Søgeresultater - David U. Gorkin

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  1. 1
    The 3D Genome in Transcriptional Regulation and Pluripotency

    The 3D Genome in Transcriptional Regulation and Pluripotency af David U. Gorkin, Danny Leung, Bing Ren

    Udgivet 2014
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  2. 2
    Chromatin Domains: The Unit of Chromosome Organization

    Chromatin Domains: The Unit of Chromosome Organization af Jesse R. Dixon, David U. Gorkin, Bing Ren

    Udgivet 2016
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  3. 3
    Removing unwanted variation between samples in Hi-C experiments

    Removing unwanted variation between samples in Hi-C experiments af Kipper Fletez‐Brant, Yunjiang Qiu, David U. Gorkin, Ming Hu, Kasper D. Hansen

    Udgivet 2024
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  4. 4
    A method to predict the impact of regulatory variants from DNA sequence

    A method to predict the impact of regulatory variants from DNA sequence af Dongwon Lee, David U. Gorkin, Maggie Baker, Benjamin J. Strober, Alessandro L Asoni, Andrew S. McCallion, M Beer

    Udgivet 2015
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  5. 5
    Integration of ChIP-seq and machine learning reveals enhancers and a predictive regulatory sequence vocabulary in melanocytes

    Integration of ChIP-seq and machine learning reveals enhancers and a predictive regulatory sequence vocabulary in melanocytes af David U. Gorkin, Dongwon Lee, Xylena Reed, Christopher Fletez-Brant, Seneca L. Bessling, Stacie K. Loftus, M Beer, William J. Pavan, Andrew S. McCallion

    Udgivet 2012
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  6. 6
    Improved regulatory element prediction based on tissue-specific local epigenomic signatures

    Improved regulatory element prediction based on tissue-specific local epigenomic signatures af Yupeng He, David U. Gorkin, Diane E. Dickel, Joseph R. Nery, Rosa Castanon, Ah Young Lee, Yin Shen, Axel Visel, L Pennacchio, Bing Ren, Joseph R. Ecker

    Udgivet 2017
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  7. 7
    Preservation of Chromatin Organization after Acute Loss of CTCF in Mouse Embryonic Stem Cells

    Preservation of Chromatin Organization after Acute Loss of CTCF in Mouse Embryonic Stem Cells af Naoki Kubo, Haruhiko Ishii, David U. Gorkin, Franz Meitinger, Xiong Xiong, Rongxin Fang, Tristin Liu, Zhen Ye, Bin Li, Jesse R. Dixon, Arshad Desai, Huimin Zhao, Bing Ren

    Udgivet 2017
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  8. 8
    Mapping genetic effects on cell type-specific chromatin accessibility and annotating complex immune trait variants using single nucleus ATAC-seq in peripheral blood

    Mapping genetic effects on cell type-specific chromatin accessibility and annotating complex immune trait variants using single nucleus ATAC-seq in peripheral blood af Paola Benaglio, Jacklyn Newsome, Jee Yun Han, Joshua Chiou, Anthony Aylward, Sierra Corban, Michael Miller, Mei-Lin Okino, Jaspreet Kaur, Sebastian Preißl, David U. Gorkin, Kyle J. Gaulton

    Udgivet 2023
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  9. 9
    Common DNA sequence variation influences 3-dimensional conformation of the human genome

    Common DNA sequence variation influences 3-dimensional conformation of the human genome af David U. Gorkin, Yunjiang Qiu, Ming Hu, Kipper Fletez‐Brant, Tristin Liu, Anthony D. Schmitt, Amina Noor, Joshua Chiou, Kyle J. Gaulton, Jonathan Sebat, Yun Li, Kasper D. Hansen, Bing Ren

    Udgivet 2019
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  10. 10
    Single-nucleus analysis of accessible chromatin in developing mouse forebrain reveals cell-type-specific transcriptional regulation

    Single-nucleus analysis of accessible chromatin in developing mouse forebrain reveals cell-type-specific transcriptional regulation af Sebastian Preißl, Rongxin Fang, Hui Huang, Yuan Zhao, Ramya Raviram, David U. Gorkin, Yanxiao Zhang, Brandon C. Sos, Veena Afzal, Diane E. Dickel, Samantha Kuan, Axel Visel, L Pennacchio, Kun Zhang, Bing Ren

    Udgivet 2018
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  11. 11
    Promoter-proximal CTCF binding promotes distal enhancer-dependent gene activation

    Promoter-proximal CTCF binding promotes distal enhancer-dependent gene activation af Naoki Kubo, Haruhiko Ishii, Xiong Xiong, Simona Bianco, Franz Meitinger, Rong Hu, James D. Hocker, Mattia Conte, David U. Gorkin, Miao Yu, Bin Li, Jesse R. Dixon, Ming Hu, Mario Nicodemi, Huimin Zhao, Bing Ren

    Udgivet 2021
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  12. 12
    Interpreting type 1 diabetes risk with genetics and single-cell epigenomics

    Interpreting type 1 diabetes risk with genetics and single-cell epigenomics af Joshua Chiou, Ryan J. Geusz, Mei-Lin Okino, Jee Yun Han, Michael Miller, Rebecca Melton, Elisha Beebe, Paola Benaglio, Serina Huang, Katha Korgaonkar, Sandra Heller, Alexander Kleger, Sebastian Preißl, David U. Gorkin, Maike Sander, Kyle J. Gaulton

    Udgivet 2021
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  13. 13
    Generation and Characterization of a Knockout Mouse of an Enhancer of<i>EBF3</i>

    Generation and Characterization of a Knockout Mouse of an Enhancer of<i>EBF3</i> af Emily Cordova Hurtado, Janine M. Wotton, Alexander O. D. Gulka, Crystal Burke, Jeffrey K. Ng, Ibrahim Bah, Juana G. Manuel, Hillary B. Heins, Stephen A. Murray, David U. Gorkin, Jacqueline K. White, Kevin A. Peterson, Tychele N. Turner

    Udgivet 2025
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  14. 14
    SOX10 directly modulates ERBB3 transcription via an intronic neural crest enhancer

    SOX10 directly modulates ERBB3 transcription via an intronic neural crest enhancer af Megana Prasad, Xylena Reed, David U. Gorkin, Julia C. Cronin, Anthony R. McAdow, Kristopher H. Chain, Chani J. Hodonsky, Erin A. Jones, John Svaren, Anthony Antonellis, Stephen L. Johnson, Stacie K. Loftus, William J. Pavan, Andrew S. McCallion

    Udgivet 2011
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  15. 15
    CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function

    CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function af Ya Guo, Quan Xu, Daniele Canzio, Jia Shou, Jinhuan Li, David U. Gorkin, Inkyung Jung, Haiyang Wu, Yanan Zhai, Yuanxiao Tang, Yichao Lu, Yonghu Wu, Zhilian Jia, Wei Li, Michael Q. Zhang, Bing Ren, Adrian R. Krainer, Tom Maniatis, Qiang Wu

    Udgivet 2015
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  16. 16
    Knock in of the AKT1 E17K mutation in human breast epithelial cells does not recapitulate oncogenic PIK3CA mutations

    Knock in of the AKT1 E17K mutation in human breast epithelial cells does not recapitulate oncogenic PIK3CA mutations af Josh Lauring, David Cosgrove, Stefani C. Fontana, John P. Gustin, Hiroyuki Konishi, Abde M. Abukhdeir, Joseph P. Garay, Morassa Mohseni, Guoli Wang, Michaela J. Higgins, David U. Gorkin, Marcelo Reis, Bert Vogelstein, Kornélia Polyák, Marianne Cowherd, Phillip Buckhaults, B H Park

    Udgivet 2010
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  17. 17
    Single-cell chromatin accessibility identifies pancreatic islet cell type– and state-specific regulatory programs of diabetes risk

    Single-cell chromatin accessibility identifies pancreatic islet cell type– and state-specific regulatory programs of diabetes risk af Joshua Chiou, Chun Zeng, Cheng Zhang, Jee Yun Han, Michael Schlichting, Michael Miller, Robert Mendez, Serina Huang, Jinzhao Wang, Yinghui Sui, Allison Deogaygay, Mei-Lin Okino, Yunjiang Qiu, Ying Sun, Parul Kudtarkar, Rongxin Fang, Sebastian Preißl, Maike Sander, David U. Gorkin, Kyle J. Gaulton

    Udgivet 2021
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  18. 18
    Spatiotemporal DNA methylome dynamics of the developing mouse fetus

    Spatiotemporal DNA methylome dynamics of the developing mouse fetus af Yupeng He, Manoj Hariharan, David U. Gorkin, Diane E. Dickel, Chongyuan Luo, Rosa Castanon, Joseph R. Nery, Ah Young Lee, Yuan Zhao, Hui Huang, Brian A. Williams, Diane Trout, Henry Amrhein, Rongxin Fang, Huaming Chen, Bin Li, Axel Visel, L Pennacchio, Bing Ren, Joseph R. Ecker

    Udgivet 2020
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  19. 19
    Genome-wide compendium and functional assessment of in vivo heart enhancers

    Genome-wide compendium and functional assessment of in vivo heart enhancers af Diane E. Dickel, Iros Barozzi, Yiwen Zhu, Y. Fukuda, Marco Osterwalder, Brandon J. Mannion, Dalit May, Cailyn H. Spurrell, Ingrid Plajzer-Frick, Catherine S. Pickle, Elizabeth Lee, Tyler H. Garvin, Momoe Kato, Jennifer A. Akiyama, Veena Afzal, Ah Young Lee, David U. Gorkin, Bing Ren, Edward M. Rubin, Axel Visel, L Pennacchio

    Udgivet 2016
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  20. 20
    Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk

    Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk af William W. Greenwald, Joshua Chiou, Jian Yan, Yunjiang Qiu, Ning Dai, Allen Wang, Naoki Nariai, Anthony Aylward, Jee Yun Han, Nikita Kadakia, Laura Regué, Mei-Lin Okino, Frauke Drees, Dana Krämer, Nicholas K. Vinckier, Liliana Minichiello, David U. Gorkin, Joseph Avruch, Kelly A. Frazer, Maike Sander, Bing Ren, Kyle J. Gaulton

    Udgivet 2019
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