Výsledky vyhledávání - David S. Lamb
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Unusual properties of the cytochrome P450 superfamily Autor David C. Lamb, Michael R. Waterman
Vydáno 2013Revisão -
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Structure-Functional Characterization of Cytochrome P450 Sterol 14α-Demethylase (CYP51B) from Aspergillus fumigatus and Molecular Basis for the Development of Antifungal Drugs Autor Tatiana Y. Hargrove, Z. Wawrzak, David C. Lamb, F. Peter Guengerich, Galina I. Lepesheva
Vydáno 2015Artigo -
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Resistance to amphotericin B associated with defective sterol<i>Î</i><sup>8â7</sup>isomerase in a<i>Cryptococcus neoformans</i>strain from an AIDS patient Autor Steven L. Kelly, David C. Lamb, Mark Taylor, Andrew J. Corran, Brian C. Baldwin, William G. Powderly
Vydáno 1994Artigo -
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Resistance to fluconazole and cross‐resistance to amphotericin B in <i>Candida albicans</i> from AIDS patients caused by defective sterol Δ<sup>5,6</sup>‐desaturation Autor Steven L. Kelly, David C. Lamb, Diane Kelly, N. J. Manning, Juergen Loeffler, Holger Hebart, Ulrike Schumacher, Hermann Einsele
Vydáno 1997Artigo -
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Identification of Potent and Selective Inhibitors of <i>Acanthamoeba</i>: Structural Insights into Sterol 14α-Demethylase as a Key Drug Target Autor Tatiana Y. Hargrove, David C. Lamb, Z. Wawrzak, Marcus Hull, Steven L. Kelly, F. Peter Guengerich, Galina I. Lepesheva
Vydáno 2024Artigo -
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The Mechanism of the Acyl-Carbon Bond Cleavage Reaction Catalyzed by Recombinant Sterol 14α-Demethylase of Candida albicans (Other Names Are: Lanosterol 14α-Demethylase, P-45014DM,... Autor Akbar Z. Shyadehi, David C. Lamb, Steven L. Kelly, Diane Kelly, Wolf‐Hagen Schunck, J. Neville Wright, David L. Corina, Muhammad Akhtar
Vydáno 1996Artigo -
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The Mutation T315A in Candida albicans Sterol 14α-Demethylase Causes Reduced Enzyme Activity and Fluconazole Resistance through Reduced Affinity Autor David C. Lamb, Diane Kelly, Wolf‐Hagen Schunck, Akbar Z. Shyadehi, Muhammed Akhtar, David J. Lowe, Brian C. Baldwin, Steven L. Kelly
Vydáno 1997Artigo -
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Vyhledávací nástroje:
Související témata
Biochemistry
Biology
Chemistry
Cholesterol
Enzyme
Gene
Sterol
Microbiology
Cytochrome P450
Antifungal
Fluconazole
Genetics
Candida albicans
Cytochrome
Azole
Bacteria
Demethylase
Epigenetics
Internal medicine
Medicine
Stereochemistry
Streptomyces
Streptomyces coelicolor
Cancer
Ergosterol
Lanosterol
Pharmacology
Prostate cancer
Active site
Corpus albicans