Αποτελέσματα αναζήτησης - David E. Heppner
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Pitfalls and Considerations in Determining the Potency and Mutant Selectivity of Covalent Epidermal Growth Factor Receptor Inhibitors από Kristopher W. Hoyt, Daniel A. Urul, Blessing C. Ogboo, Florian Wittlinger, Stefan Laufer, Erik Schaefer, Earl W. May, David E. Heppner
Έκδοση 2023Artigo -
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DUOX1 silencing in lung cancer promotes EMT, cancer stem cell characteristics and invasive properties από Andrew C. Little, Derek Sham, Milena Hristova, Karamatullah Danyal, David E. Heppner, R Bauer, Lynn Sipsey, Aida Habibovic, Albert van der Vliet
Έκδοση 2016Artigo -
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Cysteine perthiosulfenic acid (Cys-SSOH): A novel intermediate in thiol-based redox signaling? από David E. Heppner, Milena Hristova, Tomoaki Ida, Ana Mijušković, Christopher M. Dustin, Virág Bogdándi, Jon M. Fukuto, Tobias P. Dick, Péter Nagy, Jianing Li, Takaaki Akaike, Albert van der Vliet
Έκδοση 2017Artigo -
16
Direct cysteine sulfenylation drives activation of the Src kinase από David E. Heppner, Christopher M. Dustin, Chenyi Liao, Milena Hristova, Carmen Veith, Andrew C. Little, Bethany A. Ahlers, Sheryl L. White, Bin Deng, Ying‐Wai Lam, Jianing Li, Albert van der Vliet
Έκδοση 2018Artigo -
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Lung epithelial protein disulfide isomerase A3 (PDIA3) plays an important role in influenza infection, inflammation, and airway mechanics από Nicolas Chamberlain, Bethany R. Korwin-Mihavics, Emily M. Nakada, S. Bruno, David E. Heppner, David G. Chapman, Sidra M. Hoffman, Albert van der Vliet, Benjamin T. Suratt, Oliver Dienz, John F. Alcorn, Vikas Anathy
Έκδοση 2019Artigo -
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Molecular basis for cooperative binding and synergy of ATP-site and allosteric EGFR inhibitors από Tyler S. Beyett, Ciric To, David E. Heppner, Jaimin K. Rana, Anna M. Schmoker, Jaebong Jang, Dries J.H. De Clercq, Gabriel Gómez, David A. Scott, Nathanael S. Gray, Pasi A. Jänne, Michael J. Eck
Έκδοση 2022Artigo -
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DUOX1 mediates persistent epithelial EGFR activation, mucous cell metaplasia, and airway remodeling during allergic asthma από Aida Habibovic, Milena Hristova, David E. Heppner, Karamatullah Danyal, Jennifer L. Ather, Yvonne Janssen‐Heininger, Charles G. Irvin, Matthew E. Poynter, Lennart K. A. Lundblad, Anne E. Dixon, Miklós Geiszt, Albert van der Vliet
Έκδοση 2016Artigo -
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Discovery and Optimization of Dibenzodiazepinones as Allosteric Mutant-Selective EGFR Inhibitors από Dries J.H. De Clercq, David E. Heppner, Ciric To, Jaebong Jang, Eunyoung Park, Cai‐Hong Yun, Mierzhati Mushajiang, Bo Hee Shin, Thomas W. Gero, David A. Scott, Pasi A. Jänne, Michael J. Eck, Nathanael S. Gray
Έκδοση 2019Artigo
Εργαλεία αναζήτησης:
Σχετικά θέματα
Biology
Biochemistry
Chemistry
Epidermal growth factor receptor
Receptor
Enzyme
Gene
Cancer research
Cell biology
EGFR inhibitors
Organic chemistry
Cancer
Mutant
Allosteric regulation
Gefitinib
Genetics
Medicine
T790M
Tyrosine kinase
Computational biology
Erlotinib
Internal medicine
Kinase
Reactive oxygen species
Signal transduction
Stereochemistry
Biophysics
Combinatorial chemistry
Cysteine
NADPH oxidase