Search Results - David E. Nichols

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  1. 1
    Structure–activity relationships of serotonin 5‐HT<sub>2A</sub> agonists

    Structure–activity relationships of serotonin 5‐HT<sub>2A</sub> agonists by David E. Nichols

    Published 2012
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  2. 2
    Psychedelics

    Psychedelics by David E. Nichols

    Published 2016
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  3. 3
    Entactogens: How the Name for a Novel Class of Psychoactive Agents Originated

    Entactogens: How the Name for a Novel Class of Psychoactive Agents Originated by David E. Nichols

    Published 2022
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  4. 4
    The History of Psychedelics in Psychiatry

    The History of Psychedelics in Psychiatry by David E. Nichols, Hannes Walter

    Published 2020
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  5. 5
    An animal model of schizophrenia based on chronic LSD administration: Old idea, new results

    An animal model of schizophrenia based on chronic LSD administration: Old idea, new results by Danuta Marona‐Lewicka, Charles D. Nichols, David E. Nichols

    Published 2011
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  6. 6
    5-HT2A Receptors: Pharmacology and Functional Selectivity

    5-HT2A Receptors: Pharmacology and Functional Selectivity by Benjamin Cummins, Gerald Billac, David E. Nichols, Charles D. Nichols

    Published 2025
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  7. 7
    Chronic LSD alters gene expression profiles in the mPFC relevant to schizophrenia

    Chronic LSD alters gene expression profiles in the mPFC relevant to schizophrenia by David Martin, Danuta Marona‐Lewicka, David E. Nichols, Charles D. Nichols

    Published 2014
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  8. 8
    Characterization of Gαs and Gαolf activation by catechol and non-catechol dopamine D1 receptor agonists

    Characterization of Gαs and Gαolf activation by catechol and non-catechol dopamine D1 receptor agonists by Anh Minh Nguyen, Ana Semeano, Vianna Quach, Asuka Inoue, David E. Nichols, Hideaki Yano

    Published 2025
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  9. 9
    High specific activity tritium-labeled N-(2-methoxybenzyl)-2,5-dimethoxy-4-iodophenethylamine (INBMeO): A high-affinity 5-HT2A receptor-selective agonist radioligand

    High specific activity tritium-labeled N-(2-methoxybenzyl)-2,5-dimethoxy-4-iodophenethylamine (INBMeO): A high-affinity 5-HT2A receptor-selective agonist radioligand by David E. Nichols, Stewart Frescas, Benjamin R. Chemel, Kenneth Rehder, Desong Zhong, Anita H. Lewin

    Published 2008
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  10. 10
    <i>N</i>-Benzyl-5-methoxytryptamines as Potent Serotonin 5-HT<sub>2</sub> Receptor Family Agonists and Comparison with a Series of Phenethylamine Analogues

    <i>N</i>-Benzyl-5-methoxytryptamines as Potent Serotonin 5-HT<sub>2</sub> Receptor Family Agonists and Comparison with a Series of Phenethylamine Analogues by David E. Nichols, Maria F. Sassano, Adam L. Halberstadt, Landon M. Klein, Simon D. Brandt, Simon Elliott, Wolfgang Fiedler

    Published 2014
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  11. 11
    Mapping the Catechol Binding Site in Dopamine D<sub>1</sub>Receptors: Synthesis and Evaluation of Two Parallel Series of Bicyclic Dopamine Analogues

    Mapping the Catechol Binding Site in Dopamine D<sub>1</sub>Receptors: Synthesis and Evaluation of Two Parallel Series of Bicyclic Dopamine Analogues by Lisa A. Bonner, Uros Laban, Benjamin R. Chemel, Jose I. Juncosa, Markus A. Lill, Val J. Watts, David E. Nichols

    Published 2011
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  12. 12
    Dihydrexidine, a full dopamine D1 agonist, reduces MPTP-ioduced parkinsonism in monkeys

    Dihydrexidine, a full dopamine D1 agonist, reduces MPTP-ioduced parkinsonism in monkeys by Jane R. Taylor, Matthew S Lawrence, D. Eugene Redmond, John D. Elsworth, Robert H. Roth, David E. Nichols, Richard B. Mailman

    Published 1991
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  13. 13
    Microdosing psychedelics: More questions than answers? An overview and suggestions for future research

    Microdosing psychedelics: More questions than answers? An overview and suggestions for future research by Kim P. C. Kuypers, Livia Ng, David Erritzøe, Gitte M. Knudsen, Charles D. Nichols, David E. Nichols, Luca Pani, Anaïs Soula, David Nutt

    Published 2019
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  14. 14
    Extensive Rigid Analogue Design Maps the Binding Conformation of Potent <i>N</i>-Benzylphenethylamine 5-HT<sub>2A</sub> Serotonin Receptor Agonist Ligands

    Extensive Rigid Analogue Design Maps the Binding Conformation of Potent <i>N</i>-Benzylphenethylamine 5-HT<sub>2A</sub> Serotonin Receptor Agonist Ligands by Jose I. Juncosa, Martin Hansen, Lisa A. Bonner, Juan Pablo Cueva, Rebecca L. Maglathlin, John D. McCorvy, Danuta Marona‐Lewicka, Markus A. Lill, David E. Nichols

    Published 2012
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  15. 15
    The G Protein–Biased <i>κ</i>-Opioid Receptor Agonist RB-64 Is Analgesic with a Unique Spectrum of Activities In Vivo

    The G Protein–Biased <i>κ</i>-Opioid Receptor Agonist RB-64 Is Analgesic with a Unique Spectrum of Activities In Vivo by Kate L. White, J. Elliott Robinson, Hu Zhu, Jeffrey F. DiBerto, Prabhakar R. Polepally, Jordan K. Zjawiony, David E. Nichols, C. J. Malanga, Bryan L. Roth

    Published 2014
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  16. 16
    Return of the lysergamides. Part II: Analytical and behavioural characterization of <i>N</i><sup>6</sup>‐allyl‐6‐norlysergic acid diethylamide (AL‐LAD) and (2’<i>S</i>,4’<i>S</i>)‐lysergic acid 2,4‐dimethylazetidide (LSZ)

    Return of the lysergamides. Part II: Analytical and behavioural characterization of <i>N</i><sup>6</sup>‐allyl‐6‐norlysergic acid diethylamide (AL‐LAD) and (2’<i>S</i>,4’<i>S</i>)‐... by Simon D. Brandt, Pierce V. Kavanagh, Folker Westphal, Simon Elliott, Jason Wallach, Tristan Colestock, Timothy E. Burrow, Stephen J. Chapman, Alexander Stratford, David E. Nichols, Adam L. Halberstadt

    Published 2016
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  17. 17
    Return of the lysergamides. Part IV: Analytical and pharmacological characterization of lysergic acid morpholide (LSM‐775)

    Return of the lysergamides. Part IV: Analytical and pharmacological characterization of lysergic acid morpholide (LSM‐775) by Simon D. Brandt, Pierce V. Kavanagh, Brendan Twamley, Folker Westphal, Simon Elliott, Jason Wallach, Alexander Stratford, Landon M. Klein, John D. McCorvy, David E. Nichols, Adam L. Halberstadt

    Published 2017
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  18. 18
    Structure of a Hallucinogen-Activated Gq-Coupled 5-HT2A Serotonin Receptor

    Structure of a Hallucinogen-Activated Gq-Coupled 5-HT2A Serotonin Receptor by Kuglae Kim, Tao Che, Ouliana Panova, Jeffrey F. DiBerto, Jiankun Lyu, B. Krumm, Daniel Wacker, Michael J. Robertson, Alpay B. Seven, David E. Nichols, Brian K. Shoichet, Georgios Skiniotis, Bryan L. Roth

    Published 2020
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  19. 19
    Crystal Structure of an LSD-Bound Human Serotonin Receptor

    Crystal Structure of an LSD-Bound Human Serotonin Receptor by Daniel Wacker, Sheng Wang, John D. McCorvy, Robin M. Betz, AJ Venkatakrishnan, Anat Levit, Katherine Lansu, Zachary L. Schools, Tao Che, David E. Nichols, Brian K. Shoichet, Ron O. Dror, Bryan L. Roth

    Published 2017
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  20. 20
    Ligand and G-protein selectivity in the κ-opioid receptor

    Ligand and G-protein selectivity in the κ-opioid receptor by Jianming Han, Jingying Zhang, Antonina L. Nazarova, Sarah M. Bernhard, B. Krumm, Lei Zhao, Jordy Homing Lam, Vipin A. Rangari, Susruta Majumdar, David E. Nichols, Vsevolod Katritch, Peng Yuan, Jonathan F. Fay, Tao Che

    Published 2023
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