Torthaí cuardaigh - David T. Dicker

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  1. 1
    Enhanced Sensitivity of G1 Arrested Human Cancer Cells Suggests a Novel Therapeutic Strategy Using a Combination of Simvastatin and TRAIL

    Enhanced Sensitivity of G1 Arrested Human Cancer Cells Suggests a Novel Therapeutic Strategy Using a Combination of Simvastatin and TRAIL de réir Zhaoyu Jin, David T. Dicker, Wafik S. El‐Deiry

    Foilsithe / Cruthaithe 2002
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  2. 2
    Small-Molecule ONC201/TIC10 Targets Chemotherapy-Resistant Colorectal Cancer Stem–like Cells in an Akt/Foxo3a/TRAIL–Dependent Manner

    Small-Molecule ONC201/TIC10 Targets Chemotherapy-Resistant Colorectal Cancer Stem–like Cells in an Akt/Foxo3a/TRAIL–Dependent Manner de réir Varun V. Prabhu, Joshua E. Allen, David T. Dicker, Wafik S. El‐Deiry

    Foilsithe / Cruthaithe 2015
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  3. 3
    Deficient Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Death Receptor Transport to the Cell Surface in Human Colon Cancer Cells Selected for Resistance to TRAIL-induced Apoptosis

    Deficient Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Death Receptor Transport to the Cell Surface in Human Colon Cancer Cells Selected for Resistance to TRAIL-... de réir Zhaoyu Jin, E. Robert McDonald, David T. Dicker, Wafik S. El‐Deiry

    Foilsithe / Cruthaithe 2004
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  4. 4
    The CDK4/6 inhibitor palbociclib synergizes with irinotecan to promote colorectal cancer cell death under hypoxia

    The CDK4/6 inhibitor palbociclib synergizes with irinotecan to promote colorectal cancer cell death under hypoxia de réir Jun Zhang, Lanlan Zhou, Shuai Zhao, David T. Dicker, Wafik S. El‐Deiry

    Foilsithe / Cruthaithe 2017
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  5. 5
    Circulating tumor cells: silent predictors of metastasis

    Circulating tumor cells: silent predictors of metastasis de réir Lanlan Zhou, David T. Dicker, Elizabeth Matthew, Wafik S. El‐Deiry, R. Katherine Alpaugh

    Foilsithe / Cruthaithe 2017
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  6. 6
    CDK1 stabilizes HIF-1α via direct phosphorylation of Ser668 to promote tumor growth

    CDK1 stabilizes HIF-1α via direct phosphorylation of Ser668 to promote tumor growth de réir Noel A. Warfel, Nathan G. Dolloff, David T. Dicker, Jozef Malysz, Wafik S. El‐Deiry

    Foilsithe / Cruthaithe 2013
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  7. 7
    Silencing of the Novel p53 Target Gene <i>Snk</i>/<i>Plk2</i> Leads to Mitotic Catastrophe in Paclitaxel (Taxol)-Exposed Cells

    Silencing of the Novel p53 Target Gene <i>Snk</i>/<i>Plk2</i> Leads to Mitotic Catastrophe in Paclitaxel (Taxol)-Exposed Cells de réir Timothy F. Burns, Peiwen Fei, Kimberly A. Scata, David T. Dicker, Wafik S. El‐Deiry

    Foilsithe / Cruthaithe 2003
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  8. 8
    The Mutant p53-Conformation Modifying Drug, CP-31398, Can Induce Apoptosis

    The Mutant p53-Conformation Modifying Drug, CP-31398, Can Induce Apoptosis de réir Rishu Takimoto, Wenge Wang, David T. Dicker, Farzan Rastinejad, Joseph P. Lyssikatos, Wafik S. El‐Deiry

    Foilsithe / Cruthaithe 2002
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  9. 9
    BRCA1 Transcriptionally Regulates Damaged DNA Binding Protein (DDB2) In the DNA Repair Response Following UV-Irradiation

    BRCA1 Transcriptionally Regulates Damaged DNA Binding Protein (DDB2) In the DNA Repair Response Following UV-Irradiation de réir Rishu Takimoto, Timothy K. MacLachlan, David T. Dicker, Yoshiro Niitsu, Toshio Mori, Wafik S. El‐Deiry

    Foilsithe / Cruthaithe 2002
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  10. 10
    Direct Repression of <i>FLIP</i> Expression by c-myc Is a Major Determinant of TRAIL Sensitivity

    Direct Repression of <i>FLIP</i> Expression by c-myc Is a Major Determinant of TRAIL Sensitivity de réir M. Ricci, Zhaoyu Jin, Michael Dews, Duonan Yu, Andrei Thomas‐Tikhonenko, David T. Dicker, Wafik S. El‐Deiry

    Foilsithe / Cruthaithe 2004
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  11. 11
    Human colon cancer stem cells are enriched by insulin-like growth factor-1 and are sensitive to figitumumab

    Human colon cancer stem cells are enriched by insulin-like growth factor-1 and are sensitive to figitumumab de réir Lori S. Hart, Nathan G. Dolloff, David T. Dicker, Constantinos Koumenis, James G. Christensen, Adda Grimberg, Wafik S. El‐Deiry

    Foilsithe / Cruthaithe 2011
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  12. 12
    miR-6883 Family miRNAs Target CDK4/6 to Induce G1 Phase Cell-Cycle Arrest in Colon Cancer Cells

    miR-6883 Family miRNAs Target CDK4/6 to Induce G1 Phase Cell-Cycle Arrest in Colon Cancer Cells de réir Amriti R. Lulla, Michael Slifker, Yan Zhou, Avital Lev, Margret B. Einarson, David T. Dicker, Wafik S. El‐Deiry

    Foilsithe / Cruthaithe 2017
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  13. 13
    Identification and enumeration of circulating tumor cells in the cerebrospinal fluid of breast cancer patients with central nervous system metastases

    Identification and enumeration of circulating tumor cells in the cerebrospinal fluid of breast cancer patients with central nervous system metastases de réir Akshal Patel, Joshua E. Allen, David T. Dicker, Kristi L. Peters, Jonas M. Sheehan, Michael Glantz, Wafik S. El‐Deiry

    Foilsithe / Cruthaithe 2011
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  14. 14
    Identification of TRAIL-inducing compounds highlights small molecule ONC201/TIC10 as a unique anti-cancer agent that activates the TRAIL pathway

    Identification of TRAIL-inducing compounds highlights small molecule ONC201/TIC10 as a unique anti-cancer agent that activates the TRAIL pathway de réir Joshua E. Allen, Gabriel Krigsfeld, Luv Patel, Patrick A. Mayes, David T. Dicker, Gen Sheng Wu, Wafik S. El‐Deiry

    Foilsithe / Cruthaithe 2015
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  15. 15
    Small-Molecule Prodigiosin Restores p53 Tumor Suppressor Activity in Chemoresistant Colorectal Cancer Stem Cells via c-Jun-Mediated ΔNp73 Inhibition and p73 Activation

    Small-Molecule Prodigiosin Restores p53 Tumor Suppressor Activity in Chemoresistant Colorectal Cancer Stem Cells via c-Jun-Mediated ΔNp73 Inhibition and p73 Activation de réir Varun V. Prabhu, Bo Hong, Joshua E. Allen, Shengliang Zhang, Amriti R. Lulla, David T. Dicker, Wafik S. El‐Deiry

    Foilsithe / Cruthaithe 2016
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  16. 16
    TNFSF10 (TRAIL), a p53 target gene that mediates p53-dependent cell death

    TNFSF10 (TRAIL), a p53 target gene that mediates p53-dependent cell death de réir Kageaki Kuribayashi, Gabriel Krigsfeld, Wenge Wang, Jing Xu, Patrick A. Mayes, David T. Dicker, Gen Sheng Wu, Wafik S. El‐Deiry

    Foilsithe / Cruthaithe 2008
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  17. 17
    The p53 target Plk2 interacts with TSC proteins impacting mTOR signaling, tumor growth, and chemosensitivity under hypoxic conditions

    The p53 target Plk2 interacts with TSC proteins impacting mTOR signaling, tumor growth, and chemosensitivity under hypoxic conditions de réir Elizabeth Matthew, Lori S. Hart, Aristotelis Astrinidis, Arunasalam Navaraj, Nathan G. Dolloff, David T. Dicker, Elizabeth P. Henske, Wafik S. El‐Deiry

    Foilsithe / Cruthaithe 2009
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  18. 18
    Death Induction by Recombinant Native TRAIL and Its Prevention by a Caspase 9 Inhibitor in Primary Human Esophageal Epithelial Cells

    Death Induction by Recombinant Native TRAIL and Its Prevention by a Caspase 9 Inhibitor in Primary Human Esophageal Epithelial Cells de réir Seok‐Hyun Kim, Kunhong Kim, Jae Kwagh, David T. Dicker, Meenhard Herlyn, Anil K. Rustgi, Youhai Chen, Wafik S. El‐Deiry

    Foilsithe / Cruthaithe 2004
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  19. 19
    Prodigiosin Rescues Deficient p53 Signaling and Antitumor Effects via Upregulating p73 and Disrupting Its Interaction with Mutant p53

    Prodigiosin Rescues Deficient p53 Signaling and Antitumor Effects via Upregulating p73 and Disrupting Its Interaction with Mutant p53 de réir Bo Hong, Varun V. Prabhu, Shengliang Zhang, A. Pieter J. van den Heuvel, David T. Dicker, Levy Kopelovich, Wafik S. El‐Deiry

    Foilsithe / Cruthaithe 2013
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  20. 20
    Sorafenib Sensitizes Solid Tumors to Apo2L/TRAIL and Apo2L/TRAIL Receptor Agonist Antibodies by the Jak2-Stat3-Mcl1 Axis

    Sorafenib Sensitizes Solid Tumors to Apo2L/TRAIL and Apo2L/TRAIL Receptor Agonist Antibodies by the Jak2-Stat3-Mcl1 Axis de réir Junaid Abdulghani, Joshua E. Allen, David T. Dicker, Yingqiu Yvette Liu, David Goldenberg, Charles D. Smith, Robin Humphreys, Wafik S. El‐Deiry

    Foilsithe / Cruthaithe 2013
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