תוצאות חיפוש - David E. Heppner
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Lazertinib: Breaking the mold of third-generation EGFR inhibitors מאת Kishan B. Patel, David E. Heppner
יצא לאור 2025Revisão -
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Redox-dependent regulation of epidermal growth factor receptor signaling מאת David E. Heppner, Albert van der Vliet
יצא לאור 2015Revisão -
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Pitfalls and Considerations in Determining the Potency and Mutant Selectivity of Covalent Epidermal Growth Factor Receptor Inhibitors מאת Kristopher W. Hoyt, Daniel A. Urul, Blessing C. Ogboo, Florian Wittlinger, Stefan Laufer, Erik Schaefer, Earl W. May, David E. Heppner
יצא לאור 2023Artigo -
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Cysteine perthiosulfenic acid (Cys-SSOH): A novel intermediate in thiol-based redox signaling? מאת David E. Heppner, Milena Hristova, Tomoaki Ida, Ana Mijušković, Christopher M. Dustin, Virág Bogdándi, Jon M. Fukuto, Tobias P. Dick, Péter Nagy, Jianing Li, Takaaki Akaike, Albert van der Vliet
יצא לאור 2017Artigo -
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Direct cysteine sulfenylation drives activation of the Src kinase מאת David E. Heppner, Christopher M. Dustin, Chenyi Liao, Milena Hristova, Carmen Veith, Andrew C. Little, Bethany A. Ahlers, Sheryl L. White, Bin Deng, Ying‐Wai Lam, Jianing Li, Albert van der Vliet
יצא לאור 2018Artigo -
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Lung epithelial protein disulfide isomerase A3 (PDIA3) plays an important role in influenza infection, inflammation, and airway mechanics מאת Nicolas Chamberlain, Bethany R. Korwin-Mihavics, Emily M. Nakada, S. Bruno, David E. Heppner, David G. Chapman, Sidra M. Hoffman, Albert van der Vliet, Benjamin T. Suratt, Oliver Dienz, John F. Alcorn, Vikas Anathy
יצא לאור 2019Artigo -
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Molecular basis for cooperative binding and synergy of ATP-site and allosteric EGFR inhibitors מאת Tyler S. Beyett, Ciric To, David E. Heppner, Jaimin K. Rana, Anna M. Schmoker, Jaebong Jang, Dries J.H. De Clercq, Gabriel Gómez, David A. Scott, Nathanael S. Gray, Pasi A. Jänne, Michael J. Eck
יצא לאור 2022Artigo -
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DUOX1 mediates persistent epithelial EGFR activation, mucous cell metaplasia, and airway remodeling during allergic asthma מאת Aida Habibovic, Milena Hristova, David E. Heppner, Karamatullah Danyal, Jennifer L. Ather, Yvonne Janssen‐Heininger, Charles G. Irvin, Matthew E. Poynter, Lennart K. A. Lundblad, Anne E. Dixon, Miklós Geiszt, Albert van der Vliet
יצא לאור 2016Artigo -
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Discovery and Optimization of Dibenzodiazepinones as Allosteric Mutant-Selective EGFR Inhibitors מאת Dries J.H. De Clercq, David E. Heppner, Ciric To, Jaebong Jang, Eunyoung Park, Cai‐Hong Yun, Mierzhati Mushajiang, Bo Hee Shin, Thomas W. Gero, David A. Scott, Pasi A. Jänne, Michael J. Eck, Nathanael S. Gray
יצא לאור 2019Artigo
כלי חיפוש:
נושאים קשורים
Biology
Biochemistry
Chemistry
Epidermal growth factor receptor
Receptor
Enzyme
Gene
Cancer research
Cell biology
EGFR inhibitors
Organic chemistry
Cancer
Mutant
Allosteric regulation
Gefitinib
Genetics
Medicine
T790M
Tyrosine kinase
Computational biology
Erlotinib
Internal medicine
Kinase
Reactive oxygen species
Signal transduction
Stereochemistry
Biophysics
Combinatorial chemistry
Cysteine
NADPH oxidase