Výsledky vyhledávání - Deepak Sampath

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  1. 1
    Cyr61, a Member of the CCN Family, Is Required for MCF-7 Cell Proliferation: Regulation by 17β-Estradiol and Overexpression in Human Breast Cancer

    Cyr61, a Member of the CCN Family, Is Required for MCF-7 Cell Proliferation: Regulation by 17β-Estradiol and Overexpression in Human Breast Cancer Autor Deepak Sampath, Richard C. Winneker, Zhiming Zhang

    Vydáno 2001
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    Artigo
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  2. 2
    Uncoupling of chondroitin sulfate glycosaminoglycan synthesis by brefeldin A.

    Uncoupling of chondroitin sulfate glycosaminoglycan synthesis by brefeldin A. Autor Robert C. Spiro, Hudson H. Freeze, Deepak Sampath, Jonathan Garcia

    Vydáno 1991
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    Artigo
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  3. 3
    Constitutive activation of an epithelial signal transducer and activator of transcription (STAT) pathway in asthma

    Constitutive activation of an epithelial signal transducer and activator of transcription (STAT) pathway in asthma Autor Deepak Sampath, Mario Castro, Dwight C. Look, Michael J. Holtzman

    Vydáno 1999
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  4. 4
    Patterns for RANTES Secretion and Intercellular Adhesion Molecule 1 Expression Mediate Transepithelial T Cell Traffic Based on Analyses In Vitro and In Vivo

    Patterns for RANTES Secretion and Intercellular Adhesion Molecule 1 Expression Mediate Transepithelial T Cell Traffic Based on Analyses In Vitro and In Vivo Autor Masahiko Taguchi, Deepak Sampath, Takeharu Koga, Mario Castro, Dwight C. Look, Shin Nakajima, Michael J. Holtzman

    Vydáno 1998
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  5. 5
    Isoform-Specific Phosphoinositide 3-Kinase Inhibitors Exert Distinct Effects in Solid Tumors

    Isoform-Specific Phosphoinositide 3-Kinase Inhibitors Exert Distinct Effects in Solid Tumors Autor Kyle A. Edgar, Jeffrey J. Wallin, Megan Berry, Leslie B. Lee, Wei Wei Prior, Deepak Sampath, Lori S. Friedman, Marcia Belvin

    Vydáno 2010
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  6. 6
    Navitoclax Enhances the Efficacy of Taxanes in Non–Small Cell Lung Cancer Models

    Navitoclax Enhances the Efficacy of Taxanes in Non–Small Cell Lung Cancer Models Autor Nguyen Tan, Mehnaz Malek, Jiping Zha, Yue Peng, Robert Kassees, Leanne Berry, Wayne J. Fairbrother, Deepak Sampath, Lisa D. Belmont

    Vydáno 2011
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  7. 7
    Found in Translation: How Preclinical Research Is Guiding the Clinical Development of the BCL2-Selective Inhibitor Venetoclax

    Found in Translation: How Preclinical Research Is Guiding the Clinical Development of the BCL2-Selective Inhibitor Venetoclax Autor Joel D. Leverson, Deepak Sampath, Andrew J. Souers, Saul H. Rosenberg, Wayne J. Fairbrother, Martine Amiot, Marina Konopleva, Anthony Letai

    Vydáno 2017
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  8. 8
    Ligand-Independent HER2/HER3/PI3K Complex Is Disrupted by Trastuzumab and Is Effectively Inhibited by the PI3K Inhibitor GDC-0941

    Ligand-Independent HER2/HER3/PI3K Complex Is Disrupted by Trastuzumab and Is Effectively Inhibited by the PI3K Inhibitor GDC-0941 Autor Teemu T. Junttila, Robert W. Akita, Kathryn L. Parsons, Carter T. Fields, Gail D. Lewis Phillips, Lori S. Friedman, Deepak Sampath, Mark X. Sliwkowski

    Vydáno 2009
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  9. 9
    Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathway

    Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathway Autor Guanglei Zhuang, Xiumin Wu, Zhaoshi Jiang, Ian Kasman, Jenny Yao, Yinghui Guan, Jason Oeh, Zora Modrušan, Carlos Bais, Deepak Sampath, Napoleone Ferrara

    Vydáno 2012
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  10. 10
    GDC-0941, a Novel Class I Selective PI3K Inhibitor, Enhances the Efficacy of Docetaxel in Human Breast Cancer Models by Increasing Cell Death <i>In Vitro</i> and <i>In Vivo</i>

    GDC-0941, a Novel Class I Selective PI3K Inhibitor, Enhances the Efficacy of Docetaxel in Human Breast Cancer Models by Increasing Cell Death <i>In Vitro</i> and <i>In Vivo</i> Autor Jeffrey J. Wallin, Jane Guan, Wei Wei Prior, Leslie B. Lee, Leanne Berry, Lisa D. Belmont, Hartmut Koeppen, Marcia Belvin, Lori S. Friedman, Deepak Sampath

    Vydáno 2012
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  11. 11
    Cotargeting BCL-2 and PI3K Induces BAX-Dependent Mitochondrial Apoptosis in AML Cells

    Cotargeting BCL-2 and PI3K Induces BAX-Dependent Mitochondrial Apoptosis in AML Cells Autor Mohamed Rahmani, Jewel Nkwocha, Elisa Hawkins, Xin‐Yan Pei, Rebecca E. Parker, Maciej Kmieciak, Joel D. Leverson, Deepak Sampath, Andrea Ferreira‐Gonzalez, Steven Grant

    Vydáno 2018
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  12. 12
    The Bcl-2 specific BH3 mimetic ABT-199: a promising targeted therapy for t(11;14) multiple myeloma

    The Bcl-2 specific BH3 mimetic ABT-199: a promising targeted therapy for t(11;14) multiple myeloma Autor Cyrille Touzeau, Christelle Dousset, Steven Le Gouill, Deepak Sampath, Joel D. Leverson, Andrew J. Souers, Sophie Maïga, Marie C. Béné, Philippe Moreau, Catherine Pellat‐Deceunynck, Martine Amiot

    Vydáno 2013
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  13. 13
    Bcl-2/Bcl-xL Inhibition Increases the Efficacy of MEK Inhibition Alone and in Combination with PI3 Kinase Inhibition in Lung and Pancreatic Tumor Models

    Bcl-2/Bcl-xL Inhibition Increases the Efficacy of MEK Inhibition Alone and in Combination with PI3 Kinase Inhibition in Lung and Pancreatic Tumor Models Autor Nguyen Tan, Maureen Wong, Michelle Nannini, Rebecca Hong, Leslie B. Lee, S. Russ Price, Karen Williams, Pascal Savy, Peng Yue, Deepak Sampath, Jeffrey Settleman, Wayne J. Fairbrother, Lisa D. Belmont

    Vydáno 2013
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  14. 14
    Systems analysis of apoptotic priming in ovarian cancer identifies vulnerabilities and predictors of drug response

    Systems analysis of apoptotic priming in ovarian cancer identifies vulnerabilities and predictors of drug response Autor Ioannis K. Zervantonakis, Claudia Iavarone, Hsing‐Yu Chen, Laura M. Selfors, Sangeetha Palakurthi, Joyce F. Liu, Ronny Drapkin, Ursula A. Matulonis, Joel D. Leverson, Deepak Sampath, Gordon B. Mills, Joan S. Brugge

    Vydáno 2017
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  15. 15
    Preclinical efficacy of MEK inhibition in Nras-mutant AML

    Preclinical efficacy of MEK inhibition in Nras-mutant AML Autor Michael R. Burgess, Eugene Hwang, Ari Firestone, Tannie Q. Huang, Jin Xu, Johannes Zuber, Natacha Bohin, Tiffany Wen, Scott C. Kogan, Kevin M. Haigis, Deepak Sampath, Scott W. Lowe, Kevin Shannon, Qing Li

    Vydáno 2014
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  16. 16
    Predictive Biomarkers of Sensitivity to the Phosphatidylinositol 3′ Kinase Inhibitor GDC-0941 in Breast Cancer Preclinical Models

    Predictive Biomarkers of Sensitivity to the Phosphatidylinositol 3′ Kinase Inhibitor GDC-0941 in Breast Cancer Preclinical Models Autor Carol O’Brien, Jeffrey J. Wallin, Deepak Sampath, Debraj GuhaThakurta, Heidi Savage, Elizabeth A. Punnoose, Jane Guan, Leanne Berry, Wei Wei Prior, Lukas C. Amler, Marcia Belvin, Lori S. Friedman, Mark R. Lackner

    Vydáno 2010
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  17. 17
    Combined MEK and BCL-2/XL Inhibition Is Effective in High-Grade Serous Ovarian Cancer Patient–Derived Xenograft Models and BIM Levels Are Predictive of Responsiveness

    Combined MEK and BCL-2/XL Inhibition Is Effective in High-Grade Serous Ovarian Cancer Patient–Derived Xenograft Models and BIM Levels Are Predictive of Responsiveness Autor Claudia Iavarone, Ioannis K. Zervantonakis, Laura M. Selfors, Sangeetha Palakurthi, Joyce F. Liu, Ronny Drapkin, Ursula A. Matulonis, Dorothy Hallberg, Victor E. Velculescu, Joel D. Leverson, Deepak Sampath, Gordon B. Mills, Joan S. Brugge

    Vydáno 2019
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  18. 18
    Venetoclax combines synergistically with FLT3 inhibition to effectively target leukemic cells in FLT3-ITD+ acute myeloid leukemia models

    Venetoclax combines synergistically with FLT3 inhibition to effectively target leukemic cells in FLT3-ITD+ acute myeloid leukemia models Autor Raghuveer Singh Mali, Qi Zhang, RosaAnna DeFilippis, Antonio Cavazos, Vinitha M. Kuruvilla, Jayant Raman, Vidhi Mody, Edna F. Choo, Monique Dail, Neil P. Shah, Marina Konopleva, Deepak Sampath, Elisabeth A. Lasater

    Vydáno 2020
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  19. 19
    Single-Cell Dynamics Determines Response to CDK4/6 Inhibition in Triple-Negative Breast Cancer

    Single-Cell Dynamics Determines Response to CDK4/6 Inhibition in Triple-Negative Breast Cancer Autor Uzma Asghar, Alexis R. Barr, Ros Cutts, Matthew Beaney, Irina S. Babina, Deepak Sampath, Jennifer M. Giltnane, Jennifer A. Lacap, Lisa Crocker, Amy Young, Alex Pearson, María Teresa Herrera-Abreu, Chris Bakal, Nicholas C. Turner

    Vydáno 2017
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  20. 20
    Dependence of Tumor Cell Lines and Patient-Derived Tumors on the NAD Salvage Pathway Renders Them Sensitive to NAMPT Inhibition with GNE-618

    Dependence of Tumor Cell Lines and Patient-Derived Tumors on the NAD Salvage Pathway Renders Them Sensitive to NAMPT Inhibition with GNE-618 Autor Yang Xiao, Kristi Elkins, Jenni Durieux, Leslie Lee, Jason Oeh, Lulu Yang, Xiaorong Liang, Chris DelNagro, Jarrod R. Tremayne, Mandy Kwong, Bianca M. Liederer, Peter K. Jackson, Lisa D. Belmont, Deepak Sampath, Thomas O’Brien

    Vydáno 2013
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