Search Results - Dimitri Y. Chirgadze

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  1. 1
    Crystal structure of DNA-PKcs reveals a large open-ring cradle comprised of HEAT repeats

    Crystal structure of DNA-PKcs reveals a large open-ring cradle comprised of HEAT repeats by B. L. Sibanda, Dimitri Y. Chirgadze, Tom L. Blundell

    Published 2009
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  2. 2
    Crystal structures of NK1-heparin complexes reveal the basis for NK1 activity and enable engineering of potent agonists of the MET receptor

    Crystal structures of NK1-heparin complexes reveal the basis for NK1 activity and enable engineering of potent agonists of the MET receptor by Daniel Lietha, Dimitri Y. Chirgadze, Barbara Mulloy, Tom L. Blundell, Ermanno Gherardi

    Published 2001
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  3. 3
    DNA-PKcs structure suggests an allosteric mechanism modulating DNA double-strand break repair

    DNA-PKcs structure suggests an allosteric mechanism modulating DNA double-strand break repair by B. L. Sibanda, Dimitri Y. Chirgadze, David B. Ascher, Tom L. Blundell

    Published 2017
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  4. 4
    CryoEM structures of human CMG–ATPγS–DNA and CMG–AND-1 complexes

    CryoEM structures of human CMG–ATPγS–DNA and CMG–AND-1 complexes by Neil J. Rzechorzek, Steven W. Hardwick, Vincentius A Jatikusumo, Dimitri Y. Chirgadze, Luca Pellegrini

    Published 2020
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  5. 5
    A new look at sodium channel β subunits

    A new look at sodium channel β subunits by Sivakumar Namadurai, Nikitha R. Yereddi, Fiona S. Cusdin, Christopher Huang, Dimitri Y. Chirgadze, Antony P. Jackson

    Published 2015
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  6. 6
    5-Formylcytosine alters the structure of the DNA double helix

    5-Formylcytosine alters the structure of the DNA double helix by Eun‐Ang Raiber, Pierre Murat, Dimitri Y. Chirgadze, Dario Beraldi, Ben F. Luisi, Shankar Balasubramanian

    Published 2014
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  7. 7
    Structural insights into inhibitor regulation of the DNA repair protein DNA-PKcs

    Structural insights into inhibitor regulation of the DNA repair protein DNA-PKcs by Shikang Liang, S.E. Thomas, Amanda K. Chaplin, Steven W. Hardwick, Dimitri Y. Chirgadze, Tom L. Blundell

    Published 2022
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  8. 8
    Crystal Structure and Molecular Imaging of the Nav Channel β3 Subunit Indicates a Trimeric Assembly

    Crystal Structure and Molecular Imaging of the Nav Channel β3 Subunit Indicates a Trimeric Assembly by Sivakumar Namadurai, Dilshan Balasuriya, Rajit Rajappa, Martin Wiemhöfer, Katherine Stott, Jürgen Klingauf, J. Michael Edwardson, Dimitri Y. Chirgadze, Antony P. Jackson

    Published 2014
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  9. 9
    Mechanisms of inhibition and activation of extrasynaptic αβ GABAA receptors

    Mechanisms of inhibition and activation of extrasynaptic αβ GABAA receptors by Vikram Babu Kasaragod, Martin Mortensen, Steven W. Hardwick, Ayla A. Wahid, Valentina Dorovykh, Dimitri Y. Chirgadze, Trevor G. Smart, Paul S. Miller

    Published 2022
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  10. 10
    Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ

    Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ by Yi Li, Dimitri Y. Chirgadze, Víctor M. Bolaños-García, B. L. Sibanda, Owen R. Davies, Peter Ahnesorg, Stephen P. Jackson, Tom L. Blundell

    Published 2007
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  11. 11
    The Influence of Pathogenic Mutations in α-Synuclein on Biophysical and Structural Characteristics of Amyloid Fibrils

    The Influence of Pathogenic Mutations in α-Synuclein on Biophysical and Structural Characteristics of Amyloid Fibrils by Francesco Simone Ruggeri, Patrick Flagmeier, Janet R. Kumita, Georg Meisl, Dimitri Y. Chirgadze, Marie N. Bongiovanni, Tuomas P. J. Knowles, Christopher M. Dobson

    Published 2020
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  12. 12
    Structural basis for human mitochondrial tRNA maturation

    Structural basis for human mitochondrial tRNA maturation by Vincent Meynier, Steven W. Hardwick, Marjorie Catala, Johann J Roske, Stephanie Oerum, Dimitri Y. Chirgadze, Pierre Barraud, Wyatt W. Yue, Ben F. Luisi, Carine Tisné

    Published 2024
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  13. 13
    Dimers of DNA-PK create a stage for DNA double-strand break repair

    Dimers of DNA-PK create a stage for DNA double-strand break repair by Amanda K. Chaplin, Steven W. Hardwick, Shikang Liang, Antonia Kefala Stavridi, Aleš Hnı́zda, Lee R. Cooper, Taianá Maia de Oliveira, Dimitri Y. Chirgadze, Tom L. Blundell

    Published 2020
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  14. 14
    Crystal structure of folliculin reveals a hidDENN function in genetically inherited renal cancer

    Crystal structure of folliculin reveals a hidDENN function in genetically inherited renal cancer by Ravi K. Nookala, Lars Langemeyer, A. Pacitto, Bernardo Ochoa‐Montaño, Jane C. Donaldson, Beata K. Blaszczyk, Dimitri Y. Chirgadze, Francis A. Barr, J. Fernando Bazán, Tom L. Blundell

    Published 2012
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  15. 15
    Structure of a Blinkin-BUBR1 Complex Reveals an Interaction Crucial for Kinetochore-Mitotic Checkpoint Regulation via an Unanticipated Binding Site

    Structure of a Blinkin-BUBR1 Complex Reveals an Interaction Crucial for Kinetochore-Mitotic Checkpoint Regulation via an Unanticipated Binding Site by Víctor M. Bolaños-García, Tiziana Lischetti, Dijana Matak‐Vinković, Ernesto Cota, P. J. Simpson, Dimitri Y. Chirgadze, David R. Spring, Carol V. Robinson, Jakob Nilsson, Tom L. Blundell

    Published 2011
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  16. 16
    Structural basis for collagen recognition by the immune receptor OSCAR

    Structural basis for collagen recognition by the immune receptor OSCAR by Long Zhou, Jennifer M. Hinerman, M. Blasz̧czyk, Jeanette L. C. Miller, Deborah G. Conrady, Alexander D. Barrow, Dimitri Y. Chirgadze, Dominique Bihan, Richard W. Farndale, Andrew B. Herr

    Published 2015
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  17. 17
    Differential assembly diversifies GABAA receptor structures and signalling

    Differential assembly diversifies GABAA receptor structures and signalling by Andrija Sente, Rooma Desai, Katerina Naydenova, Tomas Malinauskas, Youssef Jounaïdi, Jonas Miehling, Xiaojuan Zhou, Simonas Masiulis, Steven W. Hardwick, Dimitri Y. Chirgadze, Keith W. Miller, A.R. Aricescu

    Published 2022
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  18. 18
    The structure of EXTL3 helps to explain the different roles of bi-domain exostosins in heparan sulfate synthesis

    The structure of EXTL3 helps to explain the different roles of bi-domain exostosins in heparan sulfate synthesis by Louis F. L. Wilson, Tom Dendooven, Steven W. Hardwick, Alberto Echevarría‐Poza, Theodora Tryfona, Kristian B. R. M. Krogh, Dimitri Y. Chirgadze, Ben F. Luisi, Derek T. Logan, Katrin Mani, Paul Dupree

    Published 2022
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  19. 19
    Structural and functional insights into the interaction between Ku70/80 and Pol X family polymerases in NHEJ

    Structural and functional insights into the interaction between Ku70/80 and Pol X family polymerases in NHEJ by Philippe Frit, Himani Amin, Sayma Zahid, Nadia Barboule, Chloe M. Hall, Gurdip Matharu, Steven W. Hardwick, Jeanne Chauvat, Sébastien Britton, Dimitri Y. Chirgadze, Virginie Ropars, Jean‐Baptiste Charbonnier, Patrick Calsou, Amanda K. Chaplin

    Published 2025
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  20. 20
    Molecular basis of pyruvate transport and inhibition of the human mitochondrial pyruvate carrier

    Molecular basis of pyruvate transport and inhibition of the human mitochondrial pyruvate carrier by Maximilian Sichrovsky, Denis Lacabanne, Jonathan J. Ruprecht, J. L. Rana, Klaudia Stanik, Mariangela Dionysopoulou, Alice P. Sowton, Martin S. King, Scott A. Jones, Lee R. Cooper, Steven W. Hardwick, Giulia Paris, Dimitri Y. Chirgadze, Shujing Ding, Ian M. Fearnley, Shane M. Palmer, Els Pardon, Jan Steyaert, Vanessa Leone, Lucy R. Forrest, Sotiria Tavoulari, Edmund R.S. Kunji

    Published 2025
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