Resultats de la cerca - Downward, J

Epidermal growth factor regulates the exchange rate of guanine nucleotides on p21ras in fibroblasts. per Buday, L, Downward, J

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Antibodies to the autophosphorylation sites of the epidermal growth factor receptor protein-tyrosine kinase as probes of structure and function. per Gullick, W J, Downward, J, Waterfield, M D

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A Function for Phosphatidylinositol 3-Kinase β (p85α-p110β) in Fibroblasts during Mitogenesis: Requirement for Insulin- and Lysophosphatidic Acid-Mediated Signal Transduction per Roche, Serge, Downward, J., Raynal, Patrick, Courtneidge, Sara A.

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Proteolytic generation of constitutive tyrosine kinase activity of the human insulin receptor. per Hsuan, J J, Downward, J, Clark, S, Waterfield, M D

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Interaction of Ras with phosphoinositide 3-kinase gamma. per Rubio, I, Rodriguez-Viciana, P, Downward, J, Wetzker, R

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Stimulation of gene expression in neonatal rat ventricular myocytes by Ras is mediated by Ral guanine nucleotide dissociation stimulator (Ral.GDS) and phosphatidylinositol 3-kinase... per Fuller, S J, Finn, S G, Downward, J, Sugden, P H

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Identification of a nucleotide exchange-promoting activity for p21ras. per Downward, J, Riehl, R, Wu, L, Weinberg, R A

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p21ras-induced responsiveness of phosphatidylinositol turnover to bradykinin is a receptor number effect. per Downward, J, de Gunzburg, J, Riehl, R, Weinberg, R A

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Role of protein kinase C in T-cell antigen receptor regulation of p21ras: evidence that two p21ras regulatory pathways coexist in T cells. per Izquierdo, M, Downward, J, Graves, J D, Cantrell, D A

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Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway. per Khwaja, A, Rodriguez-Viciana, P, Wennström, S, Warne, P H, Downward, J

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Dominant negative inhibitors of signalling through the phosphoinositol 3-kinase pathway for gene therapy of pancreatic cancer per Stoll, V, Calleja, V, Vassaux, G, Downward, J, Lemoine, N R

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p21ras mediates control of IL-2 gene promoter function in T cell activation. per Rayter, S I, Woodrow, M, Lucas, S C, Cantrell, D A, Downward, J

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Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation. per Rodriguez-Viciana, P, Warne, P H, Vanhaesebroeck, B, Waterfield, M D, Downward, J

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Critical role for transcriptional repressor Snail2 in transformation by oncogenic RAS in colorectal carcinoma cells per Wang, Y, Ngo, VN, Marani, M, Yang, Y, Wright, G, Staudt, LM, Downward, J

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Transcriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cells. per Matsumura, I, Kitamura, T, Wakao, H, Tanaka, H, Hashimoto, K, Albanese, C, Downward, J, Pestell, R G, Kanakura, Y

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Evaluation of epidermal growth factor receptors in bladder tumours. per Berger, M. S., Greenfield, C., Gullick, W. J., Haley, J., Downward, J., Neal, D. E., Harris, A. L., Waterfield, M. D.

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Tyr-716 in the platelet-derived growth factor beta-receptor kinase insert is involved in GRB2 binding and Ras activation. per Arvidsson, A K, Rupp, E, Nånberg, E, Downward, J, Rönnstrand, L, Wennström, S, Schlessinger, J, Heldin, C H, Claesson-Welsh, L

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Involvement of Shc in insulin- and epidermal growth factor-induced activation of p21ras. per Pronk, G J, de Vries-Smits, A M, Buday, L, Downward, J, Maassen, J A, Medema, R H, Bos, J L

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Quantitation of class IA PI3Ks in mice reveals p110-free-p85s and isoform-selective subunit associations and recruitment to receptors per Tsolakos, N., Durrant, T. N., Chessa, T., Suire, S. M., Oxley, D., Kulkarni, S., Downward, J., Perisic, O., Williams, R. L., Stephens, L., Hawkins, P. T.

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Cage Environment Regulates Gut Microbiota Independent of Toll-Like Receptors per Lipinski, J. H., Zhou, X., Gurczynski, S. J., Erb-Downward, J. R., Dickson, R. P., Huffnagle, G. B., Moore, B. B., O’Dwyer, D. N.

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