Search Results - Emily A. Day

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  1. 1
    Metformin and feeding increase levels of the appetite-suppressing metabolite Lac-Phe in humans

    Metformin and feeding increase levels of the appetite-suppressing metabolite Lac-Phe in humans by Barry Scott, Emily A. Day, Katie L. O’Brien, John Scanlan, Grace Cromwell, Aine Ni Scannail, Marie E. McDonnell, David K. Finlay, Lydia Lynch

    Published 2024
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  2. 2
    The Na+/Glucose Cotransporter Inhibitor Canagliflozin Activates AMPK by Inhibiting Mitochondrial Function and Increasing Cellular AMP Levels

    The Na+/Glucose Cotransporter Inhibitor Canagliflozin Activates AMPK by Inhibiting Mitochondrial Function and Increasing Cellular AMP Levels by Simon A. Hawley, Rebecca J. Ford, Brennan K. Smith, Graeme J. Gowans, Sarah J. Mancini, Ryan D. Pitt, Emily A. Day, Ian P. Salt, Gregory R. Steinberg, D. Grahame Hardie

    Published 2016
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  3. 3
    Genetic deletion of mast cell serotonin synthesis prevents the development of obesity and insulin resistance

    Genetic deletion of mast cell serotonin synthesis prevents the development of obesity and insulin resistance by Julian M. Yabut, Eric M. Desjardins, Eric Chan, Emily A. Day, Julie M. Leroux, Bo Wang, Elizabeth D. Crane, Wesley Wong, Katherine M. Morrison, Justin D. Crane, Waliul I. Khan, Gregory R. Steinberg

    Published 2020
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  4. 4
    Salicylate improves macrophage cholesterol homeostasis via activation of Ampk

    Salicylate improves macrophage cholesterol homeostasis via activation of Ampk by Morgan D. Fullerton, Rebecca J. Ford, Chelsea McGregor, Nicholas D. LeBlond, Shayne A. Snider, Stephanie Stypa, Emily A. Day, Šárka Lhoták, Jonathan D. Schertzer, Richard C. Austin, Bruce E. Kemp, Gregory R. Steinberg

    Published 2015
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  5. 5
    Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis

    Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis by Stephen L. Pinkosky, Roger S. Newton, Emily A. Day, Rebecca J. Ford, Šárka Lhoták, Richard C. Austin, Carolyn M. Birch, Brennan K. Smith, С. И. Филиппов, Pieter H.E. Groot, Gregory R. Steinberg, Narendra D. Lalwani

    Published 2016
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  6. 6
    Metformin and salicylate synergistically activate liver AMPK, inhibit lipogenesis and improve insulin sensitivity

    Metformin and salicylate synergistically activate liver AMPK, inhibit lipogenesis and improve insulin sensitivity by Rebecca J. Ford, Morgan D. Fullerton, Stephen L. Pinkosky, Emily A. Day, John W. Scott, Jonathan S. Oakhill, Adam L. Bujak, Brennan K. Smith, Justin D. Crane, Regje M. E. Blümer, Katarina Marcinko, Bruce E. Kemp, Hertzel C. Gerstein, Gregory R. Steinberg

    Published 2015
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  7. 7
    Salsalate (Salicylate) Uncouples Mitochondria, Improves Glucose Homeostasis, and Reduces Liver Lipids Independent of AMPK-β1

    Salsalate (Salicylate) Uncouples Mitochondria, Improves Glucose Homeostasis, and Reduces Liver Lipids Independent of AMPK-β1 by Brennan K. Smith, Rebecca J. Ford, Eric M. Desjardins, Alex E. Green, Meghan C. Hughes, Vanessa P. Houde, Emily A. Day, Katarina Marcinko, Justin D. Crane, Emilio P. Mottillo, Christopher G. R. Perry, Bruce E. Kemp, Mark A. Tarnopolsky, Gregory R. Steinberg

    Published 2016
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  8. 8
    Rhythmic IL-17 production by γδ T cells maintains adipose de novo lipogenesis

    Rhythmic IL-17 production by γδ T cells maintains adipose de novo lipogenesis by Aaron Douglas, Brenneth Stevens, Miguel Rendas, Harry Kane, Evan B. Lynch, Britta Kunkemoeller, Karl A. Wessendorf-Rodriguez, Emily A. Day, Caroline E. Sutton, Martin Brennan, Katie L. O’Brien, Ayano C. Kohlgruber, Hannah Prendeville, Amanda Garza, Luke O'neill, Kingston H. G. Mills, Christian M. Metallo, Henrique Veiga‐Fernandes, Lydia Lynch

    Published 2024
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  9. 9
    Trained immunity causes myeloid cell hypercoagulability

    Trained immunity causes myeloid cell hypercoagulability by Aisling M. Rehill, Seán McCluskey, Anna E. Ledwith, Tristram A.J. Ryan, Betül Ünlü, Gemma Leon, Hugo Charles‐Messance, Edmund Gilbert, Paula Klavina, Emily A. Day, Judith A. Coppinger, Jamie M. O’Sullivan, Corrina McMahon, James S. O’Donnell, Annie M. Curtis, Luke O'neill, Frederick J. Sheedy, Roger J. S. Preston

    Published 2025
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  10. 10
    The pesticide chlorpyrifos promotes obesity by inhibiting diet-induced thermogenesis in brown adipose tissue

    The pesticide chlorpyrifos promotes obesity by inhibiting diet-induced thermogenesis in brown adipose tissue by Bo Wang, Evangelia E. Tsakiridis, Shuman Zhang, Andrea Llanos, Eric M. Desjardins, Julian M. Yabut, Alex E. Green, Emily A. Day, Brennan K. Smith, James Lally, Jianhan Wu, Amogelang R. Raphenya, Krishna Srinivasan, Andrew G. McArthur, Shingo Kajimura, Jagdish Suresh Patel, Michael G. Wade, Katherine M. Morrison, Alison C. Holloway, Gregory R. Steinberg

    Published 2021
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  11. 11
    Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK β1 isoforms

    Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK β1 isoforms by Stephen L. Pinkosky, John W. Scott, Eric M. Desjardins, Brennan K. Smith, Emily A. Day, Rebecca J. Ford, Christopher G. Langendorf, Naomi X.Y. Ling, Tracy L. Nero, Kim Loh, Sandra Galić, Ashfaqul Hoque, William J. Smiles, Kevin R. W. Ngoei, Michael W. Parker, Yan Yan, Karsten Melcher, Bruce E. Kemp, Jonathan S. Oakhill, Gregory R. Steinberg

    Published 2020
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  12. 12
    Metabolic function of PKM2 regulates ROS production and microbial killing by neutrophils

    Metabolic function of PKM2 regulates ROS production and microbial killing by neutrophils by Carlos Hiroji Hiroki, Camila M. Silva, Daniele C. Nascimento, Gabriel Azevedo Públio, Timna Varela Martins, Luis Eduardo Alves Damasceno, Flávio P. Veras, Paula Ramos Viacava, Fábio Yuji Sukesada, Emily A. Day, Alessia Zotta, Tristram A.J. Ryan, Rodrigo Moreira da Silva, Thiago M. Cunha, Norberto Peporine Lopes, Fernando Q. Cunha, Luke O'neill, José C. Alves‐Filho

    Published 2023
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  13. 13
    The metabolic function of pyruvate kinase M2 regulates reactive oxygen species production and microbial killing by neutrophils

    The metabolic function of pyruvate kinase M2 regulates reactive oxygen species production and microbial killing by neutrophils by Juliana E. Toller-Kawahisa, Carlos Hiroji Hiroki, Camila M. Silva, Daniele C. Nascimento, Gabriel Azevedo Públio, Timna Varela Martins, Luis Eduardo Alves Damasceno, Flávio P. Veras, Paula Ramos Viacava, Fábio Yuji Sukesada, Emily A. Day, Alessia Zotta, Tristram A.J. Ryan, Rodrigo Moreira da Silva, Thiago M. Cunha, Norberto Peporine Lopes, Fernando Q. Cunha, Luke O'neill, José C. Alves‐Filho

    Published 2023
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  14. 14
    Activation of Liver AMPK with PF-06409577 Corrects NAFLD and Lowers Cholesterol in Rodent and Primate Preclinical Models

    Activation of Liver AMPK with PF-06409577 Corrects NAFLD and Lowers Cholesterol in Rodent and Primate Preclinical Models by Ryan M. Esquejo, Christopher T. Salatto, Jake Delmore, Bina Albuquerque, Allan R. Reyes, Yuji Shi, Rob Moccia, Emily Cokorinos, Matthew Peloquin, Mara Monetti, Jason Barricklow, Eliza Bollinger, Brennan K. Smith, Emily A. Day, Chuong Nguyen, Kieran F. Geoghegan, John M. Kreeger, Alan Opsahl, Jessica Ward, Amit S. Kalgutkar, David A. Tess, Lynne Butler, Norimitsu Shirai, Timothy F. Osborne, Gregory R. Steinberg, Morris J. Birnbaum, Kimberly O. Cameron, Russell Miller

    Published 2018
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  15. 15
    Macrophage fumarate hydratase restrains mtRNA-mediated interferon production

    Macrophage fumarate hydratase restrains mtRNA-mediated interferon production by Alexander Hooftman, Christian G. Peace, Dylan G. Ryan, Emily A. Day, Ming Yang, Anne F. McGettrick, Maureen Yin, Erica N. Montano, Lihong Huo, Juliana E. Toller-Kawahisa, Vincent Zecchini, Tristram A.J. Ryan, Alfonso Bolado‐Carrancio, Alva M. Casey, Hiran A. Prag, Ana S.H. Costa, Gabriela De Los Santos, Mariko Ishimori, Daniel J. Wallace, Swamy Venuturupalli, Efterpi Nikitopoulou, Norma Frizzell, Cecilia Johansson, Alex von Kriegsheim, Michael P. Murphy, Caroline A. Jefferies, Christian Frezza, Luke O'neill

    Published 2023
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  16. 16
    Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon

    Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon by Tristram A.J. Ryan, Alexander Hooftman, Aisling M. Rehill, Matt D. Johansen, Eóin C. O’ Brien, Juliana E. Toller-Kawahisa, Mieszko M. Wilk, Emily A. Day, Hauke J. Weiss, Pourya Sarvari, Emilio G. Vozza, Fabian Schramm, Christian G. Peace, Alessia Zotta, Stefan Miemczyk, Christina Nalkurthi, Nicole G. Hansbro, Gavin McManus, Laura O’Doherty, Siobhán Gargan, Aideen Long, Jean Dunne, Cliona Ní Cheallaigh, Niall Conlon, Michael Carty, Padraic G. Fallon, Kingston H. G. Mills, Emma M. Creagh, James S. O’ Donnell, Paul J. Hertzog, Philip M. Hansbro, Rachel M. McLoughlin, Małgorzata Wygrecka, Roger J. S. Preston, Zbigniew Zasłona, Luke O'neill

    Published 2023
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