Результати пошуку - Duncan I. Jodrell

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  1. 1
    Anti-Tumour Effects of a Specific Anti-ADAM17 Antibody in an Ovarian Cancer Model In Vivo

    Anti-Tumour Effects of a Specific Anti-ADAM17 Antibody in an Ovarian Cancer Model In Vivo за авторством Frances M. Richards, Christopher J. Tape, Duncan I. Jodrell, Gillian Murphy

    Опубліковано 2012
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  2. 2
    GEMMs as preclinical models for testing pancreatic cancer therapies

    GEMMs as preclinical models for testing pancreatic cancer therapies за авторством Aarthi Gopinathan, Jennifer P. Morton, Duncan I. Jodrell, Owen J. Sansom

    Опубліковано 2015
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  3. 3
    Targeting of 5-aza-2′-deoxycytidine residues by chromatin-associated DNMT1 induces proteasomal degradation of the free enzyme

    Targeting of 5-aza-2′-deoxycytidine residues by chromatin-associated DNMT1 induces proteasomal degradation of the free enzyme за авторством Katan I. Patel, Jacqueline Dickson, Shikuan Din, Kenneth M. MacLeod, Duncan I. Jodrell, Bernard Ramsahoye

    Опубліковано 2010
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  4. 4
    Enhanced oxaliplatin-induced apoptosis following antisense Bcl-xl down-regulation is p53 and Bax dependent: Genetic evidence for specificity of the antisense effect

    Enhanced oxaliplatin-induced apoptosis following antisense Bcl-xl down-regulation is p53 and Bax dependent: Genetic evidence for specificity of the antisense effect за авторством Richard L. Hayward, Janet S. Macpherson, Jeff Cummings, Brett P. Monia, John F. Smyth, Duncan I. Jodrell

    Опубліковано 2004
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  5. 5
    A quantitative FastFUCCI assay defines cell cycle dynamics at a single-cell level

    A quantitative FastFUCCI assay defines cell cycle dynamics at a single-cell level за авторством Siang‐Boon Koh, Patrice Mascalchi, Esther Rodríguez, Yao Lin, Duncan I. Jodrell, Frances M. Richards, Scott K. Lyons

    Опубліковано 2016
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  6. 6
    <i>nab</i>-Paclitaxel Potentiates Gemcitabine Activity by Reducing Cytidine Deaminase Levels in a Mouse Model of Pancreatic Cancer

    <i>nab</i>-Paclitaxel Potentiates Gemcitabine Activity by Reducing Cytidine Deaminase Levels in a Mouse Model of Pancreatic Cancer за авторством Kristopher K. Frese, Albrecht Neeße, Natalie Cook, Tashinga E. Bapiro, Martijn P. Lolkema, Duncan I. Jodrell, David A. Tuveson

    Опубліковано 2012
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  7. 7
    Optimization of the Antitumor Activity of Sequence-specific Pyrrolobenzodiazepine Derivatives Based on their Affinity for ABC Transporters

    Optimization of the Antitumor Activity of Sequence-specific Pyrrolobenzodiazepine Derivatives Based on their Affinity for ABC Transporters за авторством Maciej Kaliszczak, Dyeison Antonow, Katan I. Patel, Philip W. Howard, Duncan I. Jodrell, David E. Thurston, Sylvie M. Guichard

    Опубліковано 2010
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  8. 8
    In vitro and in vivo activity and cross resistance profiles of novel ruthenium (II) organometallic arene complexes in human ovarian cancer

    In vitro and in vivo activity and cross resistance profiles of novel ruthenium (II) organometallic arene complexes in human ovarian cancer за авторством Rhona Aird, Jeffrey L. Cummings, Alison Ritchie, Morwenna Muir, Robert E. Morris, H Chen, Peter J. Sadler, Duncan I. Jodrell

    Опубліковано 2002
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  9. 9
    Tumor-Induced IL-6 Reprograms Host Metabolism to Suppress Anti-tumor Immunity

    Tumor-Induced IL-6 Reprograms Host Metabolism to Suppress Anti-tumor Immunity за авторством Thomas R. Flint, Tobias Janowitz, Claire M. Connell, Edward W. Roberts, Alice E. Denton, Anthony P. Coll, Duncan I. Jodrell, Douglas T. Fearon

    Опубліковано 2016
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  10. 10
    Mechanistic Distinctions between CHK1 and WEE1 Inhibition Guide the Scheduling of Triple Therapy with Gemcitabine

    Mechanistic Distinctions between CHK1 and WEE1 Inhibition Guide the Scheduling of Triple Therapy with Gemcitabine за авторством Siang‐Boon Koh, Yann Wallez, Charles R. Dunlop, Sandra Bernaldo de Quirós Fernández, Tashinga E. Bapiro, Frances M. Richards, Duncan I. Jodrell

    Опубліковано 2018
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  11. 11
    γ-H2AX Foci Formation as a Pharmacodynamic Marker of DNA Damage Produced by DNA Cross-Linking Agents: Results from 2 Phase I Clinical Trials of SJG-136 (SG2000)

    γ-H2AX Foci Formation as a Pharmacodynamic Marker of DNA Damage Produced by DNA Cross-Linking Agents: Results from 2 Phase I Clinical Trials of SJG-136 (SG2000) за авторством Jenny Wu, Peter H. Clingen, Victoria J. Spanswick, Maria Mellinas‐Gomez, Tim Meyer, Igor Puzanov, Duncan I. Jodrell, Daniel Hochhauser, John A. Hartley

    Опубліковано 2012
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  12. 12
    SPARC independent drug delivery and antitumour effects of<i>nab</i>-paclitaxel in genetically engineered mice

    SPARC independent drug delivery and antitumour effects of<i>nab</i>-paclitaxel in genetically engineered mice за авторством Albrecht Neeße, Kristopher K. Frese, Derek Chan, Tashinga E. Bapiro, William Howat, Frances M. Richards, Volker Ellenrieder, Duncan I. Jodrell, David A. Tuveson

    Опубліковано 2013
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  13. 13
    A Phase 1 Study of AS1409, a Novel Antibody-Cytokine Fusion Protein, in Patients with Malignant Melanoma or Renal Cell Carcinoma

    A Phase 1 Study of AS1409, a Novel Antibody-Cytokine Fusion Protein, in Patients with Malignant Melanoma or Renal Cell Carcinoma за авторством Sarah Maria Rudman, Michael B. Jameson, Mark J. McKeage, Philip Savage, Duncan I. Jodrell, Mark Harries, Gary D Acton, Fredrik Erlandsson, James Spicer

    Опубліковано 2011
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  14. 14
    CTGF antagonism with mAb FG-3019 enhances chemotherapy response without increasing drug delivery in murine ductal pancreas cancer

    CTGF antagonism with mAb FG-3019 enhances chemotherapy response without increasing drug delivery in murine ductal pancreas cancer за авторством Albrecht Neeße, Kristopher K. Frese, Tashinga E. Bapiro, Tomoaki Nakagawa, Mark D. Sternlicht, Todd Seeley, Christian Pilarsky, Duncan I. Jodrell, Suzanne Spong, David A. Tuveson

    Опубліковано 2013
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  15. 15
    Aspirin activates the NF- B signalling pathway and induces apoptosis in intestinal neoplasia in two in vivo models of human colorectal cancer

    Aspirin activates the NF- B signalling pathway and induces apoptosis in intestinal neoplasia in two in vivo models of human colorectal cancer за авторством Lesley A. Stark, Kenneth GC Reid, Owen J. Sansom, Farhat Din, Sylvie M. Guichard, I. Mayer, Duncan I. Jodrell, Alan R. Clarke, Malcolm G. Dunlop

    Опубліковано 2006
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  16. 16
    Complete loss of ATM function augments replication catastrophe induced by ATR inhibition and gemcitabine in pancreatic cancer models

    Complete loss of ATM function augments replication catastrophe induced by ATR inhibition and gemcitabine in pancreatic cancer models за авторством Charles R. Dunlop, Yann Wallez, Timothy Isaac Johnson, Sandra Bernaldo de Quirós Fernández, Stephen T. Durant, Elaine Cadogan, Alan Lau, Frances M. Richards, Duncan I. Jodrell

    Опубліковано 2020
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  17. 17
    A randomised comparison between 6 months of bolus fluorouracil/leucovorin and 12 weeks of protracted venous infusion fluorouracil as adjuvant treatment in colorectal cancer

    A randomised comparison between 6 months of bolus fluorouracil/leucovorin and 12 weeks of protracted venous infusion fluorouracil as adjuvant treatment in colorectal cancer за авторством Ian Chau, A. Norman, David Cunningham, Diana Tait, Paul J. Ross, Timothy Iveson, Mark Hill, Tamas Hickish, F. Lofts, Duncan I. Jodrell, Andrew Webb, J. Oates

    Опубліковано 2005
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  18. 18
    Twelve weeks of protracted venous infusion of fluorouracil (5-FU) is as effective as 6 months of bolus 5-FU and folinic acid as adjuvant treatment in colorectal cancer

    Twelve weeks of protracted venous infusion of fluorouracil (5-FU) is as effective as 6 months of bolus 5-FU and folinic acid as adjuvant treatment in colorectal cancer за авторством Andrea Saini, A. Norman, David Cunningham, Ian Chau, Mark Hill, Diana Tait, Tamas Hickish, Timothy Iveson, F. Lofts, Duncan I. Jodrell, Paul J. Ross, J. Oates

    Опубліковано 2003
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  19. 19
    Depletion of Macrophages Improves Therapeutic Response to Gemcitabine in Murine Pancreas Cancer

    Depletion of Macrophages Improves Therapeutic Response to Gemcitabine in Murine Pancreas Cancer за авторством S Buchholz, Robert G. Goetze, Shiv K. Singh, Christoph Ammer‐Herrmenau, Frances M. Richards, Duncan I. Jodrell, Malte Buchholz, Patrick Michl, Volker Ellenrieder, Elisabeth Heßmann, Albrecht Neeße

    Опубліковано 2020
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  20. 20
    Gamma secretase inhibition promotes hypoxic necrosis in mouse pancreatic ductal adenocarcinoma

    Gamma secretase inhibition promotes hypoxic necrosis in mouse pancreatic ductal adenocarcinoma за авторством Natalie Cook, Kristopher K. Frese, Tashinga E. Bapiro, Michael A. Jacobetz, Aarthi Gopinathan, Jodi L. Miller, Sudhir Rao, Tim Demuth, William Howat, Duncan I. Jodrell, David A. Tuveson

    Опубліковано 2012
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