Search Results - Drew Adams

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  1. 1
    The landscape of targets and lead molecules for remyelination

    The landscape of targets and lead molecules for remyelination by Andrew V. Caprariello, Drew Adams

    Published 2022
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  2. 2
    MM-506 Novel Proteasome Activators That Enhance MHC Class I Antigen Presentation and Trigger Anti-Myeloma T-Cell Immunity

    MM-506 Novel Proteasome Activators That Enhance MHC Class I Antigen Presentation and Trigger Anti-Myeloma T-Cell Immunity by Priyanka S. Rana, James J. Ignatz-Hoover, Ehsan Malek, James F. Driscoll, Yuriy Federov, Drew Adams

    Published 2023
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  3. 3
    Synthesis, cellular evaluation, and mechanism of action of piperlongumine analogs

    Synthesis, cellular evaluation, and mechanism of action of piperlongumine analogs by Drew Adams, Mingji Dai, Giovanni Pellegrino, Bridget K. Wagner, Andrew M. Stern, Alykhan F. Shamji, Stuart L. Schreiber

    Published 2012
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  4. 4
    Diverse Chemical Scaffolds Enhance Oligodendrocyte Formation by Inhibiting CYP51, TM7SF2, or EBP

    Diverse Chemical Scaffolds Enhance Oligodendrocyte Formation by Inhibiting CYP51, TM7SF2, or EBP by Dharmaraja Allimuthu, Zita Hubler, Fadi J. Najm, Hong Tang, Ilya Bederman, William Seibel, Paul J. Tesar, Drew Adams

    Published 2019
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  5. 5
    Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington’s disease

    Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington’s disease by Di Hu, Xiaoyan Sun, Anniefer N. Magpusao, Yuriy Fedorov, Matthew A. Thompson, Benlian Wang, Kathleen C. Lundberg, Drew Adams, Xin Qi

    Published 2021
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  6. 6
    Discovery of Small-Molecule Enhancers of Reactive Oxygen Species That are Nontoxic or Cause Genotype-Selective Cell Death

    Discovery of Small-Molecule Enhancers of Reactive Oxygen Species That are Nontoxic or Cause Genotype-Selective Cell Death by Drew Adams, Žarko Bošković, Jimmy R. Thériault, Alex J. Wang, Andrew M. Stern, Bridget K. Wagner, Alykhan F. Shamji, Stuart L. Schreiber

    Published 2013
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  7. 7
    A Small-Molecule Probe of the Histone Methyltransferase G9a Induces Cellular Senescence in Pancreatic Adenocarcinoma

    A Small-Molecule Probe of the Histone Methyltransferase G9a Induces Cellular Senescence in Pancreatic Adenocarcinoma by Yuan Yuan, Qiu Wang, Joshiawa Paulk, Stefan Kubicek, Melissa M. Kemp, Drew Adams, Alykhan F. Shamji, Bridget K. Wagner, Stuart L. Schreiber

    Published 2012
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  8. 8
    ATAD3A oligomerization promotes neuropathology and cognitive deficits in Alzheimer’s disease models

    ATAD3A oligomerization promotes neuropathology and cognitive deficits in Alzheimer’s disease models by Yuanyuan Zhao, Di Hu, Rihua Wang, Xiaoyan Sun, Philip Ropelewski, Zita Hubler, Kathleen C. Lundberg, QuanQiu Wang, Drew Adams, Rong Xu, Xin Qi

    Published 2022
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  9. 9
    NAMPT Is the Cellular Target of STF-31-Like Small-Molecule Probes

    NAMPT Is the Cellular Target of STF-31-Like Small-Molecule Probes by Drew Adams, Daisuke Ito, Matthew G. Rees, Brinton Seashore‐Ludlow, Xiaoling Puyang, Alex H. Ramos, Jaime H. Cheah, Paul A. Clemons, Markus Warmuth, Ping Zhu, Alykhan F. Shamji, Stuart L. Schreiber

    Published 2014
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  10. 10
    Ex vivo screen identifies CDK12 as a metastatic vulnerability in osteosarcoma

    Ex vivo screen identifies CDK12 as a metastatic vulnerability in osteosarcoma by Ian Bayles, Małgorzata Krajewska, William Pontius, Alina Saiakhova, James J. Morrow, Cynthia F. Bartels, Jim Lu, Zachary Faber, Yuriy Fedorov, Ellen S. Hong, Jaret M. Karnuta, Brian P. Rubin, Drew Adams, Rani E. George, Peter C. Scacheri

    Published 2019
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  11. 11
    Integrative Radiogenomic Profiling of Squamous Cell Lung Cancer

    Integrative Radiogenomic Profiling of Squamous Cell Lung Cancer by Mohamed E. Abazeed, Drew Adams, Kristen E. Hurov, Pablo Tamayo, Chad J. Creighton, Dmitriy Sonkin, Andrew O. Giacomelli, Charles Du, Daniel F. Fries, Kwok‐Kin Wong, Jill P. Mesirov, Jay S. Loeffler, Stuart L. Schreiber, Peter S. Hammerman, Matthew Meyerson

    Published 2013
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  12. 12
    Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination

    Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination by Zita Hubler, Dharmaraja Allimuthu, Ilya Bederman, Matthew S. Elitt, Mayur Madhavan, Kevin Allan, H. Elizabeth Shick, Eric Garrison, Molly Karl, Daniel C. Factor, Zachary S. Nevin, Joel L. Sax, Matthew A. Thompson, Yuriy Fedorov, Jing Jin, William K. Wilson, Martin Giera, Franz Bracher, Robert H. Miller, Paul J. Tesar, Drew Adams

    Published 2018
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  13. 13
    A genetic basis for the variation in the vulnerability of cancer to DNA damage

    A genetic basis for the variation in the vulnerability of cancer to DNA damage by Brian D. Yard, Drew Adams, Eui Kyu Chie, Pablo Tamayo, Jessica Battaglia, Priyanka Gopal, Kevin Rogacki, Bradley Pearson, James G. Phillips, Daniel P. Raymond, Nathan A. Pennell, Francisco A. Almeida, Jaime H. Cheah, Paul A. Clemons, Alykhan F. Shamji, Craig D. Peacock, Stuart L. Schreiber, Peter S. Hammerman, Mohamed E. Abazeed

    Published 2016
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  14. 14
    Melanoma Therapeutic Strategies that Select against Resistance by Exploiting MYC-Driven Evolutionary Convergence

    Melanoma Therapeutic Strategies that Select against Resistance by Exploiting MYC-Driven Evolutionary Convergence by Katherine R. Singleton, Lorin Crawford, Elizabeth Tsui, Haley E. Manchester, Ophélia Maertens, Xiaojing Liu, Maria V. Liberti, Anniefer N. Magpusao, Elizabeth M. Stein, Jennifer P. Tingley, Dennie T. Frederick, Genevieve M. Boland, Keith T. Flaherty, Shannon J. McCall, Clemens Krepler, Katrin Sproesser, Meenhard Herlyn, Drew Adams, Jason W. Locasale, Karen Cichowski, Sayan Mukherjee, Kris C. Wood

    Published 2017
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  15. 15
    Correlating chemical sensitivity and basal gene expression reveals mechanism of action

    Correlating chemical sensitivity and basal gene expression reveals mechanism of action by Matthew G. Rees, Brinton Seashore‐Ludlow, Jaime H. Cheah, Drew Adams, Edmund V. Price, Shubhroz Gill, Sarah Javaid, Matthew E. Coletti, Victor Jones, Nicole E. Bodycombe, Christian K. Soule, Benjamin Alexander, Ava Li, Philip Montgomery, Joanne Kotz, C. Suk-Yee Hon, Benito Muñoz, Ted Liefeld, Vlado Dančík, Daniel A. Haber, Clary B. Clish, Joshua A. Bittker, Michelle Palmer, Bridget K. Wagner, Paul A. Clemons, Alykhan F. Shamji, Stuart L. Schreiber

    Published 2015
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  16. 16
    Cell Type-Specific Intralocus Interactions Reveal Oligodendrocyte Mechanisms in MS

    Cell Type-Specific Intralocus Interactions Reveal Oligodendrocyte Mechanisms in MS by Daniel C. Factor, Anna M. Barbeau, Kevin Allan, Lucille R. Hu, Mayur Madhavan, An T. Hoang, Kathryn E.A. Hazel, Parker A. Hall, Sagar Nisraiyya, Fadi J. Najm, Tyler E. Miller, Zachary S. Nevin, Robert T. Karl, Bruna R. Lima, Yanwei Song, Alexandra G. Sibert, Gursimran Dhillon, Christina Volsko, Cynthia F. Bartels, Drew Adams, Ranjan Dutta, Michael D. Gallagher, William Phu, Alexey Kozlenkov, Stella Dracheva, Peter C. Scacheri, Paul J. Tesar, Olivia Corradin

    Published 2020
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