Resultados da pesquisa - Flávio da Silva Emery

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  1. 1
    Forging a Future Free from Neglected Tropical Diseases

    Forging a Future Free from Neglected Tropical Diseases Por Flávio da Silva Emery, Kelly Chibale

    Publicado em 2024
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    Editorial
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  2. 2
    Strategies towards expansion of chemical space of natural product-based compounds to enable drug discovery

    Strategies towards expansion of chemical space of natural product-based compounds to enable drug discovery Por Daniel Gedder Silva, Flávio da Silva Emery

    Publicado em 2018
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  3. 3
    CRAFT (CENTER FOR THE RESEARCH AND ADVANCEMENT IN FRAGMENTS AND MOLECULAR TARGETS) : A BRAZILIAN CENTER FOR DRUG DISCOVERY

    CRAFT (CENTER FOR THE RESEARCH AND ADVANCEMENT IN FRAGMENTS AND MOLECULAR TARGETS) : A BRAZILIAN CENTER FOR DRUG DISCOVERY Por Maria Cristina Nonato, Flávio da Silva Emery, Carolina Horta Andrade

    Publicado em 2025
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  4. 4
    Fragment screening as a tool for the search of human dihydroorotate dehydrogenase inhibitors

    Fragment screening as a tool for the search of human dihydroorotate dehydrogenase inhibitors Por Maria Cristina Nonato, Aline Dias da Purificação, Bruna Fleck Godoi, Thaís Rosa dos Santos, Flávio da Silva Emery

    Publicado em 2023
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  5. 5
    Decitabine Promotes Modulation in Phenotype and Function of Monocytes and Macrophages That Drive Immune Response Regulation

    Decitabine Promotes Modulation in Phenotype and Function of Monocytes and Macrophages That Drive Immune Response Regulation Por Fabiana Albani Zambuzi, Priscilla Mariane Cardoso-Silva, Ricardo Cardoso Castro, Caroline Fontanari, Flávio da Silva Emery, Fabiani Gai Frantz

    Publicado em 2021
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  6. 6
    Structural basis for the function and inhibition of dihydroorotate dehydrogenase from <i>Schistosoma mansoni</i>

    Structural basis for the function and inhibition of dihydroorotate dehydrogenase from <i>Schistosoma mansoni</i> Por Renan M. Mori, Mariana A. Ajalla Aleixo, Luana Carlos Campisano Zapata, Felipe A. Calil, Flávio da Silva Emery, Maria Cristina Nonato

    Publicado em 2020
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  7. 7
    Crystallographic Structure of Human Dihydroorotate Dehydrogenase in Complex with the Natural Product Inhibitor Lapachol

    Crystallographic Structure of Human Dihydroorotate Dehydrogenase in Complex with the Natural Product Inhibitor Lapachol Por Aline Dias da Purificação, L.S. Benz, Wemenes J. Lima Silva, Flávio da Silva Emery, Carolina Horta Andrade, M.S. Weiss, Maria Cristina Nonato

    Publicado em 2025
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  8. 8
    Chemoselective oxidation of benzophenazines by m-CPBA: n-oxidation vs. oxidative cleavage

    Chemoselective oxidation of benzophenazines by m-CPBA: n-oxidation vs. oxidative cleavage Por Raphael S. F. Silva, Mauro Barbosa de Amorim, Maria do Carmo F. R. Pinto, Flávio da Silva Emery, Marília Oliveira Fonseca Goulart, António Pinto

    Publicado em 2007
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  9. 9
    Cytotoxicity, hemolysis and in vivo acute toxicity of 2-hydroxy-3-anilino-1,4-naphthoquinone derivatives

    Cytotoxicity, hemolysis and in vivo acute toxicity of 2-hydroxy-3-anilino-1,4-naphthoquinone derivatives Por Valeska Santana de Sena Pereira, Cláudio Bruno Silva de Oliveira, Fernando Fumagalli, Flávio da Silva Emery, Naisandra Bezerra da Silva, Valter Ferreira de Andrade‐Neto

    Publicado em 2016
    Obter o texto integral
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  10. 10
    Fluorescent Symmetric Phenazines from Naphthoquinones

    Fluorescent Symmetric Phenazines from Naphthoquinones Por António Pinto, Cleverson N. Pinto, Maria do Carmo F. R. Pinto, Flávio da Silva Emery, Kelly C. G. de Moura, C.E.M. Carvalho, Ira M. Brinn

    Publicado em 1997
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  11. 11
    Fluorescent Symmetric Phenazines from the Reactions of β-Lapachone and Nor-β-lapachone with Ammoniating Agents

    Fluorescent Symmetric Phenazines from the Reactions of β-Lapachone and Nor-β-lapachone with Ammoniating Agents Por António Pinto, Cleverson N. Pinto, Maria do Carmo F. R. Pinto, Flávio da Silva Emery, Kelly C. G. de Moura, C.E.M. Carvalho, Ira M. Brinn

    Publicado em 1999
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  12. 12
    Trypanocidal activity of isolated naphthoquinones from Tabebuia and some heterocyclic derivatives: a review from an interdisciplinary study

    Trypanocidal activity of isolated naphthoquinones from Tabebuia and some heterocyclic derivatives: a review from an interdisciplinary study Por Kelly C. G. de Moura, Flávio da Silva Emery, Cleverson Neves‐Pinto, Maria do Carmo F. R. Pinto, Andrea P. Dantas, Kelly Salomão, Solange L. de Castro, António Pinto

    Publicado em 2001
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    Revisão
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  13. 13
    Synthesis and Structure−Activity Relationships of Imidazopyridine/Pyrimidine‐ and Furopyridine‐Based Anti‐infective Agents against Trypanosomiases

    Synthesis and Structure−Activity Relationships of Imidazopyridine/Pyrimidine‐ and Furopyridine‐Based Anti‐infective Agents against Trypanosomiases Por Daniel Gedder Silva, Anna Junker, Shaiani Maria Gil de Melo, Fernando Fumagalli, J. Robert Gillespie, Nora M. R. Molasky, Frederick S. Buckner, An Matheeussen, Guy Caljon, Louis Maes, Flávio da Silva Emery

    Publicado em 2020
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  14. 14
    Front Cover: Synthesis and Structure−Activity Relationships of Imidazopyridine/Pyrimidine‐ and Furopyridine‐Based Anti‐infective Agents against Trypanosomiases (6/2021)

    Front Cover: Synthesis and Structure−Activity Relationships of Imidazopyridine/Pyrimidine‐ and Furopyridine‐Based Anti‐infective Agents against Trypanosomiases (6/2021) Por Daniel Gedder Silva, Anna Junker, Shaiani Maria Gil de Melo, Fernando Fumagalli, J. Robert Gillespie, Nora M. R. Molasky, Frederick S. Buckner, An Matheeussen, Guy Caljon, Louis Maes, Flávio da Silva Emery

    Publicado em 2021
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    Paratexto
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  15. 15
    In vitro antiplasmodial activity, pharmacokinetic profiles and interference in isoprenoid pathway of 2-aniline-3-hydroxy-1.4-naphthoquinone derivatives

    In vitro antiplasmodial activity, pharmacokinetic profiles and interference in isoprenoid pathway of 2-aniline-3-hydroxy-1.4-naphthoquinone derivatives Por Valeska Santana de Sena Pereira, Flávio da Silva Emery, Lis Lobo, Fátima Nogueira, Jonas Ivan Nobre Oliveira, U. L. Fulco, E.L. Albuquerque, Alejandro M. Katzin, Valter Ferreira de Andrade‐Neto

    Publicado em 2018
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  16. 16
    Fragment Screening Reveals Novel Scaffolds against Sirtuin-2-Related Protein 1 from <i>Trypanosoma brucei</i>

    Fragment Screening Reveals Novel Scaffolds against Sirtuin-2-Related Protein 1 from <i>Trypanosoma brucei</i> Por Renan Augusto Gomes, Marcelo D. Polêto, Hugo Verli, Vitor M. Almeida, Sandro R. Marana, Andreas Bender, Bruna Fleck Godoi, Veridiana de Melo Rodrigues, Flávio da Silva Emery, Gustavo Henrique Goulart Trossini

    Publicado em 2024
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  17. 17
    On the synthesis of quinone-based BODIPY hybrids: New insights on antitumor activity and mechanism of action in cancer cells

    On the synthesis of quinone-based BODIPY hybrids: New insights on antitumor activity and mechanism of action in cancer cells Por Talita B. Gontijo, Rossimiriam Pereira de Freitas, Flávio da Silva Emery, Leandro F. Pedrosa, José Barros Neto, Bruno C. Cavalcanti, Cláudia Pessoa, Aaron King, Fabio De Moliner, Marc Vendrell, Eufrânio N. da Silva Júnior

    Publicado em 2017
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  18. 18
    3-Phenylcoumarin derivatives selectively modulate different steps of reactive oxygen species production by immune complex-stimulated human neutrophils

    3-Phenylcoumarin derivatives selectively modulate different steps of reactive oxygen species production by immune complex-stimulated human neutrophils Por Micássio Fernandes de Andrade, Luciana M. Kabeya, Ana Elisa Caleiro Seixas Azzolini, Everton O.L. Santos, Andréa S.G. Figueiredo-Rinhel, Márcio R.P. Paris, Flávio da Silva Emery, Mônica Tallarico Pupo, Yara Maria Lucisano-Valim

    Publicado em 2013
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  19. 19
    Trypanosoma cruzi Sirtuin 2 as a Relevant Druggable Target: New Inhibitors Developed by Computer-Aided Drug Design

    Trypanosoma cruzi Sirtuin 2 as a Relevant Druggable Target: New Inhibitors Developed by Computer-Aided Drug Design Por Gláucio Monteiro Ferreira, Thales Kronenberger, Vinícius Gonçalves Maltarollo, Antti Poso, Fernando de Moura Gatti, Vitor M. Almeida, Sandro R. Marana, Carla D. Lopes, Daiane Y. Tezuka, Sérgio de Albuquerque, Flávio da Silva Emery, Gustavo Henrique Goulart Trossini

    Publicado em 2023
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  20. 20
    1,4- Addition of diazomethane to a heterodiene: a direct preparation of the oxazolic ring

    1,4- Addition of diazomethane to a heterodiene: a direct preparation of the oxazolic ring Por Flávio da Silva Emery, Raphael S. F. Silva, Kelly C. G. de Moura, M. C. F. R. Pinto, Mauro Barbosa de Amorim, V.R.S. Malta, R.H.A. Santos, Káthia M. Honório, Albérico B. F. da Silva, António Pinto

    Publicado em 2007
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