Resultats de la cerca - Fernando Lopitz‐Otsoa

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  1. 1
    S-Adenosylmethionine: A Multifaceted Regulator in Cancer Pathogenesis and Therapy

    S-Adenosylmethionine: A Multifaceted Regulator in Cancer Pathogenesis and Therapy per David Fernández‐Ramos, Fernando Lopitz‐Otsoa, Shelly C. Lu, José M. Mato

    Publicat 2025
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  2. 2
    Efficient protection and isolation of ubiquitylated proteins using tandem ubiquitin‐binding entities

    Efficient protection and isolation of ubiquitylated proteins using tandem ubiquitin‐binding entities per Roland Hjerpe, Fabienne Aillet, Fernando Lopitz‐Otsoa, Valérie Lang, Patrick England, Manuel S. Rodríguez

    Publicat 2009
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  3. 3
    Heterologous SUMO-2/3-Ubiquitin Chains Optimize IκBα Degradation and NF-κB Activity

    Heterologous SUMO-2/3-Ubiquitin Chains Optimize IκBα Degradation and NF-κB Activity per Fabienne Aillet, Fernando Lopitz‐Otsoa, Isabel Egaña, Roland Hjerpe, Paul E. Fraser, Ronald T. Hay, Manuel S. Rodríguez, Valérie Lang

    Publicat 2012
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  4. 4
    Kaposi's Sarcoma-Associated Herpesvirus Protein LANA2 Disrupts PML Oncogenic Domains and Inhibits PML-Mediated Transcriptional Repression of the Survivin Gene

    Kaposi's Sarcoma-Associated Herpesvirus Protein LANA2 Disrupts PML Oncogenic Domains and Inhibits PML-Mediated Transcriptional Repression of the Survivin Gene per Laura Marcos-Villar, Fernando Lopitz‐Otsoa, Pedro Pablo Ferrer Gallego, César Muñoz‐Fontela, José González, Michela Campagna, Gao Shou-Jiang, Manuel S. Rodríguez, Carmen Rivas

    Publicat 2009
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  5. 5
    Scavenger Receptors Mediate the Role of SUMO and Ftz-f1 in Drosophila Steroidogenesis

    Scavenger Receptors Mediate the Role of SUMO and Ftz-f1 in Drosophila Steroidogenesis per Ana Talamillo, Leire Herboso, Lucía Pirone, Coralia Pérez, Monika González-Lopez, Jonatan Sánchez, Ugo Mayor, Fernando Lopitz‐Otsoa, Manuel S. Rodríguez, James D. Sutherland, Rosa Barrio

    Publicat 2013
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  6. 6
    The RING ubiquitin E3 RNF114 interacts with A20 and modulates NF-κB activity and T-cell activation

    The RING ubiquitin E3 RNF114 interacts with A20 and modulates NF-κB activity and T-cell activation per M S Rodriguez, I Egaña, Fernando Lopitz‐Otsoa, Fabienne Aillet, M P Lopez-Mato, Akaitz Dorronsoro, S Lobato-Gil, James D. Sutherland, Rosa Barrio, C Trigueros, V Lang

    Publicat 2014
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  7. 7
    Aramchol downregulates stearoyl CoA-desaturase 1 in hepatic stellate cells to attenuate cellular fibrogenesis

    Aramchol downregulates stearoyl CoA-desaturase 1 in hepatic stellate cells to attenuate cellular fibrogenesis per Dipankar Bhattacharya, Brittany Basta, José M. Mato, Amanda J. Craig, David Fernández‐Ramos, Fernando Lopitz‐Otsoa, Darya Tsvirkun, Liat Hayardeny, Vasuretha Chandar, Robert E. Schwartz, Augusto Villanueva, Scott L. Friedman

    Publicat 2021
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  8. 8
    Regulation of the tumor suppressor PTEN by SUMO

    Regulation of the tumor suppressor PTEN by SUMO per José González, Michela Campagna, Ana Ortega-Molina, Laura Marcos-Villar, Carlos F. de la Cruz-Herrera, Dolores González de Llano, Pedro Pablo Ferrer Gallego, Fernando Lopitz‐Otsoa, Mariano Estéban, Manuel S. Rodríguez, Manuel Serrano, Carmen Rivas

    Publicat 2012
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  9. 9
    SARS-CoV-2 Infection Dysregulates the Metabolomic and Lipidomic Profiles of Serum

    SARS-CoV-2 Infection Dysregulates the Metabolomic and Lipidomic Profiles of Serum per Chiara Bruzzone, Maider Bizkarguenaga, Rubén Gil‐Redondo, Tammo Diercks, Eunate Arana‐Arri, Aitor García de Vicuña, Marisa Seco, Alexandre Bosch, Asís Palazón, Itxaso San Juan, Ana Laín, Jon Gil‐Martínez, Ganeko Bernardo‐Seisdedos, David Fernández‐Ramos, Fernando Lopitz‐Otsoa, Nieves Embade, Shelly C. Lu, José M. Mato, Óscar Millet

    Publicat 2020
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  10. 10
    A morphological method for ammonia detection in liver

    A morphological method for ammonia detection in liver per Virginia Gutiérrez-de-Juan, Sergio López de Davalillo, David Fernández‐Ramos, Lucía Barbier‐Torres, Imanol Zubiete‐Franco, Pablo Fernández‐Tussy, Jorge Simón, Fernando Lopitz‐Otsoa, Javier de las Heras, Paula Iruzubieta, M. Arias, Erica Villa, Javier Crespo, Raúl J. Andrade, M. Isabel Lucena, Marta Varela‐Rey, Shelly C. Lu, José M. Mato, Teresa C. Delgado, María Luz Martínez‐Chantar

    Publicat 2017
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  11. 11
    Depletion of mitochondrial methionine adenosyltransferase α1 triggers mitochondrial dysfunction in alcohol-associated liver disease

    Depletion of mitochondrial methionine adenosyltransferase α1 triggers mitochondrial dysfunction in alcohol-associated liver disease per Lucía Barbier‐Torres, Ben J. Murray, Jin Won Yang, Jiaohong Wang, Michitaka Matsuda, Aaron Robinson, Aleksandra Binek, Wei Fan, David Fernández‐Ramos, Fernando Lopitz‐Otsoa, María R Luque-Urbano, Óscar Millet, Nirmala Mavila, Hui Peng, Komal Ramani, Roberta A. Gottlieb, Zhaoli Sun, Suthat Liangpunsakul, Ekihiro Seki, Jennifer E. Van Eyk, José M. Mato, Shelly C. Lu

    Publicat 2022
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  12. 12
    Stabilization of LKB1 and Akt by neddylation regulates energy metabolism in liver cancer

    Stabilization of LKB1 and Akt by neddylation regulates energy metabolism in liver cancer per Lucía Barbier‐Torres, Teresa C. Delgado, Juan L. García‐Rodríguez, Imanol Zubiete‐Franco, David Fernández‐Ramos, Xabier Buqué, Ainara Cano, Virginia Gutiérrez‐de Juan, Itziar Fernández-Domínguez, Fernando Lopitz‐Otsoa, Pablo Fernández‐Tussy, Loreto Boix, Jordi Bruix, Erica Villa, Azucena Castro, Shelly C. Lu, Patricia Aspichueta, Dimitris P. Xirodimas, Marta Varela‐Rey, José M. Mato, Naiara Beraza, María Luz Martínez‐Chantar

    Publicat 2014
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  13. 13
    Deregulated neddylation in liver fibrosis

    Deregulated neddylation in liver fibrosis per Imanol Zubiete‐Franco, Pablo Fernández‐Tussy, Lucía Barbier‐Torres, Jorge Simón, David Fernández‐Ramos, Fernando Lopitz‐Otsoa, Virginia Gutiérrez‐de Juan, Sergio López de Davalillo, Antonio Martín Duce, Paula Iruzubieta, Daniel Taibo, Javier Crespo, Juan Caballería, Erica Villa, Igor Aurrekoetxea, Patricia Aspichueta, Marta Varela‐Rey, Shelly C. Lu, José M. Mato, Naiara Beraza, Teresa C. Delgado, María Luz Martínez‐Chantar

    Publicat 2016
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  14. 14
    Methionine and S-adenosylmethionine levels are critical regulators of PP2A activity modulating lipophagy during steatosis

    Methionine and S-adenosylmethionine levels are critical regulators of PP2A activity modulating lipophagy during steatosis per Imanol Zubiete‐Franco, Juan L. García‐Rodríguez, Maite Martinez‐Uña, Nuria Martínez-López, Ashwin Woodhoo, V.G. de Juan, Naiara Beraza, Sergio Lage, Fernando Andrade, Marta Llarena, Luis Aldámiz‐Echevarría, David Fernández‐Ramos, Juan Manuel Falcón‐Pérez, Fernando Lopitz‐Otsoa, Pablo Fernández‐Tussy, Lucía Barbier‐Torres, Zigmund Luka, Conrad Wagner, Carmelo García‐Monzón, Shelly C. Lu, Patricia Aspichueta, José M. Mato, María Luz Martínez‐Chantar, Marta Varela‐Rey

    Publicat 2015
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  15. 15
    MiR-873-5p acts as an epigenetic regulator in early stages of liver fibrosis and cirrhosis

    MiR-873-5p acts as an epigenetic regulator in early stages of liver fibrosis and cirrhosis per David Fernández‐Ramos, Pablo Fernández‐Tussy, Fernando Lopitz‐Otsoa, Virginia Gutiérrez-de-Juan, Nicolás Navasa, Lucía Barbier‐Torres, Imanol Zubiete‐Franco, Jorge Simón, Agustín F. Fernández, Ander Arbelaiz, Ana M. Aransay, José Luis Lavín, Naiara Beraza, María J. Perugorria, Jesús M. Bañales, Erica Villa, Mario F. Fraga, Juan Anguíta, Matías A. Ávila, Carmen Berasain, Paula Iruzibieta, Javier Crespo, Shelly C. Lu, Marta Varela‐Rey, José M. Mato, Teresa C. Delgado, María Luz Martínez‐Chantar

    Publicat 2018
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  16. 16
    SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer

    SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer per Imanol Zubiete‐Franco, Juan L. García‐Rodríguez, Fernando Lopitz‐Otsoa, Marina Serrano‐Maciá, Jorge Simón, Pablo Fernández‐Tussy, Lucía Barbier‐Torres, David Fernández‐Ramos, Virginia Gutiérrez-de-Juan, Sergio López de Davalillo, Onintza Carlevaris, Adolfo Beguiristain Gómez, Erica Villa, Diego F. Calvisi, César Martı́n, Edurne Berra, Patricia Aspichueta, Naiara Beraza, Marta Varela‐Rey, Matías A. Ávila, Manuel S. Rodríguez, José M. Mato, Irene Díaz‐Moreno, Antonio Dı́az-Quintana, Teresa C. Delgado, María Luz Martínez‐Chantar

    Publicat 2018
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  17. 17
    miR-873-5p targets mitochondrial GNMT-Complex II interface contributing to non-alcoholic fatty liver disease

    miR-873-5p targets mitochondrial GNMT-Complex II interface contributing to non-alcoholic fatty liver disease per Pablo Fernández‐Tussy, David Fernández‐Ramos, Fernando Lopitz‐Otsoa, Jorge Simón, Lucía Barbier‐Torres, Beatriz Gómez‐Santos, Maitane Núñez-García, Mikel Azkargorta, Virginia Gutiérrez‐de Juan, Marina Serrano‐Maciá, Rubén Rodríguez‐Agudo, Paula Iruzubieta, Juan Anguíta, Rui E. Castro, Devin Champagne, Mercedes Rincón, Félix Elortza, Anita Arslanow, Marcin Krawczyk, Frank Lammert, Mélanie Kirchmeyer, Iris Behrmann, Javier Crespo, Shelly C. Lu, José M. Mato, Marta Varela‐Rey, Patricia Aspichueta, Teresa C. Delgado, María Luz Martínez‐Chantar

    Publicat 2019
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  18. 18
    The mitochondrial negative regulator MCJ is a therapeutic target for acetaminophen-induced liver injury

    The mitochondrial negative regulator MCJ is a therapeutic target for acetaminophen-induced liver injury per Lucía Barbier‐Torres, Paula Iruzubieta, David Fernández‐Ramos, Teresa C. Delgado, Daniel Taibo, Virginia Guitiérrez-de-Juan, Marta Varela‐Rey, Mikel Azkargorta, Nicolás Navasa, Pablo Fernández‐Tussy, Imanol Zubiete‐Franco, Jorge Simón, Fernando Lopitz‐Otsoa, Sofía Lachiondo‐Ortega, Javier Crespo, Steven Masson, Misti McCain, Erica Villa, Helen L. Reeves, Félix Elortza, M. Isabel Lucena, María Isabel Hernández‐Álvarez, António Zorzano, Raúl J. Andrade, Shelly C. Lu, José M. Mato, Juan Anguíta, Mercedes Rincón, María Luz Martínez‐Chantar

    Publicat 2017
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  19. 19
    Targeting Hepatic Glutaminase 1 Ameliorates Non-alcoholic Steatohepatitis by Restoring Very-Low-Density Lipoprotein Triglyceride Assembly

    Targeting Hepatic Glutaminase 1 Ameliorates Non-alcoholic Steatohepatitis by Restoring Very-Low-Density Lipoprotein Triglyceride Assembly per Jorge Simón, Maitane Núñez-García, Pablo Fernández‐Tussy, Lucía Barbier‐Torres, David Fernández‐Ramos, Beatriz Gómez‐Santos, Xabier Buqué, Fernando Lopitz‐Otsoa, Naroa Goikoetxea‐Usandizaga, Marina Serrano‐Maciá, Rubén Rodríguez‐Agudo, Maider Bizkarguenaga, Imanol Zubiete‐Franco, Virginia Gutiérrez‐de Juan, Diana Cabrera, Cristina Alonso, Paula Iruzubieta, Manuel Romero‐Gómez, Sebastiaan van Liempd, Azucena Castro, Rubén Nogueiras, Marta Varela‐Rey, Juan Manuel Falcón‐Pérez, Erica Villa, Javier Crespo, Shelly C. Lu, José M. Mato, Patricia Aspichueta, Teresa C. Delgado, María Luz Martínez‐Chantar

    Publicat 2020
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  20. 20
    Neddylation inhibition ameliorates steatosis in NAFLD by boosting hepatic fatty acid oxidation via the DEPTOR-mTOR axis

    Neddylation inhibition ameliorates steatosis in NAFLD by boosting hepatic fatty acid oxidation via the DEPTOR-mTOR axis per Marina Serrano‐Maciá, Jorge Simón, Maria J. Gonzalez‐Rellan, Mikel Azkargorta, Naroa Goikoetxea‐Usandizaga, Fernando Lopitz‐Otsoa, Diego Sáenz de Urturi, Rubén Rodríguez‐Agudo, Sofía Lachiondo‐Ortega, María Mercado-Gómez, Virginia Gutiérrez de Juan, Maider Bizkarguenaga, David Fernández‐Ramos, Xabier Buqué, Guido Baselli, Luca Valenti, Paula Iruzubieta, Javier Crespo, Erica Villa, Jesús M. Bañales, Matías A. Ávila, José J.G. Marı́n, Patricia Aspichueta, James D. Sutherland, Rosa Barrio, Ugo Mayor, Félix Elortza, Dimitris P. Xirodimas, Rubén Nogueiras, Teresa C. Delgado, María Luz Martínez‐Chantar

    Publicat 2021
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