Search Results - Fengling Liu
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Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 Å resolution crystal structures of HIV‐1 protease mutants with substrate analogs by Yunfeng Tie, Péter Boross, Yuan‐Fang Wang, L. Gaddis, Fengling Liu, Xianfeng Chen, József Tözsér, Robert W. Harrison, Irene T. Weber
Published 2005Artigo -
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Effectiveness of Nonpeptide Clinical Inhibitor TMC-114 on HIV-1 Protease with Highly Drug Resistant Mutations D30N, I50V, and L90M by Andrey Kovalevsky, Yunfeng Tie, Fengling Liu, Péter Boross, Yuan‐Fang Wang, Sofiya Leshchenko, Arun K. Ghosh, Robert W. Harrison, Irene T. Weber
Published 2006Artigo
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Biology
Biochemistry
Chemistry
Enzyme
Protease
Gene
HIV-1 protease
Human immunodeficiency virus (HIV)
Virology
Active site
Organic chemistry
Stereochemistry
Antiretroviral therapy
Binding site
Mutant
Viral load
Crystallography
Darunavir
Dimer
Hydrolase
Protease inhibitor (pharmacology)
Receptor
Biophysics
Cancer
Cleavage (geology)
Composite material
Computer science
Crystal structure
Diastereomer
Dissociation constant