Søgeresultater - David W. Piotrowski

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  1. 1
    The use of plasma aldosterone and urinary sodium to potassium ratio as translatable quantitative biomarkers of mineralocorticoid receptor antagonism

    The use of plasma aldosterone and urinary sodium to potassium ratio as translatable quantitative biomarkers of mineralocorticoid receptor antagonism af Rena J Eudy, Vaishali Sahasrabudhe, Kevin Sweeney, Meera Tugnait, Amanda King‐Ahmad, Kristen Near, Paula M. Loria, Mary Ellen Banker, David W. Piotrowski, Carine M. Boustany‐Kari

    Udgivet 2011
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  2. 2
    A Novel Positive Allosteric Modulator of the α7 Neuronal Nicotinic Acetylcholine Receptor:<i>In Vitro</i>and<i>In Vivo</i>Characterization

    A Novel Positive Allosteric Modulator of the α7 Neuronal Nicotinic Acetylcholine Receptor:<i>In Vitro</i>and<i>In Vivo</i>Characterization af Raymond S Hurst, Mihály Hajós, M. Raggenbass, Theron M. Wall, Nicole R. Higdon, Judy A. Lawson, Karen L. Rutherford-Root, Mitchell B. Berkenpas, William E. Hoffmann, David W. Piotrowski, Vincent E. Groppi, Geraldine Allaman, Roch Ogier, Sonia Bertrand, Daniel Bertrand, Stephen P. Arnerić

    Udgivet 2005
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  3. 3
    RASS‐Enabled S/P−C and S−N Bond Formation for DEL Synthesis

    RASS‐Enabled S/P−C and S−N Bond Formation for DEL Synthesis af Dillon T. Flood, Xue‐Jing Zhang, Xiang Fu, Zhenxiang Zhao, Shota Asai, Brittany B. Sanchez, Emily Sturgell, Julien C. Vantourout, Paul Richardson, Mark E. Flanagan, David W. Piotrowski, Dominik K. Kölmel, Jinqiao Wan, Mei‐Hsuan Tsai, Jason S. Chen, Phil S. Baran, Philip E. Dawson

    Udgivet 2020
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  4. 4
    Expanding Reactivity in DNA-Encoded Library Synthesis via Reversible Binding of DNA to an Inert Quaternary Ammonium Support

    Expanding Reactivity in DNA-Encoded Library Synthesis via Reversible Binding of DNA to an Inert Quaternary Ammonium Support af Dillon T. Flood, Shota Asai, Xue‐Jing Zhang, Jie Wang, Leonard Yoon, Zoë C. Adams, Blythe C. Dillingham, Brittany B. Sanchez, Julien C. Vantourout, Mark E. Flanagan, David W. Piotrowski, Paul Richardson, Samantha A. Green, Ryan A. Shenvi, Jason S. Chen, Phil S. Baran, Philip E. Dawson

    Udgivet 2019
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  5. 5
    Discovery of PF-04620110, a Potent, Selective, and Orally Bioavailable Inhibitor of DGAT-1

    Discovery of PF-04620110, a Potent, Selective, and Orally Bioavailable Inhibitor of DGAT-1 af Robert L. Dow, Jiancheng Li, Michael P. Pence, E. Michael Gibbs, Jennifer L. LaPerle, John Litchfield, David W. Piotrowski, Michael J. Munchhof, Tara B. Manion, William J. Zavadoski, Gregory S. Walker, R. Kirk McPherson, Susan Tapley, Eliot Sugarman, Angel Guzmán-Pérez, Paul DaSilva‐Jardine

    Udgivet 2011
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  6. 6
    Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain

    Selective stalling of human translation through small-molecule engagement of the ribosome nascent chain af Nathanael G. Lintner, Kim F. McClure, Donna N. Petersen, Allyn T. Londregan, David W. Piotrowski, Liuqing Wei, Jun Xiao, Michael W. Bolt, Paula M. Loria, Bruce A. Maguire, Kieran F. Geoghegan, Austin Huang, Tim Rolph, Spiros Liras, Jennifer A. Doudna, Robert Dullea, J.H.D. Cate

    Udgivet 2017
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  7. 7
    Identification of Tetrahydropyrido[4,3-<i>d</i>]pyrimidine Amides as a New Class of Orally Bioavailable TGR5 Agonists

    Identification of Tetrahydropyrido[4,3-<i>d</i>]pyrimidine Amides as a New Class of Orally Bioavailable TGR5 Agonists af David W. Piotrowski, Kentaro Futatsugi, Joseph S. Warmus, Suvi T. M. Orr, Kevin D. Freeman‐Cook, Allyn T. Londregan, Liuqing Wei, Sandra M. Jennings, Michael Herr, Steven B. Coffey, Wenhua Jiao, Gregory Storer, David Hepworth, Jian Wang, Sophie Y. Lavergne, Janice E. Chin, John R. Hadcock, Martin Brenner, Angela Wolford, Ann M. Janssen, Nicole Roush, Joanne Buxton, Terri Hinchey, Amit S. Kalgutkar, Raman Sharma, Declan Flynn

    Udgivet 2012
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  8. 8
    A Small-Molecule Oral Agonist of the Human Glucagon-like Peptide-1 Receptor

    A Small-Molecule Oral Agonist of the Human Glucagon-like Peptide-1 Receptor af David A. Griffith, David J. Edmonds, Jean‐Philippe Fortin, Amit S. Kalgutkar, J. Brent Kuzmiski, Paula M. Loria, Aditi R. Saxena, Scott W. Bagley, Clare Buckeridge, John M. Curto, David R. Derksen, João M. Dias, Matthew C. Griffor, Seungil Han, V. Margaret Jackson, Margaret S. Landis, Daniel J. Lettiere, Chris Limberakis, Yuhang Liu, Alan M. Mathiowetz, Jayesh C. Patel, David W. Piotrowski, David A. Price, Roger B. Ruggeri, David A. Tess

    Udgivet 2022
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  9. 9
    PF-07059013: A Noncovalent Modulator of Hemoglobin for Treatment of Sickle Cell Disease

    PF-07059013: A Noncovalent Modulator of Hemoglobin for Treatment of Sickle Cell Disease af Ariamala Gopalsamy, Ann Aulabaugh, Amey Barakat, Kevin Beaumont, Shawn Cabral, Daniel P. Canterbury, Agustin Casimiro‐Garcia, Jeanne S. Chang, Ming Z. Chen, Chulho Choi, Robert L. Dow, Olugbeminiyi Fadeyi, Xidong Feng, Scott P. France, Roger M. Howard, Jay M. Janz, J. Jasti, Reema Jasuja, Lyn H. Jones, Amanda King‐Ahmad, Kelly M. Knee, Jeffrey T. Kohrt, Chris Limberakis, Spiros Liras, Carlos A. Martínez, Kim F. McClure, Arjun Narayanan, Jatin Narula, Jonathan J. Novak, Thomas N. O’Connell, Mihir D. Parikh, David W. Piotrowski, Olga Plotnikova, Ralph P. Robinson, Parag V. Sahasrabudhe, Raman Sharma, Benjamin A. Thuma, Dipy M. Vasa, Liuqing Wei, Anne Wenzel, Jane M. Withka, Jun Xiao, Hatice G. Yayla

    Udgivet 2020
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