Resultats de la cerca - David P. Cook

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  1. 1
    Context specificity of the EMT transcriptional response

    Context specificity of the EMT transcriptional response per David P. Cook, Barbara C. Vanderhyden

    Publicat 2020
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  2. 2
    Transcriptional census of epithelial-mesenchymal plasticity in cancer

    Transcriptional census of epithelial-mesenchymal plasticity in cancer per David P. Cook, Barbara C. Vanderhyden

    Publicat 2022
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  3. 3
    Wingless inactivates glycogen synthase kinase-3 via an intracellular signalling pathway which involves a protein kinase C.

    Wingless inactivates glycogen synthase kinase-3 via an intracellular signalling pathway which involves a protein kinase C. per David P. Cook, Michael Fry, K. Hughes, Rushika Sumathipala, James R. Woodgett, Trevor Dale

    Publicat 1996
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  4. 4
    Absolute scaling of single-cell transcriptomes identifies pervasive hypertranscription in adult stem and progenitor cells

    Absolute scaling of single-cell transcriptomes identifies pervasive hypertranscription in adult stem and progenitor cells per Yun‐Kyo Kim, Brandon Cho, David P. Cook, Dan Trcka, Jeffrey L. Wrana, Miguel Ramalho‐Santos

    Publicat 2023
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  5. 5
    Interaction of Axin and Dvl-2 proteins regulates Dvl-2-stimulated TCF-dependent transcription

    Interaction of Axin and Dvl-2 proteins regulates Dvl-2-stimulated TCF-dependent transcription per Matthew J. Smalley, Elizabeth Sara, Hugh Paterson, Stuart Naylor, David P. Cook, Hiran Jayatilake, Lee G.D. Fryer, Lisa Hutchinson, Michael Fry, Trevor Dale

    Publicat 1999
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  6. 6
    Single-cell transcriptomic atlas of lung microvascular regeneration after targeted endothelial cell ablation

    Single-cell transcriptomic atlas of lung microvascular regeneration after targeted endothelial cell ablation per Rafael Soares Godoy, Nicholas D Cober, David P. Cook, Emma R. McCourt, Yupu Deng, Liyuan Wang, Kenny Schlosser, Katelynn Rowe, Duncan J. Stewart

    Publicat 2023
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  7. 7
    Identification of novel lipid droplet factors that regulate lipophagy and cholesterol efflux in macrophage foam cells

    Identification of novel lipid droplet factors that regulate lipophagy and cholesterol efflux in macrophage foam cells per Sabrina Robichaud, Garrett Fairman, Viyashini Vijithakumar, Esther Mak, David P. Cook, Alexander R. Pelletier, Sylvain Huard, Barbara C. Vanderhyden, Daniel Figeys, Mathieu Lavallée‐Adam, Kristin Baetz, Mireille Ouimet

    Publicat 2021
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  8. 8
    Single cell transcriptomic analysis of murine lung development on hyperoxia-induced damage

    Single cell transcriptomic analysis of murine lung development on hyperoxia-induced damage per Maria Hurskainen, Ivana Mižíková, David P. Cook, Noora Andersson, Chanèle Cyr-Depauw, Flore Lesage, Emmi Helle, Laurent Renesme, Robert P. Jankov, Markku Heikinheimo, Barbara C. Vanderhyden, Bernard Thébaud

    Publicat 2021
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  9. 9
    Paving the physician-scientist career path: from grassroots gathering to national forum

    Paving the physician-scientist career path: from grassroots gathering to national forum per Kyu Y. Rhee, Charles W. Emala, Emily J. Gallagher, Don C. Rockey, Patrick J Hu, Jatin M. Vyas, David P. Cook, Tiffany C. Scharschmidt, Olujimi A. Ajijola, Christopher S. Williams

    Publicat 2025
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  10. 10
    Loss of LATS1 and LATS2 promotes ovarian tumor formation by enhancing AKT activity and PD-L1 expression

    Loss of LATS1 and LATS2 promotes ovarian tumor formation by enhancing AKT activity and PD-L1 expression per Yalun Zhu, Atefeh Abedini, Galaxia M. Rodriguez, Curtis W. McCloskey, John Abou‐Hamad, Omar Salah Salah, Janie Larocque, Mayra Tsoi, Derek Boerboom, David P. Cook, Barbara C. Vanderhyden

    Publicat 2025
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  11. 11
    FGL2 promotes tumour growth and attenuates infiltration of activated immune cells in melanoma and ovarian cancer models

    FGL2 promotes tumour growth and attenuates infiltration of activated immune cells in melanoma and ovarian cancer models per Kristianne J.C. Galpin, Galaxia M. Rodriguez, Vincent Maranda, David P. Cook, Elizabeth Macdonald, Humaira Murshed, Zhao Shan, Curtis W. McCloskey, Andrzej Chruscinski, Gary Levy, Michele Ardolino, Barbara C. Vanderhyden

    Publicat 2024
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  12. 12
    A Comparative Analysis of Imaging-Based Spatial Transcriptomics Platforms

    A Comparative Analysis of Imaging-Based Spatial Transcriptomics Platforms per David P. Cook, Kirk B. Jensen, Kellie Wise, Michael J. Roach, Felipe Segato Dezem, Natalie K. Ryan, Michel Zamojski, Ioannis S. Vlachos, Simon Knott, Lisa M. Butler, Jeffrey L. Wrana, Nicholas E. Banovich, Jasmine Plummer, Luciano G. Martelotto

    Publicat 2023
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  13. 13
    Metformin Abrogates Age-Associated Ovarian Fibrosis

    Metformin Abrogates Age-Associated Ovarian Fibrosis per Curtis W. McCloskey, David P. Cook, Brendan S. Kelly, Féryel Azzi, Christian H. Allen, Amanda Forsyth, Jeremy Upham, Katey J. Rayner, Douglas A. Gray, Robert W. Boyd, Sangeeta Murugkar, Bernard Lo, Dominique Trudel, Mary K. Senterman, Barbara C. Vanderhyden

    Publicat 2019
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  14. 14
    When killers become thieves: Trogocytosed PD-1 inhibits NK cells in cancer

    When killers become thieves: Trogocytosed PD-1 inhibits NK cells in cancer per Mohamed S. Hasim, Marie Marotel, Jonathan J. Hodgins, Elisabetta Vulpis, Olivia Joan Makinson, Sara Asif, Han‐Yu Shih, Amit Scheer, Olivia MacMillan, Felipe Gimenes Alonso, Kelly P. Burke, David P. Cook, Rui Li, Maria Teresa Petrucci, Angela Santoni, Padraic G. Fallon, Arlene H. Sharpe, Giuseppe Sciumè, André Veillette, Alessandra Zingoni, Douglas A. Gray, Arleigh McCurdy, Michele Ardolino

    Publicat 2022
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  15. 15
    RIPK1 gene variants associate with obesity in humans and can be therapeutically silenced to reduce obesity in mice

    RIPK1 gene variants associate with obesity in humans and can be therapeutically silenced to reduce obesity in mice per Denuja Karunakaran, Adam W. Turner, Anne‐Claire Duchez, Sébastien Soubeyrand, Adil Rasheed, David Smyth, David P. Cook, Majid Nikpay, Joshua W. Kandiah, Calvin Pan, Michèle Geoffrion, Richard Lee, Ludovic Boytard, Hailey Wyatt, My-Anh Nguyen, Paulina Lau, Markku Laakso, Bhama Ramkhelawon, Marcus Alvarez, Kirsi H. Pietiläinen, Päivi Pajukanta, Barbara C. Vanderhyden, Peter Liu, Scott B. Berger, Peter J. Gough, John Bertin, Mary‐Ellen Harper, Aldons J. Lusis, Ruth McPherson, Katey J. Rayner

    Publicat 2020
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  16. 16
    Heterogeneity-driven phenotypic plasticity and treatment response in branched-organoid models of pancreatic ductal adenocarcinoma

    Heterogeneity-driven phenotypic plasticity and treatment response in branched-organoid models of pancreatic ductal adenocarcinoma per Aristeidis Papargyriou, Mulham Najajreh, David P. Cook, Carlo H. Maurer, Stefanie Bärthel, Hendrik A. Messal, S. Ravichandran, Till Richter, Moritz Knolle, Thomas J. Metzler, Aditi Shastri, Rupert Öllinger, Jeff S. Jasper, Laura Schmidleitner, Surui Wang, Christian Schneeweis, Hellen Ishikawa‐Ankerhold, Thomas Engleitner, Laura Mataite, Mariia Semina, Hussein Trabulssi, Sebastian Lange, Aashreya Ravichandra, Maximilian Schuster, Sebastian Mueller, Katja Peschke, Arlett Schäfer, Sophie Dobiasch, Stephanie E. Combs, Roland M. Schmid, Andreas R. Bausch, Rickmer Braren, Irina Heid, Christina Scheel, Günter Schneider, Anja Zeigerer, Malte D. Luecken, Katja Steiger, Georgios Kaissis, Jacco van Rheenen, Fabian J. Theis, Dieter Saur, Roland Rad, Maximilian Reichert

    Publicat 2024
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