Søgeresultater - David Sprinzak

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  1. 1
    Notch signaling in development and homeostasis

    Notch signaling in development and homeostasis af Oren Gozlan, David Sprinzak

    Udgivet 2023
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    Artigo
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  2. 2
    Biophysics of Notch Signaling

    Biophysics of Notch Signaling af David Sprinzak, Stephen C. Blacklow

    Udgivet 2021
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  3. 3
    The Canonical Notch Signaling Pathway: Structural and Biochemical Insights into Shape, Sugar, and Force

    The Canonical Notch Signaling Pathway: Structural and Biochemical Insights into Shape, Sugar, and Force af Rhett A. Kovall, Brian Gebelein, David Sprinzak, Raphael Kopan

    Udgivet 2017
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  4. 4
    Mutual Inactivation of Notch Receptors and Ligands Facilitates Developmental Patterning

    Mutual Inactivation of Notch Receptors and Ligands Facilitates Developmental Patterning af David Sprinzak, Amit Lakhanpal, Lauren LeBon, Jordi García‐Ojalvo, Michael B. Elowitz

    Udgivet 2011
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    Artigo
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  5. 5
    Fringe proteins modulate Notch-ligand cis and trans interactions to specify signaling states

    Fringe proteins modulate Notch-ligand cis and trans interactions to specify signaling states af Lauren LeBon, Tom V. Lee, David Sprinzak, Hamed Jafar‐Nejad, Michael B. Elowitz

    Udgivet 2014
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  6. 6
    Neonatal AAV gene therapy rescues hearing in a mouse model of <i>SYNE4</i> deafness

    Neonatal AAV gene therapy rescues hearing in a mouse model of <i>SYNE4</i> deafness af Shahar Taiber, Roie Cohen, Ofer Yizhar‐Barnea, David Sprinzak, Jeffrey R. Holt, Karen B. Avraham

    Udgivet 2020
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  7. 7
    Quantitative Analysis of Delta-like 1 Membrane Dynamics Elucidates the Role of Contact Geometry on Notch Signaling

    Quantitative Analysis of Delta-like 1 Membrane Dynamics Elucidates the Role of Contact Geometry on Notch Signaling af Itzhak Khait, Yuval Orsher, Ohad Golan, Udi Binshtok, Nadav Gordon-Bar, Liat Amir-Zilberstein, David Sprinzak

    Udgivet 2015
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    Artigo
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  8. 8
    Dynamic Ligand Discrimination in the Notch Signaling Pathway

    Dynamic Ligand Discrimination in the Notch Signaling Pathway af Nagarajan Nandagopal, Leah A. Santat, Lauren LeBon, David Sprinzak, Marianne Bronner‐Fraser, Michael B. Elowitz

    Udgivet 2018
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  9. 9
    MPDZ promotes DLL4-induced Notch signaling during angiogenesis

    MPDZ promotes DLL4-induced Notch signaling during angiogenesis af Fabian Tetzlaff, Mohamed Adam, Anja Feldner, Iris Moll, Amitai Menuchin, Juan Rodríguez‐Vita, David Sprinzak, Andreas Fischer

    Udgivet 2018
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  10. 10
    Genetic and Mechanical Regulation of Intestinal Smooth Muscle Development

    Genetic and Mechanical Regulation of Intestinal Smooth Muscle Development af Tyler R. Huycke, Bess M. Miller, Hasreet K. Gill, Nandan L. Nerurkar, David Sprinzak, L. Mahadevan, Clifford J. Tabin

    Udgivet 2019
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  11. 11
    Cis-interactions between Notch and Delta generate mutually exclusive signalling states

    Cis-interactions between Notch and Delta generate mutually exclusive signalling states af David Sprinzak, Amit Lakhanpal, Lauren LeBon, Leah A. Santat, Michelle E. Fontes, Graham A. Anderson, Jordi García‐Ojalvo, Michael B. Elowitz

    Udgivet 2010
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  12. 12
    Notch-Mediated Tumor-Stroma-Inflammation Networks Promote Invasive Properties and CXCL8 Expression in Triple-Negative Breast Cancer

    Notch-Mediated Tumor-Stroma-Inflammation Networks Promote Invasive Properties and CXCL8 Expression in Triple-Negative Breast Cancer af Yulia Liubomirski, Shalom Lerrer, Tsipi Meshel, Dina Morein, Linor Rubinstein-Achiasaf, David Sprinzak, Stefan Wiemann, Cindy Körner, Marcelo Ehrlich, Adit Ben‐Baruch

    Udgivet 2019
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    Artigo
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  13. 13
    Mechanical forces drive ordered patterning of hair cells in the mammalian inner ear

    Mechanical forces drive ordered patterning of hair cells in the mammalian inner ear af Roie Cohen, Liat Amir-Zilberstein, Micha Hersch, Shiran Woland, Olga Loza, Shahar Taiber, Fumio Matsuzaki, Sven Bergmann, Karen B. Avraham, David Sprinzak

    Udgivet 2020
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  14. 14
    Cell-Cell Contact Area Affects Notch Signaling and Notch-Dependent Patterning

    Cell-Cell Contact Area Affects Notch Signaling and Notch-Dependent Patterning af O. Shaya, Udi Binshtok, Micha Hersch, Dmitri Rivkin, Sheila Weinreb, Liat Amir-Zilberstein, Bassma Khamaisi, Olya Oppenheim, Ravi A. Desai, Richard J. Goodyear, Guy P. Richardson, Christopher S. Chen, David Sprinzak

    Udgivet 2017
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  15. 15
    Dynamic spatiotemporal coordination of neural stem cell fate decisions occurs through local feedback in the adult vertebrate brain

    Dynamic spatiotemporal coordination of neural stem cell fate decisions occurs through local feedback in the adult vertebrate brain af Nicolas Dray, Laure Mancini, Udi Binshtok, Félix Cheysson, Willy Supatto, Pierre Mahou, Sébastien Bedu, Sara Ortica, Emmanuel Than‐Trong, Mónika Krecsmarik, Sébastien Herbert, Jean‐Baptiste Masson, Jean-Yves Tinévez, Gabriel Lang, Emmanuel Beaurepaire, David Sprinzak, Laure Bally‐Cuif

    Udgivet 2021
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  16. 16
    Interactions of Melanoma Cells with Distal Keratinocytes Trigger Metastasis via Notch Signaling Inhibition of MITF

    Interactions of Melanoma Cells with Distal Keratinocytes Trigger Metastasis via Notch Signaling Inhibition of MITF af Tamar Golan, Arielle R. Messer, Aya Amitai-Lange, Ze’ev Melamed, Reut Ohana, Rachel E. Bell, Oxana Kapitansky, Galya Lerman, Shoshana Greenberger, Mehdi Khaled, Nira Amar, Jean Albrengues, Cédric Gaggioli, Pinchas Gonen, Yuval Tabach, David Sprinzak, Ruby Shalom‐Feuerstein, Carmit Levy

    Udgivet 2015
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  17. 17
    Endothelial Notch1 Activity Facilitates Metastasis

    Endothelial Notch1 Activity Facilitates Metastasis af Elfriede Wieland, Juan Rodríguez‐Vita, Sven S. Liebler, Carolin Mogler, Iris Moll, Stefanie E. Herberich, Elisa Espinet, Esther Herpel, Amitai Menuchin, Jenny Chang‐Claude, Michael Hoffmeister, Christoffer Gebhardt, Hermann Brenner, Andreas Trumpp, Christian W. Siebel, Markus Hecker, Jochen Utikal, David Sprinzak, Andreas Fischer

    Udgivet 2017
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  18. 18
    Notch ligand Dll4 impairs cell recruitment to aortic clusters and limits blood stem cell generation

    Notch ligand Dll4 impairs cell recruitment to aortic clusters and limits blood stem cell generation af Cristina Porcheri, Ohad Golan, Fernando J. Calero‐Nieto, Roshana Thambyrajah, Cristina Ruiz‐Herguido, Xiaonan Wang, Francesca Catto, Yolanda Guillén, Roshani Sinha, Jéssica González, Sarah Kinston, Samanta A. Mariani, Antonio Maglitto, Chris S. Vink, Elaine Dzierzak, Pierre Charbord, Berthold Göttgens, Lluı́s Espinosa, David Sprinzak, Anna Bigas

    Udgivet 2020
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  19. 19
    Roadmap for the multiscale coupling of biochemical and mechanical signals during development

    Roadmap for the multiscale coupling of biochemical and mechanical signals during development af Pierre-François Lenné, Edwin Munro, Idse Heemskerk, Aryeh Warmflash, Laura Bocanegra-Moreno, Kasumi Kishi, Anna Kicheva, Yuchen Long, Antoine Fruleux, Arezki Boudaoud, Timothy E. Saunders, Paolo Caldarelli, Arthur Michaut, Jérôme Gros, Yonit Maroudas-Sacks, Kinneret Keren, Édouard Hannezo, Zev J. Gartner, Benjamin M. Stormo, Amy Gladfelter, Alan R. Rodrigues, Amy E. Shyer, Nicolas Minc, Jean‐Léon Maître, Stefano Di Talia, Bassma Khamaisi, David Sprinzak, Sham Tlili

    Udgivet 2020
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  20. 20
    Novel Association of the NOTCH Pathway Regulator <i>MIB1</i> Gene With the Development of Bicuspid Aortic Valve

    Novel Association of the NOTCH Pathway Regulator <i>MIB1</i> Gene With the Development of Bicuspid Aortic Valve af Idit Tessler, Juliette Albuisson, Rebeca Piñeiro-Sabarís, Aline Verstraeten, Hatem Elif Kamber Kaya, Marcos Siguero-Álvarez, Guillaume Goudot, Donal MacGrogan, Ilse Luyckx, Shoshana Shpitzen, Galina Levin, Guy Kelman, Noga Reshef, Hugo Mananet, Jake Holdcraft, Jochen D. Muehlschlegel, Gina M. Peloso, Olya Oppenheim, Charles Cheng, Jean‐Michaël Mazzella, Grégor Andelfinger, Seema Mital, Per Eriksson, Clarisse Billon, Mahyar Heydarpour, Harry C. Dietz, Xavier Jeunemaı̂tre, Eran Leitersdorf, David Sprinzak, Stephen C. Blacklow, Simon C. Body, Shai Carmi, Bart Loeys, José Luís de la Pompa, Dan Gilon, Emmanuel Messas, Ronen Durst

    Udgivet 2023
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