Canlyniadau Chwilio - Duncan Sproul

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  1. 1
    Genomic insights into cancer-associated aberrant CpG island hypermethylation

    Genomic insights into cancer-associated aberrant CpG island hypermethylation gan Duncan Sproul, Richard R. Meehan

    Cyhoeddwyd 2013
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  2. 2
    Analysis of Active and Inactive X Chromosome Architecture Reveals the Independent Organization of 30 nm and Large-Scale Chromatin Structures

    Analysis of Active and Inactive X Chromosome Architecture Reveals the Independent Organization of 30 nm and Large-Scale Chromatin Structures gan Catherine Naughton, Duncan Sproul, Charlotte Hamilton, Nick Gilbert

    Cyhoeddwyd 2010
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  3. 3
    Transcription factor binding predicts histone modifications in human cell lines

    Transcription factor binding predicts histone modifications in human cell lines gan Dan Benveniste, Hans-Joachim Sonntag, Guido Sanguinetti, Duncan Sproul

    Cyhoeddwyd 2014
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  4. 4
    Estrogen-induced chromatin decondensation and nuclear re-organization linked to regional epigenetic regulation in breast cancer

    Estrogen-induced chromatin decondensation and nuclear re-organization linked to regional epigenetic regulation in breast cancer gan Sehrish Rafique, Jeremy Thomas, Duncan Sproul, Wendy A. Bickmore

    Cyhoeddwyd 2015
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  5. 5
    Adenosine deaminases acting on RNA (ADARs): RNA-editing enzymes.

    Adenosine deaminases acting on RNA (ADARs): RNA-editing enzymes. gan Liam P. Keegan, Anne Leroy, Duncan Sproul, Mary A. O’Connell

    Cyhoeddwyd 2004
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  6. 6
    Targeting of Rac GTPases blocks the spread of intact human breast cancer

    Targeting of Rac GTPases blocks the spread of intact human breast cancer gan Elad Katz, Andrew H. Sims, Duncan Sproul, Helen Caldwell, J. Michael Dixon, Richard R. Meehan, David J. Harrison

    Cyhoeddwyd 2012
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  7. 7
    Recruitment to the Nuclear Periphery Can Alter Expression of Genes in Human Cells

    Recruitment to the Nuclear Periphery Can Alter Expression of Genes in Human Cells gan Lee Finlan, Duncan Sproul, Inga Thomson, Shelagh Boyle, Elizabeth Kerr, Paul Perry, Bauke Ylstra, Jonathan R. Chubb, Wendy A. Bickmore

    Cyhoeddwyd 2008
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  8. 8
    Tissue of origin determines cancer-associated CpG island promoter hypermethylation patterns

    Tissue of origin determines cancer-associated CpG island promoter hypermethylation patterns gan Duncan Sproul, Robert R. Kitchen, Colm E. Nestor, J. Michael Dixon, Andrew H. Sims, David J. Harrison, Bernard Ramsahoye, Richard R. Meehan

    Cyhoeddwyd 2012
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  9. 9
    Transcriptionally repressed genes become aberrantly methylated and distinguish tumors of different lineages in breast cancer

    Transcriptionally repressed genes become aberrantly methylated and distinguish tumors of different lineages in breast cancer gan Duncan Sproul, Colm E. Nestor, Jayne Culley, Jacqueline Dickson, J. Michael Dixon, David J. Harrison, Richard R. Meehan, Andrew H. Sims, Bernard Ramsahoye

    Cyhoeddwyd 2011
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  10. 10
    Ring1B Compacts Chromatin Structure and Represses Gene Expression Independent of Histone Ubiquitination

    Ring1B Compacts Chromatin Structure and Represses Gene Expression Independent of Histone Ubiquitination gan Ragnhild Eskeland, Martin Leeb, Graeme R. Grimes, Clémence Kress, Shelagh Boyle, Duncan Sproul, Nick Gilbert, Yuhong Fan, Arthur I. Skoultchi, Anton Wutz, Wendy A. Bickmore

    Cyhoeddwyd 2010
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  11. 11
    Lactate, a product of glycolytic metabolism, inhibits histone deacetylase activity and promotes changes in gene expression

    Lactate, a product of glycolytic metabolism, inhibits histone deacetylase activity and promotes changes in gene expression gan Tom Latham, C. Logan Mackay, Duncan Sproul, Muhammed Karim, Jayne Culley, David J. Harrison, Larry Hayward, Pat R. R. Langridge‐Smith, Nick Gilbert, Bernard Ramsahoye

    Cyhoeddwyd 2012
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  12. 12
    Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes

    Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes gan Colm E. Nestor, Raffaele Ottaviano, James P. Reddington, Duncan Sproul, Diana Reinhardt, Donncha S. Dunican, Elad Katz, J. Michael Dixon, David J. Harrison, Richard R. Meehan

    Cyhoeddwyd 2011
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  13. 13
    Genotype effects contribute to variation in longitudinal methylome patterns in older people

    Genotype effects contribute to variation in longitudinal methylome patterns in older people gan Qian Zhang, Riccardo E. Marioni, Matthew R. Robinson, Jonathan Higham, Duncan Sproul, Naomi R. Wray, Ian J. Deary, Allan F. McRae, Peter M. Visscher

    Cyhoeddwyd 2018
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  14. 14
    Age-related clonal haemopoiesis is associated with increased epigenetic age

    Age-related clonal haemopoiesis is associated with increased epigenetic age gan Neil Robertson, Robert F. Hillary, Daniel L. McCartney, Maria Terradas-Terradas, Jonathan Higham, Duncan Sproul, Ian J. Deary, Kristina Kirschner, Riccardo E. Marioni, Tamir Chandra

    Cyhoeddwyd 2019
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  15. 15
    De novo DNA methyltransferase activity in colorectal cancer is directed towards H3K36me3 marked CpG islands

    De novo DNA methyltransferase activity in colorectal cancer is directed towards H3K36me3 marked CpG islands gan Roza H. Ali Masalmeh, Francesca Taglini, Cristina Rubio-Ramon, Kamila Irena Musialik, Jonathan Higham, Hazel Davidson‐Smith, Ioannis Kafetzopoulos, Kamila Pawlicka, Hannah Finan, Richard Clark, Jimi Wills, Andrew J. Finch, Lee Murphy, Duncan Sproul

    Cyhoeddwyd 2021
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  16. 16
    Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions

    Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions gan John Cole, Neil Robertson, Mohammed Rather, John P. Thomson, Tony McBryan, Duncan Sproul, Tina Wang, Claire Brock, William Clark, Trey Ideker, Richard R. Meehan, Richard A. Miller, Holly M. Brown‐Borg, Peter D. Adams

    Cyhoeddwyd 2017
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  17. 17
    Elevated FOXG1 and SOX2 in glioblastoma enforces neural stem cell identity through transcriptional control of cell cycle and epigenetic regulators

    Elevated FOXG1 and SOX2 in glioblastoma enforces neural stem cell identity through transcriptional control of cell cycle and epigenetic regulators gan Harry Bulstrode, Ewan Johnstone, María Ángeles Marqués‐Torrejón, Kirsty M. Ferguson, Raul Bardini Bressan, Carla Blin, Vivien Grant, Sabine Gogolok, Ester Gangoso, Sladjana Gagrica, Christine Ender, Vassiliki Fotaki, Duncan Sproul, Paul Bertone, Steven M. Pollard

    Cyhoeddwyd 2017
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  18. 18
    DNMT3B PWWP mutations cause hypermethylation of heterochromatin

    DNMT3B PWWP mutations cause hypermethylation of heterochromatin gan Francesca Taglini, Ioannis Kafetzopoulos, Willow Rolls, Kamila Irena Musialik, Heng Yang Lee, Yujie Zhang, Mattia Marenda, Lyndsay Kerr, Hannah Finan, Cristina Rubio-Ramon, Philippe Gautier, Hannah Wapenaar, Dhananjay Kumar, Hazel Davidson‐Smith, Jimi Wills, Laura C. Murphy, Ann Wheeler, Marcus D. Wilson, Duncan Sproul

    Cyhoeddwyd 2024
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  19. 19
    Gain-of-function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions

    Gain-of-function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions gan Patricia Heyn, Clare V. Logan, Adeline Fluteau, Rachel Challis, Tatsiana Auchynnikava, Carol-Anne Martin, Joseph A. Marsh, Francesca Taglini, Fiona Kilanowski, David Parry, Valérie Cormier‐Daire, Chin‐To Fong, Kate Gibson, Vivian Hwa, Lourdes Ibáñez, Stephen P. Robertson, Giorgia Sebastiani, Juri Rappsilber, Robin C. Allshire, Martin A.M. Reijns, Andrew Dauber, Duncan Sproul, Andrew P. Jackson

    Cyhoeddwyd 2018
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  20. 20
    Parent of origin genetic effects on methylation in humans are common and influence complex trait variation

    Parent of origin genetic effects on methylation in humans are common and influence complex trait variation gan Yanni Zeng, Carmen Amador, Charley Xia, Riccardo E. Marioni, Duncan Sproul, Rosie M. Walker, Stewart W. Morris, Andrew D. Bretherick, Oriol Canela‐Xandri, Thibaud Boutin, David W. Clark, Archie Campbell, Konrad Rawlik, Caroline Hayward, Réka Nagy, Albert Tenesa, David J. Porteous, James F. Wilson, Ian J. Deary, Kathryn L. Evans, Andrew M. McIntosh, Pau Navarro, Chris Haley

    Cyhoeddwyd 2019
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