Ngā hua rapu - Fabbro, Doriano

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  1. 1
    PI3K/mTOR Pathway Inhibition: Opportunities in Oncology and Rare Genetic Diseases

    PI3K/mTOR Pathway Inhibition: Opportunities in Oncology and Rare Genetic Diseases mā Hillmann, Petra, Fabbro, Doriano

    I whakaputaina 2019
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  2. 2
    Ten things you should know about protein kinases: IUPHAR Review 14

    Ten things you should know about protein kinases: IUPHAR Review 14 mā Fabbro, Doriano, Cowan-Jacob, Sandra W, Moebitz, Henrik

    I whakaputaina 2015
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  3. 3
    Targeting Sphingosine Kinase 1 in Carcinoma Cells Decreases Proliferation and Survival by Compromising PKC Activity and Cytokinesis

    Targeting Sphingosine Kinase 1 in Carcinoma Cells Decreases Proliferation and Survival by Compromising PKC Activity and Cytokinesis mā Kotelevets, Nataliya, Fabbro, Doriano, Huwiler, Andrea, Zangemeister-Wittke, Uwe

    I whakaputaina 2012
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  4. 4
    Correction: Targeting Sphingosine Kinase 1 in Carcinoma Cells Decreases Proliferation and Survival by Compromising PKC Activity and Cytokinesis

    Correction: Targeting Sphingosine Kinase 1 in Carcinoma Cells Decreases Proliferation and Survival by Compromising PKC Activity and Cytokinesis mā Kotelevets, Nataliya, Fabbro, Doriano, Huwiler, Andrea, Zangemeister-Wittke, Uwe

    I whakaputaina 2013
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  5. 5
    NMR reveals the allosteric opening and closing of Abelson tyrosine kinase by ATP-site and myristoyl pocket inhibitors

    NMR reveals the allosteric opening and closing of Abelson tyrosine kinase by ATP-site and myristoyl pocket inhibitors mā Skora, Lukasz, Mestan, Jürgen, Fabbro, Doriano, Jahnke, Wolfgang, Grzesiek, Stephan

    I whakaputaina 2013
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  6. 6
    CSIG-26. MOLECULAR DETERMINANTS OF SENSITIVITY TO PI3K/AKT/mTOR PATHWAY INHIBITION IN GLIOBLASTOMA

    CSIG-26. MOLECULAR DETERMINANTS OF SENSITIVITY TO PI3K/AKT/mTOR PATHWAY INHIBITION IN GLIOBLASTOMA mā von Achenbach, Caroline, Weller, Michael, Kaulich, Kerstin, Gramatzki, Dorothee, Zacher, Angela, Fabbro, Doriano, Reifenberger, Guido, Szabo, Emese

    I whakaputaina 2018
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  7. 7
    Activation mutations of human c-KIT resistant to imatinib mesylate are sensitive to the tyrosine kinase inhibitor PKC412

    Activation mutations of human c-KIT resistant to imatinib mesylate are sensitive to the tyrosine kinase inhibitor PKC412 mā Growney, Joseph D., Clark, Jennifer J., Adelsperger, Jennifer, Stone, Richard, Fabbro, Doriano, Griffin, James D., Gilliland, D. Gary

    I whakaputaina 2005
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  8. 8
    The ceramide kinase inhibitor NVP-231 inhibits breast and lung cancer cell proliferation by inducing M phase arrest and subsequent cell death

    The ceramide kinase inhibitor NVP-231 inhibits breast and lung cancer cell proliferation by inducing M phase arrest and subsequent cell death mā Pastukhov, Oleksandr, Schwalm, Stephanie, Zangemeister-Wittke, Uwe, Fabbro, Doriano, Bornancin, Frederic, Japtok, Lukasz, Kleuser, Burkhard, Pfeilschifter, Josef, Huwiler, Andrea

    I whakaputaina 2014
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  9. 9
    Kinase Inhibition by Deoxy Analogues of the Resorcylic Lactone L-783277

    Kinase Inhibition by Deoxy Analogues of the Resorcylic Lactone L-783277 mā Liniger, Marc, Neuhaus, Christian, Hofmann, Tatjana, Fransioli-Ignazio, Luca, Jordi, Michel, Drueckes, Peter, Trappe, Jörg, Fabbro, Doriano, Altmann, Karl-Heinz

    I whakaputaina 2010
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  10. 10
    Stable expression of small interfering RNA sensitizes TEL-PDGFβR to inhibition with imatinib or rapamycin

    Stable expression of small interfering RNA sensitizes TEL-PDGFβR to inhibition with imatinib or rapamycin mā Chen, Jing, Wall, Nathan R., Kocher, Kerry, Duclos, Nicole, Fabbro, Doriano, Neuberg, Donna, Griffin, James D., Shi, Yang, Gilliland, D. Gary

    I whakaputaina 2004
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  11. 11
    RET/PTC INDUCED CELL GROWTH IS MEDIATED IN PART BY EPIDERMAL GROWTH RECEPTOR ACTIVATION: EVIDENCE FOR MOLECULAR AND FUNCTIONAL INTERACTIONS BETWEEN RET AND EGFR

    RET/PTC INDUCED CELL GROWTH IS MEDIATED IN PART BY EPIDERMAL GROWTH RECEPTOR ACTIVATION: EVIDENCE FOR MOLECULAR AND FUNCTIONAL INTERACTIONS BETWEEN RET AND EGFR mā Croyle, Michelle, Akeno, Nagako, Knauf, Jeffrey A., Traxler, Peter, Fabbro, Doriano, Chen, Xu, Baumgartner, Jacqueline E., Lane, Heidi A., Fagin, James A.

    I whakaputaina 2008
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  12. 12
    Dramatic Inhibition of Retinal and Choroidal Neovascularization by Oral Administration of a Kinase Inhibitor

    Dramatic Inhibition of Retinal and Choroidal Neovascularization by Oral Administration of a Kinase Inhibitor mā Seo, Man Seong, Kwak, Nohoon, Ozaki, Hiroaki, Yamada, Haruhiko, Okamoto, Naoyuki, Yamada, Eri, Fabbro, Doriano, Hofmann, Francesco, Wood, Jeanette M., Campochiaro, Peter A.

    I whakaputaina 1999
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  13. 13
    Structural biology contributions to the discovery of drugs to treat chronic myelogenous leukaemia

    Structural biology contributions to the discovery of drugs to treat chronic myelogenous leukaemia mā Cowan-Jacob, Sandra W., Fendrich, Gabriele, Floersheimer, Andreas, Furet, Pascal, Liebetanz, Janis, Rummel, Gabriele, Rheinberger, Paul, Centeleghe, Mario, Fabbro, Doriano, Manley, Paul W.

    I whakaputaina 2006
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  14. 14
    7,8-Dichloro-1-oxo-β-carbolines as a Versatile Scaffold for the Development of Potent and Selective Kinase Inhibitors with Unusual Binding Modes†

    7,8-Dichloro-1-oxo-β-carbolines as a Versatile Scaffold for the Development of Potent and Selective Kinase Inhibitors with Unusual Binding Modes† mā Huber, Kilian, Brault, Laurent, Fedorov, Oleg, Gasser, Christelle, Filippakopoulos, Panagis, Bullock, Alex N., Fabbro, Doriano, Trappe, Jörg, Schwaller, Jürg, Knapp, Stefan, Bracher, Franz

    I whakaputaina 2011
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  15. 15
    Sequence-specific antitumor activity of a phosphorothioate oligodeoxyribonucleotide targeted to human C-raf kinase supports an antisense mechanism of action in vivo

    Sequence-specific antitumor activity of a phosphorothioate oligodeoxyribonucleotide targeted to human C-raf kinase supports an antisense mechanism of action in vivo mā Monia, Brett P., Sasmor, Henri, Johnston, Joseph F., Freier, Susan M., Lesnik, Elena A., Muller, Marcel, Geiger, Thomas, Altmann, Karl-Heinz, Moser, Heinz, Fabbro, Doriano

    I whakaputaina 1996
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  16. 16
    Preclinical Development of PQR514, a Highly Potent PI3K Inhibitor Bearing a Difluoromethyl–Pyrimidine Moiety

    Preclinical Development of PQR514, a Highly Potent PI3K Inhibitor Bearing a Difluoromethyl–Pyrimidine Moiety mā Borsari, Chiara, Rageot, Denise, Beaufils, Florent, Bohnacker, Thomas, Keles, Erhan, Buslov, Ivan, Melone, Anna, Sele, Alexander M., Hebeisen, Paul, Fabbro, Doriano, Hillmann, Petra, Wymann, Matthias P.

    I whakaputaina 2019
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  17. 17
    Specific CLK Inhibitors from a Novel Chemotype for Regulation of Alternative Splicing

    Specific CLK Inhibitors from a Novel Chemotype for Regulation of Alternative Splicing mā Fedorov, Oleg, Huber, Kilian, Eisenreich, Andreas, Filippakopoulos, Panagis, King, Oliver, Bullock, Alex N., Szklarczyk, Damian, Jensen, Lars J., Fabbro, Doriano, Trappe, Jörg, Rauch, Ursula, Bracher, Franz, Knapp, Stefan

    I whakaputaina 2011
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  18. 18
    Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA).

    Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA). mā Sarno, Stefania, de Moliner, Erika, Ruzzene, Maria, Pagano, Mario A, Battistutta, Roberto, Bain, Jenny, Fabbro, Doriano, Schoepfer, Joseph, Elliott, Matthew, Furet, Pascal, Meggio, Flavio, Zanotti, Giuseppe, Pinna, Lorenzo A

    I whakaputaina 2003
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  19. 19
    Effects of PKC412, nilotinib and imatinib against GIST-associated PDGFRA mutants with differential imatinib sensitivity: Mutant PDGFRA: PKC412, nilotinib, imatinib

    Effects of PKC412, nilotinib and imatinib against GIST-associated PDGFRA mutants with differential imatinib sensitivity: Mutant PDGFRA: PKC412, nilotinib, imatinib mā Weisberg, Ellen, Wright, Renee D., Jiang, Jingrui, Ray, Arghya, Moreno, Daisy, Manley, Paul W., Fabbro, Doriano, Hall-Meyers, Elizabeth, Catley, Laurie, Podar, Klaus, Kung, Andrew L., Griffin, James D.

    I whakaputaina 2006
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  20. 20
    THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Catalytic receptors

    THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Catalytic receptors mā Alexander, Stephen PH, Fabbro, Doriano, Kelly, Eamonn, Marrion, Neil V, Peters, John A, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Davies, Jamie A

    I whakaputaina 2017
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