Kết quả tìm kiếm - David W. Clark

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  1. 1
    Aldehyde dehydrogenases in cancer stem cells: potential as therapeutic targets

    Aldehyde dehydrogenases in cancer stem cells: potential as therapeutic targets Bằng David W. Clark, Komaraiah Palle

    Được phát hành 2016
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    Carta
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  2. 2
    Osteopontin: An Effector and an Effect of Tumor Metastasis

    Osteopontin: An Effector and an Effect of Tumor Metastasis Bằng Lalita A. Shevde, Subha Das, David W. Clark, Rajeev S. Samant

    Được phát hành 2010
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  3. 3
    Nasal Airway Obstruction: Prevalence and Anatomic Contributors

    Nasal Airway Obstruction: Prevalence and Anatomic Contributors Bằng David W. Clark, Anthony G. Del Signore, Roheen Raithatha, Brent A. Senior

    Được phát hành 2018
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    Artigo
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  4. 4
    Promoter G-quadruplex sequences are targets for base oxidation and strand cleavage during hypoxia-induced transcription

    Promoter G-quadruplex sequences are targets for base oxidation and strand cleavage during hypoxia-induced transcription Bằng David W. Clark, Tzu Phang, Michael G. Edwards, Mark W. Geraci, Mark N. Gillespie

    Được phát hành 2012
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    Artigo
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  5. 5
    Runs of homozygosity: windows into population history and trait architecture

    Runs of homozygosity: windows into population history and trait architecture Bằng Francisco C. Ceballos, Peter K. Joshi, David W. Clark, Michèle Ramsay, James F. Wilson

    Được phát hành 2018
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  6. 6
    An oxidative DNA “damage” and repair mechanism localized in the VEGF promoter is important for hypoxia-induced VEGF mRNA expression

    An oxidative DNA “damage” and repair mechanism localized in the VEGF promoter is important for hypoxia-induced VEGF mRNA expression Bằng Viktor Pastukh, Justin T. Roberts, David W. Clark, Gina C. Bardwell, Mita Patel, Abu‐Bakr Al‐Mehdi, Glen M. Borchert, Mark N. Gillespie

    Được phát hành 2015
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    Artigo
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  7. 7
    Breast cancer metastasis suppressor 1 (BRMS1) inhibits osteopontin transcription by abrogating NF-κB activation

    Breast cancer metastasis suppressor 1 (BRMS1) inhibits osteopontin transcription by abrogating NF-κB activation Bằng Rajeev S. Samant, David W. Clark, Rebecca A. Fillmore, Muzaffer Cicek, Brandon J. Metge, Kondethimmana H Chandramouli, Ann F. Chambers, Graham Casey, Danny R. Welch, Lalita A. Shevde

    Được phát hành 2007
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    Artigo
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  8. 8
    RAD6 promotes DNA repair and stem cell signaling in ovarian cancer and is a promising therapeutic target to prevent and treat acquired chemoresistance

    RAD6 promotes DNA repair and stem cell signaling in ovarian cancer and is a promising therapeutic target to prevent and treat acquired chemoresistance Bằng Ranganatha R. Somasagara, Sebastian M. Spencer, Kaushlendra Tripathi, David W. Clark, Chinnadurai Mani, Luciana Madeira da Silva, Jennifer Scalici, Hend Kothayer, Andrew D. Westwell, Rodney P. Rocconi, Komaraiah Palle

    Được phát hành 2017
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    Artigo
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  9. 9
    The genomic basis of human lifespan

    The genomic basis of human lifespan Bằng Paul R. H. J. Timmers, Ninon Mounier, Kristi Läll, Krista Fischer, Ning Zhang, Xiao Feng, Andrew D. Bretherick, David W. Clark, Xia Shen, Tõnu Esko, Zoltán Kutalik, James F. Wilson, Peter K. Joshi

    Được phát hành 2018
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    Artigo
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  10. 10
    Linking protein to phenotype with Mendelian Randomization detects 38 proteins with causal roles in human diseases and traits

    Linking protein to phenotype with Mendelian Randomization detects 38 proteins with causal roles in human diseases and traits Bằng Andrew D. Bretherick, Oriol Canela‐Xandri, Peter K. Joshi, David W. Clark, Konrad Rawlik, Thibaud Boutin, Yanni Zeng, Carmen Amador, Pau Navarro, Igor Rudan, Alan F. Wright, Harry Campbell, Véronique Vitart, Caroline Hayward, James F. Wilson, Albert Tenesa, Chris P. Ponting, J. Kenneth Baillie, Chris Haley

    Được phát hành 2020
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    Artigo
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  11. 11
    Parent of origin genetic effects on methylation in humans are common and influence complex trait variation

    Parent of origin genetic effects on methylation in humans are common and influence complex trait variation Bằng Yanni Zeng, Carmen Amador, Charley Xia, Riccardo E. Marioni, Duncan Sproul, Rosie M. Walker, Stewart W. Morris, Andrew D. Bretherick, Oriol Canela‐Xandri, Thibaud Boutin, David W. Clark, Archie Campbell, Konrad Rawlik, Caroline Hayward, Réka Nagy, Albert Tenesa, David J. Porteous, James F. Wilson, Ian J. Deary, Kathryn L. Evans, Andrew M. McIntosh, Pau Navarro, Chris Haley

    Được phát hành 2019
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    Artigo
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  12. 12
    Genome‐Wide Association Study of NAFLD Using Electronic Health Records

    Genome‐Wide Association Study of NAFLD Using Electronic Health Records Bằng Cameron J. Fairfield, Thomas M Drake, Riinu Pius, Andrew D. Bretherick, Archie Campbell, David W. Clark, Jonathan A. Fallowfield, Caroline Hayward, Neil C. Henderson, Peter K. Joshi, Nicholas L. Mills, David J. Porteous, Prakash Ramachandran, Robert K. Semple, Catherine A. Shaw, Cathie Sudlow, Paul R. H. J. Timmers, James F. Wilson, Stephen J. Wigmore, Ewen M. Harrison, Athina Spiliopoulou

    Được phát hành 2021
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  13. 13
    Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and risk of cardiovascular disease

    Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and risk of card... Bằng Andrew Crawford, Sean Bankier, Elisabeth Altmaier, Catriona L. K. Barnes, David W. Clark, Raili Ermel, Nele Friedrich, Pim van der Harst, Peter K. Joshi, Ville Karhunen, Jari Lahti, Anubha Mahajan, Massimo Mangino, Maria Nethander, Alexander Neumann, Maik Pietzner, Katyayani Sukhavasi, Carol A. Wang, Stephan J. L. Bakker, Johan Björkegren, Harry Campbell, Johan G. Eriksson, Christian Gieger, Caroline Hayward, Marjo‐Riitta Järvelin, Stela McLachlan, Andrew P. Morris, Claes Ohlsson, Craig E. Pennell, Jackie F. Price, Igor Rudan, Arno Ruusalepp, Tim D. Spector, Henning Tiemeier, Henry Völzke, James F. Wilson, Tom Michoel, Nicholas J. Timpson, George Davey Smith, Brian R. Walker, Dan Mellström

    Được phát hành 2021
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    Artigo
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  14. 14
    Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

    Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals Bằng James J. Lee, Robbee Wedow, Aysu Okbay, Edward Kong, Omeed Maghzian, Meghan Zacher, Tuan Anh Nguyen-Viet, Peter N. Bowers, Julia Sidorenko, Richard Karlsson Linnér, Mark Alan Fontana, Tushar Kundu, Chan Wook Lee, Hui Li, Ruoxi Li, Rebecca Royer, Pascal Timshel, Raymond K. Walters, Emily A. Willoughby, Loïc Yengo, Maris Alver, Yanchun Bao, David W. Clark, Felix R. Day, Nicholas A. Furlotte, Peter K. Joshi, Kathryn E. Kemper, Aaron Kleinman, Claudia Langenberg, Reedik Mägi, Joey W. Trampush, Shefali S. Verma, Yang Wu, Max Lam, Jing Hua Zhao, Zhili Zheng, Jason D. Boardman, Harry Campbell, Jeremy Freese, Kathleen Mullan Harris, Caroline Hayward, Pamela Herd, Meena Kumari, Todd Lencz, Jian’an Luan, Anil K. Malhotra, Andres Metspalu, Lili Milani, Ken K. Ong, John R. B. Perry, David J. Porteous, Marylyn D. Ritchie, Melissa Smart, Blair H. Smith, Joyce Y. Tung, Nicholas J. Wareham, James F. Wilson, Jonathan Beauchamp, Dalton Conley, Tõnu Esko, Steven F. Lehrer, Patrik K. E. Magnusson, Sven Oskarsson, Tune H. Pers, Matthew R. Robinson, Kevin Thom, Chelsea Watson, Christopher F. Chabris, Michelle N. Meyer, David Laibson, Jian Yang, Magnus Johannesson, Philipp Koellinger, Patrick Turley, Peter M. Visscher, Daniel J. Benjamin, David Cesarini

    Được phát hành 2018
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  15. 15
    Author response: Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances

    Author response: Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances Bằng Paul R. H. J. Timmers, Ninon Mounier, Kristi Läll, Krista Fischer, Ning Zheng, Xiao Feng, Andrew D. Bretherick, David W. Clark, Mawussé Agbessi, Habibul Ahsan, Isabel Alves, Anand Kumar Andiappan, Philip Awadalla, Alexis Battle, Marc Jan Bonder, Dorret I. Boomsma, Mark Christiansen, Annique Claringbould, Patrick Deelen, Jenny van Dongen, Tõnu Esko, Marie‐Julie Favé, Lude Franke, T Frayling, Sina A. Gharib, Greg Gibson, Gibran Hemani, Rick Jansen, A Kalnapenkis, Silva Kasela, Jarno L. T. Kettunen, Y Kim, Holger Kirsten, Péter Kovács, Knut Krohn, Jaanika Kronberg-Guzman, Viktorija Kukushkina, Zoltán Kutalik, Mika Kähönen, B Lee, Terho Lehtimäki, Markus Loeffler, Urko M. Marigorta, Andres Metspalu, Joyce B. J. van Meurs, Lili Milani, Martina Müller‐Nurasyid, Matthias Nauck, Michel G. Nivard, Brenda W.J.H. Penninx, Markus Perola, Natalia Pervjakova, Brandon L. Pierce, Joseph E. Powell, Holger Prokisch, BM Psaty, Olli T. Raitakari, Susan M. Ring, Samuli Ripatti, Olaf Rötzschke, Sina Rüeger, A Saha, Markus Scholz, Katharina Schramm, Ilkka Seppälä, Michael Stümvoll, Patrick Sullivan, Alexander Teumer, Joachim Thiery, Tong Lin, Anke Tönjes, Joost Verlouw, Peter M. Visscher, Urmo Võsa, Uwe Völker, Hanieh Yaghootkar, Jian Yang, Biao Zeng, F Zhang, Xia Shen, Tõnu Esko, Zoltán Kutalik, James F. Wilson, Peter K. Joshi

    Được phát hành 2018
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    Revisão por Pares
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  16. 16
    Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances

    Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances Bằng Paul R. H. J. Timmers, Ninon Mounier, Kristi Läll, Krista Fischer, Ning Zheng, Xiao Feng, Andrew D. Bretherick, David W. Clark, Mawussé Agbessi, Habibul Ahsan, Isabel Alves, Anand Kumar Andiappan, Philip Awadalla, Alexis Battle, Marc Jan Bonder, Dorret I. Boomsma, Mark Christiansen, Annique Claringbould, Patrick Deelen, Jenny van Dongen, Tõnu Esko, Marie‐Julie Favé, Lude Franke, T Frayling, Sina A. Gharib, Greg Gibson, Gibran Hemani, Rick Jansen, A Kalnapenkis, Silva Kasela, Jarno L. T. Kettunen, Y Kim, Holger Kirsten, Péter Kovács, Knut Krohn, Jaanika Kronberg-Guzman, Viktorija Kukushkina, Zoltán Kutalik, Mika Kähönen, B Lee, Terho Lehtimäki, Markus Loeffler, Urko M. Marigorta, Andres Metspalu, Joyce B. J. van Meurs, Lili Milani, Martina Müller‐Nurasyid, Matthias Nauck, Michel G. Nivard, Brenda W.J.H. Penninx, Markus Perola, Natalia Pervjakova, Brandon L. Pierce, Joseph E. Powell, Holger Prokisch, BM Psaty, Olli Raitakari, Susan M. Ring, Samuli Ripatti, Olaf Rötzschke, Sina Rüeger, A Saha, Markus Scholz, Katharina Schramm, Ilkka Seppälä, Michael Stümvoll, Patrick F. Sullivan, Alexander Teumer, Joachim Thiery, Tong Lin, Anke Tönjes, Joost Verlouw, Peter M. Visscher, Urmo Võsa, Uwe Völker, Hanieh Yaghootkar, Jian Yang, Biao Zeng, F Zhang, Mawussé Agbessi, Habibul Ahsan, Isabel Alves, Anand Kumar Andiappan, Philip Awadalla, Alexis Battle, Marc Jan Bonder, Dorret I. Boomsma, Mark Christiansen, Annique Claringbould, Patrick Deelen, Jenny van Dongen, Tõnu Esko, Marie‐Julie Favé, Lude Franke, T Frayling, Sina A. Gharib, Greg Gibson, Gibran Hemani, Rick Jansen, A Kalnapenkis

    Được phát hành 2019
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    Artigo
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  17. 17
    Longitudinal measurement and hierarchical classification framework for the prediction of Alzheimer’s disease

    Longitudinal measurement and hierarchical classification framework for the prediction of Alzheimer’s disease Bằng Meiyan Huang, Wei Yang, Qianjin Feng, Wufan Chen, Michael W. Weiner, Paul Aisen, Ronald C. Petersen, Clifford R. Jack, William J. Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, Andrew J. Saykin, John C. Morris, Leslie M. Shaw, Jeffrey Kaye, Joseph F. Quinn, Lisa C. Silbert, Betty Lind, Raina Carter, Sara Dolen, Lon S. Schneider, Sonia Pawluczyk, Mauricio Beccera, Liberty Teodoro, Bryan M. Spann, James Brewer, Helen Vanderswag, Adam Fleisher, Judith L. Heidebrink, Joanne Lord, Sara S. Mason, Colleen S. Albers, David S. Knopman, Kris Johnson, Rachelle S. Doody, Javier Villanueva‐Meyer, Munir Chowdhury, Susan Rountree, Mimi Dang, Yaakov Stern, Lawrence S. Honig, Karen L. Bell, Beau M. Ances, John C. Morris, Maria Carroll, Mary L. Creech, Erin Franklin, Mark A. Mintun, Stacy Schneider, Angela Oliver, Daniel Marson, Randall Griffith, David W. Clark, David Geldmacher, John Brockington, Erik D. Roberson, Marissa Natelson Love, Hillel Grossman, Effie Mitsis, Raj C. Shah, Leyla deToledo‐Morrell, Ranjan Duara, Daniel Varon, Maria T. Greig, Peggy Roberts, Marilyn Albert, Chiadi U. Onyike, Daniel D’Agostino, Stephanie Kielb, James E. Galvin, Brittany Cerbone, Christina A. Michel, Dana M. Pogorelec, Henry Rusinek, Mony J. de Leon, Lidia Glodzik, Susan De Santi, P. Murali Doraiswamy, Jeffrey R. Petrella, Salvador Borges‐Neto, Terence Z. Wong, Edward Coleman, Charles D. Smith, Gregory A. Jicha, Peter Hardy, Partha Sinha, Elizabeth Oates, Gary Conrad, Anton P. Porsteinsson, Bonnie S. Goldstein, Kim Martin, Kelly M. Makino, M. Saleem Ismail, Connie Brand, Ruth A. Mulnard, Gaby Thai, Catherine Mc-Adams-Ortiz, Kyle Womack

    Được phát hành 2017
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    Artigo
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  18. 18
    Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

    Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences Bằng Richard Karlsson Linnér, Pietro Biroli, Edward Kong, S. Fleur W. Meddens, Robbee Wedow, Mark Alan Fontana, Maël P. Lebreton, Stephen P. Tino, Abdel Abdellaoui, Anke R. Hammerschlag, Michel G. Nivard, Aysu Okbay, Cornelius A. Rietveld, Pascal Timshel, Maciej Trzaskowski, Ronald de Vlaming, Christian Zünd, Yanchun Bao, Laura Buzdugan, Ann H. Caplin, Chia‐Yen Chen, Peter Eibich, Pierre Fontanillas, Juan R. González, Peter K. Joshi, Ville Karhunen, Aaron Kleinman, Remy Z. Levin, Christina M. Lill, Gerardus A. Meddens, Gerard Muntané, Sandra Sanchez‐Roige, Frank J.A. van Rooij, Erdogan Taskesen, Yang Wu, Futao Zhang, Adam Auton, Jason D. Boardman, David W. Clark, Andrew Conlin, Conor Dolan, Urs Fischbacher, Patrick J. F. Groenen, Kathleen Mullan Harris, Gregor Hasler, Albert Hofman, M. Arfan Ikram, Sonia Jain, Robert Karlsson, Ronald C. Kessler, Maarten Kooyman, James MacKillop, Minna Männikkö, Carlos Morcillo-Suárez, Matthew B. McQueen, Klaus M. Schmidt, Melissa Smart, Matthias Sutter, Roy Thurik, André G. Uitterlinden, Jon White, Harriet de Wit, Jian Yang, Lars Bertram, Dorret I. Boomsma, Tõnu Esko, Ernst Fehr, David A. Hinds, Magnus Johannesson, Meena Kumari, David Laibson, Patrik K. E. Magnusson, Michelle N. Meyer, Arcadi Navarro, Abraham A. Palmer, Tune H. Pers, Daniëlle Posthuma, Daniel Schunk, Murray B. Stein, Rauli Svento, Henning Tiemeier, Paul R. H. J. Timmers, Patrick Turley, Robert J. Ursano, Gert G. Wagner, James F. Wilson, Jacob Gratten, James J. Lee, David Cesarini, Daniel J. Benjamin, Philipp Koellinger, Jonathan Beauchamp

    Được phát hành 2019
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  19. 19
    Multimodal Hippocampal Subfield Grading For Alzheimer’s Disease Classification

    Multimodal Hippocampal Subfield Grading For Alzheimer’s Disease Classification Bằng Kilian Hett, Vinh‐Thong Ta, Gwénaëlle Catheline, Thomas Tourdias, José V. Manjón, Pierrick Coupé, Michael W. Weiner, Paul Aisen, Ronald Petersen, Clifford R. Jack, William J. Jagust, John Q. Trojanowki, Arthur W. Toga, Laurel Beckett, Robert C. Green, Andrew J. Saykin, John C. Morris, Leslie M. Shaw, Zaven S. Khachaturian, Greg Sorensen, Marı́a C. Carrillo, Lew Kuller, Marc Raichle, Steven M. Paul, Peter J. Davies, Howard Fillit, Franz Hefti, Davie Holtzman, M. Marcel Mesulam, William C. Potter, Peter J. Snyder, Tom Montine, Ronald G. Thomas, Michael Donohue, Sarah Walter, Tamie Sather, Gus Jiminez, Archana B. Balasubramanian, Jennifer Mason, Iris Sim, Danielle Harvey, Matt A. Bernstein, Nick C. Fox, Paul Thompson, Norbert Schuff, Charles DeCarli, Bret Borowski, Jeff Gunter, Matthew L. Senjem, Prashanthi Vemuri, David T. Jones, Kejal Kantarci, Chad Ward, Robert A. Koeppe, Norm Foster, Eric M. Reiman, Kewei Chen, Chester A. Mathis, Susan Landau, Nigel J. Cairns, Erin Householder, Lisa Taylor‐Reinwald, Virginia Lee, Magdalena Korecka, Michal Figurski, Karen Crawford, Scott Neu, Tatiana M. Foroud, Steven Potkin, Li Shen, Kelley Faber, Sungeun Kim, Kwangsik Nho, Lean Thal, R.T. Frank, John Hsiao, Jeffrey Kaye, Joseph F. Quinn, Lisa C. Silbert, Betty Lind, Raina Carter, Sara Dolen, Beau M. Ances, Maria Carroll, Mary L. Creech, Erin Franklin, Mark A. Mintun, Stacy Schneider, Angela Oliver, Lon S. Schneider, Sonia Pawluczyk, Mauricio Beccera, Liberty Teodoro, Bryan M. Spann, James Brewer, Helen Vanderswag, Adam Fleisher, Daniel Marson, Randall Griffith, David W. Clark

    Được phát hành 2019
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    Artigo
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  20. 20
    Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences<sup>1</sup>

    Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences<sup>1</sup> Bằng Richard Karlsson Linnér, Pietro Biroli, Edward Kong, S. Fleur W. Meddens, Robbee Wedow, Mark Alan Fontana, Maël P. Lebreton, Abdel Abdellaoui, Anke R. Hammerschlag, Michel G. Nivard, Aysu Okbay, Cornelius A. Rietveld, Pascal Timshel, Stephen P. Tino, Maciej Trzaskowski, Ronald de Vlaming, Christian Zünd, Yanchun Bao, Laura Buzdugan, Ann H. Caplin, Chia‐Yen Chen, Peter Eibich, Pierre Fontanillas, Juan R Gonzalez, Peter K. Joshi, Ville Karhunen, Aaron Kleinman, Remy Z. Levin, Christina M. Lill, Gerardus A. Meddens, Gerard Muntané, Sandra Sanchez‐Roige, Frank J.A. van Rooij, Erdogan Taskesen, Yang Wu, Futao Zhang, Adam Auton, Jason D. Boardman, David W. Clark, Andrew Conlin, Conor Dolan, Urs Fischbacher, Patrick J. F. Groenen, Kathleen Mullan Harris, Gregor Hasler, Albert Hofman, M. Arfan Ikram, Sonia Jain, Robert Karlsson, Ronald C. Kessler, Maarten Kooyman, James MacKillop, Minna Männikkö, Carlos Morcillo-Suárez, Matthew B. McQueen, Klaus M. Schmidt, Melissa Smart, Matthias Sutter, Roy Thurik, André G. Uitterlinden, Jon White, Harriet de Wit, Jian Yang, Lars Bertram, Dorret I. Boomsma, Tõnu Esko, Ernst Fehr, David A. Hinds, Magnus Johannesson, Meena Kumari, David Laibson, Patrik K. E. Magnusson, Michelle N. Meyer, Arcadi Navarro, Abraham A. Palmer, Tune H. Pers, Daniëlle Posthuma, Daniel Schunk, Murray B. Stein, Rauli Svento, Henning Tiemeier, Paul R. H. J. Timmers, Patrick Turley, Robert J. Ursano, Gert G. Wagner, James F. Wilson, Jacob Gratten, James J. Lee, David Cesarini, Daniel J. Benjamin, Philipp Koellinger, Jonathan Beauchamp

    Được phát hành 2018
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