Хайлтын үр дүнгүүд - Farren, Matthew

Signaling Pathways as Therapeutic Targets in Biliary Tract Cancer -н Yang, Jennifer, Farren, Matthew R., Ahn, Daniel, Bekaii-Saab, Tanios, Lesinski, Gregory B.

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Stressful Presentations: Mild Cold Stress in Laboratory Mice Influences Phenotype of Dendritic Cells in Naïve and Tumor-Bearing Mice -н Kokolus, Kathleen M., Spangler, Haley M., Povinelli, Benjamin J., Farren, Matthew R., Lee, Kelvin P., Repasky, Elizabeth A.

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Napabucasin (BBI 608) a Potent Chemoradio-Sensitizer in Rectal Cancer -н Nagaraju, Ganji Purnachandra, Farran, Batoul, Farren, Matthew, Chalikonda, Gayathri, Wu, Christina, Lesinski, Gregory B., El-Rayes, Bassel F.

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Tumor-Induced STAT3 Signaling in Myeloid Cells Impairs Dendritic Cell Generation by Decreasing PKCβII Abundance -н Farren, Matthew R., Carlson, Louise M., Netherby, Colleen S., Lindner, Inna, Li, Pui-Kai, Gabrilovich, Dmitry I., Abrams, Scott I., Lee, Kelvin P.

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Protein Kinase C Isoforms ζ and ι Mediate Collagenase Expression and Cartilage Destruction via STAT3- and ERK-dependent c-fos Induction -н Litherland, Gary J., Elias, Martina S., Hui, Wang, Macdonald, Christopher D., Catterall, Jonathon B., Barter, Matt J., Farren, Matthew J., Jefferson, Matthew, Rowan, Andrew D.

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Myeloid-derived suppressor cell development is regulated by a STAT/IRF-8 axis -н Waight, Jeremy D., Netherby, Colleen, Hensen, Mary L., Miller, Austin, Hu, Qiang, Liu, Song, Bogner, Paul N., Farren, Matthew R., Lee, Kelvin P., Liu, Kebin, Abrams, Scott I.

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Systemic immune activity predicts overall survival in treatment naïve patients with metastatic pancreatic cancer -н Farren, Matthew R., Mace, Thomas A., Geyer, Susan, Mikhail, Sameh, Wu, Christina, Ciombor, Kristen, Tahiri, Sanaa, Ahn, Daniel, Noonan, Anne M., Villalona-Calero, Miguel, Bekaii-Saab, Tanios, Lesinski, Gregory B.

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The exportin-1 inhibitor selinexor exerts superior anti-tumor activity when combined with T cell checkpoint inhibitors -н Farren, Matthew R., Hennessey, Rebecca C., Shakya, Reena, Elnaggar, Omar, Young, Gregory, Kendra, Kari, Landesman, Yosef, Elloul, Sivan, Crochiere, Marsha, Klebanov, Boris, Kashyap, Trinayan, Burd, Christin E., Lesinski, Gregory B.

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RNA-Seq Differentiates Tumour and Host mRNA Expression Changes Induced by Treatment of Human Tumour Xenografts with the VEGFR Tyrosine Kinase Inhibitor Cediranib -н Bradford, James R., Farren, Matthew, Powell, Steve J., Runswick, Sarah, Weston, Susie L., Brown, Helen, Delpuech, Oona, Wappett, Mark, Smith, Neil R., Carr, T. Hedley, Dry, Jonathan R., Gibson, Neil J., Barry, Simon T.

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Soy isoflavones and their metabolites modulate cytokine-induced natural killer cell function -н Mace, Thomas A., Ware, Michael B., King, Samantha A., Loftus, Shannon, Farren, Matthew R., McMichael, Elizabeth, Scoville, Steven, Geraghty, Connor, Young, Gregory, Carson, William E., Clinton, Steven K., Lesinski, Gregory B.

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Immunologic alterations in the pancreatic cancer microenvironment of patients treated with neoadjuvant chemotherapy and radiotherapy -н Farren, Matthew R., Sayegh, Layal, Ware, Michael Brandon, Chen, Hsiao-Rong, Gong, Jingjing, Liang, Yan, Krasinskas, Alyssa, Maithel, Shishir K., Zaidi, Mohammad, Sarmiento, Juan M., Kooby, David, Patel, Pretesh, El-Rayes, Bassel, Shaib, Walid, Lesinski, Gregory B.

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A multi-center, single-arm, phase Ib study of pembrolizumab (MK-3475) in combination with chemotherapy for patients with advanced colorectal cancer: HCRN GI14-186 -н Herting, Cameron J., Farren, Matthew R., Tong, Yan, Liu, Ziyue, O’Neil, Bert, Bekaii-Saab, Tanios, Noonan, Anne, McQuinn, Christopher, Mace, Thomas A., Shaib, Walid, Wu, Christina, El-Rayes, Bassel F., Shahda, Safi, Lesinski, Gregory B.

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Dual Inhibition of MEK and PI3K/Akt Rescues Cancer Cachexia through Both Tumor Extrinsic and Intrinsic Activities -н Talbert, Erin E., Yang, Jennifer, Mace, Thomas A., Farren, Matthew R., Farris, Alton B., Young, Gregory S., Elnaggar, Omar, Che, Zheng, Timmers, Cynthia D., Rajasekera, Priyani, Maskarinec, Jennifer M., Bloomston, Mark, Bekaii-Saab, Tanios, Guttridge, Denis C., Lesinski, Gregory B.

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CD28 Promotes Plasma Cell Survival, Sustained Antibody Responses, and BLIMP-1 Upregulation through Its Distal PYAP Proline Motif -н Rozanski, Cheryl H., Utley, Adam, Carlson, Louise M., Farren, Matthew R., Murray, Megan, Russell, Lisa M., Nair, Jayakumar R., Yang, ZhengYu, Brady, William, Garrett-Sinha, Lee Ann, Schoenberger, Stephen P., Green, Jonathan M., Boise, Lawrence H., Lee, Kelvin P.

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Heat shock protein-90 inhibition alters activation of pancreatic stellate cells and enhances the efficacy of PD-1 blockade in pancreatic cancer. -н Zhang, Yuchen, Ware, Michael B., Zaidi, Mohammad Y., Ruggieri, Amanda N., Olson, Brian M., Komar, Hannah, Farren, Matthew R., Nagaraju, Ganji Purnachandra, Zhang, Chao, Chen, Zhengjia, Sarmiento, Juan M., Ahmed, Rafi, Maithel, Shishir K., El-Rayes, Bassel F., Lesinski, Gregory B.

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Circulating monocyte chemoattractant protein‐1 (MCP‐1) is associated with cachexia in treatment‐naïve pancreatic cancer patients -н Talbert, Erin E., Lewis, Heather L., Farren, Matthew R., Ramsey, Mitchell L., Chakedis, Jeffery M., Rajasekera, Priyani, Haverick, Ericka, Sarna, Angela, Bloomston, Mark, Pawlik, Timothy M., Zimmers, Teresa A., Lesinski, Gregory B., Hart, Phil A., Dillhoff, Mary E., Schmidt, Carl R., Guttridge, Denis C.

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Suppressive myeloid cells are expanded by biliary tract cancer-derived cytokines in vitro and associate with aggressive disease -н Ware, Michael B., Zaidi, Mohammad Y., Yang, Jennifer, Turgeon, Michael K., Krasinskas, Alyssa, Mace, Thomas A., Keenan, Kaitlin, Farren, Matthew R., Ruggieri, Amanda N., Li, Yiman, Zhang, Chao, Chen, Zhengjia, Young, Gregory S., Elnaggar, Omar, Che, Zheng, Maithel, Shishir K., Bekaii-Saab, Tanios, El-Rayes, Bassel, Lesinski, Gregory B.

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Randomized Phase 2 Trial of the Oncolytic Virus Pelareorep (Reolysin) in Upfront Treatment of Metastatic Pancreatic Adenocarcinoma -н Noonan, Anne M, Farren, Matthew R, Geyer, Susan M, Huang, Ying, Tahiri, Sanaa, Ahn, Daniel, Mikhail, Sameh, Ciombor, Kristen K, Pant, Shubham, Aparo, Santiago, Sexton, Jennifer, Marshall, John L, Mace, Thomas A, Wu, Christina S, El-Rayes, Bassel, Timmers, Cynthia D, Zwiebel, James, Lesinski, Gregory B, Villalona-Calero, Miguel A, Bekaii-Saab, Tanios S

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Lipocalin-2 Promotes Pancreatic Ductal Adenocarcinoma by Regulating Inflammation in the Tumor Microenvironment -н Gomez-Chou, Sobeyda B., Swidnicka-Siergiejko, Agnieszka Katarzyna, Badi, Niharika, Chavez-Tomar, Myrriah, Lesinski, Gregory B., Bekaii-Saab, Tanios, Farren, Matthew R., Mace, Thomas A., Schmidt, Carl, Liu, Yan, Deng, Defeng, Hwang, Rosa F., Zhou, Liran, Moore, Todd, Chatterjee, Deyali, Wang, Huamin, Leng, Xiaohong, Arlinghaus, Ralph B., Logsdon, Craig D., Cruz-Monserrate, Zobeida

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Circulating Interleukin-6 is Associated with Disease Progression, but not Cachexia in Pancreatic Cancer -н Ramsey, Mitchell L., Talbert, Erin, Ahn, Daniel, Bekaii-Saab, Tanios, Badi, Niharika, Bloomston, P. Mark, Conwell, Darwin L., Cruz-Monserrate, Zobeida, Dillhoff, Mary, Farren, Matthew R., Hinton, Alice, Krishna, Somashekar G., Lesinski, Gregory B., Mace, Thomas, Manilchuk, Andrei, Noonan, Anne, Pawlik, Timothy M., Rajasekera, Priyani V., Schmidt, Carl, Guttridge, Denis, Hart, Phil A.

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