Search Results - Doug Speed

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  1. 1
    MultiBLUP: improved SNP-based prediction for complex traits

    MultiBLUP: improved SNP-based prediction for complex traits by Doug Speed, David J. Balding

    Published 2014
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  2. 2
    SumHer better estimates the SNP heritability of complex traits from summary statistics

    SumHer better estimates the SNP heritability of complex traits from summary statistics by Doug Speed, David J. Balding

    Published 2018
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  3. 3
    Evaluating and improving heritability models using summary statistics

    Evaluating and improving heritability models using summary statistics by Doug Speed, John Bradley Holmes, David J. Balding

    Published 2020
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  4. 4
    Improved genetic prediction of complex traits from individual-level data or summary statistics

    Improved genetic prediction of complex traits from individual-level data or summary statistics by Qianqian Zhang, Florian Privé, Bjarni J. Vilhjálmsson, Doug Speed

    Published 2021
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  5. 5
    Improved Heritability Estimation from Genome-wide SNPs

    Improved Heritability Estimation from Genome-wide SNPs by Doug Speed, Gibran Hemani, Michael R. Johnson, David J. Balding

    Published 2012
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  6. 6
    Reevaluation of SNP heritability in complex human traits

    Reevaluation of SNP heritability in complex human traits by Doug Speed, Na Cai, Michael R. Johnson, Sergey Nejentsev, David J. Balding

    Published 2017
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  7. 7
    Investigating the association between body fat and depression via Mendelian randomization

    Investigating the association between body fat and depression via Mendelian randomization by Maria Speed, Oskar Hougaard Jefsen, Anders D. Børglum, Doug Speed, Søren Dinesen Østergaard

    Published 2019
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  8. 8
    Participation bias in the UK Biobank distorts genetic associations and downstream analyses

    Participation bias in the UK Biobank distorts genetic associations and downstream analyses by Tabea Schoeler, Doug Speed, Eleonora Porcu, Nicola Pirastu, Jean‐Baptiste Pingault, Zoltán Kutalik

    Published 2023
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  9. 9
    Describing the genetic architecture of epilepsy through heritability analysis

    Describing the genetic architecture of epilepsy through heritability analysis by Doug Speed, Terence J. O’Brien, Aarno Palotie, Kirill Shkura, Anthony G Marson, David J. Balding, Michael R. Johnson

    Published 2014
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  10. 10
    Transient structural variations have strong effects on quantitative traits and reproductive isolation in fission yeast

    Transient structural variations have strong effects on quantitative traits and reproductive isolation in fission yeast by Daniel Jeffares, Clemency Jolly, Mimoza Hoti, Doug Speed, Liam P. Shaw, Charalampos Rallis, François Balloux, Christophe Dessimoz, Jürg Bähler, Fritz J. Sedlazeck

    Published 2017
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  11. 11
    Genetic Complexity of Crohn’s Disease in Two Large Ashkenazi Jewish Families

    Genetic Complexity of Crohn’s Disease in Two Large Ashkenazi Jewish Families by Adam P. Levine, Nikolas Pontikos, Elena Schiff, Luke Jostins, Doug Speed, Laurence Lovat, Jeffrey C. Barrett, Helmut Grasberger, Vincent Plagnol, Anthony W. Segal

    Published 2016
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  12. 12
    Mendelian randomization study shows no causal relationship between circulating urate levels and Parkinson's disease

    Mendelian randomization study shows no causal relationship between circulating urate levels and Parkinson's disease by Demis A. Kia, Alastair Noyce, Jon White, Doug Speed, Aude Nicolas, Stephen Burgess, Debbie A. Lawlor, George Davey Smith, Andrew Singleton, Mike A. Nalls, Reecha Sofat, Nicholas Wood

    Published 2018
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  13. 13
    Heritability and polygenic load for comorbid anxiety and depression

    Heritability and polygenic load for comorbid anxiety and depression by Fara Tabrizi, Jörgen Rosén, Hampus Grönvall, Victor Rahimzadeh William-Olsson, Peter Arner, Patrik K. E. Magnusson, Camilla Palm, Henrik Larsson, Alexander Viktorin, Jens Bernhardsson, Johanna Björkdahl, Billy Jansson, Örjan Sundin, Xuan Zhou, Doug Speed, Fredrik Åhs

    Published 2025
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  14. 14
    Graph pangenome captures missing heritability and empowers tomato breeding

    Graph pangenome captures missing heritability and empowers tomato breeding by Yao Zhou, Zhiyang Zhang, Zhigui Bao, Hongbo Li, Yaqing Lyu, Yanjun Zan, Yaoyao Wu, Lin Cheng, Yuhan Fang, Kun Wu, Jinzhe Zhang, Hongjun Lyu, Tao Lin, Qiang Gao, Surya Saha, Lukas A. Mueller, Zhangjun Fei, Thomas Städler, Shizhong Xu, Zhiwu Zhang, Doug Speed, Sanwen Huang

    Published 2022
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  15. 15
    Parasite genotype is a major predictor of mortality from visceral leishmaniasis

    Parasite genotype is a major predictor of mortality from visceral leishmaniasis by Cooper Alastair Grace, Kátia Silene Sousa Carvalho, Mayara Ingrid Sousa Lima, Vladimir Costa Silva, João Luís Reis-Cunha, Matthew J. Brune, Sarah Forrester, Conceição de Maria Pedrozo e Silva de Azevedo, Dorcas Lamounier Costa, Doug Speed, Jeremy C. Mottram, Daniel Jeffares, Carlos Henrique Nery Costa

    Published 2022
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  16. 16
    Parasite Genotype Is a Major Predictor of Mortality from Visceral Leishmaniasis

    Parasite Genotype Is a Major Predictor of Mortality from Visceral Leishmaniasis by Cooper Alastair Grace, Kátia Silene Sousa Carvalho, Mayara Ingrid Sousa Lima, Vladimir Costa Silva, João Luís Reis-Cunha, Matthew J. Brune, Sarah Forrester, Conceição de Maria Pedrozo e Silva de Azevedo, Dorcas Lamounier Costa, Doug Speed, Jeremy C. Mottram, Daniel Jeffares, Carlos Henrique Nery Costa

    Published 2022
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  17. 17
    Genetic correlations among psychiatric and immune‐related phenotypes based on genome‐wide association data

    Genetic correlations among psychiatric and immune‐related phenotypes based on genome‐wide association data by Daniel S. Tylee, Jiayin Sun, Jonathan Hess, Muhammad A. Tahir, Esha Sharma, Rainer Malik, Bradford B. Worrall, Andrew J. Levine, Jeremy Martinson, Sergey Nejentsev, Doug Speed, Annegret Fischer, Eric Mick, Brian R. Walker, Andrew Crawford, Struan F.A. Grant, Constantin Polychronakos, Jonathan P. Bradfield, Patrick Sleiman, Hákon Hákonarson, Eva Ellinghaus, James T. Elder, Lam C. Tsoi, Richard C. Trembath, Juliet N. Barker, André Franke, Abbas Dehghan, Stephen V. Faraone, Stephen J. Glatt

    Published 2018
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  18. 18
    The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

    The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups by Christina Curtis, Sohrab P. Shah, Suet‐Feung Chin, Gulisa Turashvili, Oscar M. Rueda, Mark Dunning, Doug Speed, Andy G. Lynch, Shamith A. Samarajiwa, Yinyin Yuan, Stefan Gräf, Gavin Ha, Gholamreza Haffari, Ali Bashashati, Roslin Russell, Steven McKinney, Anita Langerød, Andrew R. Green, Elena Provenzano, Gordon Wishart, Sarah E. Pinder, Peter H. Watson, Florian Markowetz, Leigh C. Murphy, Ian O. Ellis, Arnie Purushotham, Anne‐Lise Børresen‐Dale, James D. Brenton, Simon Tavaré, Carlos Caldas, Samuel Aparício

    Published 2012
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  19. 19
    Genome-wide association meta-analyses of drug-resistant epilepsy

    Genome-wide association meta-analyses of drug-resistant epilepsy by Costin Leu, Andreja Avberšek, Remi Stevelink, Helena Martins Custodio, Siwei Chen, Doug Speed, Caitlin A. Bennett, Lina Jönsson, Unnur Unnsteinsdóttir, Andrea Jorgensen, Gianpiero L. Cavalleri, Norman Delanty, John Craig, Chantal Depondt, Michael R. Johnson, Bobby P.C. Koeleman, Emadeldin Hassanin, Maryam Omidvar, Roland Krause, Holger Lerche, Anthony G Marson, Terence J. O’Brien, Josemir W. Sander, Graeme J. Sills, Pasquale Striano, Federico Zara, Hreinn Stefánsson, Hreinn Stefánsson, Patrick May, Benjamin M. Neale, Dennis Lal, Samuel F. Berkovic, Sanjay M. Sisodiya

    Published 2025
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  20. 20
    Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus

    Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus by Michael R. Johnson, Jacques Behmoaras, Leonardo Bottolo, Michelle L. Krishnan, Katharina Pernhorst, Paola L. Meza Santoscoy, Tiziana Rossetti, Doug Speed, Prashant K. Srivastava, Marc Chadeau‐Hyam, Nabil Hajji, Aleksandra Dąbrowska, Maxime Rotival, Banafsheh Razzaghi, Stjepana Kovac, Klaus Wanisch, Federico W. Grillo, Anna Slaviero, Sarah R. Langley, Kirill Shkura, Paolo Roncon, Tisham De, Manuel Mattheisen, Pitt Niehusmann, Terence J. O’Brien, Slavé Petrovski, Marec von Lehe, Per Hoffmann, Johan G. Eriksson, Alison J. Coffey, Sven Cichon, Matthew C. Walker, Michele Simonato, Bénédicte Danis, Manuela Mazzuferi, Patrik Foerch, Susanne Schoch, Vincenzo De Paola, Rafał M. Kamiński, Vincent T. Cunliffe, Albert J. Becker, Enrico Petretto

    Published 2015
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