Resultats de la cerca - Elizaveta S. Leshchiner

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  1. 1
    Direct activation of full-length proapoptotic BAK

    Direct activation of full-length proapoptotic BAK per Elizaveta S. Leshchiner, Craig R. Braun, Geoffrey Bird, Loren D. Walensky

    Publicat 2013
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  2. 2
    Direct and selective small-molecule activation of proapoptotic BAX

    Direct and selective small-molecule activation of proapoptotic BAX per Evripidis Gavathiotis, Denis E. Reyna, Joseph A. Bellairs, Elizaveta S. Leshchiner, Loren D. Walensky

    Publicat 2012
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  3. 3
    The retinoblastoma protein induces apoptosis directly at the mitochondria

    The retinoblastoma protein induces apoptosis directly at the mitochondria per Keren I. Hilgendorf, Elizaveta S. Leshchiner, Simona Nedelcu, Mindy A. Maynard, Eliezer Calo, Alessandra Ianari, Loren D. Walensky, Jacqueline A. Lees

    Publicat 2013
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  4. 4
    Combinatorial Approach to Determine Functional Group Effects on Lipidoid-Mediated siRNA Delivery

    Combinatorial Approach to Determine Functional Group Effects on Lipidoid-Mediated siRNA Delivery per Kerry P. Mahon, Kevin T. Love, Kathryn A. Whitehead, June Qin, Akin Akinc, Elizaveta S. Leshchiner, Ignaty Leshchiner, Róbert Langer, Daniel G. Anderson

    Publicat 2010
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  5. 5
    Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices

    Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices per Elizaveta S. Leshchiner, Andrey A. Parkhitko, Gregory H. Bird, James Luccarelli, Joseph A. Bellairs, Silvia Escudero, Kwadwo Opoku-Nsiah, Marina Godes, Norbert Perrimon, Loren D. Walensky

    Publicat 2015
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  6. 6
    Development of Lipidoid–siRNA Formulations for Systemic Delivery to the Liver

    Development of Lipidoid–siRNA Formulations for Systemic Delivery to the Liver per Akin Akinc, Michael S. Goldberg, June Qin, J. Robert Dorkin, Christina Gamba‐Vitalo, Martin A. Maier, K. N. Jayaprakash, Muthusamy Jayaraman, Kallanthottathil G. Rajeev, Muthiah Manoharan, Victor Koteliansky, Ingo Röhl, Elizaveta S. Leshchiner, Róbert Langer, Daniel G. Anderson

    Publicat 2009
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  7. 7
    Small-molecule inhibitors directly target CARD9 and mimic its protective variant in inflammatory bowel disease

    Small-molecule inhibitors directly target CARD9 and mimic its protective variant in inflammatory bowel disease per Elizaveta S. Leshchiner, Jason S. Rush, Michael A. Durney, Zhifang Cao, Vlado Dančík, Benjamin Chittick, Huixian Wu, Adam Petrone, Joshua A. Bittker, Andrew J. Phillips, José R. Perez, Alykhan F. Shamji, Virendar K. Kaushik, Mark J. Daly, Daniel B. Graham, Stuart L. Schreiber, Ramnik J. Xavier

    Publicat 2017
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  8. 8
    Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation

    Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation per Zhifang Cao, Kara L. Conway, Robert J. W. Heath, Jason S. Rush, Elizaveta S. Leshchiner, Zaida G. Ramirez‐Ortiz, Natalia B. Nedelsky, Hailiang Huang, Aylwin Ng, Agnès Gardet, Shih‐Chin Cheng, Alykhan F. Shamji, John D. Rioux, Cisca Wijmenga, Mihai G. Netea, Terry K. Means, Mark J. Daly, Ramnik J. Xavier

    Publicat 2015
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  9. 9
    A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis

    A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis per Yilong Zou, Michael J. Palte, Amy Deik, Haoxin Li, John K. Eaton, Wenyu Wang, Yuen‐Yi Tseng, Rebecca Deasy, Maria Kost‐Alimova, Vlado Dančík, Elizaveta S. Leshchiner, Vasanthi S. Viswanathan, Sabina Signoretti, Toni K. Choueiri, Jesse S. Boehm, Bridget K. Wagner, John G. Doench, Clary B. Clish, Paul A. Clemons, Stuart L. Schreiber

    Publicat 2019
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  10. 10
    A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

    A combinatorial library of lipid-like materials for delivery of RNAi therapeutics per Akin Akinc, Andreas Zumbuehl, Michael S. Goldberg, Elizaveta S. Leshchiner, Valentina Busini, Naushad Hossain, Sergio Bacallado, David N. Nguyen, Jason Fuller, Rene Alvarez, Anna Borodovsky, Todd Borland, Rainer Constien, Antonin de Fougerolles, J. Robert Dorkin, K. N. Jayaprakash, Muthusamy Jayaraman, Matthias John, Victor Koteliansky, Muthiah Manoharan, Lubomir V. Nechev, June Qin, Timothy Racie, Denitza Raitcheva, Kallanthottathil G. Rajeev, Dinah W.Y. Sah, Jürgen Soutschek, Ivanka Toudjarska, Hans‐Peter Vornlocher, Tracy Zimmermann, Róbert Langer, Daniel G. Anderson

    Publicat 2008
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