Søgeresultater - David C. Wedge

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  1. 1
    A unified haplotype-based method for accurate and comprehensive variant calling

    A unified haplotype-based method for accurate and comprehensive variant calling af Daniel P. Cooke, David C. Wedge, Gerton Lunter

    Udgivet 2021
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  2. 2
    Principles of Reconstructing the Subclonal Architecture of Cancers

    Principles of Reconstructing the Subclonal Architecture of Cancers af Stefan C. Dentro, David C. Wedge, Peter Van Loo

    Udgivet 2017
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  3. 3
    APOBEC3 mutational signatures are associated with extensive and diverse genomic instability across multiple tumour types

    APOBEC3 mutational signatures are associated with extensive and diverse genomic instability across multiple tumour types af G. Maria Jakobsdottir, Daniel Brewer, Colin Cooper, Catherine Green, David C. Wedge

    Udgivet 2022
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  4. 4
    Deciphering Signatures of Mutational Processes Operative in Human Cancer

    Deciphering Signatures of Mutational Processes Operative in Human Cancer af Ludmil B. Alexandrov, Serena Nik‐Zainal, David C. Wedge, Peter J. Campbell, Michael R. Stratton

    Udgivet 2013
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  5. 5
    Analysis of a complete DNA–protein affinity landscape

    Analysis of a complete DNA–protein affinity landscape af William Rowe, Mark Platt, David C. Wedge, Philip J. Day, Douglas B. Kell, Joshua Knowles

    Udgivet 2009
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  6. 6
    Tumor heterogeneity

    Tumor heterogeneity af Dana Pe’er, Seishi Ogawa, Ofer Elhanani, Leeat Keren, Trudy G. Oliver, David C. Wedge

    Udgivet 2021
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  7. 7
    Clock-like mutational processes in human somatic cells

    Clock-like mutational processes in human somatic cells af Ludmil B. Alexandrov, Philip H. Jones, David C. Wedge, Julian E. Sale, Peter J. Campbell, Serena Nik‐Zainal, Michael R. Stratton

    Udgivet 2015
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  8. 8
    A practical guide to cancer subclonal reconstruction from DNA sequencing

    A practical guide to cancer subclonal reconstruction from DNA sequencing af Maxime Tarabichi, Adriana Salcedo, Amit G. Deshwar, Máire Ní Leathlobhair, Jeff Wintersinger, David C. Wedge, Peter Van Loo, Quaid Morris, Paul C. Boutros

    Udgivet 2021
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  9. 9
    Automated workflows for accurate mass-based putative metabolite identification in LC/MS-derived metabolomic datasets

    Automated workflows for accurate mass-based putative metabolite identification in LC/MS-derived metabolomic datasets af Marie Brown, David C. Wedge, Royston Goodacre, Douglas B. Kell, Philip N. Baker, Louise C. Kenny, Mamas A. Mamas, Ludwig Neyses, Warwick B. Dunn

    Udgivet 2011
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  10. 10
    Neutral tumor evolution?

    Neutral tumor evolution? af Maxime Tarabichi, Iñigo Martincorena, Moritz Gerstung, Armand M. Leroi, Florian Markowetz, Paul T. Spellman, Quaid Morris, Ole Christian Lingjærde, David C. Wedge, Peter Van Loo

    Udgivet 2018
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  11. 11
    Analysis of 10,478 cancer genomes identifies candidate driver genes and opportunities for precision oncology

    Analysis of 10,478 cancer genomes identifies candidate driver genes and opportunities for precision oncology af Ben Kinnersley, Amit Sud, Andrew Everall, Alex J. Cornish, Daniel Chubb, Richard Culliford, Andreas Gruber, Adrian Lärkeryd, Costas Mitsopoulos, David C. Wedge, Richard S. Houlston

    Udgivet 2024
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  12. 12
    Array-based evolution of DNA aptamers allows modelling of an explicit sequence-fitness landscape

    Array-based evolution of DNA aptamers allows modelling of an explicit sequence-fitness landscape af Christopher G. Knight, Mark Platt, William Rowe, David C. Wedge, Fazlur‐Rahman Nawaz Khan, Philip J. Day, Andy McShea, Joshua Knowles, Douglas B. Kell

    Udgivet 2008
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  13. 13
    Fast randomization of large genomic datasets while preserving alteration counts

    Fast randomization of large genomic datasets while preserving alteration counts af Andrea Gobbi, Francesco Iorio, Kevin J. Dawson, David C. Wedge, David Tamborero, Ludmil B. Alexandrov, Núria López-Bigas, Mathew J. Garnett, Giuseppe Jurman, Julio Sáez-Rodríguez

    Udgivet 2014
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  14. 14
    ascatNgs: Identifying Somatically Acquired Copy‐Number Alterations from Whole‐Genome Sequencing Data

    ascatNgs: Identifying Somatically Acquired Copy‐Number Alterations from Whole‐Genome Sequencing Data af Keiran Raine, Peter Van Loo, David C. Wedge, David Jones, Andrew Menzies, Adam P. Butler, Jon W. Teague, Patrick Tarpey, Serena Nik‐Zainal, Peter J. Campbell

    Udgivet 2016
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  15. 15
    DNMT3A mutations occur early or late in patients with myeloproliferative neoplasms and mutation order influences phenotype

    DNMT3A mutations occur early or late in patients with myeloproliferative neoplasms and mutation order influences phenotype af Jyoti Nangalia, Francesca Nice, David C. Wedge, Anna L. Godfrey, Jacob Grinfeld, Clare E. Thakker, Charles Massie, E. Joanna Baxter, D L Sewell, Yvonne Silber, Peter J. Campbell, Anthony R. Green

    Udgivet 2015
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  16. 16
    Hypoxia coordinates the spatial landscape of myeloid cells within glioblastoma to affect survival

    Hypoxia coordinates the spatial landscape of myeloid cells within glioblastoma to affect survival af Michael Haley, Leoma Bere, James Minshull, Sokratia Georgaka, Natalia Garcia-Martin, Gareth Howell, David Coope, Federico Roncaroli, Andrew T. King, David C. Wedge, Stuart M. Allan, Omar Pathmanaban, David Brough, Kevin N. Couper

    Udgivet 2024
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  17. 17
    Genomic copy number predicts esophageal cancer years before transformation

    Genomic copy number predicts esophageal cancer years before transformation af Sarah Killcoyne, Eleanor Gregson, David C. Wedge, Dan J. Woodcock, Matthew Eldridge, Rachel de la Rue, Ahmad Miremadi, Sujath Abbas, Adrienn Blasko, Cassandra Kosmidou, Władysław Januszewicz, Aikaterini Varanou Jenkins, Moritz Gerstung, Rebecca C. Fitzgerald

    Udgivet 2020
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  18. 18
    Comprehensive repertoire of the chromosomal alteration and mutational signatures across 16 cancer types from 10,983 cancer patients

    Comprehensive repertoire of the chromosomal alteration and mutational signatures across 16 cancer types from 10,983 cancer patients af Andrew Everall, Avraam Tapinos, Aliah Hawari, Alex J. Cornish, Amit Sud, Daniel Chubb, Ben Kinnersley, Anna Frangou, Miguel Barquín, Josephine Jung, David N. Church, Ludmil B. Alexandrov, Richard S. Houlston, Andreas Gruber, David C. Wedge

    Udgivet 2023
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  19. 19
    Genetic and epigenetic intratumor heterogeneity impacts prognosis of lung adenocarcinoma

    Genetic and epigenetic intratumor heterogeneity impacts prognosis of lung adenocarcinoma af Xing Hua, Zhao Wei, Angela Cecilia Pesatori, Dario Consonni, Neil E. Caporaso, Tongwu Zhang, Bin Zhu, Mingyi Wang, Kristine Jones, Belynda Hicks, Lei Song, Joshua N. Sampson, David C. Wedge, Jianxin Shi, Maria Teresa Landi

    Udgivet 2020
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  20. 20
    In utero origin of myelofibrosis presenting in adult monozygotic twins

    In utero origin of myelofibrosis presenting in adult monozygotic twins af Nikolaos Sousos, Máire Ní Leathlobhair, Christina Simoglou Karali, Eleni Louka, Nicola Bienz, Daniel Royston, Sally‐Ann Clark, Angela Hamblin, Kieran Howard, Vikram Mathews, Biju George, Anindita Roy, Bethan Psaila, David C. Wedge, Adam J. Mead

    Udgivet 2022
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