Resultats de la cerca - Dean Clift

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  1. 1
    Restarting life: fertilization and the transition from meiosis to mitosis

    Restarting life: fertilization and the transition from meiosis to mitosis per Dean Clift, Melina Schuh

    Publicat 2013
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  2. 2
    A three-step MTOC fragmentation mechanism facilitates bipolar spindle assembly in mouse oocytes

    A three-step MTOC fragmentation mechanism facilitates bipolar spindle assembly in mouse oocytes per Dean Clift, Melina Schuh

    Publicat 2015
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  3. 3
    The Role of Shugoshin in Meiotic Chromosome Segregation

    The Role of Shugoshin in Meiotic Chromosome Segregation per Dean Clift, Adèle L. Marston

    Publicat 2011
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  4. 4
    Shugoshin prevents cohesin cleavage by PP2A<sup>Cdc55</sup>-dependent inhibition of separase

    Shugoshin prevents cohesin cleavage by PP2A<sup>Cdc55</sup>-dependent inhibition of separase per Dean Clift, Farid Bizzari, Adèle L. Marston

    Publicat 2009
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  5. 5
    RING domains act as both substrate and enzyme in a catalytic arrangement to drive self-anchored ubiquitination

    RING domains act as both substrate and enzyme in a catalytic arrangement to drive self-anchored ubiquitination per L. Kiss, Dean Clift, Nadine Renner, David Neuhaus, Leo C. James

    Publicat 2021
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  6. 6
    Acute and rapid degradation of endogenous proteins by Trim-Away

    Acute and rapid degradation of endogenous proteins by Trim-Away per Dean Clift, Chun So, William A. McEwan, Leo C. James, Melina Schuh

    Publicat 2018
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  7. 7
    A Method for the Acute and Rapid Degradation of Endogenous Proteins

    A Method for the Acute and Rapid Degradation of Endogenous Proteins per Dean Clift, William A. McEwan, Larisa I. Labzin, Vera Konieczny, Binyam Mogessie, Leo C. James, Melina Schuh

    Publicat 2017
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  8. 8
    A liquid-like spindle domain promotes acentrosomal spindle assembly in mammalian oocytes

    A liquid-like spindle domain promotes acentrosomal spindle assembly in mammalian oocytes per Chun So, K. Bianka Seres, Anna M. Steyer, Eike Urs Mönnich, Dean Clift, Anastasija Pejkovska, Wiebke Möbius, Melina Schuh

    Publicat 2019
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  9. 9
    Cytosolic Fc receptor TRIM21 inhibits seeded tau aggregation

    Cytosolic Fc receptor TRIM21 inhibits seeded tau aggregation per William A. McEwan, Benjamin Falcon, Marina Vaysburd, Dean Clift, Adrian L. Oblak, Bernardino Ghetti, Michel Goedert, Leo C. James

    Publicat 2017
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  10. 10
    Antibody and DNA sensing pathways converge to activate the inflammasome during primary human macrophage infection

    Antibody and DNA sensing pathways converge to activate the inflammasome during primary human macrophage infection per Larisa I. Labzin, Maria Bottermann, Pablo Rodríguez-Silvestre, Stian Foss, Jan Terje Andersen, Marina Vaysburd, Dean Clift, Leo C. James

    Publicat 2019
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  11. 11
    Shugoshin biases chromosomes for biorientation through condensin recruitment to the pericentromere

    Shugoshin biases chromosomes for biorientation through condensin recruitment to the pericentromere per Kitty F. Verzijlbergen, Olga O. Nerusheva, David A. Kelly, Alastair Kerr, Dean Clift, Flávia de Lima Alves, Juri Rappsilber, Adèle L. Marston

    Publicat 2014
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  12. 12
    Trim-Away ubiquitinates and degrades lysine-less and N-terminally acetylated substrates

    Trim-Away ubiquitinates and degrades lysine-less and N-terminally acetylated substrates per L. Kiss, Tyler Rhinesmith, Jakub Lupták, Claire F. Dickson, Jonas Weidenhausen, Shannon Smyly, Ji‐Chun Yang, Sarah Maslen, Irmgard Sinning, David Neuhaus, Dean Clift, Leo C. James

    Publicat 2023
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  13. 13
    Antibodies targeting the Crimean-Congo Hemorrhagic Fever Virus nucleoprotein protect via TRIM21

    Antibodies targeting the Crimean-Congo Hemorrhagic Fever Virus nucleoprotein protect via TRIM21 per Shanna Leventhal, Thomas C. Bisom, Dean Clift, Deepashri Rao, Kimberly Meade‐White, Carl Shaia, Justin Murray, Evan A. Mihalakakos, Troy Hinkley, Steven J. Reynolds, Sonja M. Best, Jesse H. Erasmus, Leo C. James, Heinz Feldmann, David W. Hawman

    Publicat 2024
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  14. 14
    Anti-commensal IgG Drives Intestinal Inflammation and Type 17 Immunity in Ulcerative Colitis

    Anti-commensal IgG Drives Intestinal Inflammation and Type 17 Immunity in Ulcerative Colitis per Tomas Castro‐Dopico, Thomas W. Dennison, John R. Ferdinand, Rebeccah J. Mathews, Aaron Fleming, Dean Clift, Benjamin Stewart, Chenzhi Jing, Konstantina Strongili, Larisa I. Labzin, Edward J M Monk, Kourosh Saeb‐Parsy, Clare Bryant, Simon Clare, Miles Parkes, Menna R. Clatworthy

    Publicat 2019
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  15. 15
    Complement C4 Prevents Viral Infection through Capsid Inactivation

    Complement C4 Prevents Viral Infection through Capsid Inactivation per Maria Bottermann, Stian Foss, Sarah Caddy, Dean Clift, Laurens M. van Tienen, Marina Vaysburd, James Cruickshank, Kevin O’Connell, Jessica Clark, Keith Mayes, Katie Higginson, Heidrun Elisabeth Lode, Martin B. McAdam, Inger Sandlie, Jan Terje Andersen, Leo C. James

    Publicat 2019
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  16. 16
    Target-induced clustering activates Trim-Away of pathogens and proteins

    Target-induced clustering activates Trim-Away of pathogens and proteins per Jingwei Zeng, Ana Filipa Santos, Aamir S. Mukadam, Mariana Osswald, David A. Jacques, Claire F. Dickson, Stephen H. McLaughlin, C.M. Johnson, L. Kiss, Jakub Lupták, Nadine Renner, Marina Vaysburd, William A. McEwan, Eurico Morais‐de‐Sá, Dean Clift, Leo C. James

    Publicat 2021
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  17. 17
    A TRIM21-based bioPROTAC highlights the therapeutic benefit of HuR degradation

    A TRIM21-based bioPROTAC highlights the therapeutic benefit of HuR degradation per Alice Fletcher, Dean Clift, Emma de Vries, Sergio Martínez Cuesta, Timothy Malcolm, Francesco Meghini, Raghothama Chaerkady, Junmin Wang, Abby J. Chiang, Shao Huan Samuel Weng, Jonathan Tart, Edmond Wong, Gerard G. Donohoe, Philip B. Rawlins, Euan Gordon, Jonathan D. Taylor, Leo C. James, James Hunt

    Publicat 2023
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  18. 18
    Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome

    Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome per Gabriel Balmus, Delphine Larrieu, Ana C. Barros, Casey Collins, Monica Abrudan, Mehmet Demir, Nicola J. Geisler, Christopher J. Lelliott, Jacqueline K. White, Natasha A. Karp, James Atkinson, Andrea Kirton, Matt Jacobsen, Dean Clift, Raphaël Rodriguez, Carl Shannon, Mark Sanderson, Amy Gates, Joshua Dench, Valerie E. Vancollie, Catherine McCarthy, Selina Pearson, Emma L. Cambridge, Christopher Isherwood, Heather Wilson, Evelyn Grau, Antonella Galli, Yvette Hooks, Catherine Tudor, Angela L. Green, Fiona Kussy, Elizabeth Tuck, Emma Siragher, Robbie S. B. McLaren, Agnieszka Świątkowska, Susana Caetano, Cecilia Mazzeo, Monika Dabrowska, Simon A. Maguire, David Lafont, Lauren F. E. Anthony, Maksymilian T. Sumowski, James Bussell, Caroline Sinclair, Ellen Brown, Brendan Doe, Hannah Wardle‐Jones, Nicola Griggs, Mike Woods, Harun Kundi, George McConnell, Joanne Doran, Mark Griffiths, Christian Kipp, S. Holroyd, David J. Gannon, Rafael Alcántara, Ramiro Ramírez‐Solis, Joanna Bottomley, Catherine Ingle, Victoria Ross, Daniel M. Barrett, Debarati Sethi, Diane Gleeson, Jonathan Burvill, Radka Platte, Edward Ryder, Elodie Sins, Evelina Miklejewska, Dominique Von Schiller, Graham Duddy, Jana Urbanová, Katharina Boroviak, Maria Imran, Shalini Kamu Reddy, David J. Adams, Stephen P. Jackson

    Publicat 2018
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