Search Results - Duncan L. Smith

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  1. 1
    Mitochondria as new therapeutic targets for eradicating cancer stem cells: Quantitative proteomics and functional validation via MCT1/2 inhibition

    Mitochondria as new therapeutic targets for eradicating cancer stem cells: Quantitative proteomics and functional validation via MCT1/2 inhibition by Rebecca Lamb, Hannah Harrison, James Hulit, Duncan L. Smith, Michael P. Lisanti, Federica Sotgia

    Published 2014
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  2. 2
    A global non-coding RNA system modulates fission yeast protein levels in response to stress

    A global non-coding RNA system modulates fission yeast protein levels in response to stress by Hui Sun Leong, Keren Dawson, Christopher Wirth, Yaoyong Li, Yvonne Connolly, Duncan L. Smith, Caroline R.M. Wilkinson, Crispin Miller

    Published 2014
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  3. 3
    A PP1–PP2A phosphatase relay controls mitotic progression

    A PP1–PP2A phosphatase relay controls mitotic progression by Ágnes Grallert, Elvan Böke, Anja Hagting, Ben Hodgson, Yvonne Connolly, John R. Griffiths, Duncan L. Smith, Jonathon Pines, Iain Hagan

    Published 2014
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  4. 4
    Proteomic Plasma Membrane Profiling Reveals an Essential Role for gp96 in the Cell Surface Expression of LDLR Family Members, Including the LDL Receptor and LRP6

    Proteomic Plasma Membrane Profiling Reveals an Essential Role for gp96 in the Cell Surface Expression of LDLR Family Members, Including the LDL Receptor and LRP6 by Michael P. Weekes, Robin Antrobus, Suzanne Talbot, Simon Hör, Nikol Simecek, Duncan L. Smith, Stuart Bloor, Felix Randow, Paul J. Lehner

    Published 2012
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  5. 5
    HUWE1 Ubiquitylates and Degrades the RAC Activator TIAM1 Promoting Cell-Cell Adhesion Disassembly, Migration, and Invasion

    HUWE1 Ubiquitylates and Degrades the RAC Activator TIAM1 Promoting Cell-Cell Adhesion Disassembly, Migration, and Invasion by Lynsey Vaughan, Chong Teik Tan, Anna Chapman, Daisuke Nonaka, Natalie A. Mack, Duncan L. Smith, Richard Booton, Adam Hurlstone, Angeliki Malliri

    Published 2014
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  6. 6
    Dissecting tumor metabolic heterogeneity: Telomerase and large cell size metabolically define a sub-population of stem-like, mitochondrial-rich, cancer cells

    Dissecting tumor metabolic heterogeneity: Telomerase and large cell size metabolically define a sub-population of stem-like, mitochondrial-rich, cancer cells by Rebecca Lamb, Béla Ózsvári, Gloria Bonuccelli, Duncan L. Smith, Richard G. Pestell, Ubaldo Martinez‐Outschoorn, Robert B. Clarke, Federica Sotgia, Michael P. Lisanti

    Published 2015
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  7. 7
    Latency-Associated Degradation of the MRP1 Drug Transporter During Latent Human Cytomegalovirus Infection

    Latency-Associated Degradation of the MRP1 Drug Transporter During Latent Human Cytomegalovirus Infection by Michael P. Weekes, Shireen Yan Ling Tan, Emma Poole, Suzanne Talbot, Robin Antrobus, Duncan L. Smith, Christina Montag, Steven P. Gygi, John Sinclair, Paul J. Lehner

    Published 2013
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  8. 8
    Targeting tumor-initiating cells: Eliminating anabolic cancer stem cells with inhibitors of protein synthesis or by mimicking caloric restriction

    Targeting tumor-initiating cells: Eliminating anabolic cancer stem cells with inhibitors of protein synthesis or by mimicking caloric restriction by Rebecca Lamb, Hannah Harrison, Duncan L. Smith, Paul A. Townsend, Thomas Jackson, Béla Ózsvári, Ubaldo Martinez‐Outschoorn, Richard G. Pestell, Anthony Howell, Michael P. Lisanti, Federica Sotgia

    Published 2015
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  9. 9
    Quantitative Proteomics Analysis Demonstrates Post-transcriptional Regulation of Embryonic Stem Cell Differentiation to Hematopoiesis

    Quantitative Proteomics Analysis Demonstrates Post-transcriptional Regulation of Embryonic Stem Cell Differentiation to Hematopoiesis by Andrew J.K. Williamson, Duncan L. Smith, David Blinco, Richard D. Unwin, Stella Pearson, Claire Wilson, Crispin Miller, Lee Lancashire, Georges Lacaud, Valérie Kouskoff, Anthony D. Whetton

    Published 2007
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  10. 10
    Human Cytomegalovirus Infection Upregulates the Mitochondrial Transcription and Translation Machineries

    Human Cytomegalovirus Infection Upregulates the Mitochondrial Transcription and Translation Machineries by Sharon Karniely, Michael P. Weekes, Robin Antrobus, Joanna Rorbach, Lindsey Van Haute, Yagnesh Umrania, Duncan L. Smith, Richard J. Stanton, Michal Minczuk, Paul J. Lehner, John Sinclair

    Published 2016
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  11. 11
    Mitochondrial biogenesis is required for the anchorage-independent survival and propagation of stem-like cancer cells

    Mitochondrial biogenesis is required for the anchorage-independent survival and propagation of stem-like cancer cells by Arianna De Luca, Marco Fiorillo, Maria Peiris‐Pagès, Béla Ózsvári, Duncan L. Smith, Rosa Sánchez‐Alvarez, Ubaldo Martinez‐Outschoorn, Anna Rita Cappello, Vincenzo Pezzi, Michael P. Lisanti, Federica Sotgia

    Published 2015
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  12. 12
    Cleavage by signal peptide peptidase is required for the degradation of selected tail-anchored proteins

    Cleavage by signal peptide peptidase is required for the degradation of selected tail-anchored proteins by Jessica M. Boname, Stuart Bloor, Michal P. Wandel, James A. Nathan, Robin Antrobus, Kevin S. Dingwell, Teresa L. M. Thurston, Duncan L. Smith, James C. Smith, Felix Randow, Paul J. Lehner

    Published 2014
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  13. 13
    Lysyl oxidase drives tumour progression by trapping EGF receptors at the cell surface

    Lysyl oxidase drives tumour progression by trapping EGF receptors at the cell surface by Haoran Tang, Leo Leung, Grazia Saturno, Amaya Virós, Duncan L. Smith, Gianpiero Di Leva, Eamonn Morrison, Dan Niculescu‐Duvaz, Filipa Lopes, Louise D. Johnson, Nathalie Dhomen, Caroline J. Springer, Richard Marais

    Published 2017
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  14. 14
    Doxycycline down-regulates DNA-PK and radiosensitizes tumor initiating cells: Implications for more effective radiation therapy

    Doxycycline down-regulates DNA-PK and radiosensitizes tumor initiating cells: Implications for more effective radiation therapy by Rebecca Lamb, Marco Fiorillo, Amy L. Chadwick, Béla Ózsvári, Kimberly J. Reeves, Duncan L. Smith, Robert B. Clarke, Sacha J. Howell, Anna Rita Cappello, Ubaldo Martinez‐Outschoorn, Maria Peiris‐Pagès, Federica Sotgia, Michael P. Lisanti

    Published 2015
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  15. 15
    Mitochondrial mass, a new metabolic biomarker for stem-like cancer cells: Understanding WNT/FGF-driven anabolic signaling

    Mitochondrial mass, a new metabolic biomarker for stem-like cancer cells: Understanding WNT/FGF-driven anabolic signaling by Rebecca Lamb, Gloria Bonuccelli, Béla Ózsvári, Maria Peiris‐Pagès, Marco Fiorillo, Duncan L. Smith, Generoso Bevilacqua, Chiara Maria Mazzanti, Liam A. McDonnell, Antonio Giuseppe Naccarato, Maybo Chiu, Luke Wynne, Ubaldo Martinez‐Outschoorn, Federica Sotgia, Michael P. Lisanti

    Published 2015
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  16. 16
    Site-selective photo-crosslinking for the characterisation of transient ubiquitin-like protein-protein interactions

    Site-selective photo-crosslinking for the characterisation of transient ubiquitin-like protein-protein interactions by Zac Sandy, Zijuan Wang, Deepak Behera, Benjamin M. Foster, Francisco Martı́n, Kira Brüninghoff, Kathleen Cain, Wolfgang Dörner, María J. Cabello-Lobato, Josep V. Forment, Matthew J. Cliff, Igor Larrosa, Perdita E. Barran, Duncan L. Smith, Henning D. Mootz, Christine K. Schmidt

    Published 2025
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  17. 17
    RAC2, AEP, and ICAM1 expression are associated with CNS disease in a mouse model of pre-B childhood acute lymphoblastic leukemia

    RAC2, AEP, and ICAM1 expression are associated with CNS disease in a mouse model of pre-B childhood acute lymphoblastic leukemia by Mark Holland, Fernanda Castro, Seema Alexander, Duncan L. Smith, Jizhong Liu, Michael G. Walker, Danny A. Bitton, Kate Mulryan, Garry Ashton, Morgan Blaylock, Steve Bagley, Yvonne Connolly, John S. Bridgeman, Crispin Miller, Shekhar Krishnan, Clare Dempsey, Ashish Masurekar, Peter L. Stern, Anthony D. Whetton, Vaskar Saha

    Published 2011
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  18. 18
    Enhancer Activation by Pharmacologic Displacement of LSD1 from GFI1 Induces Differentiation in Acute Myeloid Leukemia

    Enhancer Activation by Pharmacologic Displacement of LSD1 from GFI1 Induces Differentiation in Acute Myeloid Leukemia by Alba Maiqués-Díaz, Gary J. Spencer, James T. Lynch, Filippo Ciceri, Emma L. Williams, Fabio M. R. Amaral, Daniel H. Wiseman, William J. Harris, Yaoyong Li, Sudhakar Sahoo, James R. Hitchin, Daniel P. Mould, Emma Fairweather, Bohdan Waszkowycz, Allan M. Jordan, Duncan L. Smith, Tim C. P. Somervaille

    Published 2018
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  19. 19
    Stromal lipid species dictate melanoma metastasis and tropism

    Stromal lipid species dictate melanoma metastasis and tropism by Shilpa Gurung, Timothy Budden, Karthik Mallela, Benjamin H. Jenkins, Alex von Kriegsheim, Esperanza Manrique, David Millán-Esteban, Isabel Romero-Camarero, Fabio M. R. Amaral, Sarah Craig, Pedro Miguel Carvalho Durão, Joanna Poźniak, Laura Stennett, Duncan L. Smith, Garry Ashton, Alex R. Baker, Kang Zeng, Gilbert O. Fruhwirth, Victoria Sanz‐Moreno, Jair Marques, Albert Koulman, Jean‐Christophe Marine, Tim C. P. Somervaille, Luisa Motta, C. Gaudy‐Marqueste, Eduardo Nagore, Amaya Virós

    Published 2025
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  20. 20
    A microenvironment-inspired synthetic three-dimensional model for pancreatic ductal adenocarcinoma organoids

    A microenvironment-inspired synthetic three-dimensional model for pancreatic ductal adenocarcinoma organoids by Christopher Below, Joanna Kelly, Alexander Brown, Jonathan D. Humphries, Colin Hutton, Jingshu Xu, Brian Y. Lee, Célia Cintas, Xiaohong Zhang, Victor Hernandez‐Gordillo, Linda Stockdale, Matthew A. Goldsworthy, Joe Geraghty, Lucy Foster, Derek O’Reilly, Barbara Schedding, Janet A. Askari, Jessica Burns, Nigel W. Hodson, Duncan L. Smith, Catherine Lally, Garry Ashton, David Knight, Mironov Aa, Antonia Banyard, Johannes A. Eble, Jennifer P. Morton, Martin J. Humphries, Linda G. Griffith, Claus Jørgensen

    Published 2021
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