta, Antonio Marchetti, Alberto Bardelli

    Published 2009
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  10. 10
    The combination of IDH1 mutations and MGMT methylation status predicts survival in glioblastoma better than either IDH1 or MGMT alone

    The combination of IDH1 mutations and MGMT methylation status predicts survival in glioblastoma better than either IDH1 or MGMT alone by Remco J. Molenaar, Dagmar Verbaan, Simona Lamba, Carlo Zanon, Judith W. M. Jeuken, Sandra Boots‐Sprenger, Pieter Wesseling, Theo J.M. Hulsebos, Dirk Troost, Angela A. van Tilborg, Sieger Leenstra, W. Peter Vandertop, Alberto Bardelli, Cornelis J.F. Van Noorden, Fonnet E. Bleeker

    Published 2014
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  11. 11
    Segregation of non-p.R132H mutations in<i>IDH1</i>in distinct molecular subtypes of glioma

    Segregation of non-p.R132H mutations in<i>IDH1</i>in distinct molecular subtypes of glioma by Lonneke A.M. Gravendeel, Nanne K. Kloosterhof, Linda B.C. Bralten, Ronald van Marion, Hendrikus J. Dubbink, Winand N.M. Dinjens, Fonnet E. Bleeker, Casper C. Hoogenraad, Erna Michiels, Johan M. Kros, Martin J. van den Bent, Peter A.E. Sillevis Smitt, Pim J. French

    Published 2010
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  12. 12
    Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer

    Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer by Ludovic Barault, Alessio Amatu, Fonnet E. Bleeker, Cátia Moutinho, Chiara Falcomatà, Valentina Fiano, Andrea Cassingena, Giulia Siravegna, Massimo Milione, Paola Cassoni, Filippo de Braud, Roberta Rudà, Riccardo Soffietti, Tiziana Venesio, Alberto Bardelli, Pieter Wesseling, Philip C. De Witt Hamer, Filippo Pietrantonio, Salvatore Siena, Manel Esteller, Andrea Sartore‐Bianchi, Federica Di Nicolantonio

    Published 2015
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  13. 13
    Clinical and biological implications of ancestral and non-ancestral IDH1 and IDH2 mutations in myeloid neoplasms

    Clinical and biological implications of ancestral and non-ancestral IDH1 and IDH2 mutations in myeloid neoplasms by Remco J. Molenaar, Swapna Thota, Yasunobu Nagata, Bhumika J. Patel, Michael J. Clemente, Bartlomiej Przychodzen, Cassandra Hirsh, Aaron D. Viny, N Hosano, Fonnet E. Bleeker, Manja Meggendorfer, Tamara Alpermann, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Cornelis J.F. Van Noorden, Tomas Radivoyevitch, Hetty E. Carraway, Hideki Makishima, Satoru Miyano, Mikkael A. Sekeres, Seishi Ogawa, Torsten Haferlach, Jaroslaw P. Maciejewski

    Published 2015
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  14. 14
    Intrinsic Gene Expression Profiles of Gliomas Are a Better Predictor of Survival than Histology

    Intrinsic Gene Expression Profiles of Gliomas Are a Better Predictor of Survival than Histology by Lonneke A.M. Gravendeel, Mathilde C.M. Kouwenhoven, Olivier Gevaert, Johan J. de Rooi, Andrew Stubbs, J. Elza Duijm, Anneleen Daemen, Fonnet E. Bleeker, Linda B.C. Bralten, Nanne K. Kloosterhof, Bart De Moor, Paul H.C. Eilers, Peter J. van der Spek, Johan M. Kros, Peter A.E. Sillevis Smitt, Martin J. van den Bent, Pim J. French

    Published 2009
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  15. 15
    Radioprotection of <i>IDH1</i>-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198

    Radioprotection of <i>IDH1</i>-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198 by Remco J. Molenaar, Dennis Botman, Myrthe A J Smits, Vashendriya V.V. Hira, Sanne A. M. van Lith, Jan Stap, Peter Henneman, Mohammed Khurshed, Krissie Lenting, Adri N. Mul, Dionysia Dimitrakopoulou, Cornelis M. van Drunen, Ron A. Hoebe, Tomas Radivoyevitch, Johanna W. Wilmink, Jaroslaw P. Maciejewski, W. Peter Vandertop, William P. J. Leenders, Fonnet E. Bleeker, Cornelis J.F. Van Noorden

    Published 2015
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  16. 16
    Families with BAP1-Tumor Predisposition Syndrome in The Netherlands: Path to Identification and a Proposal for Genetic Screening Guidelines

    Families with BAP1-Tumor Predisposition Syndrome in The Netherlands: Path to Identification and a Proposal for Genetic Screening Guidelines by Cindy Chau, Remco van Doorn, Natasha M. van Poppelen, Nienke van der Stoep, Arjen R. Mensenkamp, Rolf H. Sijmons, Barbara W. van Paassen, Ans M.W. van den Ouweland, Nicole C. Naus, Annemieke H. van der Hout, Thomas P. Potjer, Fonnet E. Bleeker, Marijke R. Wevers, Liselotte P. van Hest, Marjolijn C.J. Jongmans, Marina Marinkovic, Jaco C. Bleeker, Martine J. Jager, Gregorius P. M. Luyten, Maartje Nielsen

    Published 2019
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