Ngā hua rapu - David E. Ehmann
- E whakaatu ana i te 1 - 12 hua o te 12
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Novel compounds targeting bacterial DNA topoisomerase/DNA gyrase mā David E. Ehmann, Sushmita D. Lahiri
I whakaputaina 2014Revisão -
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The EntF and EntE adenylation domains of <i>Escherichia coli</i> enterobactin synthetase: Sequestration and selectivity in acyl-AMP transfers to thiolation domain cosubstrates mā David E. Ehmann, Cathryn A. Shaw-Reid, Heather C. Losey, Christopher T. Walsh
I whakaputaina 2000Artigo -
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NBTI 5463 Is a Novel Bacterial Type II Topoisomerase Inhibitor with Activity against Gram-Negative Bacteria and <i>In Vivo</i> Efficacy mā Thomas J. Dougherty, Asha S. Nayar, Joseph Newman, Sussie Hopkins, Gregory G. Stone, Michele Johnstone, Adam B. Shapiro, Mark T.D. Cronin, Folkert Reck, David E. Ehmann
I whakaputaina 2014Artigo -
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Inhibition of Neisseria gonorrhoeae Type II Topoisomerases by the Novel Spiropyrimidinetrione AZD0914 mā Günther Kern, Tiffany Palmer, David E. Ehmann, Adam B. Shapiro, Beth Andrews, Gregory S. Basarab, P. Doig, Jun Fan, Ning Gao, Scott D. Mills, John P. Mueller, Shubha Sriram, Jason Thresher, Grant K. Walkup
I whakaputaina 2015Artigo -
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Molecular Mechanisms of Sulbactam Antibacterial Activity and Resistance Determinants in Acinetobacter baumannii mā William F. Penwell, Adam B. Shapiro, R.A. Giacobbe, Rong-Fang Gu, Ning Gao, Jason Thresher, Robert E. McLaughlin, Michael D. Huband, Boudewijn L DeJonge, David E. Ehmann, Alita A. Miller
I whakaputaina 2015Artigo -
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Kinetics of Avibactam Inhibition against Class A, C, and D β-Lactamases mā David E. Ehmann, Haris Jahić, Philip L. Ross, Rong-Fang Gu, Jun Hu, Thomas F. Durand‐Reville, Sushmita D. Lahiri, Jason Thresher, Stephania Livchak, Ning Gao, Tiffany Palmer, Grant K. Walkup, Stewart L. Fisher
I whakaputaina 2013Artigo -
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Myostatin and activin blockade by engineered follistatin results in hypertrophy and improves dystrophic pathology in mdx mouse more than myostatin blockade alone mā Andrea Iskenderian, Nan Liu, Qingwei Deng, Yan Huang, Chuan Shen, Kathleen Palmieri, Robert Crooker, Dianna Lundberg, Niksa Kastrapeli, Brian Pescatore, Alla Romashko, John Dumas, Robert D. Comeau, Angela W. Norton, Jing Pan, Haojing Rong, Katayoun Derakhchan, David E. Ehmann
I whakaputaina 2018Artigo -
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Pharmacodynamic Profiling of a Siderophore-Conjugated Monocarbam in Pseudomonas aeruginosa: Assessing the Risk for Resistance and Attenuated Efficacy mā Aryun Kim, Amy Kutschke, David E. Ehmann, Sara A. Patey, Jared L. Crandon, Elise Gorseth, Alita A. Miller, Robert E. McLaughlin, Christina M. Blinn, April Chen, Asha S. Nayar, Brian Dangel, Andy S. Tsai, Michael Rooney, Kerry E. Murphy-Benenato, Ann E. Eakin, David P. Nicolau
I whakaputaina 2015Artigo -
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Translating slow-binding inhibition kinetics into cellular and in vivo effects mā Grant K. Walkup, Zhiping You, Philip L. Ross, Eleanor K. H. Allen, Fereidoon Daryaee, Michael Hale, John C. O’Donnell, David E. Ehmann, Virna Schuck, Ed T. Buurman, Allison L. Choy, Laurel Hajec, Kerry E. Murphy-Benenato, Valerie Marone, Sara A. Patey, Lena A Grosser, Michele Johnstone, Stephen G. Walker, Peter J. Tonge, Stewart L. Fisher
I whakaputaina 2015Artigo
Ngā utauta rapu:
Ngā marau whai pānga
Biology
Biochemistry
Chemistry
Escherichia coli
Gene
Genetics
Bacteria
Microbiology
Antibiotics
Enzyme
Pseudomonas aeruginosa
Stereochemistry
DNA
DNA gyrase
In vivo
Pharmacology
Topoisomerase
Acylation
Biosynthesis
Biotechnology
Catalysis
Computational biology
Covalent bond
Enterobacteriaceae
Kinetics
Medicine
Nonribosomal peptide
Organic chemistry
Pharmacodynamics
Pharmacokinetics