Risultati della ricerca - Edward W. Tate

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  1. 1
    <i>N</i>-Myristoylation as a Drug Target in Malaria: Exploring the Role of <i>N</i>-Myristoyltransferase Substrates in the Inhibitor Mode of Action

    <i>N</i>-Myristoylation as a Drug Target in Malaria: Exploring the Role of <i>N</i>-Myristoyltransferase Substrates in the Inhibitor Mode of Action di Anja Schlott, Anthony A. Holder, Edward W. Tate

    Pubblicazione 2018
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  2. 2
    UCHL1 as a novel target in breast cancer: emerging insights from cell and chemical biology

    UCHL1 as a novel target in breast cancer: emerging insights from cell and chemical biology di Milon Mondal, Daniel Conole, Jaya Nautiyal, Edward W. Tate

    Pubblicazione 2021
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  3. 3
    Demographic, Clinical, and Immunologic Features of 389 Children with Opsoclonus-Myoclonus Syndrome: A Cross-sectional Study

    Demographic, Clinical, and Immunologic Features of 389 Children with Opsoclonus-Myoclonus Syndrome: A Cross-sectional Study di Michael R. Pranzatelli, Edward W. Tate, Nathan R. McGee

    Pubblicazione 2017
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  4. 4
    Chemical and biomimetic total syntheses of natural and engineered MCoTI cyclotides

    Chemical and biomimetic total syntheses of natural and engineered MCoTI cyclotides di Panumart Thongyoo, Núria Roqué-Rosell, Robin J. Leatherbarrow, Edward W. Tate

    Pubblicazione 2008
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  5. 5
    <i>N-</i>Myristoyltransferase as a potential drug target in malaria and leishmaniasis

    <i>N-</i>Myristoyltransferase as a potential drug target in malaria and leishmaniasis di Edward W. Tate, Andrew Bell, M.D. Rackham, Megan H. Wright

    Pubblicazione 2013
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  6. 6
    <i>N</i>-Myristoyltransferase Inhibition Induces ER-Stress, Cell Cycle Arrest, and Apoptosis in Cancer Cells

    <i>N</i>-Myristoyltransferase Inhibition Induces ER-Stress, Cell Cycle Arrest, and Apoptosis in Cancer Cells di Emmanuelle Thinon, Julia Morales‐Sanfrutos, David J. Mann, Edward W. Tate

    Pubblicazione 2016
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  7. 7
    Protein myristoylation in health and disease

    Protein myristoylation in health and disease di Megan H. Wright, William P. Heal, David J. Mann, Edward W. Tate

    Pubblicazione 2009
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  8. 8
    Protein multi-scale organization through graph partitioning and robustness analysis: application to the myosin–myosin light chain interaction

    Protein multi-scale organization through graph partitioning and robustness analysis: application to the myosin–myosin light chain interaction di Antoine Pierre Valere Delmotte, Edward W. Tate, Sophia N. Yaliraki, Mauricio Barahona

    Pubblicazione 2011
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  9. 9
    Discovery of potent and selective activity-based probes (ABPs) for the deubiquitinating enzyme USP30

    Discovery of potent and selective activity-based probes (ABPs) for the deubiquitinating enzyme USP30 di Milon Mondal, Fangyuan Cao, Daniel Conole, Holger W. Auner, Edward W. Tate

    Pubblicazione 2024
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  10. 10
    Systems Analysis of Protein Fatty Acylation in Herpes Simplex Virus-Infected Cells Using Chemical Proteomics

    Systems Analysis of Protein Fatty Acylation in Herpes Simplex Virus-Infected Cells Using Chemical Proteomics di Remigiusz A. Serwa, Fernando Abaitua, Eberhard Krause, Edward W. Tate, Peter O’Hare

    Pubblicazione 2015
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  11. 11
    Roles of Cysteine Proteases Cwp84 and Cwp13 in Biogenesis of the Cell Wall of Clostridium difficile

    Roles of Cysteine Proteases Cwp84 and Cwp13 in Biogenesis of the Cell Wall of Clostridium difficile di Lucía de la Riva, Stephanie E. Willing, Edward W. Tate, Neil F. Fairweather

    Pubblicazione 2011
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  12. 12
    Comparing experimental and computational alanine scanning techniques for probing a prototypical protein–protein interaction

    Comparing experimental and computational alanine scanning techniques for probing a prototypical protein–protein interaction di Richard T. Bradshaw, Bhavesh Patel, Edward W. Tate, Robin J. Leatherbarrow, Ian R. Gould

    Pubblicazione 2010
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  13. 13
    Global Profiling of Huntingtin-associated protein E (HYPE)-Mediated AMPylation through a Chemical Proteomic Approach

    Global Profiling of Huntingtin-associated protein E (HYPE)-Mediated AMPylation through a Chemical Proteomic Approach di Malgorzata Broncel, Remigiusz A. Serwa, Tom D. Bunney, Matilda Katan, Edward W. Tate

    Pubblicazione 2015
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  14. 14
    Global Profiling and Inhibition of Protein Lipidation in Vector and Host Stages of the Sleeping Sickness Parasite <i>Trypanosoma brucei</i>

    Global Profiling and Inhibition of Protein Lipidation in Vector and Host Stages of the Sleeping Sickness Parasite <i>Trypanosoma brucei</i> di Megan H. Wright, Daniel Paape, Helen P. Price, Deborah F. Smith, Edward W. Tate

    Pubblicazione 2016
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  15. 15
    Crystal Structure of the Human, FIC-Domain Containing Protein HYPE and Implications for Its Functions

    Crystal Structure of the Human, FIC-Domain Containing Protein HYPE and Implications for Its Functions di Tom D. Bunney, A.R. Cole, Malgorzata Broncel, Diego Esposito, Edward W. Tate, Matilda Katan

    Pubblicazione 2014
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  16. 16
    Global Analysis of Protein N-Myristoylation and Exploration of N-Myristoyltransferase as a Drug Target in the Neglected Human Pathogen Leishmania donovani

    Global Analysis of Protein N-Myristoylation and Exploration of N-Myristoyltransferase as a Drug Target in the Neglected Human Pathogen Leishmania donovani di Megan H. Wright, Daniel Paape, Elisabeth M. Storck, Remigiusz A. Serwa, Deborah F. Smith, Edward W. Tate

    Pubblicazione 2015
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  17. 17
    Antibody–PROTAC Conjugates Enable HER2-Dependent Targeted Protein Degradation of BRD4

    Antibody–PROTAC Conjugates Enable HER2-Dependent Targeted Protein Degradation of BRD4 di Marı́a Maneiro, Nafsika Forte, Maria M. Shchepinova, Cyrille S. Kounde, Vijay Chudasama, James R. Baker, Edward W. Tate

    Pubblicazione 2020
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  18. 18
    Topological Analysis of Hedgehog Acyltransferase, a Multipalmitoylated Transmembrane Protein

    Topological Analysis of Hedgehog Acyltransferase, a Multipalmitoylated Transmembrane Protein di Antonio D. Konitsiotis, Biljana Jovanović, Paulina Ciepla, Martin Spitaler, Thomas Lanyon‐Hogg, Edward W. Tate, Anthony I. Magee

    Pubblicazione 2014
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  19. 19
    Legionella pneumophila Effector LpdA Is a Palmitoylated Phospholipase D Virulence Factor

    Legionella pneumophila Effector LpdA Is a Palmitoylated Phospholipase D Virulence Factor di Gunnar N. Schroeder, Philipp Auraß, Clare V. Oates, Edward W. Tate, Elizabeth L. Hartland, Antje Flieger, Gad Frankel

    Pubblicazione 2015
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  20. 20
    A Probe for NLRP3 Inflammasome Inhibitor MCC950 Identifies Carbonic Anhydrase 2 as a Novel Target

    A Probe for NLRP3 Inflammasome Inhibitor MCC950 Identifies Carbonic Anhydrase 2 as a Novel Target di Cassandra R. Kennedy, Andrea Goya Grocin, Tristan Kovačič, Ravi Singh, Jennifer Ward, Avinash R. Shenoy, Edward W. Tate

    Pubblicazione 2021
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