Rezultati pretrage autora

1

Enhanced Sensitivity of G1 Arrested Human Cancer Cells Suggests a Novel Therapeutic Strategy Using a Combination of Simvastatin and TRAIL od Zhaoyu Jin, David T. Dicker, Wafik S. El‐Deiry

Izdano 2002

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2

Small-Molecule ONC201/TIC10 Targets Chemotherapy-Resistant Colorectal Cancer Stem–like Cells in an Akt/Foxo3a/TRAIL–Dependent Manner od Varun V. Prabhu, Joshua E. Allen, David T. Dicker, Wafik S. El‐Deiry

Izdano 2015

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3

Deficient Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Death Receptor Transport to the Cell Surface in Human Colon Cancer Cells Selected for Resistance to TRAIL-... od Zhaoyu Jin, E. Robert McDonald, David T. Dicker, Wafik S. El‐Deiry

Izdano 2004

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4

The CDK4/6 inhibitor palbociclib synergizes with irinotecan to promote colorectal cancer cell death under hypoxia od Jun Zhang, Lanlan Zhou, Shuai Zhao, David T. Dicker, Wafik S. El‐Deiry

Izdano 2017

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5

Circulating tumor cells: silent predictors of metastasis od Lanlan Zhou, David T. Dicker, Elizabeth Matthew, Wafik S. El‐Deiry, R. Katherine Alpaugh

Izdano 2017

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6

CDK1 stabilizes HIF-1α via direct phosphorylation of Ser668 to promote tumor growth od Noel A. Warfel, Nathan G. Dolloff, David T. Dicker, Jozef Malysz, Wafik S. El‐Deiry

Izdano 2013

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7

Silencing of the Novel p53 Target Gene Snk/Plk2 Leads to Mitotic Catastrophe in Paclitaxel (Taxol)-Exposed Cells od Timothy F. Burns, Peiwen Fei, Kimberly A. Scata, David T. Dicker, Wafik S. El‐Deiry

Izdano 2003

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8

The Mutant p53-Conformation Modifying Drug, CP-31398, Can Induce Apoptosis od Rishu Takimoto, Wenge Wang, David T. Dicker, Farzan Rastinejad, Joseph P. Lyssikatos, Wafik S. El‐Deiry

Izdano 2002

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9

BRCA1 Transcriptionally Regulates Damaged DNA Binding Protein (DDB2) In the DNA Repair Response Following UV-Irradiation od Rishu Takimoto, Timothy K. MacLachlan, David T. Dicker, Yoshiro Niitsu, Toshio Mori, Wafik S. El‐Deiry

Izdano 2002

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10

Direct Repression of FLIP Expression by c-myc Is a Major Determinant of TRAIL Sensitivity od M. Ricci, Zhaoyu Jin, Michael Dews, Duonan Yu, Andrei Thomas‐Tikhonenko, David T. Dicker, Wafik S. El‐Deiry

Izdano 2004

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11

Human colon cancer stem cells are enriched by insulin-like growth factor-1 and are sensitive to figitumumab od Lori S. Hart, Nathan G. Dolloff, David T. Dicker, Constantinos Koumenis, James G. Christensen, Adda Grimberg, Wafik S. El‐Deiry

Izdano 2011

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12

miR-6883 Family miRNAs Target CDK4/6 to Induce G1 Phase Cell-Cycle Arrest in Colon Cancer Cells od Amriti R. Lulla, Michael Slifker, Yan Zhou, Avital Lev, Margret B. Einarson, David T. Dicker, Wafik S. El‐Deiry

Izdano 2017

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13

Identification and enumeration of circulating tumor cells in the cerebrospinal fluid of breast cancer patients with central nervous system metastases od Akshal Patel, Joshua E. Allen, David T. Dicker, Kristi L. Peters, Jonas M. Sheehan, Michael Glantz, Wafik S. El‐Deiry

Izdano 2011

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14

Identification of TRAIL-inducing compounds highlights small molecule ONC201/TIC10 as a unique anti-cancer agent that activates the TRAIL pathway od Joshua E. Allen, Gabriel Krigsfeld, Luv Patel, Patrick A. Mayes, David T. Dicker, Gen Sheng Wu, Wafik S. El‐Deiry

Izdano 2015

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15

Small-Molecule Prodigiosin Restores p53 Tumor Suppressor Activity in Chemoresistant Colorectal Cancer Stem Cells via c-Jun-Mediated ΔNp73 Inhibition and p73 Activation od Varun V. Prabhu, Bo Hong, Joshua E. Allen, Shengliang Zhang, Amriti R. Lulla, David T. Dicker, Wafik S. El‐Deiry

Izdano 2016

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16

TNFSF10 (TRAIL), a p53 target gene that mediates p53-dependent cell death od Kageaki Kuribayashi, Gabriel Krigsfeld, Wenge Wang, Jing Xu, Patrick A. Mayes, David T. Dicker, Gen Sheng Wu, Wafik S. El‐Deiry

Izdano 2008

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17

The p53 target Plk2 interacts with TSC proteins impacting mTOR signaling, tumor growth, and chemosensitivity under hypoxic conditions od Elizabeth Matthew, Lori S. Hart, Aristotelis Astrinidis, Arunasalam Navaraj, Nathan G. Dolloff, David T. Dicker, Elizabeth P. Henske, Wafik S. El‐Deiry

Izdano 2009

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18

Death Induction by Recombinant Native TRAIL and Its Prevention by a Caspase 9 Inhibitor in Primary Human Esophageal Epithelial Cells od Seok‐Hyun Kim, Kunhong Kim, Jae Kwagh, David T. Dicker, Meenhard Herlyn, Anil K. Rustgi, Youhai Chen, Wafik S. El‐Deiry

Izdano 2004

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19

Prodigiosin Rescues Deficient p53 Signaling and Antitumor Effects via Upregulating p73 and Disrupting Its Interaction with Mutant p53 od Bo Hong, Varun V. Prabhu, Shengliang Zhang, A. Pieter J. van den Heuvel, David T. Dicker, Levy Kopelovich, Wafik S. El‐Deiry

Izdano 2013

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20

Sorafenib Sensitizes Solid Tumors to Apo2L/TRAIL and Apo2L/TRAIL Receptor Agonist Antibodies by the Jak2-Stat3-Mcl1 Axis od Junaid Abdulghani, Joshua E. Allen, David T. Dicker, Yingqiu Yvette Liu, David Goldenberg, Charles D. Smith, Robin Humphreys, Wafik S. El‐Deiry

Izdano 2013

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Enhanced Sensitivity of G1 Arrested Human Cancer Cells Suggests a Novel Therapeutic Strategy Using a Combination of Simvastatin and TRAIL od Zhaoyu Jin, David T. Dicker, Wafik S. El‐Deiry

Small-Molecule ONC201/TIC10 Targets Chemotherapy-Resistant Colorectal Cancer Stem–like Cells in an Akt/Foxo3a/TRAIL–Dependent Manner od Varun V. Prabhu, Joshua E. Allen, David T. Dicker, Wafik S. El‐Deiry

Deficient Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Death Receptor Transport to the Cell Surface in Human Colon Cancer Cells Selected for Resistance to TRAIL-... od Zhaoyu Jin, E. Robert McDonald, David T. Dicker, Wafik S. El‐Deiry

The CDK4/6 inhibitor palbociclib synergizes with irinotecan to promote colorectal cancer cell death under hypoxia od Jun Zhang, Lanlan Zhou, Shuai Zhao, David T. Dicker, Wafik S. El‐Deiry

Circulating tumor cells: silent predictors of metastasis od Lanlan Zhou, David T. Dicker, Elizabeth Matthew, Wafik S. El‐Deiry, R. Katherine Alpaugh

CDK1 stabilizes HIF-1α via direct phosphorylation of Ser668 to promote tumor growth od Noel A. Warfel, Nathan G. Dolloff, David T. Dicker, Jozef Malysz, Wafik S. El‐Deiry

Silencing of the Novel p53 Target Gene <i>Snk</i>/<i>Plk2</i> Leads to Mitotic Catastrophe in Paclitaxel (Taxol)-Exposed Cells od Timothy F. Burns, Peiwen Fei, Kimberly A. Scata, David T. Dicker, Wafik S. El‐Deiry

The Mutant p53-Conformation Modifying Drug, CP-31398, Can Induce Apoptosis od Rishu Takimoto, Wenge Wang, David T. Dicker, Farzan Rastinejad, Joseph P. Lyssikatos, Wafik S. El‐Deiry

BRCA1 Transcriptionally Regulates Damaged DNA Binding Protein (DDB2) In the DNA Repair Response Following UV-Irradiation od Rishu Takimoto, Timothy K. MacLachlan, David T. Dicker, Yoshiro Niitsu, Toshio Mori, Wafik S. El‐Deiry

Direct Repression of <i>FLIP</i> Expression by c-myc Is a Major Determinant of TRAIL Sensitivity od M. Ricci, Zhaoyu Jin, Michael Dews, Duonan Yu, Andrei Thomas‐Tikhonenko, David T. Dicker, Wafik S. El‐Deiry

Human colon cancer stem cells are enriched by insulin-like growth factor-1 and are sensitive to figitumumab od Lori S. Hart, Nathan G. Dolloff, David T. Dicker, Constantinos Koumenis, James G. Christensen, Adda Grimberg, Wafik S. El‐Deiry

miR-6883 Family miRNAs Target CDK4/6 to Induce G1 Phase Cell-Cycle Arrest in Colon Cancer Cells od Amriti R. Lulla, Michael Slifker, Yan Zhou, Avital Lev, Margret B. Einarson, David T. Dicker, Wafik S. El‐Deiry

Identification and enumeration of circulating tumor cells in the cerebrospinal fluid of breast cancer patients with central nervous system metastases od Akshal Patel, Joshua E. Allen, David T. Dicker, Kristi L. Peters, Jonas M. Sheehan, Michael Glantz, Wafik S. El‐Deiry

Identification of TRAIL-inducing compounds highlights small molecule ONC201/TIC10 as a unique anti-cancer agent that activates the TRAIL pathway od Joshua E. Allen, Gabriel Krigsfeld, Luv Patel, Patrick A. Mayes, David T. Dicker, Gen Sheng Wu, Wafik S. El‐Deiry

Small-Molecule Prodigiosin Restores p53 Tumor Suppressor Activity in Chemoresistant Colorectal Cancer Stem Cells via c-Jun-Mediated ΔNp73 Inhibition and p73 Activation od Varun V. Prabhu, Bo Hong, Joshua E. Allen, Shengliang Zhang, Amriti R. Lulla, David T. Dicker, Wafik S. El‐Deiry

TNFSF10 (TRAIL), a p53 target gene that mediates p53-dependent cell death od Kageaki Kuribayashi, Gabriel Krigsfeld, Wenge Wang, Jing Xu, Patrick A. Mayes, David T. Dicker, Gen Sheng Wu, Wafik S. El‐Deiry

The p53 target Plk2 interacts with TSC proteins impacting mTOR signaling, tumor growth, and chemosensitivity under hypoxic conditions od Elizabeth Matthew, Lori S. Hart, Aristotelis Astrinidis, Arunasalam Navaraj, Nathan G. Dolloff, David T. Dicker, Elizabeth P. Henske, Wafik S. El‐Deiry

Death Induction by Recombinant Native TRAIL and Its Prevention by a Caspase 9 Inhibitor in Primary Human Esophageal Epithelial Cells od Seok‐Hyun Kim, Kunhong Kim, Jae Kwagh, David T. Dicker, Meenhard Herlyn, Anil K. Rustgi, Youhai Chen, Wafik S. El‐Deiry

Prodigiosin Rescues Deficient p53 Signaling and Antitumor Effects via Upregulating p73 and Disrupting Its Interaction with Mutant p53 od Bo Hong, Varun V. Prabhu, Shengliang Zhang, A. Pieter J. van den Heuvel, David T. Dicker, Levy Kopelovich, Wafik S. El‐Deiry

Sorafenib Sensitizes Solid Tumors to Apo2L/TRAIL and Apo2L/TRAIL Receptor Agonist Antibodies by the Jak2-Stat3-Mcl1 Axis od Junaid Abdulghani, Joshua E. Allen, David T. Dicker, Yingqiu Yvette Liu, David Goldenberg, Charles D. Smith, Robin Humphreys, Wafik S. El‐Deiry

Rezultati pretrage - David T. Dicker

Enhanced Sensitivity of G1 Arrested Human Cancer Cells Suggests a Novel Therapeutic Strategy Using a Combination of Simvastatin and TRAIL od Zhaoyu Jin, David T. Dicker, Wafik S. El‐Deiry

Small-Molecule ONC201/TIC10 Targets Chemotherapy-Resistant Colorectal Cancer Stem–like Cells in an Akt/Foxo3a/TRAIL–Dependent Manner od Varun V. Prabhu, Joshua E. Allen, David T. Dicker, Wafik S. El‐Deiry

Deficient Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Death Receptor Transport to the Cell Surface in Human Colon Cancer Cells Selected for Resistance to TRAIL-... od Zhaoyu Jin, E. Robert McDonald, David T. Dicker, Wafik S. El‐Deiry

The CDK4/6 inhibitor palbociclib synergizes with irinotecan to promote colorectal cancer cell death under hypoxia od Jun Zhang, Lanlan Zhou, Shuai Zhao, David T. Dicker, Wafik S. El‐Deiry

Circulating tumor cells: silent predictors of metastasis od Lanlan Zhou, David T. Dicker, Elizabeth Matthew, Wafik S. El‐Deiry, R. Katherine Alpaugh

CDK1 stabilizes HIF-1α via direct phosphorylation of Ser668 to promote tumor growth od Noel A. Warfel, Nathan G. Dolloff, David T. Dicker, Jozef Malysz, Wafik S. El‐Deiry

Silencing of the Novel p53 Target Gene <i>Snk</i>/<i>Plk2</i> Leads to Mitotic Catastrophe in Paclitaxel (Taxol)-Exposed Cells od Timothy F. Burns, Peiwen Fei, Kimberly A. Scata, David T. Dicker, Wafik S. El‐Deiry

The Mutant p53-Conformation Modifying Drug, CP-31398, Can Induce Apoptosis od Rishu Takimoto, Wenge Wang, David T. Dicker, Farzan Rastinejad, Joseph P. Lyssikatos, Wafik S. El‐Deiry

BRCA1 Transcriptionally Regulates Damaged DNA Binding Protein (DDB2) In the DNA Repair Response Following UV-Irradiation od Rishu Takimoto, Timothy K. MacLachlan, David T. Dicker, Yoshiro Niitsu, Toshio Mori, Wafik S. El‐Deiry

Direct Repression of <i>FLIP</i> Expression by c-myc Is a Major Determinant of TRAIL Sensitivity od M. Ricci, Zhaoyu Jin, Michael Dews, Duonan Yu, Andrei Thomas‐Tikhonenko, David T. Dicker, Wafik S. El‐Deiry

Human colon cancer stem cells are enriched by insulin-like growth factor-1 and are sensitive to figitumumab od Lori S. Hart, Nathan G. Dolloff, David T. Dicker, Constantinos Koumenis, James G. Christensen, Adda Grimberg, Wafik S. El‐Deiry

miR-6883 Family miRNAs Target CDK4/6 to Induce G1 Phase Cell-Cycle Arrest in Colon Cancer Cells od Amriti R. Lulla, Michael Slifker, Yan Zhou, Avital Lev, Margret B. Einarson, David T. Dicker, Wafik S. El‐Deiry

Identification and enumeration of circulating tumor cells in the cerebrospinal fluid of breast cancer patients with central nervous system metastases od Akshal Patel, Joshua E. Allen, David T. Dicker, Kristi L. Peters, Jonas M. Sheehan, Michael Glantz, Wafik S. El‐Deiry

Identification of TRAIL-inducing compounds highlights small molecule ONC201/TIC10 as a unique anti-cancer agent that activates the TRAIL pathway od Joshua E. Allen, Gabriel Krigsfeld, Luv Patel, Patrick A. Mayes, David T. Dicker, Gen Sheng Wu, Wafik S. El‐Deiry

Small-Molecule Prodigiosin Restores p53 Tumor Suppressor Activity in Chemoresistant Colorectal Cancer Stem Cells via c-Jun-Mediated ΔNp73 Inhibition and p73 Activation od Varun V. Prabhu, Bo Hong, Joshua E. Allen, Shengliang Zhang, Amriti R. Lulla, David T. Dicker, Wafik S. El‐Deiry

TNFSF10 (TRAIL), a p53 target gene that mediates p53-dependent cell death od Kageaki Kuribayashi, Gabriel Krigsfeld, Wenge Wang, Jing Xu, Patrick A. Mayes, David T. Dicker, Gen Sheng Wu, Wafik S. El‐Deiry

The p53 target Plk2 interacts with TSC proteins impacting mTOR signaling, tumor growth, and chemosensitivity under hypoxic conditions od Elizabeth Matthew, Lori S. Hart, Aristotelis Astrinidis, Arunasalam Navaraj, Nathan G. Dolloff, David T. Dicker, Elizabeth P. Henske, Wafik S. El‐Deiry

Death Induction by Recombinant Native TRAIL and Its Prevention by a Caspase 9 Inhibitor in Primary Human Esophageal Epithelial Cells od Seok‐Hyun Kim, Kunhong Kim, Jae Kwagh, David T. Dicker, Meenhard Herlyn, Anil K. Rustgi, Youhai Chen, Wafik S. El‐Deiry

Prodigiosin Rescues Deficient p53 Signaling and Antitumor Effects via Upregulating p73 and Disrupting Its Interaction with Mutant p53 od Bo Hong, Varun V. Prabhu, Shengliang Zhang, A. Pieter J. van den Heuvel, David T. Dicker, Levy Kopelovich, Wafik S. El‐Deiry

Sorafenib Sensitizes Solid Tumors to Apo2L/TRAIL and Apo2L/TRAIL Receptor Agonist Antibodies by the Jak2-Stat3-Mcl1 Axis od Junaid Abdulghani, Joshua E. Allen, David T. Dicker, Yingqiu Yvette Liu, David Goldenberg, Charles D. Smith, Robin Humphreys, Wafik S. El‐Deiry

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