תוצאות חיפוש - Dirk Wienke

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  1. 1
    Endosomes generate localized Rho–ROCK–MLC2–based contractile signals via Endo180 to promote adhesion disassembly

    Endosomes generate localized Rho–ROCK–MLC2–based contractile signals via Endo180 to promote adhesion disassembly מאת Justin Sturge, Dirk Wienke, Clare M. Isacke

    יצא לאור 2006
    קבל טקסט מלא
    Artigo
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  2. 2
    Identification and Characterization of the Endocytic Transmembrane Glycoprotein Endo180 as a Novel Collagen Receptor

    Identification and Characterization of the Endocytic Transmembrane Glycoprotein Endo180 as a Novel Collagen Receptor מאת Dirk Wienke, John MacFadyen, Clare M. Isacke

    יצא לאור 2003
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    Artigo
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  3. 3
    A targeted deletion in the endocytic receptor gene <i>Endo180</i> results in a defect in collagen uptake

    A targeted deletion in the endocytic receptor gene <i>Endo180</i> results in a defect in collagen uptake מאת Lucy East, Afshan McCarthy, Dirk Wienke, Justin Sturge, Alan Ashworth, Clare M. Isacke

    יצא לאור 2003
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    Artigo
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  4. 4
    Disruption of a Dynamin Homologue Affects Endocytosis, Organelle Morphology, and Cytokinesis in<i>Dictyostelium discoideum</i>

    Disruption of a Dynamin Homologue Affects Endocytosis, Organelle Morphology, and Cytokinesis in<i>Dictyostelium discoideum</i> מאת Dirk Wienke, Menno L. W. Knetsch, Eva M. Neuhaus, Mary C. Reedy, Dietmar J. Manstein

    יצא לאור 1999
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    Artigo
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  5. 5
    Structural Model for the Mannose Receptor Family Uncovered by Electron Microscopy of Endo180 and the Mannose Receptor

    Structural Model for the Mannose Receptor Family Uncovered by Electron Microscopy of Endo180 and the Mannose Receptor מאת Jasminka Boskovic, James N. Arnold, Richard Stilion, Siamon Gordon, Robert B. Sim, Ángel Rivera-Calzada, Dirk Wienke, Clare M. Isacke, Luisa Martı́nez-Pomares, Óscar Llorca

    יצא לאור 2006
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    Artigo
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  6. 6
    Carbohydrate-independent recognition of collagens by the macrophage mannose receptor

    Carbohydrate-independent recognition of collagens by the macrophage mannose receptor מאת Luisa Martı́nez-Pomares, Dirk Wienke, Richard Stillion, Emma McKenzie, James N. Arnold, James Harris, Eamon P. McGreal, Robert B. Sim, Clare M. Isacke, Siamon Gordon

    יצא לאור 2006
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    Artigo
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  7. 7
    The Collagen Receptor Endo180 (CD280) Is Expressed on Basal-like Breast Tumor Cells and Promotes Tumor Growth <i>In vivo</i>

    The Collagen Receptor Endo180 (CD280) Is Expressed on Basal-like Breast Tumor Cells and Promotes Tumor Growth <i>In vivo</i> מאת Dirk Wienke, Gareth Davies, Damian A. Johnson, Justin Sturge, Maryou B. Lambros, Kay Savage, Somaia Elsheikh, Andrew R. Green, Ian O. Ellis, David Robertson, Jorge S. Reis‐Filho, Clare M. Isacke

    יצא לאור 2007
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    Artigo
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  8. 8
    Endosialin (TEM1, CD248) is a marker of stromal fibroblasts and is not selectively expressed on tumour endothelium

    Endosialin (TEM1, CD248) is a marker of stromal fibroblasts and is not selectively expressed on tumour endothelium מאת John MacFadyen, Oliver Haworth, David Roberston, Deborah Hardie, Marie-Thérèse Webster, Howard R. Morris, Maria Panico, Mark Sutton‐Smith, Anne Dell, Peter van der Geer, Dirk Wienke, Christopher D. Buckley, Clare M. Isacke

    יצא לאור 2005
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    Artigo
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  9. 9
    Structure-Based Optimization of Potent, Selective, and Orally Bioavailable CDK8 Inhibitors Discovered by High-Throughput Screening

    Structure-Based Optimization of Potent, Selective, and Orally Bioavailable CDK8 Inhibitors Discovered by High-Throughput Screening מאת Paul Czodrowski, Aurélie Mallinger, Dirk Wienke, Christina Esdar, Oliver Pöschke, Michael Busch, Felix Rohdich, Suzanne A. Eccles, Maria-Jesus Ortiz-Ruiz, Richard Schneider, Florence I. Raynaud, Paul A. Clarke, Djordje Müsil, Dániel Schwarz, Trevor Dale, Klaus Urbahns, Julian Blagg, Kai Schiemann

    יצא לאור 2016
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    Artigo
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  10. 10
    A novel tankyrase inhibitor, MSC2504877, enhances the effects of clinical CDK4/6 inhibitors

    A novel tankyrase inhibitor, MSC2504877, enhances the effects of clinical CDK4/6 inhibitors מאת Malini Menon, Richard Elliott, Leandra Bowers, Nicolae Balan, Rumana Rafiq, Sara Costa-Cabral, Felix M. Munkonge, Ines Trinidade, Roderick A. Porter, Andrew D. Campbell, Emma Johnson, Christina Esdar, Hans‐Peter Buchstaller, Birgitta Leuthner, Felix Rohdich, Richard Schneider, Owen J. Sansom, Dirk Wienke, Alan Ashworth, Christopher J. Lord

    יצא לאור 2019
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    Artigo
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  11. 11
    2,8-Disubstituted-1,6-Naphthyridines and 4,6-Disubstituted-Isoquinolines with Potent, Selective Affinity for CDK8/19

    2,8-Disubstituted-1,6-Naphthyridines and 4,6-Disubstituted-Isoquinolines with Potent, Selective Affinity for CDK8/19 מאת Aurélie Mallinger, Kai Schiemann, Christian Rink, Jimmy J. P. Sejberg, Mark A. Honey, Paul Czodrowski, Mark Stubbs, Oliver Poeschke, Michael Busch, Richard Schneider, Dániel Schwarz, Djordje Müsil, Rosemary Burke, Klaus Urbahns, Paul Workman, Dirk Wienke, Paul A. Clarke, Florence I. Raynaud, Suzanne A. Eccles, Christina Esdar, Felix Rohdich, Julian Blagg

    יצא לאור 2016
    קבל טקסט מלא
    Artigo
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  12. 12
    Discovery of Potent, Selective, and Orally Bioavailable Small-Molecule Modulators of the Mediator Complex-Associated Kinases CDK8 and CDK19

    Discovery of Potent, Selective, and Orally Bioavailable Small-Molecule Modulators of the Mediator Complex-Associated Kinases CDK8 and CDK19 מאת Aurélie Mallinger, Kai Schiemann, Christian Rink, Frank Stieber, Michel Calderini, Simon Crumpler, Mark Stubbs, Olajumoke Adeniji-Popoola, Oliver Poeschke, Michael Busch, Paul Czodrowski, Djordje Müsil, Dániel Schwarz, Maria-Jesus Ortiz-Ruiz, Richard Schneider, Ching Thai, Melanie Valenti, Alexis de Haven Brandon, Rosemary Burke, Paul Workman, Trevor Dale, Dirk Wienke, Paul A. Clarke, Christina Esdar, Florence I. Raynaud, Suzanne A. Eccles, Felix Rohdich, Julian Blagg

    יצא לאור 2016
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    Artigo
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  13. 13
    A selective chemical probe for exploring the role of CDK8 and CDK19 in human disease

    A selective chemical probe for exploring the role of CDK8 and CDK19 in human disease מאת Trevor Dale, Paul A. Clarke, Christina Esdar, Dennis Waalboer, Olajumoke Adeniji-Popoola, Maria-Jesus Ortiz-Ruiz, Aurélie Mallinger, Rahul S. Samant, Paul Czodrowski, Djordje Müsil, Dániel Schwarz, Klaus Schneider, Mark Stubbs, Kenneth Ewan, Elizabeth Fraser, Robert te Poele, Will Court, Gary Box, Melanie Valenti, Alexis de Haven Brandon, Sharon Gowan, Felix Rohdich, Florence I. Raynaud, Richard Schneider, Oliver Poeschke, Andree Blaukat, Paul Workman, Kai Schiemann, Suzanne A. Eccles, Dirk Wienke, Julian Blagg

    יצא לאור 2015
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    Artigo
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  14. 14
    Discovery of Potent, Orally Bioavailable, Small-Molecule Inhibitors of WNT Signaling from a Cell-Based Pathway Screen

    Discovery of Potent, Orally Bioavailable, Small-Molecule Inhibitors of WNT Signaling from a Cell-Based Pathway Screen מאת Aurélie Mallinger, Simon Crumpler, Mark Pichowicz, Dennis Waalboer, Mark Stubbs, Olajumoke Adeniji-Popoola, Bozena Wood, Elizabeth Smith, Ching Thai, Alan T. Henley, Katrin Georgi, William Court, Steve Hobbs, Gary Box, Maria-Jesus Ortiz-Ruiz, Melanie Valenti, Alexis de Haven Brandon, Robert te Poele, Birgitta Leuthner, Paul Workman, Wynne Aherne, Oliver Poeschke, Trevor Dale, Dirk Wienke, Christina Esdar, Felix Rohdich, Florence I. Raynaud, Paul A. Clarke, Suzanne A. Eccles, Frank Stieber, Kai Schiemann, Julian Blagg

    יצא לאור 2015
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    Artigo
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  15. 15
    Assessing the mechanism and therapeutic potential of modulators of the human Mediator complex-associated protein kinases

    Assessing the mechanism and therapeutic potential of modulators of the human Mediator complex-associated protein kinases מאת Paul A. Clarke, Maria-Jesus Ortiz-Ruiz, Robert te Poele, Olajumoke Adeniji-Popoola, Gary Box, Will Court, Stephanie Czasch, Samer El Bawab, Christina Esdar, Kenneth Ewan, Sharon Gowan, Alexis de Haven Brandon, Phillip Hewitt, Stephen M. Hobbs, Wolfgang Kaufmann, Aurélie Mallinger, Florence I. Raynaud, Toby Roe, Felix Rohdich, Kai Schiemann, Stéphanie Simon, Richard Schneider, Melanie Valenti, Stefan Weigt, Julian Blagg, Andree Blaukat, Trevor Dale, Suzanne A. Eccles, Stefan Hecht, Klaus Urbahns, Paul Workman, Dirk Wienke

    יצא לאור 2016
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    Artigo
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  16. 16
    Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors

    Molecular dissection of colorectal cancer in pre-clinical models identifies biomarkers predicting sensitivity to EGFR inhibitors מאת Moritz Schütte, Thomas S. Risch, Nilofar Abdavi-Azar, Karsten Boehnke, Dirk Schumacher, Marlen Keil, Reha Yildiriman, Christine Jandrasits, Tatiana Borodina, Vyacheslav Amstislavskiy, Catherine L. Worth, Caroline Schweiger, Sandra Liebs, Martin Lange, Hans- Jörg Warnatz, Lee M Butcher, James E. Barrett, Marc Sultan, Christoph Wierling, Nicole Golob‐Schwarzl, Sigurd Lax, Stefan Uranitsch, Michael W. Becker, Yvonne Welte, Joseph L. Regan, Maxine Silvestrov, Inge Kehler, Alberto Fusi, T. Keßler, Ralf Herwig, Ulf Landegren, Dirk Wienke, Mats Nilsson, Juan A. Velasco, Pilar Garin‐Chesa, Christoph Reinhard, Stephan Beck, Reinhold Schäfer, Christian Regenbrecht, David Henderson, Bodo Lange, Johannes Haybaeck, Ulrich Keilholz, Jens Hoffmann, Hans Lehrach, Marie‐Laure Yaspo

    יצא לאור 2017
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    Artigo
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