نتائج بحث المؤلف

1

Unusual properties of the cytochrome P450 superfamily حسب David C. Lamb, Michael R. Waterman

منشور في 2013

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Revisão

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2

Y132H substitution inCandida albicanssterol 14Î±-demethylase confers fluconazole resistance by preventing binding to haem حسب Steven L. Kelly, David C. Lamb, Diane Kelly

منشور في 1999

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Artigo

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3

Structure–Function Analysis of the Self-Sufficient CYP102 Family Provides New Insights into Their Biochemistry حسب Tiara Padayachee, David C. Lamb, David R. Nelson, Khajamohiddin Syed

منشور في 2025

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Artigo

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4

The R467K Amino Acid Substitution in Candida albicans Sterol 14α-Demethylase Causes Drug Resistance through Reduced Affinity حسب David C. Lamb, Diane Kelly, Theodore C. White, Steven L. Kelly

منشور في 2000

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Artigo

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5

Characterization of Saccharomyces cerevisiae CYP61, Sterol Δ22-Desaturase, and Inhibition by Azole Antifungal Agents حسب Steven L. Kelly, David C. Lamb, Brian C. Baldwin, Andrew J. Corran, Diane Kelly

منشور في 1997

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Artigo

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6

Multiple Molecular Mechanisms Contribute to a Stepwise Development of Fluconazole Resistance in Clinical Candida albicans Strains حسب R. Franz, Steven L. Kelly, David C. Lamb, Diane Kelly, Markus Ruhnke, Joachim Morschhäuser

منشور في 1998

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Artigo

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7

Structure-Functional Characterization of Cytochrome P450 Sterol 14α-Demethylase (CYP51B) from Aspergillus fumigatus and Molecular Basis for the Development of Antifungal Drugs حسب Tatiana Y. Hargrove, Z. Wawrzak, David C. Lamb, F. Peter Guengerich, Galina I. Lepesheva

منشور في 2015

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Artigo

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8

Genetic and structural analyses of cytochrome P450 hydroxylases in sex hormone biosynthesis: Sequential origin and subsequent coevolution حسب Jared V. Goldstone, Munirathinam Sundaramoorthy, Bin Zhao, Michael R. Waterman, John J. Stegeman, David C. Lamb

منشور في 2015

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Artigo

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9

Resistance to amphotericin B associated with defective sterolÎ8â7isomerase in aCryptococcus neoformansstrain from an AIDS patient حسب Steven L. Kelly, David C. Lamb, Mark Taylor, Andrew J. Corran, Brian C. Baldwin, William G. Powderly

منشور في 1994

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Artigo

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10

Biosynthesis of the Sesquiterpene Antibiotic Albaflavenone in Streptomyces coelicolor A3(2) حسب Bin Zhao, Xin Lin, Lei Li, David C. Lamb, Steven L. Kelly, Michael R. Waterman, David E. Cane

منشور في 2008

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Artigo

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11

Resistance to fluconazole and cross‐resistance to amphotericin B in Candida albicans from AIDS patients caused by defective sterol Δ5,6‐desaturation حسب Steven L. Kelly, David C. Lamb, Diane Kelly, N. J. Manning, Juergen Loeffler, Holger Hebart, Ulrike Schumacher, Hermann Einsele

منشور في 1997

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Artigo

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12

Neuropsychologic impairment in adult bone marrow transplant candidates حسب Michael A. Andrykowski, Frederick A. Schmitt, Megan E. Gregg, Marianne I. Brady, David G. Lamb, P. Jean Henslee‐Downey

منشور في 1992

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Artigo

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محفوظ في:
13

Identification of Potent and Selective Inhibitors of Acanthamoeba: Structural Insights into Sterol 14α-Demethylase as a Key Drug Target حسب Tatiana Y. Hargrove, David C. Lamb, Z. Wawrzak, Marcus Hull, Steven L. Kelly, F. Peter Guengerich, Galina I. Lepesheva

منشور في 2024

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Artigo

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14

The First Virally Encoded Cytochrome P450 حسب David C. Lamb, Li Lei, Andrew G. S. Warrilow, Galina I. Lepesheva, Jonathan G.L. Mullins, Michael R. Waterman, Steven L. Kelly

منشور في 2009

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Artigo

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15

The Mechanism of the Acyl-Carbon Bond Cleavage Reaction Catalyzed by Recombinant Sterol 14α-Demethylase of Candida albicans (Other Names Are: Lanosterol 14α-Demethylase, P-45014DM,... حسب Akbar Z. Shyadehi, David C. Lamb, Steven L. Kelly, Diane Kelly, Wolf‐Hagen Schunck, J. Neville Wright, David L. Corina, Muhammad Akhtar

منشور في 1996

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Artigo

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16

The Mutation T315A in Candida albicans Sterol 14α-Demethylase Causes Reduced Enzyme Activity and Fluconazole Resistance through Reduced Affinity حسب David C. Lamb, Diane Kelly, Wolf‐Hagen Schunck, Akbar Z. Shyadehi, Muhammed Akhtar, David J. Lowe, Brian C. Baldwin, Steven L. Kelly

منشور في 1997

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Artigo

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17

Crystal Structure of Albaflavenone Monooxygenase Containing a Moonlighting Terpene Synthase Active Site حسب Bin Zhao, Lei Li, Dmitry G. Vassylyev, Xin Lin, David E. Cane, Steven L. Kelly, Hang Yuan, David C. Lamb, Michael R. Waterman

منشور في 2009

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Artigo

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18

Azole Binding Properties of Candida albicans Sterol 14-α Demethylase (CaCYP51) حسب Andrew G. S. Warrilow, Claire M. Martel, Josie E. Parker, Nadja Rodrigues de Melo, David C. Lamb, W. David Nes, Diane Kelly, Steven L. Kelly

منشور في 2010

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Artigo

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19

The Cytochrome P450 Complement (CYPome) of Streptomyces coelicolor A3(2) حسب David C. Lamb, Tove Skaug, Honglin Song, Colin J. Jackson, Larissa M. Podust, Michael R. Waterman, Douglas B. Kell, Diane Kelly, Steven L. Kelly

منشور في 2002

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Artigo

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20

The 1.92-Å Structure of Streptomyces coelicolor A3(2) CYP154C1 حسب Larissa M. Podust, Youngchang Kim, Miharu Arase, Benjamin A. Neely, Brian J. Beck, Horacio Bach, David H. Sherman, David C. Lamb, Steven Kelly, Michael R. Waterman

منشور في 2003

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Artigo

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محفوظ في:

Unusual properties of the cytochrome P450 superfamily حسب David C. Lamb, Michael R. Waterman

Y132H substitution in<i>Candida albicans</i>sterol 14Î±-demethylase confers fluconazole resistance by preventing binding to haem حسب Steven L. Kelly, David C. Lamb, Diane Kelly

Structure–Function Analysis of the Self-Sufficient CYP102 Family Provides New Insights into Their Biochemistry حسب Tiara Padayachee, David C. Lamb, David R. Nelson, Khajamohiddin Syed

The R467K Amino Acid Substitution in <i>Candida albicans</i> Sterol 14α-Demethylase Causes Drug Resistance through Reduced Affinity حسب David C. Lamb, Diane Kelly, Theodore C. White, Steven L. Kelly

Characterization of Saccharomyces cerevisiae CYP61, Sterol Δ22-Desaturase, and Inhibition by Azole Antifungal Agents حسب Steven L. Kelly, David C. Lamb, Brian C. Baldwin, Andrew J. Corran, Diane Kelly

Multiple Molecular Mechanisms Contribute to a Stepwise Development of Fluconazole Resistance in Clinical <i>Candida albicans</i> Strains حسب R. Franz, Steven L. Kelly, David C. Lamb, Diane Kelly, Markus Ruhnke, Joachim Morschhäuser

Structure-Functional Characterization of Cytochrome P450 Sterol 14α-Demethylase (CYP51B) from Aspergillus fumigatus and Molecular Basis for the Development of Antifungal Drugs حسب Tatiana Y. Hargrove, Z. Wawrzak, David C. Lamb, F. Peter Guengerich, Galina I. Lepesheva

Genetic and structural analyses of cytochrome P450 hydroxylases in sex hormone biosynthesis: Sequential origin and subsequent coevolution حسب Jared V. Goldstone, Munirathinam Sundaramoorthy, Bin Zhao, Michael R. Waterman, John J. Stegeman, David C. Lamb

Resistance to amphotericin B associated with defective sterol<i>Î</i><sup>8â7</sup>isomerase in a<i>Cryptococcus neoformans</i>strain from an AIDS patient حسب Steven L. Kelly, David C. Lamb, Mark Taylor, Andrew J. Corran, Brian C. Baldwin, William G. Powderly

Biosynthesis of the Sesquiterpene Antibiotic Albaflavenone in Streptomyces coelicolor A3(2) حسب Bin Zhao, Xin Lin, Lei Li, David C. Lamb, Steven L. Kelly, Michael R. Waterman, David E. Cane

Neuropsychologic impairment in adult bone marrow transplant candidates حسب Michael A. Andrykowski, Frederick A. Schmitt, Megan E. Gregg, Marianne I. Brady, David G. Lamb, P. Jean Henslee‐Downey

Identification of Potent and Selective Inhibitors of <i>Acanthamoeba</i>: Structural Insights into Sterol 14α-Demethylase as a Key Drug Target حسب Tatiana Y. Hargrove, David C. Lamb, Z. Wawrzak, Marcus Hull, Steven L. Kelly, F. Peter Guengerich, Galina I. Lepesheva

The First Virally Encoded Cytochrome P450 حسب David C. Lamb, Li Lei, Andrew G. S. Warrilow, Galina I. Lepesheva, Jonathan G.L. Mullins, Michael R. Waterman, Steven L. Kelly

The Mutation T315A in Candida albicans Sterol 14α-Demethylase Causes Reduced Enzyme Activity and Fluconazole Resistance through Reduced Affinity حسب David C. Lamb, Diane Kelly, Wolf‐Hagen Schunck, Akbar Z. Shyadehi, Muhammed Akhtar, David J. Lowe, Brian C. Baldwin, Steven L. Kelly

Crystal Structure of Albaflavenone Monooxygenase Containing a Moonlighting Terpene Synthase Active Site حسب Bin Zhao, Lei Li, Dmitry G. Vassylyev, Xin Lin, David E. Cane, Steven L. Kelly, Hang Yuan, David C. Lamb, Michael R. Waterman

Azole Binding Properties of <i>Candida albicans</i> Sterol 14-α Demethylase (CaCYP51) حسب Andrew G. S. Warrilow, Claire M. Martel, Josie E. Parker, Nadja Rodrigues de Melo, David C. Lamb, W. David Nes, Diane Kelly, Steven L. Kelly

The Cytochrome P450 Complement (CYPome) of Streptomyces coelicolor A3(2) حسب David C. Lamb, Tove Skaug, Honglin Song, Colin J. Jackson, Larissa M. Podust, Michael R. Waterman, Douglas B. Kell, Diane Kelly, Steven L. Kelly

The 1.92-Å Structure of Streptomyces coelicolor A3(2) CYP154C1 حسب Larissa M. Podust, Youngchang Kim, Miharu Arase, Benjamin A. Neely, Brian J. Beck, Horacio Bach, David H. Sherman, David C. Lamb, Steven Kelly, Michael R. Waterman

نتائج البحث - David S. Lamb

Unusual properties of the cytochrome P450 superfamily حسب David C. Lamb, Michael R. Waterman

Y132H substitution in<i>Candida albicans</i>sterol 14Î±-demethylase confers fluconazole resistance by preventing binding to haem حسب Steven L. Kelly, David C. Lamb, Diane Kelly

Structure–Function Analysis of the Self-Sufficient CYP102 Family Provides New Insights into Their Biochemistry حسب Tiara Padayachee, David C. Lamb, David R. Nelson, Khajamohiddin Syed

The R467K Amino Acid Substitution in <i>Candida albicans</i> Sterol 14α-Demethylase Causes Drug Resistance through Reduced Affinity حسب David C. Lamb, Diane Kelly, Theodore C. White, Steven L. Kelly

Characterization of Saccharomyces cerevisiae CYP61, Sterol Δ22-Desaturase, and Inhibition by Azole Antifungal Agents حسب Steven L. Kelly, David C. Lamb, Brian C. Baldwin, Andrew J. Corran, Diane Kelly

Multiple Molecular Mechanisms Contribute to a Stepwise Development of Fluconazole Resistance in Clinical <i>Candida albicans</i> Strains حسب R. Franz, Steven L. Kelly, David C. Lamb, Diane Kelly, Markus Ruhnke, Joachim Morschhäuser

Structure-Functional Characterization of Cytochrome P450 Sterol 14α-Demethylase (CYP51B) from Aspergillus fumigatus and Molecular Basis for the Development of Antifungal Drugs حسب Tatiana Y. Hargrove, Z. Wawrzak, David C. Lamb, F. Peter Guengerich, Galina I. Lepesheva

Genetic and structural analyses of cytochrome P450 hydroxylases in sex hormone biosynthesis: Sequential origin and subsequent coevolution حسب Jared V. Goldstone, Munirathinam Sundaramoorthy, Bin Zhao, Michael R. Waterman, John J. Stegeman, David C. Lamb

Resistance to amphotericin B associated with defective sterol<i>Î</i><sup>8â7</sup>isomerase in a<i>Cryptococcus neoformans</i>strain from an AIDS patient حسب Steven L. Kelly, David C. Lamb, Mark Taylor, Andrew J. Corran, Brian C. Baldwin, William G. Powderly

Biosynthesis of the Sesquiterpene Antibiotic Albaflavenone in Streptomyces coelicolor A3(2) حسب Bin Zhao, Xin Lin, Lei Li, David C. Lamb, Steven L. Kelly, Michael R. Waterman, David E. Cane

Neuropsychologic impairment in adult bone marrow transplant candidates حسب Michael A. Andrykowski, Frederick A. Schmitt, Megan E. Gregg, Marianne I. Brady, David G. Lamb, P. Jean Henslee‐Downey

Identification of Potent and Selective Inhibitors of <i>Acanthamoeba</i>: Structural Insights into Sterol 14α-Demethylase as a Key Drug Target حسب Tatiana Y. Hargrove, David C. Lamb, Z. Wawrzak, Marcus Hull, Steven L. Kelly, F. Peter Guengerich, Galina I. Lepesheva

The First Virally Encoded Cytochrome P450 حسب David C. Lamb, Li Lei, Andrew G. S. Warrilow, Galina I. Lepesheva, Jonathan G.L. Mullins, Michael R. Waterman, Steven L. Kelly

The Mutation T315A in Candida albicans Sterol 14α-Demethylase Causes Reduced Enzyme Activity and Fluconazole Resistance through Reduced Affinity حسب David C. Lamb, Diane Kelly, Wolf‐Hagen Schunck, Akbar Z. Shyadehi, Muhammed Akhtar, David J. Lowe, Brian C. Baldwin, Steven L. Kelly

Crystal Structure of Albaflavenone Monooxygenase Containing a Moonlighting Terpene Synthase Active Site حسب Bin Zhao, Lei Li, Dmitry G. Vassylyev, Xin Lin, David E. Cane, Steven L. Kelly, Hang Yuan, David C. Lamb, Michael R. Waterman

Azole Binding Properties of <i>Candida albicans</i> Sterol 14-α Demethylase (CaCYP51) حسب Andrew G. S. Warrilow, Claire M. Martel, Josie E. Parker, Nadja Rodrigues de Melo, David C. Lamb, W. David Nes, Diane Kelly, Steven L. Kelly

The Cytochrome P450 Complement (CYPome) of Streptomyces coelicolor A3(2) حسب David C. Lamb, Tove Skaug, Honglin Song, Colin J. Jackson, Larissa M. Podust, Michael R. Waterman, Douglas B. Kell, Diane Kelly, Steven L. Kelly

The 1.92-Å Structure of Streptomyces coelicolor A3(2) CYP154C1 حسب Larissa M. Podust, Youngchang Kim, Miharu Arase, Benjamin A. Neely, Brian J. Beck, Horacio Bach, David H. Sherman, David C. Lamb, Steven Kelly, Michael R. Waterman

أدوات البحث:

موضوعات ذات صلة

Resistance to amphotericin B associated with defective sterol<i>Î</i><sup>8â7</sup>isomerase in a<i>Cryptococcus neoformans</i>strain from an AIDS patient حسب Steven L. Kelly, David C. Lamb, Mark Taylor, Andrew J. Corran, Brian C. Baldwin, William G. Powderly