Canlyniadau Chwilio - Doerflinger, Marcel

BH3-only proteins: the thorny end of the ER stress response gan Glab, Jason A, Doerflinger, Marcel, Puthalakath, Hamsa

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Mycobacterium tuberculosis: Rewiring host cell signaling to promote infection gan Stutz, Michael D., Clark, Michelle P., Doerflinger, Marcel, Pellegrini, Marc

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Programmed cell death: the pathways to severe COVID-19? gan Bader, Stefanie M., Cooney, James P., Pellegrini, Marc, Doerflinger, Marcel

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Caspase-2 does not play a critical role in cell death induction and bacterial clearance during Salmonella infection gan Engel, Sven, Doerflinger, Marcel, Lee, Ariane R., Strasser, Andreas, Herold, Marco J., Bedoui, Sammy, Bachem, Annabell

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The role of MKK4 in T‐cell development and immunity to viral infections gan Preston, Simon P, Doerflinger, Marcel, Scott, Hamish W, Allison, Cody C, Horton, Miles, Cooney, James, Pellegrini, Marc

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Chemical chaperone TUDCA prevents apoptosis and improves survival during polymicrobial sepsis in mice gan Doerflinger, Marcel, Glab, Jason, Nedeva, Christina, Jose, Irvin, Lin, Ann, O’Reilly, Lorraine, Allison, Cody, Pellegrini, Marc, Hotchkiss, Richard S., Puthalakath, Hamsa

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Successful identification of predictive profiles for infection utilising systems‐level immune analysis: a pilot study in patients with relapsed and refractory multiple myeloma gan Doerflinger, Marcel, Garnham, Alexandra L, Freytag, Saskia, Harrison, Simon J, Prince, H Miles, Quach, Hang, Slavin, Monica A, Pellegrini, Marc, Teh, Benjamin W

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DR5 and caspase-8 are dispensable in ER stress-induced apoptosis gan Glab, Jason A, Doerflinger, Marcel, Nedeva, Christina, Jose, Irvin, Mbogo, George W, Paton, James C, Paton, Adrienne W, Kueh, Andrew J, Herold, Marco J, Huang, David CS, Segal, David, Brumatti, Gabriella, Puthalakath, Hamsa

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Procalcitonin and Interleukin-10 May Assist in Early Prediction of Bacteraemia in Children With Cancer and Febrile Neutropenia gan Doerflinger, Marcel, Haeusler, Gabrielle M., Li-Wai-Suen, Connie S. N., Clark, Julia E., Slavin, Monica, Babl, Franz E., Allaway, Zoe, Mechinaud, Francoise, Smyth, Gordon K., De Abreu Lourenco, Richard, Phillips, Bob, Pellegrini, Marc, Thursky, Karin A.

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Blood transcriptomics identifies immune signatures indicative of infectious complications in childhood cancer patients with febrile neutropenia gan Haeusler, Gabrielle M, Garnham, Alexandra L, Li‐Wai‐Suen, Connie SN, Clark, Julia E, Babl, Franz E, Allaway, Zoe, Slavin, Monica A, Mechinaud, Francoise, Smyth, Gordon K, Phillips, Bob, Thursky, Karin A, Pellegrini, Marc, Doerflinger, Marcel

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Tankyrase-mediated ADP-ribosylation is a regulator of TNF-induced death gan Liu, Lin, Sandow, Jarrod J., Leslie Pedrioli, Deena M., Samson, Andre L., Silke, Natasha, Kratina, Tobias, Ambrose, Rebecca L., Doerflinger, Marcel, Hu, Zhaoqing, Morrish, Emma, Chau, Diep, Kueh, Andrew J., Fitzibbon, Cheree, Pellegrini, Marc, Pearson, Jaclyn S., Hottiger, Michael O., Webb, Andrew I., Lalaoui, Najoua, Silke, John

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BCL-2 family protein BOK is a positive regulator of uridine metabolism in mammals gan Srivastava, Rahul, Cao, Zhipeng, Nedeva, Christina, Naim, Samara, Bachmann, Daniel, Rabachini, Tatiana, Gangoda, Lahiru, Shahi, Sanjay, Glab, Jason, Menassa, Joseph, Osellame, Laura, Nelson, Tao, Fernandez-Marrero, Yuniel, Brown, Fiona, Wei, Andrew, Ke, Francine, O’Reilly, Lorraine, Doerflinger, Marcel, Allison, Cody, Kueh, Andrew, Ramsay, Rob, Smith, Brian J., Mathivanan, Suresh, Kaufmann, Thomas, Puthalakath, Hamsa

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i-bodies, Human Single Domain Antibodies That Antagonize Chemokine Receptor CXCR4 gan Griffiths, Katherine, Dolezal, Olan, Cao, Benjamin, Nilsson, Susan K., See, Heng B., Pfleger, Kevin D. G., Roche, Michael, Gorry, Paul R., Pow, Andrew, Viduka, Katerina, Lim, Kevin, Lu, Bernadine G. C., Chang, Denison H. C., Murray-Rust, Thomas, Kvansakul, Marc, Perugini, Matthew A., Dogovski, Con, Doerflinger, Marcel, Zhang, Yuan, Parisi, Kathy, Casey, Joanne L., Nuttall, Stewart D., Foley, Michael

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Ubiquitylation of RIPK3 beyond-the-RHIM can limit RIPK3 activity and cell death gan Frank, Daniel, Garnish, Sarah E., Sandow, Jarrod J., Weir, Ashley, Liu, Lin, Clayer, Elise, Meza, Lizeth, Rashidi, Maryam, Cobbold, Simon A., Scutts, Simon R., Doerflinger, Marcel, Anderton, Holly, Lawlor, Kate E., Lalaoui, Najoua, Kueh, Andrew J., Eng, Vik Ven, Ambrose, Rebecca L., Herold, Marco J., Samson, Andre L., Feltham, Rebecca, Murphy, James M., Ebert, Gregor, Pearson, Jaclyn S., Vince, James E.

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Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection gan Doerflinger, Marcel, Deng, Yexuan, Whitney, Paul, Salvamoser, Ranja, Engel, Sven, Kueh, Andrew J., Tai, Lin, Bachem, Annabell, Gressier, Elise, Geoghegan, Niall D., Wilcox, Stephen, Rogers, Kelly L., Garnham, Alexandra L., Dengler, Michael A., Bader, Stefanie M., Ebert, Gregor, Pearson, Jaclyn S., De Nardo, Dominic, Wang, Nancy, Yang, Chenying, Pereira, Milton, Bryant, Clare E., Strugnell, Richard A., Vince, James E., Pellegrini, Marc, Strasser, Andreas, Bedoui, Sammy, Herold, Marco J.

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Insights Into Drug Repurposing, as Well as Specificity and Compound Properties of Piperidine-Based SARS-CoV-2 PLpro Inhibitors gan Calleja, Dale J., Kuchel, Nathan, Lu, Bernadine G. C., Birkinshaw, Richard W., Klemm, Theresa, Doerflinger, Marcel, Cooney, James P., Mackiewicz, Liana, Au, Amanda E., Yap, Yu Q., Blackmore, Timothy R, Katneni, Kasiram, Crighton, Elly, Newman, Janet, Jarman, Kate E., Call, Melissa J., Lechtenberg, Bernhard C., Czabotar, Peter E., Pellegrini, Marc, Charman, Susan A., Lowes, Kym N., Mitchell, Jeffrey P., Nachbur, Ueli, Lessene, Guillaume, Komander, David

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Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2 gan Klemm, Theresa, Ebert, Gregor, Calleja, Dale J, Allison, Cody C, Richardson, Lachlan W, Bernardini, Jonathan P, Lu, Bernadine GC, Kuchel, Nathan W, Grohmann, Christoph, Shibata, Yuri, Gan, Zhong Yan, Cooney, James P, Doerflinger, Marcel, Au, Amanda E, Blackmore, Timothy R, van der Heden van Noort, Gerbrand J, Geurink, Paul P, Ovaa, Huib, Newman, Janet, Riboldi‐Tunnicliffe, Alan, Czabotar, Peter E, Mitchell, Jeffrey P, Feltham, Rebecca, Lechtenberg, Bernhard C, Lowes, Kym N, Dewson, Grant, Pellegrini, Marc, Lessene, Guillaume, Komander, David

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Nanobody cocktails potently neutralize SARS-CoV-2 D614G N501Y variant and protect mice gan Pymm, Phillip, Adair, Amy, Chan, Li-Jin, Cooney, James P., Mordant, Francesca L., Allison, Cody C., Lopez, Ester, Haycroft, Ebene R., O’Neill, Matthew T., Tan, Li Lynn, Dietrich, Melanie H., Drew, Damien, Doerflinger, Marcel, Dengler, Michael A., Scott, Nichollas E., Wheatley, Adam K., Gherardin, Nicholas A., Venugopal, Hariprasad, Cromer, Deborah, Davenport, Miles P., Pickering, Raelene, Godfrey, Dale I., Purcell, Damian F. J., Kent, Stephen J., Chung, Amy W., Subbarao, Kanta, Pellegrini, Marc, Glukhova, Alisa, Tham, Wai-Hong

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Interferon-γ primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway gan Simpson, Daniel S., Pang, Jiyi, Weir, Ashley, Kong, Isabella Y., Fritsch, Melanie, Rashidi, Maryam, Cooney, James P., Davidson, Kathryn C., Speir, Mary, Djajawi, Tirta M., Hughes, Sebastian, Mackiewicz, Liana, Dayton, Merle, Anderton, Holly, Doerflinger, Marcel, Deng, Yexuan, Huang, Allan Shuai, Conos, Stephanie A., Tye, Hazel, Chow, Seong H., Rahman, Arfatur, Norton, Raymond S., Naderer, Thomas, Nicholson, Sandra E., Burgio, Gaetan, Man, Si Ming, Groom, Joanna R., Herold, Marco J., Hawkins, Edwin D., Lawlor, Kate E., Strasser, Andreas, Silke, John, Pellegrini, Marc, Kashkar, Hamid, Feltham, Rebecca, Vince, James E.

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