检索结果 - David Sebastián
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Alteration of the <i>M</i>alonyl-<i>CoA</i>/Carnitine Palmitoyltransferase <i>I</i> Interaction in the β-Cell Impairs Glucose-Induced Insulin Secretion 由 Laura Herrero, Blanca Rubı́, David Sebastián, Dolors Serra, Guillermina Asins, Pierre Maechler, Marc Prentki, Fausto G. Hegardt
出版 2005Artigo -
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Disruption of mitochondrial dynamics triggers muscle inflammation through interorganellar contacts and mitochondrial DNA mislocation 由 Andrea Irazoki, Isabel Gordaliza‐Alaguero, Emma Frank, Nickolaos Nikiforos Giakoumakis, Jordi Seco, Manuel Palacı́n, Anna Gumà, Lykke Sylow, David Sebastián, António Zorzano
出版 2023Artigo -
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Identification of New Activators of Mitochondrial Fusion Reveals a Link between Mitochondrial Morphology and Pyrimidine Metabolism 由 Laia Miret‐Casals, David Sebastián, José Brea, Eva M. Rico‐Leo, Manuel Palacı́n, Pedro M. Fernández‐Salguero, Marı́a Isabel Loza, Fernando Alberício, António Zorzano
出版 2017Artigo -
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TP53INP2-dependent activation of muscle autophagy ameliorates sarcopenia and promotes healthy aging 由 David Sebastián, Marc Beltrà, Andrea Irazoki, David Sala, Pilar Aparicio, Cecilia Aris, Esmaeil Alibakhshi, Maria Rubio‐Valera, Manuel Palacı́n, Juan Castellanos, Luis Lores, António Zorzano
出版 2024Artigo -
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Coordination of mitochondrial and lysosomal homeostasis mitigates inflammation and muscle atrophy during aging 由 Andrea Irazoki, Marta Martínez‐Vicente, Pilar Aparicio, Cecilia Aris, Esmaeil Alibakhshi, Maria Rubio‐Valera, Juan Castellanos, Luis Lores, Manuel Palacı́n, Anna Gumà, António Zorzano, David Sebastián
出版 2022Artigo -
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Carnitine Palmitoyltransferase 1 Increases Lipolysis, UCP1 Protein Expression and Mitochondrial Activity in Brown Adipocytes 由 María Calderón‐Domínguez, David Sebastián, Raquel Fucho, Minéia Weber, Joan Francesc Mir, Ester García-Casarrubios, Marı́a Jesús Obregón, António Zorzano, Ángela M. Valverde, Dolors Serra, Laura Herrero
出版 2016Artigo -
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Mfn2 modulates the UPR and mitochondrial function via repression of PERK 由 Juan Pablo Muñoz, Saška Ivanova, Jana Sánchez, Paula Martínez-Cristóbal, Manuel Noguera, Ana Sancho, Angels Díaz‐Ramos, María Isabel Hernández‐Álvarez, David Sebastián, Caroline Mauvezin, Manuel Palacı́n, António Zorzano
出版 2013Artigo -
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Lack of Glycogenin Causes Glycogen Accumulation and Muscle Function Impairment 由 Giorgia Testoni, Jordi Durán, Mar Garcı́a-Rocha, Francisco Vilaplana, Antonio L. Serrano, David Sebastián, Iliana López‐Soldado, Mitchell A. Sullivan, Felipe Slebe, Marta Vilaseca, Pura Muñoz‐Cánoves, Joan J. Guinovart
出版 2017Artigo -
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Muscle-Specific IRS-1 Ser→Ala Transgenic Mice Are Protected From Fat-Induced Insulin Resistance in Skeletal Muscle 由 Katsutaro Morino, Susanne Neschen, Stefan Bilz, Saki Sono, Dimitrios N. Tsirigotis, Richard M. Reznick, Irene K. Moore, Yoshio Nagai, Varman T. Samuel, David Sebastián, Morris F. White, William Philbrick, Gerald I. Shulman
出版 2008Artigo -
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n-3 Fatty Acids Preserve Insulin Sensitivity In Vivo in a Peroxisome Proliferator–Activated Receptor-α–Dependent Manner 由 Susanne Neschen, Katsutaro Morino, Jianying Dong, Yanlin Wang-Fischer, Gary W. Cline, Anthony J. Romanelli, Jörg C. Rossbacher, Irene K. Moore, Werner Regittnig, David Sebastián Muñoz, Jung Hwan Kim, Gerald I. Shulman
出版 2007Artigo -
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Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis 由 David Sebastián, María Isabel Hernández‐Álvarez, Jessica Segalés, Eleonora Sorianello, Juan Pablo Muñoz, David Sala, Aurélie Waget, Marc Liesa, José C. Paz, Peddinti Gopalacharyulu, Matej Orešič, Sara Pich, Rémy Burcelin, Manuel Palacı́n, António Zorzano
出版 2012Artigo
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Biology
Endocrinology
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Mitochondrion
Internal medicine
Gene
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Mitochondrial DNA
Apoptosis
Autophagy
MFN2
mitochondrial fusion
Mitophagy
Skeletal muscle
Endoplasmic reticulum
Insulin
Sarcopenia
Atrophy
Beta oxidation
Carnitine
Chemistry
Disease
Fatty acid
Immunology
Insulin resistance
Metabolism
Muscle atrophy
Adipocyte