Resultats de la cerca - Dean W. Hum

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  1. 1
    Regulation of the Human P450scc Gene by Steroidogenic Factor 1 Is Mediated by CBP/p300

    Regulation of the Human P450scc Gene by Steroidogenic Factor 1 Is Mediated by CBP/p300 per Didier Monté, Frédérique Dewitte, Dean W. Hum

    Publicat 1998
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  2. 2
    Isolation and Characterization of a Novel cDNA Encoding a Human UDP-Glucuronosyltransferase Active on C19 Steroids

    Isolation and Characterization of a Novel cDNA Encoding a Human UDP-Glucuronosyltransferase Active on C19 Steroids per Martin Beaulieu, Eric Lávesque, Dean W. Hum, Alain Bálanger

    Publicat 1996
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  3. 3
    Transcription of the Human Genes for Cytochrome P450scc and P450c17 Is Regulated Differently in Human Adrenal NCI-H295 Cells Than in Mouse Adrenal Y1 Cells<sup>1</sup>

    Transcription of the Human Genes for Cytochrome P450scc and P450c17 Is Regulated Differently in Human Adrenal NCI-H295 Cells Than in Mouse Adrenal Y1 Cells<sup>1</sup> per Henry Rodriguez, Dean W. Hum, Bart Staels, Walter L. Miller

    Publicat 1997
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  4. 4
    Primary structure of a human trifunctional enzyme. Isolation of a cDNA encoding methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase-formyltetrahydrofolate synthetase.

    Primary structure of a human trifunctional enzyme. Isolation of a cDNA encoding methylenetetrahydrofolate dehydrogenase-methenyltetrahydrofolate cyclohydrolase-formyltetrahydrofola... per Dean W. Hum, Angus Bell, Rima Rozen, Robert E. MacKenzie

    Publicat 1988
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  5. 5
    The Monkey and Human Uridine Diphosphate-Glucuronosyltransferase UGT1A9, Expressed in Steroid Target Tissues, Are Estrogen-Conjugating Enzymes*

    The Monkey and Human Uridine Diphosphate-Glucuronosyltransferase UGT1A9, Expressed in Steroid Target Tissues, Are Estrogen-Conjugating Enzymes* per Caroline Albert, Michel Vallée, Guillaume Beaudry, Alain Bélanger, Dean W. Hum

    Publicat 1999
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  6. 6
    Relative Enzymatic Activity, Protein Stability, and Tissue Distribution of Human Steroid-Metabolizing UGT2B Subfamily Members**This work was supported by the Medical Research Council of Canada, the Fonds de la Recherche en Santé du Québec, and Endorecherche.

    Relative Enzymatic Activity, Protein Stability, and Tissue Distribution of Human Steroid-Metabolizing UGT2B Subfamily Members**This work was supported by the Medical Research Counc... per David Turgeon, Jean-Sébastien Carrier, Éric Lévesque, Dean W. Hum, Alain Bélanger

    Publicat 2001
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  7. 7
    Differential Regulation of Two Uridine Diphospho-Glucuronosyltransferases, UGT2B15 and UGT2B17, in Human Prostate LNCaP Cells<sup>1</sup>

    Differential Regulation of Two Uridine Diphospho-Glucuronosyltransferases, UGT2B15 and UGT2B17, in Human Prostate LNCaP Cells<sup>1</sup> per Chantal Guillemette, Éric Lévesque, Martin Beaulieu, David Turgeon, Dean W. Hum, Alain Bélanger

    Publicat 1997
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  8. 8
    The Liver X Receptor Ligand T0901317 Down-regulates APOA5 Gene Expression through Activation of SREBP-1c

    The Liver X Receptor Ligand T0901317 Down-regulates APOA5 Gene Expression through Activation of SREBP-1c per Heidelinde Jäkel, Maxime Nowak, Emanuelle Moitrot, Hélène Dehondt, Dean W. Hum, L Pennacchio, Jamila Fruchart‐Najib, Jean‐Charles Fruchart

    Publicat 2004
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  9. 9
    Differential Regulation of Insulin-like Growth Factor-I (IGF-I) Receptor Gene Expression by IGF-I and Basic Fibroblastic Growth Factor

    Differential Regulation of Insulin-like Growth Factor-I (IGF-I) Receptor Gene Expression by IGF-I and Basic Fibroblastic Growth Factor per Catalina Hernández‐Sánchez, Haim Werner, Charles T. Roberts, Emily Jane Woo, Dean W. Hum, Stephen M. Rosenthal, Derek LeRoith

    Publicat 1997
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  10. 10
    Phosphorylation of Farnesoid X Receptor by Protein Kinase C Promotes Its Transcriptional Activity

    Phosphorylation of Farnesoid X Receptor by Protein Kinase C Promotes Its Transcriptional Activity per Romain Gineste, Audrey Sirvent, Réjane Paumelle, Stéphane Helleboid, Alexis Aquilina, Raphaël Darteil, Dean W. Hum, Jean‐Charles Fruchart, Bart Staels

    Publicat 2008
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  11. 11
    Pan-PPAR Modulation Effectively Protects APP/PS1 Mice from Amyloid Deposition and Cognitive Deficits

    Pan-PPAR Modulation Effectively Protects APP/PS1 Mice from Amyloid Deposition and Cognitive Deficits per Markus P. Kummer, Rafael Schwarzenberger, Sakina Sayah‐Jeanne, Mathieu Dubernet, Robert Walczak, Dean W. Hum, Stephanie Schwartz, Daisy Axt, Michael T. Heneka

    Publicat 2014
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  12. 12
    The Identification of Naturally Occurring Neoruscogenin as a Bioavailable, Potent, and High-Affinity Agonist of the Nuclear Receptor RORα (NR1F1)

    The Identification of Naturally Occurring Neoruscogenin as a Bioavailable, Potent, and High-Affinity Agonist of the Nuclear Receptor RORα (NR1F1) per Stéphane Helleboid, Christian Haug, Kai Lamottke, Zhou Yijun, Jianbing Wei, Sébastien Daix, Linda Cambula, Géraldine Rigou, Dean W. Hum, Robert Walczak

    Publicat 2013
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  13. 13
    Bile acid-activated nuclear receptor FXR suppresses apolipoprotein A-I transcription via a negative FXR response element

    Bile acid-activated nuclear receptor FXR suppresses apolipoprotein A-I transcription via a negative FXR response element per Thierry Claudel, Ekkehard Sturm, Hélène Duez, Inès Pineda‐Torra, Audrey Sirvent, V. P. Kosykh, Jean‐Charles Fruchart, Jean Dallongeville, Dean W. Hum, Folkert Kuipers, Bart Staels

    Publicat 2002
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  14. 14
    Bile acid-activated nuclear receptor FXR suppresses apolipoprotein A-I transcription via a negative FXR response element

    Bile acid-activated nuclear receptor FXR suppresses apolipoprotein A-I transcription via a negative FXR response element per Thierry Claudel, Ekkehard Sturm, Hélène Duez, Inès Pineda‐Torra, Audrey Sirvent, V. P. Kosykh, Jean‐Charles Fruchart, Jean Dallongeville, Dean W. Hum, Folkert Kuipers, Bart Staels

    Publicat 2002
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  15. 15
    NIS2+™, an optimisation of the blood-based biomarker NIS4® technology for the detection of at-risk NASH: A prospective derivation and validation study

    NIS2+™, an optimisation of the blood-based biomarker NIS4® technology for the detection of at-risk NASH: A prospective derivation and validation study per Stephen A. Harrison, Vlad Ratziu, Jérémy Magnanensi, Yacine Hajji, Sylvie Deledicque, Zouher Majd, Christian Rosenquist, Dean W. Hum, Bart Staels, Quentin M. Anstee, Arun J. Sanyal

    Publicat 2023
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  16. 16
    NIS2+TM as a screening tool to optimize patient selection in metabolic dysfunction-associated steatohepatitis clinical trials

    NIS2+TM as a screening tool to optimize patient selection in metabolic dysfunction-associated steatohepatitis clinical trials per Vlad Ratziu, Stephen A. Harrison, Yacine Hajji, Jérémy Magnanensi, Stéphanie Petit, Zouher Majd, Elodie Delecroix, Christian Rosenquist, Dean W. Hum, Bart Staels, Quentin M. Anstee, Arun J. Sanyal

    Publicat 2023
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  17. 17
    A blood-based biomarker panel (NIS4) for non-invasive diagnosis of non-alcoholic steatohepatitis and liver fibrosis: a prospective derivation and global validation study

    A blood-based biomarker panel (NIS4) for non-invasive diagnosis of non-alcoholic steatohepatitis and liver fibrosis: a prospective derivation and global validation study per Stephen Harrison, Vlad Ratziu, Jérôme Boursier, Sven Francque, Pierre Bédossa, Zouher Majd, G. Cordonnier, Fouad Ben Sudrik, Raphaël Darteil, Roman Liebe, Jérémy Magnanensi, Yacine Hajji, John Brozek, A. Roudot, Bart Staels, Dean W. Hum, S. Megnien, Suneil Hosmane, Noémie Dam, Pierre Chaumat, Rémy Hanf, Quentin M. Anstee, Arun J. Sanyal

    Publicat 2020
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  18. 18
    Elafibranor, an Agonist of the Peroxisome Proliferator−Activated Receptor−α and −δ, Induces Resolution of Nonalcoholic Steatohepatitis Without Fibrosis Worsening

    Elafibranor, an Agonist of the Peroxisome Proliferator−Activated Receptor−α and −δ, Induces Resolution of Nonalcoholic Steatohepatitis Without Fibrosis Worsening per Vlad Ratziu, Stephen A. Harrison, Sven Francque, Pierre Bédossa, Philippe Lehert, Lawrence Serfaty, Manuel Romero‐Gómez, Jérôme Boursier, Manal F. Abdelmalek, Steve Caldwell, Joost P.H. Drenth, Quentin M. Anstee, Dean W. Hum, Rémy Hanf, A. Roudot, S. Megnien, Bart Staels, Arun J. Sanyal, Philippe Mathurin, Jérôme Gournay, Eric Nguyen‐Khac, Victor de Lédinghen, Dominique Larrey, Albert Tran, Marc Bourlière, M. Maynard-Muet, Tarik Asselah, Jean Henrion, Frederik Nevens, David Cassiman, Anja Geerts, Christophe Moreno, Ulrich Beuers, Peter R. Galle, U. Spengler, Elisabetta Bugianesi, Antonio Craxı̀, M. Angélico, Silvia Fargion, M Voiculescu, Liliana Gheorghe, Liliana Preoțescu, Juan Caballería, Raúl J. Andrade, Javier Crespo, J.L. Callera, Aftab Ala, Guruprasad P. Aithal, George Abouda, Velimir A. Luketic, Mao-Yu Huang, Stuart C. Gordon, Paul J. Pockros, Fred Poordad, Nathan J. Shores, Martin Moehlen, Kiran Bambha, Virginia Clark, Sanjaya K. Satapathy, Samir Parekh, R.K. Reddy, Muhammad Y. Sheikh, Gyöngyi Szabó, John M. Vierling, Timothy E. Foster, Guillermo E. Umpierrez, Chih‐Jen Chang, Terry Box, Juan F. Gallegos‐Orozco

    Publicat 2016
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