检索结果 - Deepali Gotur

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    MTA-Cooperative PRMT5 Inhibitors: Mechanism Switching Through Structure-Based Design

    MTA-Cooperative PRMT5 Inhibitors: Mechanism Switching Through Structure-Based Design 由 Kevin M. Cottrell, Douglas A. Whittington, Kimberly J. Briggs, Haris Jahić, Janid A. Ali, Alvaro J. Amor, Deepali Gotur, Matthew R. Tonini, Wenhai Zhang, Alan Huang, John P. Maxwell

    出版 2025
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    Artigo
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    Discovery of TNG908: A Selective, Brain Penetrant, MTA-Cooperative PRMT5 Inhibitor That Is Synthetically Lethal with <i>MTAP</i>-Deleted Cancers

    Discovery of TNG908: A Selective, Brain Penetrant, MTA-Cooperative PRMT5 Inhibitor That Is Synthetically Lethal with <i>MTAP</i>-Deleted Cancers 由 Kevin M. Cottrell, Kimberly J. Briggs, Douglas A. Whittington, Haris Jahić, Janid A. Ali, Charles B. Davis, Shanzhong Gong, Deepali Gotur, Lina Gu, Patrick McCarren, Matthew R. Tonini, Alice Tsai, Erik Wilker, Hongling Yuan, Minjie Zhang, Wenhai Zhang, Alan Huang, John P. Maxwell

    出版 2024
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    Artigo
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    Ubiquitinated PCNA Drives USP1 Synthetic Lethality in Cancer

    Ubiquitinated PCNA Drives USP1 Synthetic Lethality in Cancer 由 Antoine Simoneau, Justin L. Engel, Madhavi Bandi, Katherine Lazarides, Shangtao Liu, Samuel R. Meier, Ashley H. Choi, Hongxiang Zhang, Binzhang Shen, Lauren Martires, Deepali Gotur, Truc V. Pham, Fang Li, Lina Gu, Shanzhong Gong, Minjie Zhang, Erik Wilker, Xuewen Pan, Douglas A. Whittington, Scott Throner, John P. Maxwell, Yingnan Chen, Yi Yu, Alan Huang, Jannik N. Andersen, Tianshu Feng

    出版 2022
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    Artigo
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