Ngā hua rapu - David E. Heppner

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  1. 1
    Lazertinib: Breaking the mold of third-generation EGFR inhibitors

    Lazertinib: Breaking the mold of third-generation EGFR inhibitors mā Kishan B. Patel, David E. Heppner

    I whakaputaina 2025
    Whiwhi kuputuhi katoa
    Revisão
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  2. 2
    Redox-dependent regulation of epidermal growth factor receptor signaling

    Redox-dependent regulation of epidermal growth factor receptor signaling mā David E. Heppner, Albert van der Vliet

    I whakaputaina 2015
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  3. 3
    Molecular Origin of Rapid versus Slow Intramolecular Electron Transfer in the Catalytic Cycle of the Multicopper Oxidases

    Molecular Origin of Rapid versus Slow Intramolecular Electron Transfer in the Catalytic Cycle of the Multicopper Oxidases mā David E. Heppner, Christian H. Kjaergaard, Edward I. Solomon

    I whakaputaina 2013
    Whiwhi kuputuhi katoa
    Artigo
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  4. 4
    Dual oxidase: a novel therapeutic target in allergic disease

    Dual oxidase: a novel therapeutic target in allergic disease mā Albert van der Vliet, Karamatullah Danyal, David E. Heppner

    I whakaputaina 2018
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Revisão
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  5. 5
    The role of sulfenic acids in cellular redox signaling: Reconciling chemical kinetics and molecular detection strategies

    The role of sulfenic acids in cellular redox signaling: Reconciling chemical kinetics and molecular detection strategies mā David E. Heppner, Yvonne Janssen‐Heininger, Albert van der Vliet

    I whakaputaina 2017
    Whiwhi kuputuhi katoa
    Artigo
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  6. 6
    Structural Basis for EGFR Mutant Inhibition by Trisubstituted Imidazole Inhibitors

    Structural Basis for EGFR Mutant Inhibition by Trisubstituted Imidazole Inhibitors mā David E. Heppner, Marcel Günther, Florian Wittlinger, Stefan Laufer, Michael J. Eck

    I whakaputaina 2020
    Whiwhi kuputuhi katoa
    Artigo
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  7. 7
    Redox regulation of tyrosine kinase signalling: more than meets the eye

    Redox regulation of tyrosine kinase signalling: more than meets the eye mā Christopher M. Dustin, David E. Heppner, Miao-chong J. Lin, Albert van der Vliet

    I whakaputaina 2019
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
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  8. 8
    The NADPH Oxidases DUOX1 and NOX2 Play Distinct Roles in Redox Regulation of Epidermal Growth Factor Receptor Signaling

    The NADPH Oxidases DUOX1 and NOX2 Play Distinct Roles in Redox Regulation of Epidermal Growth Factor Receptor Signaling mā David E. Heppner, Milena Hristova, Christopher M. Dustin, Karamatullah Danyal, Aida Habibovic, Albert van der Vliet

    I whakaputaina 2016
    Whiwhi kuputuhi katoa
    Artigo
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  9. 9
    Paradoxical roles of dual oxidases in cancer biology

    Paradoxical roles of dual oxidases in cancer biology mā Andrew C. Little, Arvis Sulovari, Karamatullah Danyal, David E. Heppner, David J. Seward, Albert van der Vliet

    I whakaputaina 2017
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  10. 10
    Reaction Coordinate of a Functional Model of Tyrosinase: Spectroscopic and Computational Characterization

    Reaction Coordinate of a Functional Model of Tyrosinase: Spectroscopic and Computational Characterization mā Bryan T. Op’t Holt, M.A. Vance, Liviu M. Mirica, David E. Heppner, T. Daniel P. Stack, Edward I. Solomon

    I whakaputaina 2009
    Whiwhi kuputuhi katoa
    Artigo
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  11. 11
    Architecture of the NADPH oxidase family of enzymes

    Architecture of the NADPH oxidase family of enzymes mā Blessing C. Ogboo, Uriy V. Grabovyy, Aniket Maini, Scott Scouten, Albert van der Vliet, Andrea Mattevi, David E. Heppner

    I whakaputaina 2022
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  12. 12
    Pitfalls and Considerations in Determining the Potency and Mutant Selectivity of Covalent Epidermal Growth Factor Receptor Inhibitors

    Pitfalls and Considerations in Determining the Potency and Mutant Selectivity of Covalent Epidermal Growth Factor Receptor Inhibitors mā Kristopher W. Hoyt, Daniel A. Urul, Blessing C. Ogboo, Florian Wittlinger, Stefan Laufer, Erik Schaefer, Earl W. May, David E. Heppner

    I whakaputaina 2023
    Whiwhi kuputuhi katoa
    Artigo
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  13. 13
    DUOX1 silencing in lung cancer promotes EMT, cancer stem cell characteristics and invasive properties

    DUOX1 silencing in lung cancer promotes EMT, cancer stem cell characteristics and invasive properties mā Andrew C. Little, Derek Sham, Milena Hristova, Karamatullah Danyal, David E. Heppner, R Bauer, Lynn Sipsey, Aida Habibovic, Albert van der Vliet

    I whakaputaina 2016
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  14. 14
    Copper Active Sites in Biology

    Copper Active Sites in Biology mā Edward I. Solomon, David E. Heppner, Esther M. Johnston, Jake W. Ginsbach, Jordi Cirera, Munzarin F. Qayyum, Matthew T. Kieber‐Emmons, Christian H. Kjaergaard, Ryan G. Hadt, Li Tian

    I whakaputaina 2014
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  15. 15
    Cysteine perthiosulfenic acid (Cys-SSOH): A novel intermediate in thiol-based redox signaling?

    Cysteine perthiosulfenic acid (Cys-SSOH): A novel intermediate in thiol-based redox signaling? mā David E. Heppner, Milena Hristova, Tomoaki Ida, Ana Mijušković, Christopher M. Dustin, Virág Bogdándi, Jon M. Fukuto, Tobias P. Dick, Péter Nagy, Jianing Li, Takaaki Akaike, Albert van der Vliet

    I whakaputaina 2017
    Whiwhi kuputuhi katoa
    Artigo
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  16. 16
    Direct cysteine sulfenylation drives activation of the Src kinase

    Direct cysteine sulfenylation drives activation of the Src kinase mā David E. Heppner, Christopher M. Dustin, Chenyi Liao, Milena Hristova, Carmen Veith, Andrew C. Little, Bethany A. Ahlers, Sheryl L. White, Bin Deng, Ying‐Wai Lam, Jianing Li, Albert van der Vliet

    I whakaputaina 2018
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  17. 17
    Lung epithelial protein disulfide isomerase A3 (PDIA3) plays an important role in influenza infection, inflammation, and airway mechanics

    Lung epithelial protein disulfide isomerase A3 (PDIA3) plays an important role in influenza infection, inflammation, and airway mechanics mā Nicolas Chamberlain, Bethany R. Korwin-Mihavics, Emily M. Nakada, S. Bruno, David E. Heppner, David G. Chapman, Sidra M. Hoffman, Albert van der Vliet, Benjamin T. Suratt, Oliver Dienz, John F. Alcorn, Vikas Anathy

    I whakaputaina 2019
    Whiwhi kuputuhi katoa
    Artigo
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  18. 18
    Molecular basis for cooperative binding and synergy of ATP-site and allosteric EGFR inhibitors

    Molecular basis for cooperative binding and synergy of ATP-site and allosteric EGFR inhibitors mā Tyler S. Beyett, Ciric To, David E. Heppner, Jaimin K. Rana, Anna M. Schmoker, Jaebong Jang, Dries J.H. De Clercq, Gabriel Gómez, David A. Scott, Nathanael S. Gray, Pasi A. Jänne, Michael J. Eck

    I whakaputaina 2022
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  19. 19
    DUOX1 mediates persistent epithelial EGFR activation, mucous cell metaplasia, and airway remodeling during allergic asthma

    DUOX1 mediates persistent epithelial EGFR activation, mucous cell metaplasia, and airway remodeling during allergic asthma mā Aida Habibovic, Milena Hristova, David E. Heppner, Karamatullah Danyal, Jennifer L. Ather, Yvonne Janssen‐Heininger, Charles G. Irvin, Matthew E. Poynter, Lennart K. A. Lundblad, Anne E. Dixon, Miklós Geiszt, Albert van der Vliet

    I whakaputaina 2016
    Whiwhi kuputuhi katoa Whiwhi kuputuhi katoa
    Artigo
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  20. 20
    Discovery and Optimization of Dibenzodiazepinones as Allosteric Mutant-Selective EGFR Inhibitors

    Discovery and Optimization of Dibenzodiazepinones as Allosteric Mutant-Selective EGFR Inhibitors mā Dries J.H. De Clercq, David E. Heppner, Ciric To, Jaebong Jang, Eunyoung Park, Cai‐Hong Yun, Mierzhati Mushajiang, Bo Hee Shin, Thomas W. Gero, David A. Scott, Pasi A. Jänne, Michael J. Eck, Nathanael S. Gray

    I whakaputaina 2019
    Whiwhi kuputuhi katoa
    Artigo
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