檢索結果 - Deepak Sampath
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Ligand-Independent HER2/HER3/PI3K Complex Is Disrupted by Trastuzumab and Is Effectively Inhibited by the PI3K Inhibitor GDC-0941 由 Teemu T. Junttila, Robert W. Akita, Kathryn L. Parsons, Carter T. Fields, Gail D. Lewis Phillips, Lori S. Friedman, Deepak Sampath, Mark X. Sliwkowski
出版 2009Artigo -
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GDC-0941, a Novel Class I Selective PI3K Inhibitor, Enhances the Efficacy of Docetaxel in Human Breast Cancer Models by Increasing Cell Death <i>In Vitro</i> and <i>In Vivo</i> 由 Jeffrey J. Wallin, Jane Guan, Wei Wei Prior, Leslie B. Lee, Leanne Berry, Lisa D. Belmont, Hartmut Koeppen, Marcia Belvin, Lori S. Friedman, Deepak Sampath
出版 2012Artigo -
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The Bcl-2 specific BH3 mimetic ABT-199: a promising targeted therapy for t(11;14) multiple myeloma 由 Cyrille Touzeau, Christelle Dousset, Steven Le Gouill, Deepak Sampath, Joel D. Leverson, Andrew J. Souers, Sophie Maïga, Marie C. Béné, Philippe Moreau, Catherine Pellat‐Deceunynck, Martine Amiot
出版 2013Carta -
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Bcl-2/Bcl-xL Inhibition Increases the Efficacy of MEK Inhibition Alone and in Combination with PI3 Kinase Inhibition in Lung and Pancreatic Tumor Models 由 Nguyen Tan, Maureen Wong, Michelle Nannini, Rebecca Hong, Leslie B. Lee, S. Russ Price, Karen Williams, Pascal Savy, Peng Yue, Deepak Sampath, Jeffrey Settleman, Wayne J. Fairbrother, Lisa D. Belmont
出版 2013Artigo -
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Systems analysis of apoptotic priming in ovarian cancer identifies vulnerabilities and predictors of drug response 由 Ioannis K. Zervantonakis, Claudia Iavarone, Hsing‐Yu Chen, Laura M. Selfors, Sangeetha Palakurthi, Joyce F. Liu, Ronny Drapkin, Ursula A. Matulonis, Joel D. Leverson, Deepak Sampath, Gordon B. Mills, Joan S. Brugge
出版 2017Artigo -
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Predictive Biomarkers of Sensitivity to the Phosphatidylinositol 3′ Kinase Inhibitor GDC-0941 in Breast Cancer Preclinical Models 由 Carol O’Brien, Jeffrey J. Wallin, Deepak Sampath, Debraj GuhaThakurta, Heidi Savage, Elizabeth A. Punnoose, Jane Guan, Leanne Berry, Wei Wei Prior, Lukas C. Amler, Marcia Belvin, Lori S. Friedman, Mark R. Lackner
出版 2010Artigo -
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Combined MEK and BCL-2/XL Inhibition Is Effective in High-Grade Serous Ovarian Cancer Patient–Derived Xenograft Models and BIM Levels Are Predictive of Responsiveness 由 Claudia Iavarone, Ioannis K. Zervantonakis, Laura M. Selfors, Sangeetha Palakurthi, Joyce F. Liu, Ronny Drapkin, Ursula A. Matulonis, Dorothy Hallberg, Victor E. Velculescu, Joel D. Leverson, Deepak Sampath, Gordon B. Mills, Joan S. Brugge
出版 2019Artigo -
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Venetoclax combines synergistically with FLT3 inhibition to effectively target leukemic cells in FLT3-ITD+ acute myeloid leukemia models 由 Raghuveer Singh Mali, Qi Zhang, RosaAnna DeFilippis, Antonio Cavazos, Vinitha M. Kuruvilla, Jayant Raman, Vidhi Mody, Edna F. Choo, Monique Dail, Neil P. Shah, Marina Konopleva, Deepak Sampath, Elisabeth A. Lasater
出版 2020Artigo -
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Single-Cell Dynamics Determines Response to CDK4/6 Inhibition in Triple-Negative Breast Cancer 由 Uzma Asghar, Alexis R. Barr, Ros Cutts, Matthew Beaney, Irina S. Babina, Deepak Sampath, Jennifer M. Giltnane, Jennifer A. Lacap, Lisa Crocker, Amy Young, Alex Pearson, María Teresa Herrera-Abreu, Chris Bakal, Nicholas C. Turner
出版 2017Artigo -
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Dependence of Tumor Cell Lines and Patient-Derived Tumors on the NAD Salvage Pathway Renders Them Sensitive to NAMPT Inhibition with GNE-618 由 Yang Xiao, Kristi Elkins, Jenni Durieux, Leslie Lee, Jason Oeh, Lulu Yang, Xiaorong Liang, Chris DelNagro, Jarrod R. Tremayne, Mandy Kwong, Bianca M. Liederer, Peter K. Jackson, Lisa D. Belmont, Deepak Sampath, Thomas O’Brien
出版 2013Artigo
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Enzyme