Výsledky vyhledávání - David Mengel

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  1. 1
    α 1-antitrypsin modulates microglial-mediated neuroinflammation and protects microglial cells from amyloid-β-induced toxicity

    α 1-antitrypsin modulates microglial-mediated neuroinflammation and protects microglial cells from amyloid-β-induced toxicity Autor Maike Gold, Amalia M. Dolga, Janine Koepke, David Mengel, Carsten Culmsee, Richard Dodel, Andreas Rembert Koczulla, Jan‐Philipp Bach

    Vydáno 2014
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  2. 2
    Systemic inflammation relates to neuroaxonal damage associated with long-term cognitive dysfunction in COVID-19 patients

    Systemic inflammation relates to neuroaxonal damage associated with long-term cognitive dysfunction in COVID-19 patients Autor Harmke B. Duindam, David Mengel, Matthijs Kox, Jens Göpfert, Roy P. C. Kessels, Matthis Synofzik, Peter Pickkers, Wilson F. Abdo

    Vydáno 2024
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  3. 3
    Target engagement in an alzheimer trial: Crenezumab lowers amyloid β oligomers in cerebrospinal fluid

    Target engagement in an alzheimer trial: Crenezumab lowers amyloid β oligomers in cerebrospinal fluid Autor Ting Yang, Yifan Dang, Beth L. Ostaszewski, David Mengel, Verena Steffen, Christina Rabe, Tobias Bittner, Dominic M. Walsh, Dennis J. Selkoe

    Vydáno 2019
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  4. 4
    miR-212 and miR-132 Are Downregulated in Neurally Derived Plasma Exosomes of Alzheimer’s Patients

    miR-212 and miR-132 Are Downregulated in Neurally Derived Plasma Exosomes of Alzheimer’s Patients Autor Jean‐Sébastien Diana, David Mengel, Maja Mustapić, Wen Liu, Dennis J. Selkoe, Dimitrios Kapogiannis, Douglas Galasko, Robert A. Rissman, David A. Bennett, Dominic M. Walsh

    Vydáno 2019
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  5. 5
    Longitudinal plasma p-tau217 is increased in early stages of Alzheimer’s disease

    Longitudinal plasma p-tau217 is increased in early stages of Alzheimer’s disease Autor Niklas Mattsson, Shorena Janelidze, Sebastian Palmqvist, Nicholas Cullen, Anna L. Svenningsson, Olof Strandberg, David Mengel, Dominic M. Walsh, Erik Stomrud, Jeffrey L. Dage, Oskar Hansson

    Vydáno 2020
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  6. 6
    Detection of Aggregation-Competent Tau in Neuron-Derived Extracellular Vesicles

    Detection of Aggregation-Competent Tau in Neuron-Derived Extracellular Vesicles Autor Francesc X. Guix, Grant T. Corbett, Diana Cha, Maja Mustapić, Wen Liu, David Mengel, Zhicheng Chen, Elena Aïkawa, Tracy L. Young‐Pearse, Dimitrios Kapogiannis, Dennis J. Selkoe, Dominic M. Walsh

    Vydáno 2018
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  7. 7
    Transmission of amyloid-β protein pathology from cadaveric pituitary growth hormone

    Transmission of amyloid-β protein pathology from cadaveric pituitary growth hormone Autor Silvia A. Purro, Mark A. Farrow, Jacqueline M. Linehan, Tamsin Nazari, David X. Thomas, Zhicheng Chen, David Mengel, Takashi Saito, Takaomi C. Saido, Peter Rudge, Sebastian Brandner, Dominic M. Walsh, John Collinge

    Vydáno 2018
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  8. 8
    Learnings about the complexity of extracellular tau aid development of a blood‐based screen for Alzheimer's disease

    Learnings about the complexity of extracellular tau aid development of a blood‐based screen for Alzheimer's disease Autor Zhicheng Chen, David Mengel, Ashvini Keshavan, Robert A. Rissman, Andrew Billinton, Michael S. Perkinton, Jennifer Percival‐Alwyn, Aaron P. Schultz, Michael J Properzi, Keith A. Johnson, Dennis J. Selkoe, Reisa A. Sperling, Purvish P. Patel, Henrik Zetterberg, Douglas Galasko, Jonathan M. Schott, Dominic M. Walsh

    Vydáno 2018
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  9. 9
    Serum IL-6, sAXL, and YKL-40 as systemic correlates of reduced brain structure and function in Alzheimer’s disease: results from the DELCODE study

    Serum IL-6, sAXL, and YKL-40 as systemic correlates of reduced brain structure and function in Alzheimer’s disease: results from the DELCODE study Autor Frederic Brosseron, Anne Maaß, Luca Kleineidam, Kishore Aravind Ravichandran, Carl‐Christian Kolbe, Steffen Wolfsgruber, Francesco Santarelli, Lisa M. Häsler, Róisín M. McManus, Christina Ising, Sandra Röske, Oliver Peters, Nicoleta Carmen Cosma, Luisa‐Sophie Schneider, Xiao Wang, Josef Priller, Eike Spruth, Slawek Altenstein, Anja Schneider, Klaus Fließbach, Jens Wiltfang, Björn H. Schott, Katharina Büerger, Daniel Janowitz, Martin Dichgans, Robert Perneczky, Boris‐Stephan Rauchmann, Stefan Teipel, Ingo Kilimann, Doreen Görß, Christoph Laske, Matthias H. Munk, Emrah Düzel, Renat Yakupow, Laura Dobisch, Coraline D. Metzger, Wenzel Glanz, Michael Ewers, Peter Dechent, John­–Dylan Haynes, Klaus Scheffler, Nina Roy, Ayda Rostamzadeh, Annika Spottke, Alfredo Ramı́rez, David Mengel, Matthis Synofzik, Mathias Jucker, Eicke Latz, Frank Jessen, Michael Wagner, Michael T. Heneka

    Vydáno 2023
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  10. 10
    Different inflammatory signatures based on CSF biomarkers relate to preserved or diminished brain structure and cognition

    Different inflammatory signatures based on CSF biomarkers relate to preserved or diminished brain structure and cognition Autor Dayana Hayek, Gabriel Ziegler, Luca Kleineidam, Frederic Brosseron, Aditya Nemali, Niklas Vockert, Kishore Aravind Ravichandran, Matthew J. Betts, Oliver Peters, Luisa‐Sophie Schneider, Xiao Wang, Josef Priller, Slawek Altenstein, Anja Schneider, Klaus Fließbach, Jens Wiltfang, Claudia Bartels, Ayda Rostamzadeh, Wenzel Glanz, Katharina Büerger, Daniel Janowitz, Robert Perneczky, Boris‐Stephan Rauchmann, Stefan Teipel, Ingo Kilimann, Christoph Laske, David Mengel, Matthis Synofzik, Matthias H. Munk, Annika Spottke, Nina Roy, Sandra Roeske, Elizabeth Kuhn, Alfredo Ramı́rez, Laura Dobisch, Matthias Schmid, Moritz Berger, Steffen Wolfsgruber, Renat Yakupov, Stefan Hetzer, Peter Dechent, Michael Ewers, Klaus Scheffler, Björn H. Schott, Stefanie Schreiber, Adelina Orellana, Itziar de Rojas, Marta Marquié, Merçé Boada, Oscar Sotolongo, Pablo García‐González, Raquel Puerta, Emrah Düzel, Frank Jessen, Michael Wagner, A. Macaya Ruíz, Michael T. Heneka, Anne Maaß

    Vydáno 2024
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  11. 11
    Soluble TAM receptors sAXL and sTyro3 predict structural and functional protection in Alzheimer’s disease

    Soluble TAM receptors sAXL and sTyro3 predict structural and functional protection in Alzheimer’s disease Autor Frederic Brosseron, Anne Maaß, Luca Kleineidam, Kishore Aravind Ravichandran, Pablo García‐González, Róisín M. McManus, Christina Ising, Francesco Santarelli, Carl‐Christian Kolbe, Lisa M. Häsler, Steffen Wolfsgruber, Marta Marquié, Merçé Boada, Adelina Orellana, Itziar de Rojas, Sandra Röske, Oliver Peters, Nicoleta Carmen Cosma, Arda Can Cetindag, Xiao Wang, Josef Priller, Eike Spruth, Slawek Altenstein, Anja Schneider, Klaus Fließbach, Jens Wiltfang, Björn H. Schott, Katharina Bürger, Daniel Janowitz, Martin Dichgans, Robert Perneczky, Boris‐Stephan Rauchmann, Stefan Teipel, Ingo Kilimann, Doreen Göerß, Christoph Laske, Matthias H. Munk, Emrah Düzel, Renat Yakupov, Laura Dobisch, Coraline D. Metzger, Wenzel Glanz, Michael Ewers, Peter Dechent, John­–Dylan Haynes, Klaus Scheffler, Nina Roy, Ayda Rostamzadeh, Charlotte E. Teunissen, Natalie L. Marchant, Annika Spottke, Mathias Jucker, Eicke Latz, Michael Wagner, David Mengel, Matthis Synofzik, Frank Jessen, Alfredo Ramı́rez, Agustı́n Ruiz, Michael T. Heneka

    Vydáno 2022
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  12. 12
    Plasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS

    Plasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS Autor Madhurima Chatterjee, Selcuk Özdemir, Christian Fritz, Wiebke Möbius, Luca Kleineidam, Eckhard Mandelkow�, Jacek Biernat, Cem Doğdu, Oliver Peters, Nicoleta Carmen Cosma, Xiao Wang, Luisa‐Sophie Schneider, Josef Priller, Eike Jakob Spruth, Andrea A. Kühn, Patricia Krause, Thomas Klockgether, Ina R. Vogt, Okka Kimmich, Annika Spottke, Daniel C. Hoffmann, Klaus Fließbach, Carolin Miklitz, Cornelia McCormick, Patrick Weydt, Björn Falkenburger, Moritz Brandt, René Guenther, Elisabeth Dinter, Jens Wiltfang, Niels Hansen, Mathias Bähr, Inga Zerr, Agnes Flöel, Peter J. Nestor, Emrah Düzel, Wenzel Glanz, Enise I. Incesoy, Katharina Bürger, Daniel Janowitz, Robert Perneczky, Boris‐Stephan Rauchmann, Franziska Hopfner, Olivia Wagemann, Johannes Levin, Stefan Teipel, Ingo Kilimann, Doreen Göerß, Johannes Prudlo, Thomas Gasser, Kathrin Brockmann, David Mengel, Milan Zimmermann, Matthis Synofzik, Carlo Wilke, Judit Selma‐González, Janina Turón‐Sans, Miguel Santos‐Santos, Daniel Alcolea, Sara Rubio‐Guerra, Juan Fortea, Álvaro Carbayo, Alberto Lleó, Ricardo Rojas‐García, Ignacio Illán‐Gala, Michael Wagner, Ingo Frommann, Sandra Roeske, L Bertram, Michael T. Heneka, Frederic Brosseron, Alfredo Ramı́rez, Matthias Schmid, Rudi Beschorner, Annett Halle, Jochen Herms, Manuela Neumann, Nicolas R. Barthélemy, Randall J. Bateman, Patrizia Rizzu, Peter Heutink, Oriol Dols‐Icardo, Günter U. Höglinger, Andreas Hermann, Anja Schneider

    Vydáno 2024
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  13. 13
    A systematic review of progranulin concentrations in biofluids in over 7,000 people—assessing the pathogenicity of GRN mutations and other influencing factors

    A systematic review of progranulin concentrations in biofluids in over 7,000 people—assessing the pathogenicity of GRN mutations and other influencing factors Autor Imogen J. Swift, Rosa Rademakers, NiCole A. Finch, Matt Baker, Roberta Ghidoni, Luisa Benussi, Giuliano Binetti, Giacomina Rossi, Matthis Synofzik, Carlo Wilke, David Mengel, Caroline Graff, Leonel Tadao Takada, Raquel Sánchez‐Valle, Anna Antonell, Daniela Galimberti, Chiara Fenoglio, María Serpente, Marina Arcaro, Stefanie Schreiber, Stefan Vielhaber, Philipp Arndt, Isabel Santana, Maria Rosário Almeida, Fermín Moreno, Myriam Barandiarán, Alazne Gabilondo, Johannes Stubert, Estrella Gómez‐Tortosa, Pablo Agüero, María José Sainz, Tomohito Gohda, Maki Murakoshi, Nozomu Kamei, Sarah Kittel‐Schneider, Andreas Reif, Johannes Weigl, Jinlong Jian, Liu C, Ginette Serrero, Thomas Greither, Gerit Theil, Ebba Lohmann, Stefano Gazzina, Silvia Bagnoli, Giovanni Coppola, Amalia C. Bruni, Mirja Quante, Wieland Kieß, Andreas Hiemisch, Anne Jurkutat, Matthew S. Block, Aaron Carlson, Geir Bråthen, Sigrid Botne Sando, Gøril Rolfseng Grøntvedt, Camilla Lauridsen, Amanda Heslegrave, Carolin Heller, Emily K. Abel, Alba Gómez‐Núñez, Roger Puey, Andrea Arighi, Enmanuela Rotondo, Lize C. Jiskoot, Lieke Meeter, João Durães, Marisa Lima, Miguel Tábuas‐Pereira, João Lemos, Bradley F. Boeve, Ronald C. Petersen, Dennis W. Dickson, Neill R. Graff‐Radford, Isabelle Leber, Leila Sellami, Foudil Lamari, Fabienne Clot, Barbara Borroni, Valentina Cantoni, Jasmine Rivolta, Alberto Lleó, Juan Fortea, Daniel Alcolea, Ignacio Illán‐Gala, Lucie Andres-Cerezo, Philip Van Damme, Jordi Clarimón, Petra Steinacker, Emily Feneberg, Markus Otto, Emma L. van der Ende, John C. van Swieten, Harro Seelaar, Henrik Zetterberg, Aitana Sogorb‐Esteve, Jonathan D. Rohrer

    Vydáno 2024
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