Výsledky vyhledávání - Eleanor Wheeler

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  1. 1
    Genome-wide association studies and type 2 diabetes

    Genome-wide association studies and type 2 diabetes Autor Eleanor Wheeler, Inês Barroso

    Vydáno 2011
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  2. 2
    Proteogenomic links to human metabolic diseases

    Proteogenomic links to human metabolic diseases Autor Mine Koprulu, Julia Carrasco-Zanini, Eleanor Wheeler, Sam Lockhart, Nicola D. Kerrison, Nicholas J. Wareham, Maik Pietzner, Claudia Langenberg

    Vydáno 2023
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  3. 3
    Mapping biological influences on the human plasma proteome beyond the genome

    Mapping biological influences on the human plasma proteome beyond the genome Autor Julia Carrasco-Zanini, Eleanor Wheeler, Burulça Uluvar, Nicola D. Kerrison, Mine Koprulu, Nicholas J. Wareham, Maik Pietzner, Claudia Langenberg

    Vydáno 2024
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  4. 4
    Sex differences in the genetic regulation of the human plasma proteome

    Sex differences in the genetic regulation of the human plasma proteome Autor Mine Koprulu, Eleanor Wheeler, Nicola D. Kerrison, Spiros Denaxas, Julia Carrasco-Zanini, Chloe Orkin, Harry Hemingway, Nicholas J. Wareham, Maik Pietzner, Claudia Langenberg

    Vydáno 2025
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  5. 5
    Causal associations between cardiorespiratory fitness and type 2 diabetes

    Causal associations between cardiorespiratory fitness and type 2 diabetes Autor Lina Cai, Tomas I. Gonzales, Eleanor Wheeler, Nicola D. Kerrison, Felix R. Day, Claudia Langenberg, John R. B. Perry, Søren Brage, Nicholas J. Wareham

    Vydáno 2023
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  6. 6
    Quantifying the Relationship Between Physical Activity Energy Expenditure and Incident Type 2 Diabetes: A Prospective Cohort Study of Device-Measured Activity in 90,096 Adults

    Quantifying the Relationship Between Physical Activity Energy Expenditure and Incident Type 2 Diabetes: A Prospective Cohort Study of Device-Measured Activity in 90,096 Adults Autor Tessa Strain, Paddy C. Dempsey, Katrien Wijndaele, Stephen J. Sharp, Nicola D. Kerrison, Tomas I. Gonzales, Chunxiao Li, Eleanor Wheeler, Claudia Langenberg, Søren Brage, Nicholas J. Wareham

    Vydáno 2023
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  7. 7
    Meta-analysis investigating the role of interleukin-6 mediated inflammation in type 2 diabetes

    Meta-analysis investigating the role of interleukin-6 mediated inflammation in type 2 diabetes Autor Nicholas Bowker, Rupal Shah, Stephen J. Sharp, Jian’an Luan, Isobel D. Stewart, Eleanor Wheeler, Manuel A. R. Ferreira, Aris Baras, Nicholas J. Wareham, Claudia Langenberg, Luca A. Lotta

    Vydáno 2020
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  8. 8
    Mendelian Randomization Analysis of Hemoglobin A1c as a Risk Factor for Coronary Artery Disease

    Mendelian Randomization Analysis of Hemoglobin A1c as a Risk Factor for Coronary Artery Disease Autor Aaron Leong, Chen Ji, Eleanor Wheeler, Marie‐France Hivert, Yongmei Liu, Jordi Merino, Josée Dupuis, E Shyong Tai, Jerome I. Rotter, José C. Florez, Inês Barroso, James B. Meigs

    Vydáno 2019
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  9. 9
    Genetic architecture of human thinness compared to severe obesity

    Genetic architecture of human thinness compared to severe obesity Autor Fernando Riveros-Mckay, Vanisha Mistry, Rebecca Bounds, Audrey E. Hendricks, Julia M. Keogh, H. Thomas, Elana Henning, Laura J. Corbin, Stephen O’Rahilly, Eleftheria Zeggini, Eleanor Wheeler, Inês Barroso, I. Sadaf Farooqi

    Vydáno 2019
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  10. 10
    Damaging missense variants in IGF1R implicate a role for IGF-1 resistance in the etiology of type 2 diabetes

    Damaging missense variants in IGF1R implicate a role for IGF-1 resistance in the etiology of type 2 diabetes Autor Eugene J. Gardner, Katherine A. Kentistou, Stasa Stankovic, Sam Lockhart, Eleanor Wheeler, Felix R. Day, Nicola D. Kerrison, Nicholas J. Wareham, Claudia Langenberg, Stephen O’Rahilly, Ken K. Ong, John R. B. Perry

    Vydáno 2022
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  11. 11
    GIGYF1 loss of function is associated with clonal mosaicism and adverse metabolic health

    GIGYF1 loss of function is associated with clonal mosaicism and adverse metabolic health Autor Yajie Zhao, Stasa Stankovic, Mine Koprulu, Eleanor Wheeler, Felix R. Day, Hana Lango Allen, Nicola D. Kerrison, Maik Pietzner, Po‐Ru Loh, Nicholas J. Wareham, Claudia Langenberg, Ken K. Ong, John R. B. Perry

    Vydáno 2021
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  12. 12
    Mapping the serum proteome to neurological diseases using whole genome sequencing

    Mapping the serum proteome to neurological diseases using whole genome sequencing Autor Grace Png, Andrei Barysenka, L. Repetto, Pau Navarro, Xia Shen, Maik Pietzner, Eleanor Wheeler, Nicholas J. Wareham, Claudia Langenberg, Emmanouil Tsafantakis, Maria Karaleftheri, George Dedoussis, Anders Mälarstig, James F. Wilson, Arthur Gilly, Eleftheria Zeggini

    Vydáno 2021
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  13. 13
    Proteomic signatures for identification of impaired glucose tolerance

    Proteomic signatures for identification of impaired glucose tolerance Autor Julia Carrasco-Zanini, Maik Pietzner, Joni V. Lindbohm, Eleanor Wheeler, Erin Oerton, Nicola D. Kerrison, Missy Simpson, Matthew J. Westacott, D. Drolet, Mika Kivimäki, Rachel Ostroff, Stephen A. Williams, Nicholas J. Wareham, Claudia Langenberg

    Vydáno 2022
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  14. 14
    Common Variants at 10 Genomic Loci Influence Hemoglobin A1C Levels via Glycemic and Nonglycemic Pathways

    Common Variants at 10 Genomic Loci Influence Hemoglobin A1C Levels via Glycemic and Nonglycemic Pathways Autor Nicole Soranzo, Serena Sanna, Eleanor Wheeler, Christian Gieger, Dörte Radke, Josée Dupuis, Nabila Bouatia‐Naji, Claudia Langenberg, Inga Prokopenko, Man Li, Manjinder S. Sandhu, Matthew M. Heeney, Joseph M. Devaney, Muredach P. Reilly, Sally L. Ricketts

    Vydáno 2010
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  15. 15
    Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity

    Genome-wide SNP and CNV analysis identifies common and low-frequency variants associated with severe early-onset obesity Autor Eleanor Wheeler, Ni Huang, Elena G. Bochukova, Julia M. Keogh, Sarah Lindsay, Sumedha Garg, Elana Henning, Hannah Blackburn, Ruth J. F. Loos, Nicholas J. Wareham, Stephen O’Rahilly, Matthew E. Hurles, Inês Barroso, I. Sadaf Farooqi

    Vydáno 2013
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  16. 16
    Hypomorphism in human NSMCE2 linked to primordial dwarfism and insulin resistance

    Hypomorphism in human NSMCE2 linked to primordial dwarfism and insulin resistance Autor Felicity Payne, Rita Colnaghi, Nuno Rocha, Asha Seth, J. Ieuan Harris, Gillian Carpenter, William Bottomley, Eleanor Wheeler, Stephen Q. Wong, Vladimı́r Saudek, David B. Savage, Stephen O’Rahilly, Jean‐Claude Carel, Inês Barroso, Mark O’Driscoll, Robert K. Semple

    Vydáno 2014
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  17. 17
    Disease prediction with multi-omics and biomarkers empowers case–control genetic discoveries in the UK Biobank

    Disease prediction with multi-omics and biomarkers empowers case–control genetic discoveries in the UK Biobank Autor Manik Garg, Marcin Karpiński, Dorota Matelska, Lawrence Middleton, Oliver S. Burren, Fengyuan Hu, Eleanor Wheeler, Katherine R. Smith, Margarete A. Fabre, Jonathan Mitchell, Amanda O’Neill, Euan A. Ashley, Andrew R. Harper, Quanli Wang, Ryan S. Dhindsa, Slavé Petrovski, Dimitrios Vitsios

    Vydáno 2024
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  18. 18
    Genome-wide association study of type 2 diabetes in Africa

    Genome-wide association study of type 2 diabetes in Africa Autor Chen Ji, Meng Sun, Adebowale Adeyemo, Fraser Pirie, Tommy Carstensen, Cristina Pomilla, Ayo P. Doumatey, Guanjie Chen, Elizabeth Young, Manjinder S. Sandhu, Andrew P. Morris, Inês Barroso, Mark I. McCarthy, Anubha Mahajan, Eleanor Wheeler, Charles N. Rotimi, Ayesha A. Motala

    Vydáno 2019
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  19. 19
    Genetic architecture of host proteins involved in SARS-CoV-2 infection

    Genetic architecture of host proteins involved in SARS-CoV-2 infection Autor Maik Pietzner, Eleanor Wheeler, Julia Carrasco-Zanini, Johannes Raffler, Nicola D. Kerrison, Erin Oerton, Victoria P.W. Auyeung, Jian’an Luan, Chris Finan, Juan P. Casas, Rachel Ostroff, Stephen A. Williams, Gabi Kastenmüller, Markus Ralser, Eric R. Gamazon, Nicholas J. Wareham, Aroon D. Hingorani, Claudia Langenberg

    Vydáno 2020
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  20. 20
    ELF5 is a potential respiratory epithelial cell-specific risk gene for severe COVID-19

    ELF5 is a potential respiratory epithelial cell-specific risk gene for severe COVID-19 Autor Maik Pietzner, Robert Lorenz Chua, Eleanor Wheeler, Katharina Jechow, Julian Daniel Sunday Willett, Helena Radbruch, Saskia Trump, Bettina Heidecker, Hugo Zeberg, Frank L. Heppner, Roland Eils, Marcus Mall, J. Brent Richards, Leif Erik Sander, Irina Lehmann, Soeren Lukassen, Nicholas J. Wareham, Christian Conrad, Claudia Langenberg

    Vydáno 2022
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